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Total 119 results found since Jan 2013.

Position Paper Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features seen on neuroimaging include recent small subcortical infarcts, lacunes, white matter hyperintensities, perivascular spaces, microbleeds, and brain atrophy. SVD can present as a stroke or cognitive decline, or can have few or no symptoms. SVD frequently coexists with neurodegenerative disease, and can exacerbate cognitive deficits, physical disabilities, and other symptoms of neurodegeneration. Terminology and definitions for imaging the features of SVD vary widely, which is also true for protocols for image acquisition and image analysis.
Source: Lancet Neurology - July 17, 2013 Category: Neurology Authors: Joanna M Wardlaw, Eric E Smith, Geert J Biessels, Charlotte Cordonnier, Franz Fazekas, Richard Frayne, Richard I Lindley, John T O'Brien, Frederik Barkhof, Oscar R Benavente, Sandra E Black, Carol Brayne, Monique Breteler, Hugues Chabriat, Charles DeCarli Tags: Position Paper Source Type: research

Medtronic acquires Covidien in a $43 billion deal | Medtech Wall Street news for the week of June 16, 2014
Here's a look at some of the top Wall Street stories for medical device companies this week: Blockbuster: Medtronic in $43B deal to acquire Covidien; Medtronic buyout holds $80M in golden parachutes for Covidien execs; FDA wants another panel hearing on Boston Scientific's Watchman anti-stroke device; European Commission tables review of Zimmer's $13B acquisition of Biomet; Ackman takes Allergan to court to defend against poison pill Blockbuster: Medtronic in $43B deal to acquire Covidien June 16, 2014 by Brad Perriello Zimmer Holdings, Biomet, Boston Scientific, Covidien, European Commission, Food & Drug ...
Source: Mass Device - June 19, 2014 Category: Medical Equipment Authors: MassDevice Source Type: news

Low-flow vascular malformation: Contribution of sequential postcontrast MRI acquisitions
A 50-year-old man was referred for subacute intracranial hypertension. MRI revealed a well-circumscribed lesion in the posterior fossa that was hypointense on T1-weighted imaging and hyperintense on T2-weighted imaging (figure 1, A and E). Cerebral blood volume map and sequential postcontrast T1-weighted images showed progressive increase in the homogeneity of the contrast enhancement, indicating that the lesion had low but substantial flow (figure 1, B–D). Digital subtraction angiography showed a vascular lesion with a central to peripheral pattern of vascularity and absence of early venous return (figure 1, F&ndash...
Source: Neurology - June 30, 2014 Category: Neurology Authors: Heck, O., Krainik, A., Boubagra, K., Tahon, F., Attye, A., Le Bas, J. F., Boutonnat, J., Grand, S. Tags: MRI, Other cerebrovascular disease/ Stroke NEUROIMAGES Source Type: research

How a Small Tribe Turned Tragedy into Opportunity
An Irula couple fishes in the creeks of the Pichavaram Mangrove Forest in Tamil Nadu. Credit: Malini Shankar/IPSBy Malini ShankarPICHAVARAM, India, Nov 13 2014 (IPS)When the Asian tsunami washed over several Indian Ocean Rim countries on Boxing Day 2004, it left a trail of destruction in its wake, including a death toll that touched 230,000.Millions lost their jobs, food security and traditional livelihoods and many have spent the last decade trying to pick up the pieces of their lives. But for a small tribe in southern India, the tsunami didn’t bring devastation; instead, it brought hope.Numbering some 25,000 people, th...
Source: IPS Inter Press Service - Health - November 13, 2014 Category: Global & Universal Authors: Malini Shankar Tags: Aid Asia-Pacific Biodiversity Civil Society Development & Aid Economy & Trade Editors' Choice Education Environment Featured Food & Agriculture Global Governance Headlines Health Human Rights Indigenous Rights Labour Natu Source Type: news

Stryker Betting On MAKO And Anti-Stroke Devices, Planning More Acquisitions To Drive Growth
Stryker considers its MAKO robotic surgery system and its clot removal devices as growth accelerators for the company through 2016. The artificial knee and hip implants maker is also cautiously eyeing more M&A targets after it recently acquired a number of assets.
Source: Medical Design Online News - April 23, 2015 Category: Medical Equipment Source Type: news

MassDevice.com +3 | The top 3 medtech stories for August 10, 2015
Say hello to MassDevice +3, a bite-sized view of the top three medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 3 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry.   3. NDC closes Interface Catheter buy, rebrands as Confluent Nitinol Devices & Components said it closed its acquisition of Interface Catheter Solutions and announced it will rebrand the new combined company as Confluent Medical Technologies. Confluent Medical will leverage both NDC and Interf...
Source: Mass Device - August 10, 2015 Category: Medical Equipment Authors: MassDevice Tags: Blog Plus 3 Source Type: news

Nipro to acquire Infraredx
Nipro (TYO: 8086) said today that it plans to acquire Infraredx and its cardiovascular imaging device for an undisclosed amount. Burlington, Mass.-based Infraredx makes an imaging system that combines intravascular ultrasound and near-infrared spectroscopy to provide images of the interior of coronary blood vessels. The company says the device is designed to detect lipid-core-containing plaque, which it says is implicated in higher risk for heart attack or stroke. In 2013 Nipro put down a $25 million equity investment in Infraredx, which earlier this year withdrew an initial public offering it had hoped would raise $56...
Source: Mass Device - September 11, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Cardiovascular Imaging Mergers & Acquisitions InfraReDx Inc. Nipro Source Type: news

Nipro to sell diagnostics biz to China’s Sinocare for $273m
Nipro (TYO: 8086) said today it signed a deal sell its diagnostics business to China-based Sinocare for approximately $273 in cash. Nipro Diagnostics, based in Ft. Lauderdale, Fla., develops, manufactures and markets diabetes products, including glucose monitors, the company said. “This transaction combines 1 of the fastest growing blood glucose monitoring companies in the United States with the fastest growing blood glucose monitoring company in China. We have a shared vision and a singular focus to provide innovative and affordable solutions so patients can live healthier lives. Together, we will offer a strong p...
Source: Mass Device - October 27, 2015 Category: Medical Equipment Authors: Fink Densford Tags: Business/Financial News Diabetes Diagnostics Mergers & Acquisitions Nipro Sinocare Source Type: news

Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging
; Mickael Tanter Non-invasive imaging deep into organs at microscopic scales remains an open quest in biomedical imaging. Although optical microscopy is still limited to surface imaging owing to optical wave diffusion and fast decorrelation in tissue, revolutionary approaches such as fluorescence photo-activated localization microscopy led to a striking increase in resolution by more than an order of magnitude in the last decade. In contrast with optics, ultrasonic waves propagate deep into organs without losing their coherence and are much less affected by in vivo decorrelation processes. However, their resolution is...
Source: Nature - November 25, 2015 Category: Research Authors: Claudia ErricoJuliette PierreSophie PezetYann DesaillyZsolt LenkeiOlivier CoutureMickael Tanter Tags: Letter Source Type: research

Fungal Infections of the Central Nervous System
This article summarizes current knowledge on the epidemiology, clinical presentations, diagnosis, and management of selected fungal infections of the central nervous system (CNS). Key syndromes, differential diagnoses, and therapeutic interventions according to host immune status and exposure are reviewed. Recent Findings:: Advancements in imaging of the brain and spinal cord, and molecular DNA and antigen-based laboratory diagnostics afford improved sensitivity for CNS mycoses. Newer therapeutic strategies may improve outcomes if provided early and host immunosuppression is abrogated. Adjunctive corticosteroid use for dis...
Source: CONTINUUM - December 1, 2015 Category: Neurology Tags: Review Articles Source Type: research

Regenerative firm Creative Medical launches cardio-focused AngioStem biz
Regenerative biotech company Creative Medical Health said today it is launching a subsidiary biz, AngioStem, to commercialize its cardiovascular assets. Assets on hand for the newly launched company include a therapy that uses autologous and allogeneic adult stem cells in combination with modulation of oxidative stress to treat heart failure in patients with cardiovascular disease, Creative Medical Health said. “At Creative Medical Health, our mission is to identify promising technologies, add value by strengthening the science and intellectual property surrounding the technologies, and subsequently spin off new com...
Source: Mass Device - February 29, 2016 Category: Medical Equipment Authors: Fink Densford Tags: Business/Financial News Cardiovascular Regenerative Medicine AngioStem Creative Medical Health Source Type: news

Corvia Medical wins FDA nod for trial, inks exclusive buyout deal with strategic backer
Corvia Medical said today that it won an investigational device exemption from the FDA for a clinical trial of its cardiac implant designed to treat diastolic heart failure and inked a deal with an unnamed strategic investor that includes an exclusive buyout option. Corvia’s transcatheter InterAtrial shunt device is designed to lower blood pressure in the left atrium and lungs by creating a small opening between the left and right atria, according to Corvia’s website. Tewksbury, Mass.-based Corvia said the 100-patient Reduce Lap-HF I study is a prospective, multicenter, randomized controlled trial. The primary ...
Source: Mass Device - March 7, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Cardiac Implants Cardiovascular Clinical Trials Mergers & Acquisitions Corvia Medical Source Type: news

Optimal Acquisition Settings for Speckle Tracking Echocardiography–Derived Strains in Infants: An In Vitro Study
The purpose of this study was to investigate the effect of frame rate and probe frequency on the accuracy of speckle tracking echocardiography–derived strain measurements in infants. An infant-sized left ventricle phantom with sonomicrometer crystals was made from polyvinyl alcohol. The examined stroke rates were 60, 120 and 180 strokes per min (SPM). Longitudinal strain and circumferential strain measurements were analyzed from a total of 1860 cine loops. These cine loops were acquired using two pediatric probes of different frequencies at both fundamental and harmonic imaging modes.
Source: Ultrasound in Medicine and Biology - April 12, 2016 Category: Radiology Authors: Umael Khan, Johannes Just Hjertaas, Gottfried Greve, Knut Matre Tags: Original Contribution Source Type: research

The Proof is in the Pudding: Does tDCS Actually Deliver DC Stimulation?
Transcranial direct current stimulation (tDCS) is an increasingly used investigational modality for a variety of disease conditions worldwide, including stroke.1 It is relatively easy-use, low-cost, and has a reasonable safety profile with currents up to 2 mA. The effect of tDCS on membrane potentials has been demonstrated in vitro2 as well as in vivo through simulation of tDCS-generated electric fields.3 Real-time monitoring of applied voltage and injected current in tDCS application is offered as an inbuilt feature of many tDCS devices and can be achieved with a simple data acquisition setup.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 10, 2016 Category: Neurology Authors: Pratik Y. Chhatbar, James R. Sawers, Wuwei Feng Source Type: research

A Flexible and Integrated System for the Remote Acquisition of Neuropsychological Data in Stroke Research
Telemedicine and e-Health , Vol. 0, No. 0.
Source: Telemedicine and e-Health - May 22, 2016 Category: Information Technology Authors: Corrine DuriskoMichael McCuePatrick J. DoyleMichael Walsh DickeyJulie A. Fiez Source Type: research