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Total 234 results found since Jan 2013.

Associated factors with functional prognosis of patients with acute ischemic stroke undergoing thrombectomy
CONCLUSION: Age, T2D and failed recanalization increase risk for unfavorable outcome at 90 days in patients with AIS treated with MT. Procedure time duration should be considered as a possible determinant factor in functional outcome.PMID:35042605 | DOI:10.1016/j.medcli.2021.11.010
Source: Medicina Clinica - January 19, 2022 Category: General Medicine Authors: Íñigo Rodríguez-Baz Mar ía Cristo Rodríguez-Pérez Antonio Medina Rodr íguez Ignacio Hern ández Cabezudo Yolanda Sosa Cabrera Source Type: research

Prognostic value of the systemic inflammation response index in patients with acute ischemic stroke
ConclusionSIRI is an independent prognostic indicator for AIS. Elevated SIRI is associated with poor functional outcome of AIS. Our findings suggest the usefulness of SIRI to refine the risk stratification of unfavorable prognosis of AIS.
Source: Brain and Behavior - May 19, 2022 Category: Neurology Authors: Yaping Zhou, Yidi Zhang, Mingming Cui, Yuming Zhang, Xiuli Shang Tags: ORIGINAL ARTICLE Source Type: research

Prediction of blood pressure variability during thrombectomy using supervised machine learning and outcomes of patients with ischemic stroke from large vessel occlusion
AbstractMechanical thrombectomy (MT) is the standard of care for patients with acute ischemic stroke from large vessel occlusion (AIS-LVO). The association of blood pressure variability (BPV) during MT and outcomes are unknown. We leveraged a supervised machine learning algorithm to predict patient characteristics that are associated with BPV indices. We performed a retrospective review of our comprehensive stroke center ’s registry of all adult patients undergoing MT between 01/01/2016 and 12/31/2019. The primary outcome was poor functional independence, defined as 90-day modified Rankin Scale (mRS) ≥ 3. We used p...
Source: Journal of Thrombosis and Thrombolysis - April 12, 2023 Category: Hematology Source Type: research

Acute Stroke and Obstruction of the Extracranial Carotid Artery Combined with Intracranial Tandem Occlusion: Results of Interventional Revascularization
Conclusion Endovascular recanalization of acute cervical carotid artery occlusion was technically feasible in all patients, and resulted in high extra- and intracranial revascularization rates. A trend for favorable clinical outcome was seen in a higher TICI score, younger age, good collateral status, and combined IV rTPA and endovascular therapy.
Source: CardioVascular and Interventional Radiology - December 30, 2014 Category: Radiology Source Type: research

Effective management of patients with acute ischemic stroke based on lean production on thrombolytic flow optimization
In this study, we aimed to determine whether applying lean principles to flow optimization could hasten the initiation of thrombolysis. A multidisciplinary team (Stroke Team) was organized to implement an ongoing, continuous loop of lean production that contained the following steps: decomposition, recognition, intervention, reengineering and assessment. The door-to-needle time (DNT) and the percentage of patients with DNT ≤ 60 min before and after the adoption of lean principles were used to evaluate the efficiency of our flow optimization. Thirteen patients with AIS in the pre-lean period and 43 patients with AIS in...
Source: Australasian Physical and Engineering Sciences in Medicine - April 18, 2016 Category: Biomedical Engineering Source Type: research

Association between Leukoaraiosis and Poor Outcome is not due to Reperfusion Inefficiency after Intravenous Thrombolysis
Abstract Leukoaraiosis (LA) is associated with structural and functional cerebrovascular impairment, which may compromise the capacity of ischemic tissue to maximize reperfusion after intravenous thrombolysis (IVT). We aimed to determine whether severe LA is correlated with reperfusion inefficiency, which contributes to infarct growth and poor functional outcome. We analyzed data from our consecutive acute ischemic stroke (AIS) patients who had acquired baseline and 24-h follow-up diffusion- and perfusion-weighted imaging. Reperfusion was defined as reduction of ≥70 % of hypoperfusion lesion at 24 h from basel...
Source: Translational Stroke Research - June 1, 2016 Category: Neurology Source Type: research

Intravenous thrombolysis for patients with in ‐hospital stroke onset: propensity‐matched analysis from the SITS‐EAST registry
ConclusionsOur findings underline the safety and efficacy of IVT for IHS. They also underscore the potential of reducing in‐hospital delays for timely tPA delivery in patients with IHS.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - September 9, 2017 Category: Neurology Authors: Georgios Tsivgoulis, Aristeidis H. Katsanos, Pavla Kadlecov á, Anna Czlonkowska, Adam Kobayashi, Miroslav Brozman, Viktor Švigelj, Laszlo Csiba, Klara Fekete, Janika Kõrv, Vida Demarin, Aleksandras Vilionskis, Dalius Jatuzis, Yakup Krespi, Theodore Kar Tags: Original Article Source Type: research

Iatrogenic Vessel Dissection in Endovascular Treatment of Acute Ischemic Stroke
ConclusionThe occurrence of ID is a  rare complication of endovascular AIS treatment associated with smoking and mechanical thrombectomy.
Source: Clinical Neuroradiology - November 2, 2017 Category: Neurology Source Type: research

Early microvascular cerebral blood flow response to head-of-bed elevation is related to outcome in acute ischemic stroke
ConclusionsEarly CBF response to mild HOB elevation in the ipsilesional hemisphere is related to functional outcome. Further studies may enable optical monitoring at the bedside to individualize management strategies in the early phase of AIS.
Source: Journal of Neurology - February 9, 2019 Category: Neurology Source Type: research

Efficacy of ADAPT with large-bore reperfusion catheter in anterior circulation acute ischemic stroke: a multicentric Italian experience
ConclusionsADAPT is a valid technique with respect to the rates of TICI 2b/3 recanalization and 90-day mRS scores. In this series, an attempt at recanalization with ADAPT with larger-bore reperfusion catheter may be warranted prior to stentriever thrombectomy.
Source: La Radiologia Medica - August 30, 2019 Category: Radiology Source Type: research

Safety and effectiveness of CATCH+ as a first-line device for revascularization in the treatment of acute ischemic stroke
Conclusions: The CATCH+ device is a safe and effective mechanical thrombectomy device for the first-line treatment of acute ischemic stroke.
Source: Journal of Neuroradiology - September 18, 2019 Category: Radiology Source Type: research

Collateral Scores in Acute Ischemic Stroke
ConclusionAlthough collaterals are known to correlate with clinical outcome, none of the analyzed collateral scores sufficiently predicted outcome as a  standalone parameter.
Source: Clinical Neuroradiology - November 27, 2019 Category: Neurology Source Type: research

Mechanical Thrombectomy in Acute Ischemic Stroke Using a  Manually Expandable Stent Retriever (Tigertriever)
ConclusionThe Tigertriever offers a  safe and effective treatment option in ischemic stroke due to LVOs with reperfusion rates and a safety profile similar to alternative devices. The Tigertriever is a promising bail-out tool in complex cases. Its role as a first line device has to be evaluated in further prospective studies.
Source: Clinical Neuroradiology - June 10, 2020 Category: Neurology Source Type: research

Use of intracranial stent as rescue therapy after mechanical thrombectomy failure —9-year experience in a comprehensive stroke centre
ConclusionPlacement of an intracranial stent as rescue therapy after MT failure was associated with better clinical outcome without significant increase in haemorrhagic complications. We believe that this procedure should be appraised in these patients.
Source: Neuroradiology - June 29, 2020 Category: Radiology Source Type: research