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The stroke east Saxony pilot project for organized post‐stroke care: a case–control study
ConclusionsOur pilot data suggest that organized post‐stroke care enhances achievement of secondary prevention goals. Its possible effect on stroke recurrence, long‐term disability, and quality of life is currently investigated in a prospective cohort study. The Stroke East Saxony Pilot Project for Organized Post‐Stroke Care was case–control study to explore the feasibility of a self‐developed standardized post‐stroke pathway and its impact on secondary stroke prevention and long‐term outcome in patients with acute stroke. These pilot data suggest that organized post‐stroke care enhances achievement of sec...
Source: Brain and Behavior - March 31, 2016 Category: Neurology Authors: Ulf Bodechtel, Kristian Barlinn, Uwe Helbig, Katrin Arnold, Timo Siepmann, Lars‐Peder Pallesen, Volker Puetz, Heinz Reichmann, Jochen Schmitt, Jessica Kepplinger Tags: Original Research Source Type: research

Antibiotic therapy for preventing infections in people with acute stroke.
CONCLUSIONS: Preventive antibiotics had no effect on functional outcome or mortality, but significantly reduced the risk of 'overall' infections. This reduction was driven mainly by prevention of urinary tract infection; no effect for pneumonia was found. PMID: 29355906 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - January 22, 2018 Category: General Medicine Authors: Vermeij JD, Westendorp WF, Dippel DW, van de Beek D, Nederkoorn PJ Tags: Cochrane Database Syst Rev Source Type: research

Neuroanatomy and severity of stroke in patients with type A aortic dissection
ConclusionsStrokes associated with ATAAD are severe at presentation resulting in significant disability. One in 10 strokes is due to LVO and potentially amenable to endovascular treatment. Heterogeneity in both location and etiology of stroke makes prevention challenging. Future trials may evaluate the role of early neuroimaging and simultaneous treatment of stroke given advancements in endovascular therapy.
Source: Journal of Cardiac Surgery - November 17, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Akash Fichadiya, Bijoy K. Menon, Alexander J. Gregory, Ericka Teleg, Jehangir J. Appoo Tags: ORIGINAL ARTICLE Source Type: research

Mechanical thrombectomy is efficacious in patients with pre ‐stroke moderate disability
ConclusionPatients with pre-stroke moderate disability may benefit from MT if they are appropriately selected. This may result in fewer patients requiring nursing home placement and less financial burden on the public health system, indicating significant savings are possible.
Source: Journal of Medical Imaging and Radiation Oncology - June 17, 2021 Category: Radiology Authors: Tara Nababan, Timothy J. Phillips, Graeme J. Hankey, Matthew T. Crockett, Albert Ho Yuen Chiu, Tejinder P. Singh, David Blacker, William McAuliffe Tags: Medical Imaging —Original Article Source Type: research

Anemia in young patients with ischaemic stroke
ConclusionAnemia on admission was associated with stroke in CeAD patients and with more severe strokes in both study samples. Moderate to severe anemia may predict unfavorable outcome.
Source: European Journal of Neurology - February 24, 2015 Category: Neurology Authors: L. Kellert, M. Kloss, A. Pezzini, T. M. Metso, A. J. Metso, S. Debette, D. Leys, V. Caso, V. Thijs, A. Bersano, E. Touzé, T. Tatlisumak, H. Gensicke, P. A. Lyrer, J. Bösel, S. T. Engelter, C. Grond‐Ginsbach, Tags: Original Article Source Type: research

Post‐stroke cognitive impairment is common even after successful clinical recovery
ConclusionsCognitive impairment as evaluated with a comprehensive neuropsychological assessment is prevalent in stroke survivors even with successful clinical recovery. Typically multiple domains and complex cognitive abilities are affected. MMSE is not sensitive in detecting these symptoms. Post‐stroke cognitive impairment is strongly related to poor functional outcome.
Source: European Journal of Neurology - June 4, 2015 Category: Neurology Authors: H. Jokinen, S. Melkas, R. Ylikoski, T. Pohjasvaara, M. Kaste, T. Erkinjuntti, M. Hietanen Tags: Original Article Source Type: research

Increase in Neutrophil after r ‐tPA Thrombolysis Predicts Poor Functional Outcome of Ischemic Stroke: A Longitudinal Study
ConclusionsDynamic increase in neutrophil after stroke significantly predicts 3‐month death or major disability in acute ischemic stroke patients receiving r‐tPA treatment.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - January 1, 2018 Category: Neurology Authors: Jijun Shi, Hao Peng, Shoujiang You, Yuanyuan Liu, Jiaping Xu, Yingying Xu, Huihui Liu, Rongfang Shi, Yongjun Cao, Chun ‐Feng Liu Tags: Original Article Source Type: research

Sex as predictor for achieved health outcomes and received care in ischemic stroke and intracerebral hemorrhage: a register-based study
ConclusionsA lower proportion of women had good functioning, a difference that remained in IS after adjustments for age, socioeconomic factors, living arrangements, ADL dependency, and stroke severity. The amount of received hospital care was lower for women after adjustments. Whether shorter hospital stay results in lower function or is a consequence of lower function cannot be elucidated. One-year survival was higher in men when no adjustments were made but lower after adjustments. This likely reflects that women were older at time of stroke, had more severe strokes, and more disability pre-stroke —factors that make a ...
Source: Biology of Sex Differences - March 7, 2018 Category: Biology Source Type: research

Early apixaban therapy after ischemic stroke in patients with atrial fibrillation
ConclusionsSymptomatic HT rates are likely to be low in randomized trials of DOAC initiation post-stroke. Recurrent ischemic stroke may be the major clinical outcome. These data may be used as expected event rates when calculating sample size requirements for future safety/efficacy trials of early versus late DOAC initiation after AF-related stroke.
Source: Journal of Neurology - January 3, 2021 Category: Neurology Source Type: research

Early rehabilitation after stroke: relationship between the heart rate variability and functional outcome
ConclusionsThe presence of autonomic cardiovascular dysregulation in patients with subacute stroke was associated with adverse functional outcome after the early post ‐stroke rehabilitation.
Source: ESC Heart Failure - July 29, 2020 Category: Cardiology Authors: Nadja Scherbakov, Anush Barkhudaryan, Nicole Ebner, Stephan Haehling, Stefan D. Anker, Michael Joebges, Wolfram Doehner Tags: Original Research Article Source Type: research

Impacts of Cigarette Smoking and Basilar Artery Flow on 1-year Recovery in 3-Month survivors of Intracranial Vertebrobasilar Artery Dissection-related Ischemic Stroke.
CONCLUSIONS: Our results suggest that adequate blood flow may be key to functional recovery after iVBDcaused PCS. Methods to improve blood flow and tissue perfusion after iVBD-caused PCS should be considered in the future clinical studies with the purpose to improve functional recovery in these patients. PMID: 27854084 [PubMed - in process]
Source: Acta Neurologica Taiwanica - November 19, 2016 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Total Small Vessel Disease Burden Predicts Functional Outcome in Patients With Acute Ischemic Stroke
Conclusion: Total SVD burden negatively associated with functional outcome at 3 months in patients with acute ischemic stroke and is superior to individual SVD feature in prediction of functional outcome. MRI-based assessment of total SVD burden is highly valuable in clinical management of stroke victims, and could help guide the allocation of resources to improve outcome.
Source: Frontiers in Neurology - August 5, 2019 Category: Neurology Source Type: research

Inter-hospital transfer for mechanical thrombectomy within the supraregional stroke network NEVAS
ConclusionWithin a telemedicine network stroke care can successfully be organized as only a minority of patients has to be transferred. Our data provide clinical evidence that all MT-eligible patients should be shipped with the fastest transportation modality as possible.
Source: Journal of Neurology - September 4, 2020 Category: Neurology Source Type: research

Results and functional outcomes of acute ischemic stroke patients who underwent mechanical thrombectomy admitted to intensive care unit
Conclusions The factors relating to a worse functional outcome were symptomatic hemorrhage transformation, lack of recanalization and complications during EVT. The factors relating to mortality were symptomatic hemorrhage and hydrocephalus. Distal flow was achieve in most cases with a low complication rate. Half of the patients presented functional independence one year after the stroke.
Source: Medicina Intensiva - May 30, 2018 Category: Intensive Care Source Type: research

Thrombolysis safety and effectiveness in acute ischemic stroke patients with pre-morbid disability
ConclusionPatients with mRS 2 and 3 may benefit from rt-PA with a moderate risk of sICH and mortality.
Source: Journal of Clinical Neuroscience - December 25, 2019 Category: Neuroscience Source Type: research

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