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Source: Heart, Lung and Circulation

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Total 240 results found since Jan 2013.

Atrial Fibrillation Clinics: The Way of the Future
In this edition of Heart, Lung and Circulation, Al-Busaidi et  al. [1] present the long-term outcomes of patients managed through their atrial fibrillation (AF) clinical pathway with early review at an outpatient AF clinic following discharge from the emergency department. The pathway was aimed at reducing unnecessary hospital admissions and improving adheren ce to guideline-based AF treatment. AF is the most common sustained arrhythmia and is associated with increased risk of cardiovascular morbidity, stroke, dementia, and death [2].
Source: Heart, Lung and Circulation - January 16, 2022 Category: Cardiology Authors: Juliana Kanawati, Saurabh Kumar Tags: Editorial Source Type: research

Chronic Rejection and Atherosclerosis in Post-Transplant Cardiovascular Mortality: Two Sides of the Same Coin
Cardiovascular disease (CVD) as defined by the American Heart Association includes ischaemic heart disease, stroke, heart failure and thromboembolism [1]. Solid organ transplantation is associated with an increased risk of CVD morbidity and mortality [2], a relationship which was first observed in the context of kidney transplantation by Foley in 1998 [3]. This manifests clinically as an increased rate of major adverse cardiovascular events (MACE), defined as the composite of cardiac death, non-fatal myocardial infarction, non-fatal stroke, unstable angina and heart failure [4,5].
Source: Heart, Lung and Circulation - November 27, 2021 Category: Cardiology Authors: Afolarin A. Otunla, Kumaran Shanmugarajah, Maria Lucia Madariaga, Alun H. Davies, Joseph Shalhoub Tags: Editorial Source Type: research

Neurological Complications in COVID-19 Patients With ECMO Support: A Systematic Review and Meta-Analysis
Patients with Coronavirus disease 2019 (COVID-19)-related acute respiratory disease (ARDS) increasingly receive extracorporeal membrane oxygenation (ECMO) support. While ECMO has been shown to increase risk of stroke, few studies have examined this association in COVID-19 patients.
Source: Heart, Lung and Circulation - October 28, 2021 Category: Cardiology Authors: Nivedha V. Kannapadi, Meghana Jami, Lavienraj Premraj, Eric W. Etchill, Katherine Giuliano, Errol L. Bush, Bo Soo Kim, Stella Seal, Glenn Whitman, Sung-Min Cho Tags: Original Article Source Type: research

Smooth Muscle Cell Molecular Underpinnings of Vascular Ageing
Arterial ageing assigns a key role to arterial stiffening in the continuum between healthy vascular ageing and the development and progression of hypertension, heart failure, kidney disease and stroke. Arterial stiffness is a major independent risk factor for cardiovascular complications causing isolated systolic hypertension and increased pulse pressure in the microvasculature of target organs. Vascular ageing causes chronic arterial inflammation and intimal-medial thickening through phenotypic changes in vascular cells and structural changes in the media.
Source: Heart, Lung and Circulation - September 29, 2021 Category: Cardiology Authors: Veronique Regnault, Alexandre Raoul, Celia Schellenberg, Patrick Lacolley Tags: Editorial Source Type: research

Antegrade Perfusion for Mini-Thoracotomy Mitral Valve Surgery in Patients with Atherosclerotic Burden
The relationship between retrograde arterial perfusion and stroke in patients with peripheral vascular disease has been widely documented. Antegrade arterial perfusion has been favoured as an alternative approach in less invasive mitral valve (MV) operations. We aimed to analyse our experience in patients with peripheral arterial disease undergoing MV surgery through a right mini-thoracotomy adopting antegrade arterial perfusion.
Source: Heart, Lung and Circulation - September 13, 2021 Category: Cardiology Authors: Cristina Barbero, Marco Pocar, Giovanni Marchetto, Erik Cura Stura, Claudia Calia, Massimo Boffini, Mauro Rinaldi, Davide Ricci Tags: Original Article Source Type: research

Atrial Septal Aneurysms – A Clinically Relevant Enigma?
Atrial septal aneurysms (ASAs) are often seen during routine cardiac imaging, though their clinical relevance has been poorly defined. The aneurysmal, and often mobile, inter-atrial septum is frequently associated with other clinically relevant structural cardiac abnormalities, particularly patent foramen ovale (PFO). Whilst ASAs have previously been considered an incidental finding, a well-endowed atrial septum provides more than visual interest, including insights into atrial function and intra-atrial pressures, and has important clinical implications in PFO-associated stroke, migraines, and arrhythmias.
Source: Heart, Lung and Circulation - September 7, 2021 Category: Cardiology Authors: Kenneth Cho, Michael Feneley, Cameron Holloway Tags: Review Source Type: research

Redo CABG: Where Every Ounce of Experience Matters Regardless of the Technique
In this issue of Heart, Lung and Circulation, Tzoumas et  al. [1] report A Meta-Analysis of Repeat Coronary Artery Bypass Grafting comparing Off-Pump to On-Pump Techniques in a Large Cohort of Patients. They concluded that off-pump redo coronary artery bypass graft (CABG) resulted in lower perioperative death and periprocedural complication rates, and th ere was no difference observed in perioperative stroke rates and long-term survival between the two techniques. However, we commend the authors for acknowledging that there were limitations to their conclusions, thus limiting generalisation of their findings.
Source: Heart, Lung and Circulation - July 6, 2021 Category: Cardiology Authors: Adam El-Gamel Tags: Editorial Source Type: research

Underusage of Oral Anticoagulation in Atrial Fibrillation: Can We Prevent More Strokes?
Atrial fibrillation (AF) is the most common sustained arrhythmia in Australia, affecting 2% of the population, and 6% of those over the age of 55 years [1]. The greatest contributor to morbidity and mortality in AF is its association with ischaemic stroke [2]. AF increases the risk of cardioembolic stroke five-fold, with an annual incidence of up to 7% [3]. There have been several validated tools developed to help individualise stroke risk, such as the CHADS2 [4], CHA2DS2-VASc [5], and more recently the CHA2DS2-VA score [6], all of which require the input of several vascular risk factors.
Source: Heart, Lung and Circulation - June 2, 2021 Category: Cardiology Authors: Karan Rao, Ravinay Bhindi Tags: Editorial Source Type: research

Are Digital Health Services the Key to Bridging the Gap in Medication Adherence and Optimisation?
Strong adherence to medications for the secondary prevention of cardiovascular disease (CVD), (e.g., lipid-lowering therapy, antihypertensives, antiplatelets), can reduce the risk of adverse cardiovascular events such as myocardial infarction and stroke [1]. Yet, poor adherence rates to therapies of about 50% are common among patients with chronic diseases [2]. There are various reasons for this large gap which include poor patient health literacy and incomplete/out-dated medication lists in electronic health records.
Source: Heart, Lung and Circulation - May 5, 2021 Category: Cardiology Authors: Harry Klimis, Clara K. Chow Tags: Editorial Source Type: research

Stroke Risk in Adults With Atrial Fibrillation According to Sex
Stroke risk stratification is an important clinical process in atrial fibrillation (AF) management [1]. In the early 2000s, the CHADS2 score was developed to calculate stroke risk and was recommended in both American and European AF management guidelines. In 2012, the CHA2DS2VASc score became the recommended tool in the ESC guidelines to assess stroke risk, as the CHA2DS2VASc score was more discriminatory at identifying patients who were truly at low risk and therefore did not require oral anticoagulation (OAC) treatment —a very important change in our conceptualisation of how these scores should be used in clinical practice.
Source: Heart, Lung and Circulation - April 22, 2021 Category: Cardiology Authors: Caleb Ferguson, Nicole Lowres, Ben Freedman Tags: Editorial Source Type: research

Reality is Far From the Guidelines, When  it Comes to Stroke Prevention in Atrial Fibrillation
In this issue of Heart, Lung and Circulation, Hutchens et  al. report the trends of oral anticoagulant use and antiplatelet use in patients with atrial fibrillation (AF) [1].
Source: Heart, Lung and Circulation - April 22, 2021 Category: Cardiology Authors: Kathryn D. Tiver, Jing Quah, Dhani Dharmaprani, Anand N. Ganesan Tags: Editorial Source Type: research

Predictors of New-Onset Atrial Tachyarrhythmias After Transcatheter Atrial Septal Defect Closure in Adults
This study investigated unknown risk factors for the development of new-onset ATA after transcatheter ASD closure in patients without a history of ATA.
Source: Heart, Lung and Circulation - April 13, 2021 Category: Cardiology Authors: Kotaro Miura, Mai Kimura, Atsushi Anzai, Takahide Arai, Takashi Kawakami, Shinsuke Yuasa, Kentaro Hayashida, Jin Endo, Hikaru Tsuruta, Yuji Itabashi, Akio Kawamura, Keiichi Fukuda, Hideaki Kanazawa Tags: Original Article Source Type: research

Risk of Stroke in Atrial Fibrillation According to Sex in Patients Aged Younger Than 75 Years: A Large-Scale, Observational Study Using Real-World Data
This study aimed to clarify the effects of a sex difference on the risk of ischaemic stroke in patients with atrial fibrillation (AF).
Source: Heart, Lung and Circulation - January 16, 2021 Category: Cardiology Authors: Toshiki Maeda, Takumi Nishi, Shunsuke Funakoshi, Kazuhiro Tada, Masayoshi Tsuji, Atsushi Satoh, Miki Kawazoe, Chikara Yoshimura, Hisatomi Arima Tags: Original Article Source Type: research

Elevated Apolipoprotein B/A-1 Ratio is Associated With an Increased Risk of Aortic Stenosis: Experience From the AMORIS Cohort
This study investigated whether an elevated apolipoprotein (apo)B/apoA-1 ratio was associated with an increased risk of AS and if this association was influenced by a history of a major adverse cardiovascular event (MACE) defined as stroke, myocardial infarction or revascularisation.
Source: Heart, Lung and Circulation - January 15, 2021 Category: Cardiology Authors: Torbj örn Ivert, Niklas Hammar, Mats Talbäck, Håkan Malmström, Karin Leander, Göran Walldius Tags: Original Article Source Type: research

828 Factors Influencing Periprocedural Stroke at the Time of Transcatheter Aortic Valve Implantation in the Era of Cerebral Protection
To compare patient factors in those who suffer periprocedural stroke at the time of transcatheter aortic valve implantation (TAVI), with a view to identifying patients who may benefit from provisional cerebral protection device use.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: K. Kearney, H. Kempton, K. Jones, J. Carroll, T. Meredith, N. Bart, A. Arrigiada, D. Baron, D. Muller, D. Roy Source Type: research