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Total 119 results found since Jan 2013.

Operational applications drive AI adoption in radiology
When talking about artificial intelligence (AI) in radiology, one immediately...Read more on AuntMinnie.comRelated Reading: AI predicts final infarct lesion for stroke on MRI New credentialing body formed for AI FDA recognizes AI-based image acquisition software AI may help improve management of stroke patients AI finds infarction in stroke patients on unenhanced CT
Source: AuntMinnie.com Headlines - March 17, 2020 Category: Radiology Source Type: news

Case report: Flow changes in routes of collateral circulation in patients with LVO and low NIHSS: a point favor to treat
In this study, we present the case of a 62-year-old individual, with left internal carotid occlusion stroke and low NIHSS, who had compensatory collateral flow from Willis polygon via the anterior communicating artery. The patient subsequently exhibited neurological deterioration and collateral flow failure from Willis polygon, indicating the need for urgent intervention. The study of collaterals in patients with large vessel occlusion stroke has garnered considerable attention, with research suggesting that individuals with low NIHSS scores and poor collateral profiles may be at a heightened risk of early neurological det...
Source: Frontiers in Neurology - June 8, 2023 Category: Neurology Source Type: research

Dynamic Iterative Reconstruction for Interventional 4-D C-Arm CT Perfusion Imaging
We present a dynamic, iterative reconstruction (DIR) approach to reconstruct TACs described by a weighted sum of basis functions. To reduce noise, a regularization technique based on joint bilateral filtering (JBF) is introduced. We evaluated the algorithm with a digital dynamic brain phantom and with data from six canine stroke models. With our dynamic approach, we achieve an average Pearson correlation (PC) of the PCCT canine blood flow maps to co-registered perfusion CT maps of 0.73. This PC is just as high as the PC achieved in a recent PCCT study, which required repeated injections and acquisitions.
Source: IEE Transactions on Medical Imaging - June 28, 2013 Category: Biomedical Engineering Source Type: research

A Fast Parallel Solver for the Forward Problem in Electrical Impedance Tomography
Electrical impedance tomography (EIT) is a noninvasive imaging modality, where imperceptible currents are applied to the skin and the resulting surface voltages are measured. It has the potential to distinguish between ischaemic and haemorrhagic stroke with a portable and inexpensive device. The image reconstruction relies on an accurate forward model of the experimental setup. Because of the relatively small signal in stroke EIT, the finite-element modeling requires meshes of more than 10 million elements. To study the requirements in the forward modeling in EIT and also to reduce the time for experimental image acquisiti...
Source: IEEE Transactions on Biomedical Engineering - December 19, 2014 Category: Biomedical Engineering Source Type: research

MassDevice.com +5 | The top 5 medtech stories for November 14, 2016
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Final FDA rules clarify adverse event reporting for contract manufacturers The FDA last week issued final guidance for medical device companies on the requirements for reporting adverse events that walked back much of the burde...
Source: Mass Device - November 14, 2016 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 5 Source Type: news

MassDevice.com +5 | The top 5 medtech stories for May 12, 2017
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Xtant Medical amends Orbimed credit line to $15m, taps restructuring advisors Xtant Medical said today that it amended its senior credit line with OrbiMed Advisors, saying it plans to use the $15 million facility to pay off the ...
Source: Mass Device - May 12, 2017 Category: Medical Devices Authors: MassDevice Tags: News Well Plus 5 Source Type: news

Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats
Publication date: Available online 21 September 2017 Source:Pharmacology Biochemistry and Behavior Author(s): Jens Bak Sommer, Anders Bach, Hana Malá, Kristian Strømgaard, Jesper Mogensen, Darryl S. Pickering Pharmacological inhibition of PSD-95 is a promising therapeutic strategy in the treatment of stroke, and positive effects of monomeric and dimeric PSD-95 inhibitors have been reported in numerous studies. However, whether therapeutic effects will generalize to other types of acute brain injury such as traumatic brain injury (TBI), which has pathophysiological mechanisms in common with stroke, is currently uncertain...
Source: Pharmacology Biochemistry and Behavior - September 22, 2017 Category: Biochemistry Source Type: research

Clinical applications of diffusion weighted imaging in neuroradiology
AbstractDiffusion-weighted imaging (DWI) has revolutionised stroke imaging since its introduction in the mid-1980s, and it has also become a pillar of current neuroimaging. Diffusion abnormalities represent alterations in the random movement of water molecules in tissues, revealing their microarchitecture, and occur in many neurological conditions. DWI provides useful information, increasing the sensitivity of MRI as a diagnostic tool, narrowing the differential diagnosis, providing prognostic information, aiding in treatment planning and evaluating response to treatment. Recently, there have been several technical improve...
Source: Insights into Imaging - May 30, 2018 Category: Radiology Source Type: research

Boston Scientific closes $270m Claret Medical buy
Boston Scientific (NYSE:BSX) said yesterday that it closed the $270 million buyout of Claret Medical and its Sentinel device, including a $50 million earnout pegged to a reimbursement win that just came in. Claret’s Sentinel device is designed to trap and remove debris dislodged during transcatheter aortic valve replacements to prevent stroke and other neurological damage. The deal, announced July 20, originally called for an up-front cash payment of $220 million plus the $50 million reimbursement milestone. That milestone was reached when the Centers for Medicare & Medicaid Services granted a New Technology Add...
Source: Mass Device - August 3, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Mergers & Acquisitions Replacement Heart Valves Wall Street Beat Boston Scientific Claret Medical Inc. Source Type: news

Medtronic to pay $51m to settle Covidien, ev3 DoJ investigations
Medtronic (NYSE:MDT) said yesterday that it agreed to pay $50.9 million to settle a number of U.S. Dept. of Justice probes into marketing activities from companies it acquired, Covidien and ev3. Medtronic said that its subsidiary ev3, acquired when the Fridley, Minn.-based medtech giant picked up Covidien in 2015, agreed to plead guilty to a misdemeanor charge related to its marketing of the Onyx Liquid Embolic System, pay $17.9 million and adopt new compliance and reporting terms for three years. The charges relate to ev3’s marketing of the device for “unproven and potentially dangerous uses,” federal prose...
Source: Mass Device - December 5, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Featured Legal News Medtronic Source Type: news

IschemaView launches Rapid Angio neuroimaging system
Medical imaging dev IschemaView said yesterday that it launched its Rapid Angio neuroimaging system designed for use in the angiography suite. The Menlo Park, Calif.-based company said that it partnered with Siemens (NYSE:SI) to integrate the Rapid software with Siemens’ SyngoDynaCT multiphase system for the newly launched imaging solution. Siemens’ SyngoDyna CT Multiphase is a 3D image acquisition technique which uses multiple rotations of a C-arm system to acquire multi-phasic 3D representation of the brain and its perfusion. “The Rapid Angio module, by combining the best-in-class syngoDynaCT system...
Source: Mass Device - March 1, 2019 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Imaging Neurological ischemaview Source Type: news

BCI-FES With Multimodal Feedback for Motor Recovery Poststroke
In this report, we describe device parameters and intervention protocols of our BCI-FES system which, combined with standard physical rehabilitation approaches, has proven efficacious in treating UE motor impairment in stroke survivors, regardless of level of impairment and chronicity.
Source: Frontiers in Human Neuroscience - July 6, 2022 Category: Neuroscience Source Type: research

Sensors, Vol. 23, Pages 6150: A Rigorous and Integrated On-Water Monitoring System for Performance and Technique Improvement in Rowing
oulis This paper presents a prototype, on-water rowing monitoring system and its testing results for a single scull boat. The proposed system aims at recording critical kinetic (athlete biomechanics and oar/seat movements) and kinematic (boat position, velocity, acceleration, and attitude) parameters for sport performance evaluation and rowing technique improvement. The data acquisition unit is organized in two parts: the first part aims at logging boat kinematics based on GNSS/INS filtering, while the second one facilitates kinetics data recording using a series of analog sensors (potentiometers, strain gauges) instal...
Source: Sensors - July 4, 2023 Category: Biotechnology Authors: Thanassis Mpimis Vassilis Gikas Vassilios Gourgoulis Tags: Article Source Type: research

With a broken promise, the government has handed the NHS over to the market | Clive Peedell
Reassurances on clinicians and local people controlling how services are commissioned look likely to be overturnedThe NHS needs to be reformed to remain true to its founding principles; the question is how. International evidence suggests that increasing marketisation and privatisation of healthcare services leads to greater expenditure, greater variations in care, reduced access to services, and erosion of professional standards. On that basis, the reforms have been heading in the wrong direction for a long time, with all the major political parties supporting policies that increase the role of the private sector in the N...
Source: Guardian Unlimited Science - March 3, 2013 Category: Science Authors: Clive Peedell Tags: Comment The Guardian Society Politics Privatisation NHS Andrew Lansley Comment is free Source Type: news

Storage of a naturally acquired conditioned response is impaired in patients with cerebellar degeneration
Previous findings suggested that the human cerebellum is involved in the acquisition but not the long-term storage of motor associations. The finding of preserved retention in cerebellar patients was fundamentally different from animal studies which show that both acquisition and retention depends on the integrity of the cerebellum. The present study investigated whether retention had been preserved because critical regions of the cerebellum were spared. Visual threat eye-blink responses, that is, the anticipatory closure of the eyes to visual threats, have previously been found to be naturally acquired conditioned respons...
Source: Brain - June 25, 2013 Category: Neurology Authors: Thieme, A., Thurling, M., Galuba, J., Burciu, R. G., Goricke, S., Beck, A., Aurich, V., Wondzinski, E., Siebler, M., Gerwig, M., Bracha, V., Timmann, D. Tags: Original Articles Source Type: research