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Total 234 results found since Jan 2013.

Mechanical thrombectomy is efficacious in patients with pre ‐stroke moderate disability
ConclusionPatients with pre-stroke moderate disability may benefit from MT if they are appropriately selected. This may result in fewer patients requiring nursing home placement and less financial burden on the public health system, indicating significant savings are possible.
Source: Journal of Medical Imaging and Radiation Oncology - June 17, 2021 Category: Radiology Authors: Tara Nababan, Timothy J. Phillips, Graeme J. Hankey, Matthew T. Crockett, Albert Ho Yuen Chiu, Tejinder P. Singh, David Blacker, William McAuliffe Tags: Medical Imaging —Original Article Source Type: research

Atrial fibrillation in young stroke patients: do we underestimate its prevalence?
ConclusionAF may be more common than expected in young patients with IS and is associated with increased NIHSS scores.
Source: European Journal of Neurology - May 17, 2013 Category: Neurology Authors: D. Prefasi, P. Martínez‐Sánchez, A. Rodríguez‐Sanz, B. Fuentes, D. Filgueiras‐Rama, G. Ruiz‐Ares, B. E. Sanz‐Cuesta, E. Díez‐Tejedor Tags: Original Article Source Type: research

Thrombolysis in patients with prior stroke within the last 3 months
ConclusionsIn patients with prior stroke within the last 3 months, none of the sICHs and only one asymptomatic intracerebral hemorrhage occurred in the region of the former infarct. The high mortality was influenced by four patients, who died until discharge due to acute major index stroke. It is reasonable to include these patients in randomized clinical trials and registries to assess further their thrombolysis benefit−risk ratio.
Source: European Journal of Neurology - July 17, 2014 Category: Neurology Authors: M. R. Heldner, H. P. Mattle, S. Jung, U. Fischer, J. Gralla, C. Zubler, M. El‐Koussy, G. Schroth, M. Arnold, M.‐L. Mono Tags: Original Article Source Type: research

Anemia in young patients with ischaemic stroke
ConclusionAnemia on admission was associated with stroke in CeAD patients and with more severe strokes in both study samples. Moderate to severe anemia may predict unfavorable outcome.
Source: European Journal of Neurology - February 24, 2015 Category: Neurology Authors: L. Kellert, M. Kloss, A. Pezzini, T. M. Metso, A. J. Metso, S. Debette, D. Leys, V. Caso, V. Thijs, A. Bersano, E. Touzé, T. Tatlisumak, H. Gensicke, P. A. Lyrer, J. Bösel, S. T. Engelter, C. Grond‐Ginsbach, Tags: Original Article Source Type: research

Post‐stroke cognitive impairment is common even after successful clinical recovery
ConclusionsCognitive impairment as evaluated with a comprehensive neuropsychological assessment is prevalent in stroke survivors even with successful clinical recovery. Typically multiple domains and complex cognitive abilities are affected. MMSE is not sensitive in detecting these symptoms. Post‐stroke cognitive impairment is strongly related to poor functional outcome.
Source: European Journal of Neurology - June 4, 2015 Category: Neurology Authors: H. Jokinen, S. Melkas, R. Ylikoski, T. Pohjasvaara, M. Kaste, T. Erkinjuntti, M. Hietanen Tags: Original Article Source Type: research

Influence of previous physical activity on the outcome of patients treated by thrombolytic therapy for stroke
Abstract Physical activity prevents stroke and is associated with less severe strokes. The neuroprotective effect in patients treated with intravenous (i.v.) recombinant tissue plasminogen activator (rt-PA), remains uncertain. We aimed at evaluating the relationship between previous physical activity and outcomes in stroke patients treated with i.v. rt-PA. OPHELIE-SPORT was a prospective observational multicenter study conducted in French and Japanese stroke patients treated with i.v. rt-PA. We evaluated the presence, weekly duration (<2, 2–5, >5 h) and intensity (light, moderate, heavy) of previous leisu...
Source: Journal of Neurology - August 14, 2015 Category: Neurology Source Type: research

Increase in Neutrophil after r ‐tPA Thrombolysis Predicts Poor Functional Outcome of Ischemic Stroke: A Longitudinal Study
ConclusionsDynamic increase in neutrophil after stroke significantly predicts 3‐month death or major disability in acute ischemic stroke patients receiving r‐tPA treatment.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - January 1, 2018 Category: Neurology Authors: Jijun Shi, Hao Peng, Shoujiang You, Yuanyuan Liu, Jiaping Xu, Yingying Xu, Huihui Liu, Rongfang Shi, Yongjun Cao, Chun ‐Feng Liu Tags: Original Article Source Type: research

Sex as predictor for achieved health outcomes and received care in ischemic stroke and intracerebral hemorrhage: a register-based study
ConclusionsA lower proportion of women had good functioning, a difference that remained in IS after adjustments for age, socioeconomic factors, living arrangements, ADL dependency, and stroke severity. The amount of received hospital care was lower for women after adjustments. Whether shorter hospital stay results in lower function or is a consequence of lower function cannot be elucidated. One-year survival was higher in men when no adjustments were made but lower after adjustments. This likely reflects that women were older at time of stroke, had more severe strokes, and more disability pre-stroke —factors that make a ...
Source: Biology of Sex Differences - March 7, 2018 Category: Biology Source Type: research

Early apixaban therapy after ischemic stroke in patients with atrial fibrillation
ConclusionsSymptomatic HT rates are likely to be low in randomized trials of DOAC initiation post-stroke. Recurrent ischemic stroke may be the major clinical outcome. These data may be used as expected event rates when calculating sample size requirements for future safety/efficacy trials of early versus late DOAC initiation after AF-related stroke.
Source: Journal of Neurology - January 3, 2021 Category: Neurology Source Type: research

The value of the use of plasma B-type natriuretic peptide among acute ischemic stroke patients in a Chinese emergency department
In this study, 142 of 238 acute ischemic stroke patients met the study criteria [mean age 70.84±11.48 years, 74 (52.11%) female]. Of the 142 patients, 35.92% were diagnosed with LAA at discharge, 25.35% with CE, 27.46% with SAO, 11.27% with SOE or SUE. Age, previous cardiac disease, atrial fibrillation, the length of hospital stays, SSS score on admission≤25 and mRS≥3 or death at discharge were all significantly higher in the CE patients compared to other subtypes (p
Source: Clinical Neurology and Neurosurgery - March 21, 2013 Category: Neurosurgery Authors: Wu Zhixin, Yang Lianhong, Huang Wei, Li Lianda, Jiang Longyuan, Zhang Yingjian, Wang Jinliang, He Mingfeng Tags: Original articles Source Type: research

Transfer of stroke patients impairs eligibility for endovascular stroke treatment
Conclusions EST should be provided directly whenever possible as one in four transferred stroke patients becomes ineligible for EST during transfer. If direct transfer is not possible, indication for EST should be re-assessed after transfer.
Source: Journal of Neuroradiology - September 19, 2017 Category: Radiology Source Type: research

Direct Admission vs. Secondary Transfer to a  Comprehensive Stroke Center for Thrombectomy
ConclusionThese results confirm prior studies stating that DA to a  comprehensive stroke center leads to better outcome compared to ST in stroke patients undergoing thrombectomy.
Source: Klinische Neuroradiologie - October 10, 2019 Category: Radiology Source Type: research

Untargeted metabolomics predicts the functional outcome of ischemic stroke.
CONCLUSION: Metabolomics is a potential method to explore the blood biomarkers of acute ischemic stroke. The patients with unfavorable outcomes had a lower PAF level compared to those with favorable outcomes. PMID: 32414667 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - May 12, 2020 Category: General Medicine Authors: Chi NF, Chang TH, Lee CY, Wu YW, Shen TA, Chan L, Chen YR, Chiou HY, Hsu CY, Hu CJ Tags: J Formos Med Assoc Source Type: research

Early rehabilitation after stroke: relationship between the heart rate variability and functional outcome
ConclusionsThe presence of autonomic cardiovascular dysregulation in patients with subacute stroke was associated with adverse functional outcome after the early post ‐stroke rehabilitation.
Source: ESC Heart Failure - July 29, 2020 Category: Cardiology Authors: Nadja Scherbakov, Anush Barkhudaryan, Nicole Ebner, Stephan Haehling, Stefan D. Anker, Michael Joebges, Wolfram Doehner Tags: Original Research Article Source Type: research