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Infectious Disease: Gastroenteritis

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Total 109 results found since Jan 2013.

Engineering, expression and purification of a chimeric fibrin-specific streptokinase
Publication date: Available online 3 August 2016 Source:Protein Expression and Purification Author(s): Mohammad Naser Taheri, Abbas Behzad-Behbahani, Gholamreza Rafiei Dehbidi, Saeede Salehi, Sedigheh Sharifzadeh Streptokinase is a valuable fibrinolytic agent used to cope with myocardial infarction and brain stroke. Despite its high efficiency in dissolving blood clots, streptokinase (SK) has no specificity in binding fibrin, causing some problems such as internal bleedings following its administration. To make streptokinase fibrin specific and limit the fibrinolytic process to the clot location, we engineered a chimeric ...
Source: Protein Expression and Purification - August 2, 2016 Category: Biochemistry Source Type: research

In the Raw: To Cook or Not to Cook?
Imagine never again savoring the smell of baking cakes or charbroiled steak. Could you? Why would you? Yet some people worldwide are turning away not only from meat and processed food, but also from cooking. Welcome to the raw food diet. As the Standard American Diet becomes more fat-laden, sugar-sated, and processed, the prevalence of metabolic disorders, obesity, type 2 diabetes, and cardiovascular disease (CVD) are soaring. According to the Centers for Disease Control and Prevention (CDC), obesity now affects nearly 35 percent of the population of the United States, over 29 million people have been diagnosed with t...
Source: Healthy Living - The Huffington Post - August 4, 2016 Category: Consumer Health News Source Type: news

Bagged salads 'pose salmonella risk,' say researchers
Conclusion This laboratory study principally demonstrates that salad leaf juice – released from salad leaves when they are damaged or broken – supports the growth of salmonella bacteria, even at fridge temperature. If leaves are contaminated with salmonella, this isn't removed by washing in water. The results don't show that all packaged salad leaves are contaminated with gut bacteria like salmonella. What they do show is that if the bags have been contaminated with gut bacteria, these bacteria will replicate, even in the fridge, and there's little you can do to remove them. The best thing to do is to throw the bag o...
Source: NHS News Feed - November 21, 2016 Category: Consumer Health News Tags: Food/diet Source Type: news

Distensibility index of the inferior vena cava in experimental acute respiratory distress syndrome
In conclusion, a dIVC threshold<25% was associated with positive response after volume expansion and could be used to titrate fluids in endotoxin-induced ARDS.
Source: Respiratory Physiology and Neurobiology - December 22, 2016 Category: Respiratory Medicine Source Type: research

Chemical composition and antioxidant activities of essential oils from different parts of the oregano.
Abstract This research was undertaken in order to characterize the chemical compositions and evaluate the antioxidant activities of essential oils obtained from different parts of the Origanum vulgare L. It is a medicinal plant used in traditional Chinese medicine for the treatment of heat stroke, fever, vomiting, acute gastroenteritis, and respiratory disorders. The chemical compositions of the three essential oils from different parts of the oregano (leaves-flowers, stems, and roots) were identified by gas chromatography-mass spectrometry (GC-MS). The antioxidant activity of each essential oil was assessed using...
Source: J Zhejiang Univ Sci ... - December 31, 2016 Category: Science Authors: Han F, Ma GQ, Yang M, Yan L, Xiong W, Shu JC, Zhao ZD, Xu HL Tags: J Zhejiang Univ Sci B Source Type: research

SUMOylation of NaV1.2 channels mediates the early response to acute hypoxia in central neurons
The mechanism for the earliest response of central neurons to hypoxia —an increase in voltage-gated sodium current (INa) —has been unknown. Here, we show that hypoxia activates the Small Ubiquitin-like Modifier (SUMO) pathway in rat cerebellar granule neurons (CGN) and that SUMOylation of NaV1.2 channels increasesINa. The time-course for SUMOylation of single NaV1.2 channels at the cell surface and changes inINa coincide, and both are prevented by mutation of NaV1.2-Lys38 or application of a deSUMOylating enzyme. Within 40 s, hypoxia-induced linkage of SUMO1 to the channels is complete, shifting the voltage-dependence ...
Source: eLife - December 28, 2016 Category: Biomedical Science Tags: E. coli Human Human Biology and Medicine hypoxia ischemia Neuroscience Rat SCN2A stroke SUMO Source Type: research

Incidence of fatal snake bite in Australia: A coronial based retrospective study (2000-2016).
CONCLUSIONS: Death from snake bite remains rare in Australia, and has maintained a steady rate for over 20 years. Usually considered a 'rural issue', and with varying recorded causes of death, a nationally co-ordinated effort to further review the national picture of envenoming in Australia can inform education and resource needs within state and local contexts. PMID: 28288937 [PubMed - as supplied by publisher]
Source: Toxicon - March 9, 2017 Category: Toxicology Authors: Welton R, Liew D, Braitberg G Tags: Toxicon Source Type: research

Zika associated Guillain-Barre syndrome in the United States (P2.327)
Conclusions:Zika can induce GBS after a brief viral illness. Neuropathy can be a mixture of demyelinating and axonal. Dysautonomia may also be present including severe dysphagia, orthostatics and retention.Zika RNA has a short detection window in serum and CSF making a diagnosis time sensitive. Serological assays using IgM and IgG cross-react with other flaviviruses making them unable to differentiate between recent Zika exposure and cross reactivity with Dengue and Chikungunya. Our pt likely had prior exposure to Dengue, being from an endemic area. Prior Dengue exposure may possibly modulate the response to Zika via antib...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tantillo, G., Sclar, G., Vasa, C., Shin, S., Sivak, M. Tags: Zika, Chikungunya, West Nile Virus, and Other Viral Infections I Source Type: research

Added value of interleukin-1 blockade to hypothermia in neonatal encephalopathy due to inflammatory-sensitized hypoxia-ischemia: a preclinical study. (P3.212)
Conclusions:Our results demonstrate that IL-1Ra (50mg/kg) has an added value to the neuroprotective effect of HT in LPS+HI-induced NE. This project could open new therapeutic avenues to prevent CP.Study Supported by:CIHR, FRQ-S, Heart and Stroke Foundation, "Tranzyme-Pharma" scholarship fom Université de Sherbrooke, and Foundation of Stars.Disclosure: Dr. Chevin has nothing to disclose. Dr. Guiraut has nothing to disclose. Dr. Sebire has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Chevin, M., Guiraut, C., Sebire, G. Tags: Child Neurology I Source Type: research

Miller fisher syndrome presenting with prodromal thunderclap headache
Conclusions Although not radiographically confirmed, we postulate the headache may have been due to reversible cerebral vasoconstriction syndrome (RCVS), given the characteristics of the headache and dramatic response to nimodipine. Although headache is infrequently observed in Miller Fisher syndrome, the exact aetiology is unclear and there has been no previously reported association with RCVS.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 8, 2017 Category: Neurosurgery Authors: Waters, M. J., Kiley, M. Tags: Abstracts Source Type: research

MassDevice.com +5 | The top 5 medtech stories for July 25, 2017
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. How a single drop of blood can detect sepsis Sepsis can be identified by a single drop of blood, thanks to a lab-on-a-chip device from the University of Illinois. Researchers at the University of Illinois and the Carle Foundati...
Source: Mass Device - July 25, 2017 Category: Medical Devices Authors: MassDevice Tags: News Well Plus 5 Source Type: news

Aortic dissection in the thrombolysis era: Rare but potentially fatal cause of stroke
Fabio Pilato, Francesco Iodice, Marisa Distefano, Paolo Profice, Antonella Coli, Rosalinda CalandrelliNeurology India 2017 65(6):1395-1399
Source: Neurology India - November 10, 2017 Category: Neurology Authors: Fabio Pilato Francesco Iodice Marisa Distefano Paolo Profice Antonella Coli Rosalinda Calandrelli Source Type: research

Guillain-Barr é syndrome following varicella-zoster virus infection
We describe the frequency, clinical features, and electrophysiological and immunological phenotypes of Guillain-Barr é Syndrome (GBS) patients treated at a single institution in Bangladesh who had preceding chicken pox (primary Varicella-zoster virus [VZV] infection) within 4 weeks of GBS onset. A literature review of GBS cases preceding VZV infection is also provided. Diagnosis of GBS was based on the National Institute of Neurological Disorders and Stroke criteria for GBS. Serum anti-VZV IgM and IgG antibodies were quantified by indirect chemiluminescence immunoassay (CLIA); anti-Campylobacter jejuni IgG, IgM, and IgA ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - February 6, 2018 Category: Microbiology Source Type: research

Atypical hemolytic uremic syndrome and eculizumab therapy in children.
Authors: Kim SH, Kim HY, Kim SY Abstract Hemolytic uremic syndrome (HUS) is often encountered in children with acute kidney injury. Besides the well-known shiga toxin-producing Escherichia coli-associated HUS, atypical HUS (aHUS) caused by genetic complement dysregulation has been studied recently. aHUS is a rare, chronic, and devastating disorder that progressively damages systemic organs, resulting in stroke, end-stage renal disease, and death. The traditional treatment for aHUS is mainly plasmapheresis or plasma infusion; however, many children with aHUS will progress to chronic kidney disease despite plasma the...
Source: Korean Journal of Pediatrics - March 25, 2018 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

How are Malformations of the Cerebral Cortex Grouped?
Discussion Cerebral cortex development is an extremely complex process overall. Our current understanding is incomplete and constantly changing as our understanding of genetics and the processes each gene controls emerges from scientific research. Neural cells are produced in the subventicular zone of the pallial or dorsal germinal epithelium. They then differentiate and migrate radially or tangentially to the cerebral cortex and organize themselves to function. Malformations of cortical development (MCD) is a heterogeneneous group of disorders that cause defective cortical development. These disorders are broadly catego...
Source: PediatricEducation.org - July 23, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news