Food allergy and food-induced anaphylaxis in children: an increasing critical public health issue.
Authors: Lee S PMID: 31870083 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - December 26, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Reconsideration of urine culture for the diagnosis of acute pyelonephritis in children: a new challenging method for diagnosing acute pyelonephritis.
Authors: Lee JH, Rhie S Abstract Acute pyelonephritis (APN) should be detected and treated as soon as possible to reduce the risk of the development of acquired renal scarring. However, in the medical field, urine culture results are not available or considered when the prompt discrimination of APN is necessary and empirical treatment is started. Furthermore, urine culture cannot discriminate APN among children with febrile urinary tract infection (UTI) (pyelitis, lower UTI with other fever focus). Therefore, the usefulness of urine culture for diagnostic purposes is small and the sampling procedure is invasive. Co...
Source: Korean Journal of Pediatrics - December 26, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Is there a simple and less invasive way to accurately diagnose acute pyelonephritis?
Authors: Kim SH PMID: 31870085 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - December 26, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Hypoxia-inducible factor: role in cell survival in superoxide dismutase overexpressing mice after neonatal hypoxia-ischemia.
CONCLUSION: HIF-1α and HIF-2α may promote cell survival in neonatal HI in a cell-specific and regional fashion. Our findings suggest that early HIF-2α upregulation precedes apoptotic cell death and limits necrotic cell death. However, the influence of SOD was not clarified; it remains an intriguing factor in neonatal HI. PMID: 31870086 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - December 26, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Lipid accumulation product is a predictor of nonalcoholic fatty liver disease in childhood obesity.
Authors: Özcab─▒ B, Demirhan S, Akyol M, Öztürkmen Akay H, Güven A Abstract BACKGROUND: Lipid accumulation product (LAP) is associated with the presence and severity of nonalcoholic fatty liver disease (NAFLD) in adults. PURPOSE: Here we evaluated the ability of LAP to predict NAFLD in obese children. METHODS: Eighty obese children (38 girls; age 6-18 years) were included. Anthropometric measurements and biochemical values were obtained from the patients' medical records. LAP was calculated as [waist circumference (WC) (cm) - 58]×triglycerides (mmol/L) in girls; [WC (cm) - 65]&time...
Source: Korean Journal of Pediatrics - December 26, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review.
Authors: Jenabi E, Ataei S, Bashirian S Abstract A structured review study of drug interventions on sleep disorders in patients with autism spectrum disorders (ASD) has not been published to date. This systematic review aimed to investigate drug interventions for the treatment of sleep disorders in children with ASD. The Web of Science, PubMed, and Scopus databases were searched until March 2019. Study quality was assessed using the Delphi checklist. Due to the heterogeneity of the findings, a meta-analysis was not possible. Drug interventions for the treatment of sleep disorders in patients with ASD included melat...
Source: Korean Journal of Pediatrics - November 26, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Monitoring BK virus infection in pediatric kidney transplant recipients.
Authors: Cho MH PMID: 31760720 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - November 26, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Clinical manifestations of BK virus infection in pediatric kidney transplant patients.
CONCLUSION: BKV infection is common in children with kidney transplantation and might not have affected short-term renal function in our patient sample due to early immunosuppressant reduction at the time of BKV detection. PMID: 31760721 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - November 26, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Gray-brown skin discoloration following phototherapy for hyperbilirubinemia due to anti-E alloimmunization.
Authors: Lee DJ, Song WS, Kim SY PMID: 31760722 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - November 26, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Strategies to improve outcomes of bronchopulmonary dysplasia.
Authors: Jung YH, Choi CW, Kim BI PMID: 31623418 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 20, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Can proton pump inhibitors cause intestinal inflammation in children?
Authors: Kang B PMID: 31623419 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - October 20, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Assessment of interhospital transport care in pediatric patients.
Conclusion: We report an incidence of adverse events occurring during transport of critical ill pediatric patient of 22%. Most of the events were physiologic deterioration. The escort personal maybe the key person to prevent and appropriately monitor any complication during the transport. PMID: 31477679 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - September 4, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Genetic classification and confirmation of inherited platelet disorders and current status in Korea.
Authors: Shim YJ Abstract Inherited platelet disorders (IPDs), which manifest as primary hemostasis defects, often underlie abnormal bleeding and a family history of thrombocytopenia, bone marrow failure, hematologic malignancies, undefined mucocutaneous bleeding disorder, or congenital bony defects. A wide heterogeneity in IPD types, in regard to the presence or absence of thrombocytopenia, platelet dysfunction, bone marrow failure, and dysmegakaryopoiesis, is observed in patients. The individual processes involved in platelet production and hemostasis are genetically controlled: to date, mutations more than 50 ge...
Source: Korean Journal of Pediatrics - September 4, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Placental Histopathology in Late Preterm infants: Clinical Implications.
Authors: Ericksen K, Fogel J, Verma RP Abstract Background: The etiopathogenesis of late preterm birth is undetermined. Placental histopathology (PH) reflects adverse intrauterine environment and is documented to be associated with preterm labor and neonatal morbidities. The placental histopathology has not been studied in late preterm infants. Purpose: We investigated placental pathological lesion as markers of adverse intrauterine environment during late preterm labor. Methods: In a retrospective case control study following placental histopathological and clinical variables were compared between late pre...
Source: Korean Journal of Pediatrics - August 23, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Autoimmune Encephalitis and Epilepsy: Evolving Definition and Clinical Spectrum.
Authors: Seo JH, Lee YJ, Lee KH, Gireesh E, Skinner H, Westerveld M Abstract Advances in autoimmune encephalitis studies in the past 10 years have headed to the identification of new syndromes and biomarkers that have transformed the diagnostic approach to the disorder. The disorder or syndrome has been linked to a wide variety of pathologic processes associated with the neural-specific autoantibodies targeting both intracellular and plasma membrane antigens. However, current criteria for autoimmune encephalitis are very dependent on antibody testing and response to immunotherapy, which might delay the diagnosis. T...
Source: Korean Journal of Pediatrics - August 23, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Practical considerations when administering surfactants to preterm infants with respiratory distress syndrome.
Authors: Jo HS PMID: 31431604 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - August 23, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Effectiveness and comparison of various Non-Pharmacological methods of analgesia in newborns.
Authors: Kumar P, Sharma R, Rathour S, Karol S, Karol M Abstract Background: Pain during the developmental period has potential to adversely affect developing neuronal pathways and cause adverse neurodevelopmental, cognitive and behavioural effects in later life. Immunization e.g. Hepatitis B vaccine (HBV) at birth is a painful experience to which neonates are subjected universally. Purpose: We aimed to study and compare the effectiveness of the various non-pharmacological method of pain management in newborns so that the safe and effective analgesic methods can be evolved in newborns. Methods: It was a pro...
Source: Korean Journal of Pediatrics - August 23, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Comparative validity of microalbuminuria with clinical mortality scores to predict outcome in paediatric intensive care unit.
Conclusion: Microalbuminuria is a good predictor of outcome in PICU and is comparable with Mortality scores. PMID: 31401824 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - August 14, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Association between Body Mass Index and Hepatitis B antibody seropositivity in children.
Authors: Kwon Y, Jeong SJ Abstract Background: The seropositivity rate of antibodies against hepatitis B surface antigen (anti-HBs) is known to be ≥95% after Hepatitis B virus (HBV) vaccination during infancy. However, low or absence of anti-HBs in healthy children are discovered in many cases. Recent, studies in adults have reported that reduction in the rate of anti-HBs production is related to obesity. Purpose: The present study investigated whether body mass index (BMI) affects anti-HBs level in healthy children following three serial dose vaccination in infancy. Methods: We recruited 1200 healthy vo...
Source: Korean Journal of Pediatrics - August 14, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Can the accurate epidemiological study help to search the etiology of Kawasaki disease?
Authors: Han JW PMID: 31401826 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - August 14, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Considerations for evaluating the effectiveness and long term outcome of enzyme replacement therapy in Pompe disease.
Authors: Cheon CK PMID: 31401827 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - August 14, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Central line-associated bloodstream infections in neonatal intensive care unit.
Authors: Lee WR PMID: 31319642 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Reality of the Kawasaki disease epidemiology.
Authors: Kim GB Abstract Epidemiologic studies of Kawasaki disease (KD) have shown new pattern or change of KD occurrence and supported to infer pathophysiology or risk factors of KD from the first patient with KD reported in 1961. The incidence of KD in Northeast Asia country including Japan, South Korea, China and Taiwan are 10-30 times higher than that of KD in the Unites States and Europe. Knowing true epidemiology of KD in each country and publications of update KD epidemiology also could give KD vigilance to general health care provider and general population, which definitely could give early detection of KD...
Source: Korean Journal of Pediatrics - July 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis.
Authors: Choi BS PMID: 31319644 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Eosinophil Count and Neutrophil-to-Lymphocyte Count Ratio as Biomarkers for Prediction of Early-onset Neonatal Sepsis.
Authors: Lee JH PMID: 31319645 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

The relation between genetic heterogeneity and variability for response to growth hormone in Noonan syndrome.
Authors: Shin YL PMID: 31319646 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Influence of proton pump inhibitor therapy on intestinal inflammation assessed by fecal calprotectin in pediatric patients.
Conclusion: We attempted to confirm the evidence of intestinal inflammation due to PPI use in children and adolescents through clinical symptoms and FC measurement; however, no significant changes were observed. PMID: 31319647 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Why we should be monitored the hematologic adverse drug reaction of oxcarbazepine?
Authors: Jang GC PMID: 31319648 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Endoscopic post-dilatation application of Mitomycin-C in children with resistant esophageal strictures.
Conclusion: Esophageal dilatation followed by local Mitomycin - C application may be a useful strategy in resistant esophageal strictures. PMID: 31319649 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Prevalence of hyperuricemia and its association with metabolic syndrome and cardiometabolic risk factors in Korean children and adolescents: based on the 2016-2017 Korea National Health and Nutrition Examination Survey.
Authors: Lee JH Abstract Purpose: The study aimed to investigate the prevalence of hyperuricemia and its association with metabolic syndrome (MetS) and cardiometabolic risk factors (CMRFs) in Korean children and adolescents. Methods: This cross-sectional survey used data from the 7th Korea National Health and Nutrition Examination Survey (2016-2017), and 1,256 males and females aged 10-18 years were included. Hyperuricemia was defined when SUA levels were>6.6 mg/dL at 10-11 years of age (both sex), and>7.7 mg/dL for males at 12-18 years of age and>5.7 mg/dL for females at 12-18 years of age. MetS was d...
Source: Korean Journal of Pediatrics - July 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Controversies in the diagnosis and treatment of hemodynamically significant patent ductus arteriosus in preterm infants.
Authors: Sung SI PMID: 31319651 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - July 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Corrigendum: Cardiac function associated with home ventilator care in Duchenne muscular dystrophy.
Authors: Lee S, Lee H, Eun LY, Gang SW Abstract PMID: 31208158 [PubMed - in process] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - June 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

The maternal pre-pregnancy BMI and the risk of ADHD among children and adolescents: A systematic review and meta-Analysis.
Authors: Jenabi E, Bashirian S, Khazaei S, Basiri Z Abstract This meta-analysis evaluated the association between maternal pre-pregnancy body mass index (BMI) and the risk of attention deficit hyperactivity disorder (ADHD) among children and adolescents. The search strategy was conducted until December 2018 in databases of PubMed, Web of Science and Scopus. The ORs or HRs with 95% confidence intervals (CI) extracted from eligible studies used as the common measure of association among studies. A significant association was found between overweight women and risk of ADHD among children with the pooled estimates of H...
Source: Korean Journal of Pediatrics - June 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Can iron be a risk factor for coronary lesion in Kawasaki disease?
Authors: Yoon KL PMID: 31208167 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - June 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Recommended Immunization Schedule for Children and Adolescents: Committee on Infectious Diseases of the Korean Pediatric Society, 2018.
This report provides the revised recommendations made by the committee and summarizes several changes from the 2015 guideline. National immunization program (NIP) launched a human papillomavirus (HPV) immunization for girls aged 12 years in 2016. NIP has also expanded age indication for inactivated influenza vaccine (IIV) to 12 years of age in the 2018-2019 season. Quadrivalent IIVs with a full dose (0.5 mL) are approved for all children of 6 months or older. Recommendations of live attenuated influenza vaccine were removed. For inactivated Japanese encephalitis vaccine (JEV), first two doses are considered as the primary ...
Source: Korean Journal of Pediatrics - June 7, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Clinical impact of admission hypothermia in very low birth weight infants: Results from Korean neonatal network.
Authors: Lee NH, Nam SK, Lee J, Jun YH Abstract Background: Preterm infants have difficulty maintaining body temperature after birth. However, clinical guidelines advocate that neonatal body temperature should be maintained at 36.5-37.5°C. Purpose: We aimed to investigate the incidence of admission hypothermia in very low birth weight (VLBW) infants and to determine the association of admission temperature with in-hospital mortality and morbidities. Methods: A cohort study using prospectively collected data involving 70 neonatal intensive care units (NICUs) that participate in the Korean neonatal networ...
Source: Korean Journal of Pediatrics - May 29, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

On the effect of omega-3 supplementation with methylphenidate as an alternative therapy to reduce Attention Deficit Hyperactivity Disorder (ADHD) in children.
Conclusion: The results of our study showed that a specific dose of omega-3 for eight weeks had no effect on the treatment of ADHD. PMID: 31122010 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 29, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Bronchopulmonary dysplasia; what should we do to improve its outcomes?
Authors: Sung TJ Abstract Bronchopulmonary dysplasia (BPD) is a chronic lung disease of preterm infants with multiple factors affected from prenatal to postnatal periods. Despite the great advances in neonatal care over almost 50 years, the rates of BPD are not decreased and may even have risen. Since more preterm infants even in periviable gestational age are survived nowadays, different stages of lung development have an effect on the pathogenesis of BPD. Hence the definition of BPD had been changed from 'old' BPD and 'new' BPD. In this review, the various definition of BPD, risk factors from prenatal to postnata...
Source: Korean Journal of Pediatrics - May 29, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

The role of Lactobacillus reuteri DSM 17938 for the absorption of iron preparations in children with iron deficiency anemia.
Authors: Manoppo J, Tasiringan H, Wahani A, Umboh A, Mantik M Abstract PURPOSE: To determine whether Lactobacillus reuteri DSM 17938 plays a role in absorption of iron preparations given to children with iron deficiency anemia (IDA). METHODS: We performed a quasi-experimental study involving pre- and postintervention tests using a control group in North Sulawesi province, Indonesia, between July and September 2017. We conducted a single-blind controlled trial that included primary school children who were diagnosed with IDA based on reticulocyte hemoglobin equivalent (Ret-He) levels
Source: Korean Journal of Pediatrics - May 22, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

To give or not to give partially hydrolyzed infant formula to general population for primary prevention?
Authors: Song TW PMID: 31096738 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Understanding the importance of cerebrovascular involvement in Kawasaki disease.
Authors: Yeom JS, Cho JY, Woo HO Abstract Kawasaki disease (KD) is a systemic vasculitis in infants and young children. The natural history of KD has not been fully elucidated because the first case of KD was reported in late 1960s and patients who have recovered will just now entering middle age. Nevertheless, several evidences have raised concerns regarding the subclinical vascular changes in post-KD patients. KD have focused on the coronary artery aneurysms because which are directly associated with fatality. However, aneurysms have been reported in other extra-cardiac muscular arteries and their fate seems to r...
Source: Korean Journal of Pediatrics - May 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Correlation Of Serum S100B Levels With MRI Abnormalities In Children With Status Epilepticus.
Authors: Gunawan PI, Saharso D, Sari DP Abstract Purpose: To evaluate the association of elevated S100B levels with brain tissue damage seen in abnormalities of head MRI (Diffusiion-Tensor Imaging (DTI) sequence) in patients with Status Epilepticus. Methods: an analytical observational study was conducted in children hospitalized at Dr Soetomo hospital, Surabaya from July 2016 to December 2016. The patients were divided into two groups. The SE groups consisted of all children with a history of SE and the control group consisted of all children with febrile seizure. Blood samples of patients were drawn within 24...
Source: Korean Journal of Pediatrics - May 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Importance of Coronary Artery Dominance in children to determined coronary artery dilatation.
Authors: Choi HJ PMID: 31096741 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Is there any specific infection that causes Kawasaki disease?
Authors: Lee DS PMID: 31096742 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis.
Authors: Choi Y, Jeon H, Yang EA, Yoon JS, Kim HH Abstract Background: Researcher showed that EPO is a relatively accurate marker of eosinophilia and eosinophil activity and that EPO has a higher correlation to them. However, it's use as markers of eosinophilic inflammation in nasal secretions is limited because the diagnostic cut-off values of EPO for use as one-time tests for allergic diseases such as allergic rhinitis have not been established. Purpose: To identify the correlation between nasal eosinophil and eosinophil peroxidase (EPO) in children and adolescents with rhinitis. Methods: We recruited pat...
Source: Korean Journal of Pediatrics - May 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Prevalence of Obesity and Overweight in Iranian Children under 5 Years: A Systematic Review and Meta-analysis.
Conclusion: Although, there was a high heterogeneity among the results of the articles included in the meta-analysis, however, the prevalence of obesity and overweigh is higher in Iranian children under 5 years. Therefore, parents and the health system need to pay more attention to lifestyle, nutritional habits and physical activity of these children. PMID: 31096744 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - May 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Phenotypes of allergic diseases in children and their application in clinical situations.
Authors: Lee E, Hong SJ Abstract Allergic disease, including allergic rhinitis, asthma, and atopic dermatitis, are huge heterogeneous diseases, encompassing diverse phenotypes with different pathogenesis. Phenotype studies on allergic diseases are important in that they can facilitate the identification of risk factors and the underlying pathophysiologies, resulting in the application of more effective treatment, selection of better response to the treatment, and prediction of prognosis for each phenotype. In the early phase of phenotype studies in allergic diseases, artificial classifications were usually performe...
Source: Korean Journal of Pediatrics - May 19, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Predictors and management of intravenous immunoglobulin-resistant Kawasaki disease.
Authors: Song MS Abstract Kawasaki disease (KD) is a systemic vasculitis that mainly affects younger children. Intravenous immunoglobulin (IVIG) resistant cases are at increasing risk for coronary artery complications. The strategy on prediction of potential nonresponders and treatment of IVIG-resistant patients is now controversial. In this review the definition and predictors of IVIG-resistant KD and current evidence to guide management are discussed. PMID: 30999718 [PubMed] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - April 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

Evaluation of hematologic profile may be needed for patients treated with oxcarbazepine.
Authors: Jung GH, You SJ Abstract Purpose: The major side effects of treatment with oxcarbazepine (OXC) are skin rash and hyponatremia. Hematologic side effects are reported to be rare. The aim of this study was to investigate the rate and types of hematologic side effects of OXC. Methods: The medical records of 184 patients who were diagnosed with epilepsy or movement disorder and treated with OXC monotherapy at the Department of Pediatrics of Sanggye Paik Hospital from July 2001 to July 2018 were retrospectively reviewed. Results: Of the 184 patients, 10 (5.4%) developed leukopenia including pancytopenia ...
Source: Korean Journal of Pediatrics - April 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research

The Association of vitamin D status at birth and respiratory outcomes in preterm infants.
Authors: Park SH PMID: 30999725 [PubMed - as supplied by publisher] (Source: Korean Journal of Pediatrics)
Source: Korean Journal of Pediatrics - April 21, 2019 Category: Pediatrics Tags: Korean J Pediatr Source Type: research