Sunscreen bans: Coral reefs and skin cancer
This article reviews the reasons and future directions. Hawaii recently enacted legislation that will ban the two major ingredients of the majority of commonly used sunscreens in order to protect marine ecosystems, particularly coral reefs. But sunscreens also save lives by decreasing the risk of UV ‐induced skin cancers. This article reviews the issues and potential implications for healthcare providers. SummaryWhat is known and objectiveHawaii will ban two major ingredients of sunscreens. This article reviews the reasons and future directions. Hawaii recently enacted legislation that will ban the use of two major ingre...
Source: Journal of Clinical Pharmacy and Therapeutics - November 28, 2018 Category: Drugs & Pharmacology Authors: Robert B. Raffa, Joseph V. Pergolizzi, Robert Taylor, Jan M. Kitzen, for the NEMA Research Group Tags: COMMENTARY Source Type: research

Lemierre's syndrome: One rare disease —Two case studies
We present two cases of Lemierre's syndrome with internal jugular vein thrombophlebitis and positive blood cultures forF.  necrophorum. The first case was successfully treated with 6  weeks of a beta‐lactam antibiotic and 4 weeks of metronidazole, while the second case was successfully treated with 4 weeks of a beta‐lactam antibiotic and 2 weeks of metronidazole.What is new and conclusionTwo cases of Lemierre's syndrome were treated successfully with only 2 ‐4 weeks of metronidazole therapy. Shorter duration of metronidazole therapy should be explored in future studies. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - November 28, 2018 Category: Drugs & Pharmacology Authors: Christine Le, Dean Gennaro, Derek Marshall, Orly Alaev, Alicia Bryan, Aleksandra Gelfman, Zhe Wang Tags: CASE REPORT Source Type: research

Comment on “Retrospective study of hypersensitivity reactions to chemotherapeutic agents in a thoracic oncology service”
Journal of Clinical Pharmacy and Therapeutics, EarlyView. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - November 18, 2018 Category: Drugs & Pharmacology Authors: Amir Rezazadeh, Maryam Taghizadeh ‐Ghehi Tags: LETTER TO THE EDITOR Source Type: research

Reducing overestimation of the treatment effect by interim analysis when designing clinical trials
A quantitative evaluation of the magnitude of the overestimation is made according to the characteristics of the trial design, such as the total number of events, number of events in the interim analysis, proportion of the number of events to total events, and the type of α‐spending function. When the total number of events was more than or equal to 300 and the proportion of the interim events was larger than 50%, the overestimation was acceptable. SummaryWhat is known and objectiveSeveral researchers in the statistical and medical communities have noted the overestimation of the treatment effect when a trial is stopped...
Source: Journal of Clinical Pharmacy and Therapeutics - November 10, 2018 Category: Drugs & Pharmacology Authors: Masashi Shimura Tags: ORIGINAL ARTICLE Source Type: research

Differences between activities of coagulation factors after one month of therapy with different direct oral anticoagulant in pulmonary embolism patients
ConclusionApixaban had a significantly higher thrombin activity, above the laboratory determined normal range, compared to patients on rivaroxaban and dabigatran. This higher thrombin activity in patients on apixaban may contribute to a better haemostatic response during the therapy or increased prothrombotic state after therapy interruption. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - November 8, 2018 Category: Drugs & Pharmacology Authors: Jelena Dzudovic, Boris Dzudovic, Vesna Subota, Marko Antunovic, Milena Stavric, Bojana Subotic, Slobodan Obradovic Tags: ORIGINAL ARTICLE Source Type: research

Comparation of vancomycin penetration into cerebrospinal fluid in postoperative intracranial infection and community ‐acquired meningitis patients
Journal of Clinical Pharmacy and Therapeutics, EarlyView. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - October 27, 2018 Category: Drugs & Pharmacology Authors: Yan Cai, Le Zhou, Huqing Wang, Li Zhang, Jinqiu Wang, Kanghuai Zhang Source Type: research

Issue information
Journal of Clinical Pharmacy and Therapeutics,Volume 43, Issue 6, Page i-iv, December 2018. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - October 27, 2018 Category: Drugs & Pharmacology Source Type: research

Clinical outcomes of fidaxomicin vs oral vancomycin in recurrent Clostridium difficile infection
Journal of Clinical Pharmacy and Therapeutics, EarlyView. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - October 23, 2018 Category: Drugs & Pharmacology Authors: Jennifer D. Tieu, Riley J. Williams, Grant H. Skrepnek, Chris A. Gentry Source Type: research

Use of gastric ‐acid suppressants may be a risk factor for enteric peritonitis in patients undergoing peritoneal dialysis: A meta‐analysis
Journal of Clinical Pharmacy and Therapeutics, EarlyView. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - October 17, 2018 Category: Drugs & Pharmacology Authors: Hao ‐Jie Zhong, Da Lin, Zhi‐Yong Lu, Wan‐Ying Yang, Yu Chen Source Type: research

Ulnar neuropathy after glatiramer acetate subcutaneous injection: Ultrasound findings
Journal of Clinical Pharmacy and Therapeutics, EarlyView. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - October 13, 2018 Category: Drugs & Pharmacology Authors: Daniele Coraci, Silvia Giovannini, Claudia Loreti, Luca Padua Source Type: research

Genetic and pharmacogenetic study of glutamate transporter (SLC1A1) in Iranian patients with obsessive ‐compulsive disorder
Journal of Clinical Pharmacy and Therapeutics, EarlyView. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - October 13, 2018 Category: Drugs & Pharmacology Authors: Setareh Abdolhosseinzadeh, Marzie Sina, Abolhassan Ahmadiani, Sareh Asadi, Jamal Shams Source Type: research

Anticholinergic drug use and its association with self ‐reported symptoms among older persons with and without diabetes
Journal of Clinical Pharmacy and Therapeutics, EarlyView. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - October 13, 2018 Category: Drugs & Pharmacology Authors: Niina ‐Mari Inkeri, Merja Karjalainen, Maija Haanpää, Hannu Kautiainen, Juha Saltevo, Pekka Mäntyselkä, Miia Tiihonen Source Type: research

Metamizole (dipyrone) ‐induced agranulocytosis: Does the risk vary according to ethnicity?
Journal of Clinical Pharmacy and Therapeutics, EarlyView. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - October 12, 2018 Category: Drugs & Pharmacology Authors: Rashmi R. Shah Source Type: research

Drug ‐drug interactions among drugs prescribed for nontuberculous mycobacterial infection and epilepsy: A case report
Journal of Clinical Pharmacy and Therapeutics, EarlyView. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - October 12, 2018 Category: Drugs & Pharmacology Authors: Naoki Yoshikawa, Tomoya Tazaki, Mari Hatanaka, Yasuharu Oda, Nobuhiro Matsumoto, Junichiro Sonoda, Ryuji Ikeda Source Type: research

Evaluation of the protective effects of β‐blockers in the management of acute exacerbations of chronic obstructive pulmonary disease
Journal of Clinical Pharmacy and Therapeutics, EarlyView. (Source: Journal of Clinical Pharmacy and Therapeutics)
Source: Journal of Clinical Pharmacy and Therapeutics - October 12, 2018 Category: Drugs & Pharmacology Authors: Cameron D. Thomas, Lori H. Dupree, Marci DeLosSantos, Jason A. Ferreira Source Type: research