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Infectious Disease: Superbugs

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Total 234 results found since Jan 2013.

Preexisting cognitive impairment in intracerebral hemorrhage
ConclusionsIn conclusion, cognitive impairment frequently precedes ICH. A higher frequency of cerebrovascular events suggests a role of vascular processes in the development of cognitive impairment before ICH.
Source: Acta Neurologica Scandinavica - August 9, 2016 Category: Neurology Authors: M. Laible, S. Horstmann, M. M öhlenbruch, S. Schueler, T. Rizos, R. Veltkamp Tags: Original Article Source Type: research

Clinical Issues —September 2017
Performing Staphylococcus aureus decolonization for urgent proceduresKey words: decolonization, Staphylococcus aureus, MRSA, MSSA, mupirocin.Hand hygiene before donning glovesKey words: hand hygiene, glove, personal protective equipment.Hand hygiene before skin prepKey words: hand hygiene, skin prep, sterile task, aseptic task.Scrubbing by stroke versus timed methodKey words: surgical hand rub, surgical scrub, stroke method, timed method.
Source: AORN Journal - August 31, 2017 Category: Nursing Authors: Amber Wood Tags: Column Source Type: research

Decompressive hemicraniectomy for malignant middle cerebral artery infarction including patients with additional involvement of the anterior and/or posterior cerebral artery territory —outcome analysis and definition of prognostic factors
ConclusionsIntensified postoperative management including possible secondary decompression with necrosectomy may further reduce case fatality rate of patients with large hemispheric infarction. Age above 60  years and severely reduced level of consciousness are the most significant factors heralding unfavorable recovery. Patients suffering infarctions exceeding the MCA territory have a comparable chance of favorable recovery as patients with isolated MCA infarction.
Source: Acta Neurochirurgica - December 18, 2017 Category: Neurosurgery Source Type: research

Maximum lesions area and orthogonal values accessed from DWI images would be alternative imaging markers for predicting the outcome of acute ischemia in the middle cerebral artery territory.
Conclusion Since they correlated well with the infarction volume, MaxA and OD assessed on DWI were time-saving and achieved comparable diagnostic efficiencies; thus, they may represent alternative imaging markers for predicting unfavorable outcomes of acute ischemic stroke in MCA territory. PMID: 30130971 [PubMed - as supplied by publisher]
Source: Acta Radiologica - August 21, 2018 Category: Radiology Authors: Yuan T, Ren G, Quan G, Liu Y Tags: Acta Radiol Source Type: research

Efficacy and safety of direct aspiration versus stent-retriever for recanalization in acute cerebral infarction: A PRISMA-compliant systematic review and meta-analysis
Conclusions: The results support that the direct aspiration technique for those acute ischemic stroke patients may have better functional outcomes, less procedure related-adverse events and a tendency of faster revascularization time as compared to the stent-retriever thrombectomy, with a similar successful recanalization rate. However, major limitations of current evidence (mainly from retrospective and observational studies and a small number of patients population) indicate a need for adequately powered, multicenter randomized controlled trials (RCT) to answer this question.
Source: Medicine - October 1, 2018 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Mechanical thrombectomy in acute middle cerebral artery M2 segment occlusion with regard to vessel involvement
ConclusionEVT in patients with acute M2-occlusion is safe and leads to a significant clinical improvement at discharge. No significant differences in clinical outcome or complications were found with regard to the localization of the M2-occlusion.
Source: Neurological Sciences - April 29, 2020 Category: Neurology Source Type: research

Mr. M
Dr. Migliore I step off the subway, up the elevator, and up several flights of stairs. There’s a homeless man there who always uses the last stair of the lower staircase as a tray for his food. And by tray, I mean he sets his half-eaten rice burrito directly onto the step and picks around at it while I imagine the guacamole is mixing with Hep B and C. diff and MRSA. He looks up at me, I promise myself for the 100th time I’m going to start carrying cash or Kind bars or something; I give him my best sheepish face, and emerge at street level. I walk toward my hospital and pass a gentleman who sits on a ledge next to the ...
Source: The Hospitalist - December 1, 2022 Category: Hospital Management Authors: Lisa Casinger Tags: Essay Source Type: research

Prognostic value of pretreatment diffusion-weighted imaging score for acute basilar artery occlusion with successful endovascular recanalization
ConclusionsThe PMT score seems to predict clinical outcome of ABAO patients with successful recanalization.
Source: Neuroradiology - February 8, 2023 Category: Radiology Source Type: research

Exploration of optimal dosing regimens of vancomycin in patients infected with methicillin‐resistant Staphylococcus aureus by modeling and simulation
Summary What is known and objectiveVancomycin is the drug of choice for methicillin‐resistant Staphylococcus aureus (MRSA) infection and shows time‐dependent bacterial killing. The current study evaluated the pharmacokinetics (PK) and pharmacodynamics (PD) of vancomycin and explored its optimal dosing regimens by modeling and simulation. MethodsPharmacokinetics study was performed for 20 patients who were treated with vancomycin intravenously, 1000 mg, every 12 h, and blood for PK was randomly drawn within prespecified time windows. PD study was in vitro time‐kill experiment for vancomycin against 20 MRSA strains i...
Source: Journal of Clinical Pharmacy and Therapeutics - January 16, 2014 Category: Drugs & Pharmacology Authors: H.‐S. Lim, Y. P. Chong, Y.‐H. Noh, J.‐A. Jung, Y. S. Kim Tags: Pharmacokinetics Source Type: research

Outcome of MRSA carriers in neurological early rehabilitation
Background: Colonization with MRSA is believed to have deteriorating effects on neurological rehabilitation patients because MRSA carriers need to be isolated. Methods: Medical records of neurological early rehabilitation patients (most of them after stroke) admitted to a large rehabilitation facility in Northern Germany in 2010 have been carefully reviewed with respect to MRSA status, outcome variables (functional independence), morbidity, and length of stay (LOS). Results: 74/569 (13.0%) patients were MRSA positive on admission. MRSA carriers had a significantly longer LOS in early neurological rehabilitation (63.7 (37.1...
Source: BMC Neurology - February 21, 2014 Category: Neurology Authors: Jens Rollnik Source Type: research

Ruptured brain arteriovenous malformations associated with aneurysms: safety and efficacy of selective embolization in the acute phase of hemorrhage
Conclusion Selective embolization of arterial aneurysms associated with ruptured AVMs is a safe procedure and could lower the immediate risk of rebleeding.
Source: Neuroradiology - September 1, 2014 Category: Radiology Source Type: research

CDC National Health Report: Leading Causes of Morbidity and Mortality and Associated Behavioral Risk and Protective Factors-United States, 2005-2013.
This report reviews population health in the United States and provides an assessment of recent progress in meeting high-priority health objectives. The health status indicators described in this report were selected because of their direct relation to the leading causes of death and other substantial sources of morbidity and mortality and should be the focus of prevention efforts. REPORTING PERIOD COVERED: Data are reported starting in 2005 (or the earliest available year since 2005) through the current data year. Because data sources and specific indicators vary regarding when data are available, the most recent yea...
Source: MMWR Surveill Summ - October 31, 2014 Category: Epidemiology Authors: Johnson NB, Hayes LD, Brown K, Hoo EC, Ethier KA Tags: MMWR Surveill Summ Source Type: research

Nuclear factor-¿B activation in perihematomal brain tissue correlates with outcome in patients with intracerebral hemorrhage
Background: Nuclear factor-κB (NF-κB) plays an important role in the inflammatory response after intracerebral hemorrhage (ICH). We therefore proposed that NF-κB activation in perihematomal brain tissue might correlate with clinical outcome in patients with ICH. To confirm this, we studied clinical data of 45 patients with ICH and NF-κB activation in perihematomal brain tissue and analyzed predictors of clinical outcome as well as the predictive value of NF-κB activation. Methods: Forty-five patients with spontaneous basal ganglia hemorrhage were prospectively investigated. The clinical data were collected, which incl...
Source: Journal of Neuroinflammation - March 15, 2015 Category: Neurology Authors: Ze-Li ZhangYu-Guang LiuQi-Bing HuangHong-Wei WangYan SongZhen-Kuan XuFeng Li Source Type: research

Nuclear factor-κB activation in perihematomal brain tissue correlates with outcome in patients with intracerebral hemorrhage
Background: Nuclear factor-κB (NF-κB) plays an important role in the inflammatory response after intracerebral hemorrhage (ICH). We therefore proposed that NF-κB activation in perihematomal brain tissue might correlate with clinical outcome in patients with ICH. To confirm this, we studied clinical data of 45 patients with ICH and NF-κB activation in perihematomal brain tissue and analyzed predictors of clinical outcome as well as the predictive value of NF-κB activation. Methods: Forty-five patients with spontaneous basal ganglia hemorrhage were prospectively investigated. The clinical data were collected, which incl...
Source: Journal of Neuroinflammation - March 15, 2015 Category: Neurology Authors: Ze-Li ZhangYu-Guang LiuQi-Bing HuangHong-Wei WangYan SongZhen-Kuan XuFeng Li Source Type: research