Weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region
ConclusionThe real efficacy of this treatment in the therapeutic arsenal remains to be defined. A clinical trial is ongoing to test the use of 8 weekly fractions of 8  Gy hypofractionated RT regimens in non-resectable cSCC cases. (Source: La Radiologia Medica)
Source: La Radiologia Medica - October 15, 2020 Category: Radiology Source Type: research

Clinical and laboratory data, radiological structured report findings and quantitative evaluation of lung involvement on baseline chest CT in COVID-19 patients to predict prognosis
ConclusionIn conclusion, both CT visual score and computerized software-based quantification of the consolidation, emphysema and residual healthy lung parenchyma on chest CT images were independent predictors of outcome in patients with COVID-19 pneumonia. (Source: La Radiologia Medica)
Source: La Radiologia Medica - October 12, 2020 Category: Radiology Source Type: research

Prognostic value of cardiac CT
AbstractIn the past decades, coronary computed tomography angiography (CCTA) has become a powerful tool in the management of coronary artery disease. The diagnostic and prognostic value of CCTA has been extensively demonstrated in both large observational studies and clinical trials among stable chest pain patients. The quantification of coronary artery calcium score (CACS) is a well-established predictor of cardiovascular morbidity and mortality in asymptomatic subjects. Besides CACS, the main strength of CCTA is the accurate assessment of the individual total atherosclerotic plaque burden, which holds important prognosti...
Source: La Radiologia Medica - October 12, 2020 Category: Radiology Source Type: research

Renal artery embolization of non-functioning graft: an effective treatment for graft intolerance syndrome
ConclusionsAccording to the scientific literature, we believe that, in selected patients, percutaneous renal artery embolization is a valid treatment option for GIS thanks to its efficacy, repeatability, minimal invasiveness and the absence of severe complications. (Source: La Radiologia Medica)
Source: La Radiologia Medica - October 12, 2020 Category: Radiology Source Type: research

Third-generation iterative reconstruction on a dual-source, high-pitch, low-dose chest CT protocol with tin filter for spectral shaping at 100  kV: a study on a small series of COVID-19 patients
AbstractObjectivesTo investigate the role of third-generation iterative reconstruction (ADMIRE) in dual-source, high-pitch chest CT protocol with spectral shaping at 100 kVp in Coronavirus disease 2019 (COVID-19).MethodsConfirmed COVID-19 inpatients undergoing to unenhanced chest CT were scanned with a dual-energy acquisition (DECT, 90/150Sn kV) and a dual-source, high-pitch acquisition with tin-filtered 100  kVp (LDCT). On the DECT with ADMIRE 3 (DECT3) were evaluated the pulmonary findings and their extension (25-point score). Two radiologists in consensus evaluated with 5-point scales the overall image quality, the...
Source: La Radiologia Medica - October 12, 2020 Category: Radiology Source Type: research

Quantitative Chest CT analysis in discriminating COVID-19 from non-COVID-19 patients
AbstractIntroductionCOVID-19 pneumonia is characterized by ground-glass opacities (GGOs) and consolidations on Chest CT, although these CT features cannot be considered specific, at least on a qualitative analysis. The aim is to evaluate if Quantitative Chest CT could provide reliable information in discriminating COVID-19 from non-COVID-19 patients.Materials and methodsFrom March 31, 2020 until April 18, 2020, patients with Chest CT suggestive for interstitial pneumonia were retrospectively enrolled and divided into two groups based on positive/negative COVID-19 RT-PCR results. Patients with pulmonary resection and/or CT ...
Source: La Radiologia Medica - October 12, 2020 Category: Radiology Source Type: research

Myocarditis: imaging up to date
AbstractMyocarditis is an inflammatory disease of the heart muscle, diagnosed by histological, immunological, and immunohistochemical criteria. Endomyocardial biopsy represents the diagnostic gold standard for its  diagnosis but is infrequently used. Due to its noninvasive ability to detect the presence of myocardial edema, hyperemia and necrosis/fibrosis, Cardiac MR imaging is routinely used in the clinical practice for the diagnosis of acute myocarditis. Recently pixel-wise mapping of T1 and T2 relaxation time have been introduced into the clinical Cardiac MR protocol increasing its accuracy. Our paper will review t...
Source: La Radiologia Medica - October 5, 2020 Category: Radiology Source Type: research

Dosimetric analysis of the effects of a temporary tissue expander on the radiotherapy technique
ConclusionThe presence of the metal port within the TTE in radiation fields resulted to insignificant increased dose differences according to the treatment technique. Future studies should assess whether this dose difference could affect clinical outcomes. (Source: La Radiologia Medica)
Source: La Radiologia Medica - October 5, 2020 Category: Radiology Source Type: research

A snapshot on radiotherapy for head and neck cancer patients during the COVID-19 pandemic: a survey of the Italian Association of Radiotherapy and Clinical Oncology (AIRO) head and neck working group
ConclusionsCompared to pre-COVID era, the clinical workflow was highly re-organized, whereas there were no consistent changes in RT indications and schedules. (Source: La Radiologia Medica)
Source: La Radiologia Medica - October 5, 2020 Category: Radiology Source Type: research

The lingering manifestations of COVID-19 during and after convalescence: update on long-term pulmonary consequences of coronavirus disease 2019 (COVID-19)
AbstractThe long-term sequelae of coronavirus disease 2019 (COVID-19) are still unknown. Lessons from past viral epidemics reveal that, after recovery, patients with viral pulmonary infections can suffer from irreversible pulmonary dysfunction and demonstrate residual imaging or functional abnormalities. Residual ground glass opacities, consolidations, reticular and linear opacities, residual crazy paving pattern, melted sugar sign, and parenchymal fibrotic bands are several features found in the late or remission stages of COVID-19. These radiologic findings have been observed weeks after symptom onset, even after hospita...
Source: La Radiologia Medica - September 30, 2020 Category: Radiology Source Type: research

Cardiac magnetic resonance in arrhythmogenic cardiomyopathies
AbstractOver the past few years, the approach to the ‘arrhythmic patient’ has profoundly changed. An early clinical presentation of arrhythmia is often accompanied by non-specific symptoms and followed by inconclusive electrocardiographic findings. In this scenario, cardiac magnetic resonance (CMR) has been established as a clinical tool of fundam ental importance for a correct prognostic stratification of the arrhythmic patient. This technique provides a high-spatial-resolution tomographic evaluation of the heart, which allows studying accurately the ventricular volumes, identifying even segmental kinetic anom...
Source: La Radiologia Medica - September 24, 2020 Category: Radiology Source Type: research

Cardiac-CT and cardiac-MR cost-effectiveness: a literature review
AbstractCardiovascular diseases are still among the first causes of death worldwide with a huge impact on healthcare systems. Within these conditions, the correct diagnosis of coronary artery disease with the most appropriate imaging-based evaluations is of utmost importance. The sustainability of the healthcare systems, considering the high economic burden of modern cardiac imaging equipments, makes cost-effective analysis an important tool, currently used for weighing different costs and health outcomes, when policy makers have to allocate funds and to prioritize interventions, getting the most out of their financial res...
Source: La Radiologia Medica - September 23, 2020 Category: Radiology Source Type: research

Cardiovascular magnetic resonance (CMR) in restrictive cardiomyopathies
AbstractThe restrictive cardiomyopathies constitute a heterogeneous group of myocardial diseases with a different pathogenesis and overlapping clinical presentations. Diagnosing them frequently poses a challenge. Echocardiography, electrocardiograms and laboratory tests may show non-specific changes. In this context, cardiac magnetic resonance (CMR) may play a crucial role in defining the diagnosis and guiding treatments, by offering a robust myocardial characterization based on the inherent magnetic properties of abnormal tissues, thus limiting the use of endomyocardial biopsy. In this review article, we explore the role ...
Source: La Radiologia Medica - September 23, 2020 Category: Radiology Source Type: research

Value of Canadian C-spine rule versus the NEXUS criteria in ruling out clinically important cervical spine injuries: derivation of modified Canadian C-spine rule
ConclusionsThe modified Canadian C-spine rule has fewer variables than the original Canadian C-spine rule and is entirely based on physical examination, which seems easier to use in emergency departments. (Source: La Radiologia Medica)
Source: La Radiologia Medica - September 22, 2020 Category: Radiology Source Type: research

The current landscape of imaging recommendations in cardiovascular clinical guidelines: toward an imaging-guided precision medicine
AbstractThe purpose of this article is to provide an overview on the role of CT scan and MRI according to selected guidelines by the European Society of Cardiology (ESC) and the American College of Cardiology/American Heart Association (ACC/AHA). ESC and ACC/AHA guidelines were systematically reviewed for recommendations to CT and MRI use in specific cardiovascular (CV) clinical categories. All recommendations were collected in a dataset, including the class of recommendation, the level of evidence (LOE), the specific imaging technique, the clinical purpose of the recommendation and the recommending Society. Among the 43 i...
Source: La Radiologia Medica - September 21, 2020 Category: Radiology Source Type: research

CCTA in the diagnosis of coronary artery disease
AbstractThe world of cardiac imaging is proposing to physicians an ever-increasing spectrum of options and tools with the disadvantages of patients presently submitted to multiple, sequential, time-consuming, and costly diagnostic procedures and tests, sometimes with contradicting results. In the last two decades, the CCTA has evolved into a valuable diagnostic test in today ’s patient care, changing the official existing guidelines and clinical practice with a pivotal role to exclude significant CAD, in the referral of patients to the Cath-Lab, in the follow-up after coronary revascularization, and finally in the ca...
Source: La Radiologia Medica - September 21, 2020 Category: Radiology Source Type: research

Noninvasive imaging of congenital cardiovascular defects
AbstractAdvances in the treatment have drastically increased the survival rate of congenital heart disease (CHD) patients. Therefore, the prevalence of these patients is growing. Imaging plays a crucial role in the diagnosis and management of this population as a key component of patient care at all stages, especially in those patients who survived into adulthood. Over the last decades, noninvasive imaging techniques, such as cardiac magnetic resonance (CMR) and cardiac computed tomography (CCT), progressively increased their clinical relevance, reaching stronger levels of accuracy and indications in the clinical surveilla...
Source: La Radiologia Medica - September 20, 2020 Category: Radiology Source Type: research

TAVI imaging: over the echocardiography
AbstractAortic valve stenosis (AS) is a common valvular heart disease. Recently, transcatheter aortic valve implantation (TAVI) has changed the treatment of severe AS in elderly patients with contraindications to traditional surgical replacement. Echocardiography is conventionally used as the first imaging modality to assess the presence and severity of AS and to provide anatomical and functional information. Nowadays, imaging techniques play a crucial role in the planning of TAVI to define suitable candidates. Computed tomography (CT) is essential to display the anatomy of the aortic valve complex (including aortic annulu...
Source: La Radiologia Medica - September 17, 2020 Category: Radiology Source Type: research

Artificial intelligence in cardiac radiology
AbstractArtificial intelligence (AI) is entering the clinical arena, and in the early stage, its implementation will be focused on the automatization tasks, improving diagnostic accuracy and reducing reading time. Many studies investigate the potential role of AI to support cardiac radiologist in their day-to-day tasks, assisting in segmentation, quantification, and reporting tasks. In addition, AI algorithms can be also utilized to optimize image reconstruction and image quality. Since these algorithms will play an important role in the field of cardiac radiology, it is increasingly important for radiologists to be famili...
Source: La Radiologia Medica - September 17, 2020 Category: Radiology Source Type: research

Cardiac magnetic resonance in hypertrophic and dilated cardiomyopathies
AbstractCardiomyopathies are a heterogeneous entity. The progress in the field of genetics has allowed over the years to determine its origin more and more often. The classification of these pathologies has changed over the years; it has been updated with new knowledge. Imaging allows to define the phenotypic characteristics of the different forms of cardiomyopathy. Cardiac magnetic resonance (CMR) allows a morphological evaluation of the associated (and sometimes pathognomonic) cardiac findings of any form of cardiomyopathy. The tissue characterization sequences also make magnetic resonance imaging unique in its ability t...
Source: La Radiologia Medica - September 17, 2020 Category: Radiology Source Type: research

Cardiac MRI: technical basis
AbstractCardiac magnetic resonance (CMR) imaging is an effective method for noninvasively imaging the heart which in the last two decades impressively enhanced spatial and temporal resolution and imaging speed, broadening its spectrum of applications in cardiovascular disease. CMR imaging techniques are designed to noninvasively assess cardiovascular morphology, ventricular function, myocardial perfusion, tissue characterization, flow quantification and coronary artery disease. These intrinsic features yield CMR suitable for diagnosis, follow-up and longitudinal monitoring after treatment of cardiovascular diseases. The ai...
Source: La Radiologia Medica - September 15, 2020 Category: Radiology Source Type: research

CMR in the diagnosis of ischemic heart disease
AbstractCardiovascular magnetic resonance has always been more often used in the last 10  years in evaluation of heart disease. Role in diagnosis of ischemia and in evaluation of myocardial infarction is well established by many scientific papers and included in current guidelines. High accuracy in evaluation of stress-induced ischemia, tissue characterization and functional parameters are the pillars the make the method widely used. In this paper are described role and techniques in diagnosis of ischemia, myocardial infarction and its sequelae. (Source: La Radiologia Medica)
Source: La Radiologia Medica - September 15, 2020 Category: Radiology Source Type: research

The sub-millisievert era in CTCA: the technical basis of the new radiation dose approach
AbstractComputed tomography coronary angiography (CTCA) has become a cornerstone in the diagnostic process of the heart disease. Although the cardiac imaging with interventional procedures is responsible for approximately 40% of the cumulative effective dose in medical imaging, a relevant radiation dose reduction over the last decade was obtained, with the beginning of the sub-mSv era in CTCA. The main technical basis to obtain a radiation dose reduction in CTCA is the use of a low tube voltage, the adoption of a prospective electrocardiogram-triggering spiral protocol and the application of the tube current modulation wit...
Source: La Radiologia Medica - September 14, 2020 Category: Radiology Source Type: research

Intra- and inter-observer variability in intracranial aneurysm segmentation: comparison between CT angiography (semi-automated segmentation software stroke VCAR) and digital subtraction angiography (3D rotational angiography)
ConclusionThe examined 3D-CTA segmentation system is a reproducible procedure for aneurysm morphologic characterization and, in particular, for assessment of aneurysm sac dimensions, but considerable carefulness is required in neck length interpretation. (Source: La Radiologia Medica)
Source: La Radiologia Medica - September 8, 2020 Category: Radiology Source Type: research

Radiation dose reduction considerations and imaging patterns of ground glass opacities in coronavirus: risk of over exposure in computed tomography
This article aims to summarize the available data on the severe acute respiratory syndrome coronavirus 2 (SAR-CoV-2) imaging patterns as well as reducing radiation dose exposure in chest computed tomography (CT) protocols. First, the general aspects of radiation dose in CT and radiation risk are discussed, followed by the effect of changing parameters on image quality. This article attempts to highlight some of the common chest CT signs that radiologists and emergency physicians are likely to encounter. With the increasing trend of using chest CT scans as an imaging tool to diagnose and monitor SAR-CoV-2, we emphasize that...
Source: La Radiologia Medica - September 7, 2020 Category: Radiology Source Type: research

Baseline chest X-ray in coronavirus disease 19 (COVID-19) patients: association with clinical and laboratory data
ConclusionCXR has a low sensitivity. LDH, CRP and interval between the onset of symptoms and the execution of CXR are major predictors for a positive CXR. (Source: La Radiologia Medica)
Source: La Radiologia Medica - September 6, 2020 Category: Radiology Source Type: research

The role of rare breast cancers in the false negative strain elastography results
ConclusionThe rare breast cancers are an important cause of false negativity in elastographic evaluation of invasive breast cancers. The results should be interpreted in combination with grayscale US findings. (Source: La Radiologia Medica)
Source: La Radiologia Medica - September 6, 2020 Category: Radiology Source Type: research

Embolization of peripheral arteriovenous malformations and fistulas with precipitating hydrophobic injectable liquid (PHIL ® )
ConclusionsPHIL® seems to be a safe and effective liquid embolic agent for the treatment of peripheral AVMs and fistulas; although a direct comparison between PHIL and Onyx was not performed, PHIL might present the advantages of reduced artifacts at postprocedural CT scan and no need for shaking time preparation, but it is more expensive due to lower volume of product for each package and slightly less radiopaque at fluoroscopy. (Source: La Radiologia Medica)
Source: La Radiologia Medica - September 4, 2020 Category: Radiology Source Type: research

Clinical significance of radiation dose –volume parameters and functional status on the patient-reported quality of life changes after thoracic radiotherapy for lung cancer: a prospective study
AbstractPurposeTo date, limited data exist about the relationship between radiation dose –volume parameters and patient-reported quality of life (QOL) after thoracic radiotherapy (RT) for lung cancer. We conducted this prospective study to investigate which clinico-dosimetric factors have an impact on functional declines and symptom developments after thoracic RT for lung cancer.Materials and methodsThe study included 44 patients who had underwent thoracic three-dimensional conformal RT at our institution from 2016 to 2017. The health-related QOL was assessed using the EORTC QLQ-C30 and QLQ-LC13 questionnaires before...
Source: La Radiologia Medica - September 4, 2020 Category: Radiology Source Type: research

Chest CT in patients with a moderate or high pretest probability of COVID-19 and negative swab
AbstractObjectivesWe aimed to assess the diagnostic performance of CT in patients with a negative first RT-PCR testing and to identify typical features of COVID-19 pneumonia that can guide diagnosis in this case.MethodsPatients suspected of COVID-19 with a negative first RT-PCR testing were retrospectively revalued after undergoing CT.CT was reviewed by two radiologists and classified as suspected COVID-19 pneumonia, non-COVID-19 pneumonia or negative.The performance of both first RT-PCR result and CT was evaluated by using sensitivity (SE), specificity (SP), positive predictive value (PPV), negative predictive value (NPV)...
Source: La Radiologia Medica - August 28, 2020 Category: Radiology Source Type: research

Does measurement of the jugular foramen diameter on MRI help to differentiate transverse sinus thrombosis from unilateral transverse sinus hypoplasia?
AbstractBackground and PurposeThe transverse sinus (TS) is a frequent location of cerebral venous thrombosis. However, unilateral TS hypoplasia is a frequent variation and radiological imaging pitfall in the diagnosis because it may mimic unilateral TS thrombosis. The purpose of this study is to find a cutoff value for bilateral jugular foramen (JF) diameter ratios on magnetic resonance imaging (MRI) for differentiating TS thrombosis from TS hypoplasia.Materials and MethodsWe retrospectively reviewed magnetic resonance venography results for 174 patients with reduced unilateral TS caliber resulting from either unilateral t...
Source: La Radiologia Medica - August 27, 2020 Category: Radiology Source Type: research

PROACTA: a survey on the actual attitude of the Italian radiation oncologists in the management and prescription of hormonal therapy in prostate cancer patients
ConclusionOur survey established the prescription attitude of ADT and new hormonal agents (abiraterone, enzalutamide, apalutamide) by Italian Radiation Oncologists and highlighted the importance of expertise in global PC management. (Source: La Radiologia Medica)
Source: La Radiologia Medica - August 26, 2020 Category: Radiology Source Type: research

Identification of bone marrow edema of the knee: diagnostic accuracy of dual-energy CT in comparison with MRI
AbstractBackgroundTo assess the diagnostic accuracy of dual-energy computed tomography (DECT) in diagnosing bone marrow edema (BME) of the knee in traumatic and non-traumatic patients.MethodsThis prospective IRB approved study included 33 consecutive patients (20 males, 13 females; mean age of 52.2  years) evaluated with DECT (80 and 150 kV) and MRI within 6 days. Two experienced radiologists qualitatively and quantitatively evaluated DECT images. The accuracy values were calculated by using receiver operator curves (ROC) and area under the curve (AUC), using MRI as the reference standard. Inter-observer and...
Source: La Radiologia Medica - August 24, 2020 Category: Radiology Source Type: research

A field strength independent MR radiomics model to predict pathological complete response in locally advanced rectal cancer
ConclusionsThe model elaborated showed good performance, even when data from patients scanned on 1.5  T and 3 T were merged. This shows that magnetic field intensity variability can be overcome by means of selecting appropriate image features. (Source: La Radiologia Medica)
Source: La Radiologia Medica - August 23, 2020 Category: Radiology Source Type: research

Practical instructions for using drugs in CT and MR cardiac imaging
AbstractThe progressive increase in numbers of noninvasive cardiac imaging examinations broadens the spectrum of knowledge radiologists are expected to acquire in the management of drugs during CT coronary angiography (CTCA) and cardiac MR (CMR) to improve image quality for optimal visualization and assessment of the coronary arteries and adequate MR functional analysis. Aim of this review is to provide an overview on different class of drugs (nitrate, beta-blockers, ivabradine, anxiolytic, adenosine, dobutamine, atropine, dipyridamole and regadenoson) that can be used in CTCA and CMR, illustrating their main indications, ...
Source: La Radiologia Medica - August 23, 2020 Category: Radiology Source Type: research

Accuracy of unenhanced CT in the diagnosis of cerebral venous sinus thrombosis
AbstractObjectivesTo evaluate the diagnostic performance of unenhanced brain CT (NECT) in identifying patients with cerebral venous sinus thrombosis (CVT).MethodsForty-eight consecutive patients with CVT and 48 healthy controls were included in our retrospective study. All patients underwent NECT and CT/MR angiography within 24  h. Two radiologists independently evaluated NECT images for the presence of sinus hyperdensity; discrepancies were solved by consensus. Sinus attenuation was measured in seven sites. The obtained data were compared with the presence of CVT at CT/MR angiography and with patients' hematocrit.Res...
Source: La Radiologia Medica - August 23, 2020 Category: Radiology Source Type: research

Quantitative bone marrow magnetic resonance imaging through apparent diffusion coefficient and fat fraction in multiple myeloma patients
AbstractObjectiveQuantitative bone marrow (BM) MR sequences, as DWI and CSI, were used to evaluate BM water –fat composition. The aim of the study was to assess the potential usefulness of fat fraction (FF) and ADC, calculated by CSI or DWI, in diagnosing and classifying myeloma (MM) patients according to their different BM infiltration patterns.MethodsThe study group included 43 MM patients (19F; 24M; mean age 64  years), 15 asymptomatic, 15 symptomatic with diffuse BM infiltration and 13 symptomatic with focal lesions (FLs). The control group was made up of 15 healthy subjects (7F; 8M; mean age 64 years)....
Source: La Radiologia Medica - August 17, 2020 Category: Radiology Source Type: research

Correction to: MR imaging of cerebral involvement of Rosai –Dorfman disease: a single-centre experience with review of the literature
In the original publication, the first and last name of the Author “Giorgia Saltelli” was inadvertently swapped. The correct Author group has been provided below. (Source: La Radiologia Medica)
Source: La Radiologia Medica - August 17, 2020 Category: Radiology Source Type: research

A technique for quantifying the sensitivity of dosimetric tool gamma with 2D detector array in pretreatment IMRT plans by segment deletion method
ConclusionsThe 2D detector array with dosimetric tool gamma is less sensitive in detecting errors when unprecedented errors of segment deletion occur within the treatment plans. (Source: La Radiologia Medica)
Source: La Radiologia Medica - August 16, 2020 Category: Radiology Source Type: research

Chest CT for early detection and management of coronavirus disease (COVID-19): a report of 314 patients admitted to Emergency Department with suspected pneumonia
AbstractPurposeThe purpose of our study was to assess the potential role of chest CT in the early detection of COVID-19 pneumonia and to explore its role in patient management in an adult Italian population admitted to the Emergency Department.MethodsThree hundred and fourteen patients presented with clinically suspected COVID-19, from March 3 to 23, 2020, were evaluated with PaO2/FIO2 ratio from arterial blood gas, RT-PCR assay from nasopharyngeal swab sample and chest CT. Patients were classified as COVID-19 negative and COVID-19 positive according to RT-PCR results, considered as a reference. Images were independently e...
Source: La Radiologia Medica - July 28, 2020 Category: Radiology Source Type: research

Is concomitant treatment with steroids and radiotherapy more favorable than sequential treatment in moderate-to-severe graves orbitopathy?
AbstractPurposeGlucocorticoids (GCs) and external radiotherapy (RT) are used for treating moderate-to-severe Graves ’ orbitopathy (GO). We aimed to assess whether GCs and RT were more effective when administered concomitantly or sequentially.MethodsWe retrospectively analyzedclinical outcomes [assessed by Clinical Activity Score (CAS) and NOSPECS classification] in 73 patients treated with both i.v. GCs and RT. The patients were divided in two groups: In group A (53 patients), RT was delivered concomitantly with GCs, and in group B (20 patients) RT was administered subsequently to the end of methylprednisolone.Result...
Source: La Radiologia Medica - July 22, 2020 Category: Radiology Source Type: research

ODLURO syndrome: personal experience and review of the literature
AbstractIntroductionThe O ’Donnell–Luria–Rodan (ODLURO) syndrome, caused by heterozygous mutation in the lysineN-methyltransferase2E (KMT2E) gene in chromosome 7q22, has been recently described. Mutation of KMT2E produces a protein-truncating variant gene that may be responsible for both developmental delay and intellectual disability disorders commonly defined by an Intelligence Quotient  
Source: La Radiologia Medica - July 19, 2020 Category: Radiology Source Type: research

The value of coronal view as a stand-alone assessment in women undergoing automated breast ultrasound
AbstractBackgroundAim of the study was to evaluate the value of automated breast ultrasound (AUS) in women with dense breast, in terms of reading times, diagnostic performance and interobserver agreement. The assessment of coronal images alone versus the complete multiplanar (MPR) views was evaluated.MethodsBetween August and October 2017, consecutive patients with dense breast that were referred to our Institute, for post-mammography ultrasound assessment, pre-operative assessment or follow-up of known benign lesions, were invited to undergo an additional study with AUS. Three radiologists, (5, 15 and 25  years of ex...
Source: La Radiologia Medica - July 15, 2020 Category: Radiology Source Type: research

Multimodality imaging in chronic heart failure
AbstractThe prevalence of heart failure (HF) is approximately 1 –2% of the adult population in developed countries, rising to  ≥ 10% among people over 70. The common symptoms of HF include shortness of breath, ankle swelling and fatigue, determined by a reduced cardiac output. Multimodality imaging is crucial to define HF etiology, determine prognosis an d guiding tailored treatments. Echocardiography is the most widely used imaging modality and maintains a pivotal role in the initial diagnostic work-up and in the follow-up of HF patients. Cardiac magnetic resonance (CMR) may support the morpho-funct...
Source: La Radiologia Medica - July 15, 2020 Category: Radiology Source Type: research

4D Flow when and how?
Abstract4D Flow is an emerging MR technique enabling three-dimensional and cardiac phase-resolved flowmetry with ECG-gated phase-contrast MRI that increased the speed of data acquisitions, accuracy and robustness. The method is promoting researches in areas that have not been fully addressed before in the cardiovascular system, such as flowmetry of the bloodstream across the valves, within the heart chambers, complexed flow dynamics such as vortex, helical or retrograde. Wall shear stress and other potential biomarkers derived from 4D Flow are known to be related to vascular wall diseases such as atherosclerosis. In this r...
Source: La Radiologia Medica - July 14, 2020 Category: Radiology Source Type: research

Impact of various iodine concentrations of iohexol and iodixanol contrast media on image reconstruction techniques in a vascular-specific contrast media phantom: quantitative and qualitative image quality assessment
AbstractPurposeThe aim of our study is to investigate the impact of iodine quantification on image reconstruction when employing a vascular-specific contrast media phantom with varying iodine concentrations.Materials and methodsA 30-cm phantom simulating arterial and venous blood vessel diameters was manufactured. Small (9  mm) and medium (12 mm) cylinders contained iodine concentrations from 10 to 100% while large (21 mm) cylinders were in quartiles from 25 to 100% diluted in blood equivalent medium. Each phantom was filled with either iohexol 350 mgI/mL (Group A) or iodixanol 320 mgI/mL (Group B) and then ...
Source: La Radiologia Medica - July 14, 2020 Category: Radiology Source Type: research

Breast imaging and cancer diagnosis during the COVID-19 pandemic: recommendations from the Italian College of Breast Radiologists by SIRM
AbstractThe Italian College of Breast Radiologists by the Italian Society of Medical Radiology (SIRM) provides recommendations for breast care provision and procedural prioritization during COVID-19 pandemic, being aware that medical decisions must be currently taken balancing patient ’s individual and community safety: (1) patients having a scheduled or to-be-scheduled appointment for in-depth diagnostic breast imaging or needle biopsy should confirm the appointment or obtain a new one; (2) patients who have suspicious symptoms of breast cancer (in particular: new onset palpab le nodule; skin or nipple retraction; o...
Source: La Radiologia Medica - July 12, 2020 Category: Radiology Source Type: research

Direct percutaneous embolization of aneurysm sac: a safe and effective procedure to treat post-EVAR type II endoleaks
ConclusionPercutaneous direct sac embolization using Onyx in combination or not with microcoils represents a safe and valid technique to solve post-EVAR type II endoleaks. (Source: La Radiologia Medica)
Source: La Radiologia Medica - July 12, 2020 Category: Radiology Source Type: research

Severe metrorrhagia in patients with advanced gynecologic cancer: endovascular treatment benefits in acute and chronic setting
ConclusionsEndovascular treatment of metrorrhagia in oncologic patients could be a valid therapeutic alternative, especially when in elderly patients with poor clinical conditions not suitable for surgery. A bilateral and superselective embolization using non-resorbable embolic agents should be performed, except for those cases in which there is infiltration of major vessels causing pseudoaneurysms or fistulas that require embolization. (Source: La Radiologia Medica)
Source: La Radiologia Medica - July 12, 2020 Category: Radiology Source Type: research

Preparation of a radiology department in an Italian hospital dedicated to COVID-19 patients
AbstractPreparedness for the ongoing coronavirus disease 2019 (COVID-19) and its spread in Italy called for setting up of adequately equipped and dedicated health facilities to manage sick patients while protecting healthcare workers, uninfected patients, and the community. In our country, in a short time span, the demand for critical care beds exceeded supply. A new sequestered hospital completely dedicated to intensive care (IC) for isolated COVID-19 patients needed to be designed, constructed, and deployed. Along with this new initiative, the new concept of “Pandemic Radiology Unit” was implemented as a prac...
Source: La Radiologia Medica - July 10, 2020 Category: Radiology Source Type: research