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Total 234 results found since Jan 2013.

Total Small Vessel Disease Burden Predicts Functional Outcome in Patients With Acute Ischemic Stroke
Conclusion: Total SVD burden negatively associated with functional outcome at 3 months in patients with acute ischemic stroke and is superior to individual SVD feature in prediction of functional outcome. MRI-based assessment of total SVD burden is highly valuable in clinical management of stroke victims, and could help guide the allocation of resources to improve outcome.
Source: Frontiers in Neurology - August 5, 2019 Category: Neurology Source Type: research

Temporal sustainability of guideline based door-to-needle times for intravenous thrombolysis for acute ischemic stroke
ConclusionIt is possible to sustainably reduce DTN time for IVT in AIS to well below the current 60 min benchmark with hospital system training and teamwork.
Source: Journal of Clinical Neuroscience - February 22, 2020 Category: Neuroscience Source Type: research

Inter-hospital transfer for mechanical thrombectomy within the supraregional stroke network NEVAS
ConclusionWithin a telemedicine network stroke care can successfully be organized as only a minority of patients has to be transferred. Our data provide clinical evidence that all MT-eligible patients should be shipped with the fastest transportation modality as possible.
Source: Journal of Neurology - September 4, 2020 Category: Neurology Source Type: research

Hyper-acute EEG alterations predict functional and morphological outcomes in thrombolysis-treated ischemic stroke: a wireless EEG study
AbstractOwing to the large inter-subject variability, early post-stroke prognosis is challenging, and objective biomarkers that can provide further prognostic information are still needed. The relation between quantitative EEG parameters in pre-thrombolysis hyper-acute phase and outcomes has still to be investigated. Hence, possible correlations between early EEG biomarkers, measured on bedside wireless EEG, and short-term/long-term functional and morphological outcomes were investigated in thrombolysis-treated strokes. EEG with a wireless device was performed in 20 patients with hyper-acute (<  4.5 h from onset) ant...
Source: Medical and Biological Engineering and Computing - December 4, 2020 Category: Biomedical Engineering Source Type: research

The efficacy and safety of fluoxetine versus placebo for stroke recovery: a meta-analysis of randomized controlled trials
ConclusionFluoxetine improved FMMS and reduced anxiety and depression. More well-designed and large sample-size RCTs are required to further analyze the efficacy of fluoxetine in post-stroke recovery.
Source: International Journal of Clinical Pharmacy - April 20, 2023 Category: Drugs & Pharmacology Source Type: research

Mild stroke: safety and outcome in patients receiving thrombolysis.
CONCLUSIONS: This study highlights the efficacy of rt-PA in patients with acute cerebral ischemia presenting with mild symptoms and confirms the low-risk profile of this treatment. PMID: 24588505 [PubMed - in process]
Source: Acta Neurologica Scandinavica. Supplementum - March 9, 2014 Category: Neurology Authors: Logallo N, Kvistad CE, Naess H, Waje-Andreassen U, Thomassen L Tags: Acta Neurol Scand Suppl Source Type: research

Thrombectomy assisted by carotid stenting in acute ischemic stroke management: benefits and harms
This study assesses the benefits and harms of thrombectomy assisted by carotid stenting and identifies factors associated with clinical outcome and procedural complications. Retrospective single-center analysis of 47 consecutive stroke patients with carotid occlusion or high-grade stenosis and concomitant intracranial embolus treated between September 2011 and December 2014. Benefits included early improvement of stroke severity (NIHSS ≥ 10) or complete remission within 72 h and favorable long-term outcome (mRS ≤ 2). Harms included complications during and following EVT. Mean age was 64.3 years (standard deviatio...
Source: Journal of Neurology - September 7, 2015 Category: Neurology Source Type: research

Severity and outcomes according to stroke etiology in patients under 50 years of age with ischemic stroke
Abstract To analyze the association of stroke etiological subtypes with severity and outcomes at 3 and 12 months in patients ≤50 years. Observational study of patients admitted to a stroke unit (2007–2013). Variables: demographic data, vascular risk factors, comorbidities, severity on admission (NIHSS), and good functional outcome (mRS ≤ 1) at 3 and 12 months. We used multivariate analyses to evaluate the influence of stroke etiology on severity and outcomes. We included 214 patients, 58.3 % men, mean age 41.4 years. General linear models showed all etiologies were more severe than lacunar strokes (P...
Source: Journal of Thrombosis and Thrombolysis - February 5, 2016 Category: Hematology Source Type: research

Plasma miR-124-3p and miR-16 concentrations as prognostic markers in acute stroke.
CONCLUSIONS: Plasma miR-124-3p and miR-16 are molecular markers which could be useful for the early prediction of mortality and mRS. PMID: 26968104 [PubMed - as supplied by publisher]
Source: Clinical Biochemistry - March 9, 2016 Category: Biochemistry Authors: Rainer TH, Leung LY, Chan CP, Leung YK, Abrigo JM, Wang D, Graham CA Tags: Clin Biochem Source Type: research

Endovascular thrombectomy and medical therapy versus medical therapy alone in acute stroke: A randomized care trial
Conclusion A care trial was implemented to offer verifiable care to acute stroke patients. This approach offers a promising means to manage clinical dilemmas and guide uncertain practices.
Source: Journal of Neuroradiology - February 24, 2017 Category: Radiology Source Type: research

Clinical outcomes of acute ischemic stroke patients treated by direct catheter-based trombectomy depending on their baseline characteristics
Conclusions Mechanical thrombectomy achieved better clinical results in younger patients, in smokers and in patients with stroke not caused by atrial fibrillation.
Source: Cor et Vasa - January 30, 2018 Category: Cardiology Source Type: research

Results and functional outcomes of acute ischemic stroke patients who underwent mechanical thrombectomy admitted to intensive care unit
Conclusions The factors relating to a worse functional outcome were symptomatic hemorrhage transformation, lack of recanalization and complications during EVT. The factors relating to mortality were symptomatic hemorrhage and hydrocephalus. Distal flow was achieve in most cases with a low complication rate. Half of the patients presented functional independence one year after the stroke.
Source: Medicina Intensiva - May 30, 2018 Category: Intensive Care Source Type: research

Safety of urgent endarterectomy in acute non ‐disabling stroke patients with symptomatic carotid artery stenosis: an international multicenter study
ConclusionsOur findings highlight that urgent CEA performed within two days from the index event is related to a non ‐significant increase in the risk of peri‐procedural stroke. The safety of urgent CEA requires further evaluation in larger datasets.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - November 25, 2018 Category: Neurology Authors: Andromachi Roussopoulou, Georgios Tsivgoulis, Christos Krogias, Andreas Lazaris, Konstantinos Moulakakis, George S. Georgiadis, Robert Mikulik, John D. Kakisis, Christina Zompola, Simon Faissner, Maria Chondrogianni, Chrissoula Liantinioti, Th Tags: Original Article Source Type: research

Number of Stentriever Passes and Outcome after Thrombectomy in Stroke
Conclusions:The number of passes needed to achieve target vessel recanalization modifies outcome after thrombectomy and successful recanalization after a single pass is associated with favorable outcome.
Source: Journal of Neuroradiology - April 12, 2019 Category: Radiology Source Type: research