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Source: Heart, Lung and Circulation

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Total 240 results found since Jan 2013.

Percutaneous Left Atrial Appendage Occlusion with a Watchman Device Following Recurrent Stroke on Warfarin and Rivaroxaban in Patient with Paroxysmal Atrial Fibrillation
We present the case of a 66 year-old male with paroxysmal atrial fibrillation who experienced recurrent stroke despite treatment with warfarin initially, and rivaroxaban subsequently. After excluding non-cardioembolic causes of recurrent stroke, we proceeded with percutaneous occlusion of the LAA with a Watchman device. Nine months post-procedure he has not experienced recurrence of neurological symptoms. Our case provides anectodal evidence that catheter-based LAA occlusion can be beneficial in secondary stroke prevention where oral anticoagulation has been problematic.
Source: Heart, Lung and Circulation - September 30, 2013 Category: Cardiology Authors: Roberto Spina, Rajesh Subbiah, Romesh Markus, Brendan Gunalingam Tags: Brief Communications Source Type: research

Amplatzer PFO Occluder Device may Prevent Recurrent Stroke in Patients with Patent Foramen Ovale and Cryptogenic Stroke: A Meta-Analysis of Randomised Trials
Conclusion: The closure of PFO with Amplatzer PFO occluder device was associated with significant reduction in recurrent strokes in patients with cryptogenic stroke and patent foramen ovale. The better outcome in prevention of secondary stroke in patients with cryptogenic stroke and PFO may be associated with type of closure device used.
Source: Heart, Lung and Circulation - February 4, 2014 Category: Cardiology Authors: Anil Pandit, Madan Raj Aryal, Aashrayata Aryal Pandit, Leena Jalota, Sudheer Kantharajpur, Fayaz A. Hakim, Howard R. Lee Tags: Reviews Source Type: research

Is Atrial Fibrillation a Stroke Risk Factor or Risk Marker? An Appraisal Using the Bradford Hill Framework for Causality
Atrial fibrillation (AF) is strongly associated with stroke risk but association on its own does not necessarily imply causality. Is AF a cause (risk factor) of stroke? Would treatment that reduces AF burden also reduce the burden of stroke? Or, perhaps, AF is a risk marker associated with a vascular syndrome in which there is co-existing atrial structural and electrical remodelling that results in the clinical manifestation of AF and the risk of stroke in parallel. A number of recent studies appear to detach AF as a direct cause of stroke.
Source: Heart, Lung and Circulation - August 13, 2019 Category: Cardiology Authors: V. Malik, A.N. Ganesan, J.B. Selvanayagam, D.P. Chew, A.D. McGavigan Tags: Review Source Type: research

Is Transcatheter Closure Better than Medical Therapy for Cryptogenic Stroke with Patent Foramen Ovale? A Meta-analysis of Randomised Trials
Conclusions: In patients with cryptogenic stroke or TIA who had a patent foramen ovale, closure with a device does not confer an advantage over medical therapy and is associated with adverse events like major vascular complication and atrial fibrillation.
Source: Heart, Lung and Circulation - September 13, 2013 Category: Cardiology Authors: Vinayak Nagaraja, Jwalant Raval, Guy D. Eslick, David Burgess, A. Robert Denniss Tags: Reviews Source Type: research

Who Gets Stroke Prevention? Stroke Prevention in Atrial Fibrillation Patients in the Inpatient Setting.
Current guidelines strongly recommend antithrombotic therapy, particularly warfarin, for stroke prevention in atrial fibrillation (AF) patients at high risk of stroke. Despite this, use of these medications is far from optimal. The aim of this study was to describe the use of stroke prevention medication in inpatients and identify factors associated with prescription in one local health district in Sydney, Australia.
Source: Heart, Lung and Circulation - December 23, 2014 Category: Cardiology Authors: Robyn Gallagher, Kellie Roach, Leonie Sadler, Julie Belshaw, Ann Kirkness, Ling Zhang, Ross Proctor, Lis Neubeck Source Type: research

Comparison of Echocardiographic Parameters of Left Atrial and Ventricular Function between Young Stroke vs Lone Atrial Fibrillation vs Healthy Controls
Background: Stroke is one of Australia's leading causes of morbidity and mortality with a significant percentage classified as cryptogenic. The nature and aetiology of cryptogenic stroke remains elusive, with a proportion believed to be cardio-embolic secondary to subclinical paroxysmal atrial fibrillation (AF). We aim to gain mechanistic insights into the pathophysiology of cryptogenic stroke in the young by comparing cardiac structural and functional differences in patients with young stroke, lone AF and healthy controls.
Source: Heart, Lung and Circulation - June 23, 2019 Category: Cardiology Authors: A. Bhat, S. Khanna, H. Chen, G. Gan, R. MacIntyre, T. Tan Tags: 254 Source Type: research

Stroke Recurrence in Embolic Stroke of Undetermined Source Without Atrial Fibrillation on Invasive Cardiac Monitoring
This study investigated the predictors and prognosis of recurrent stroke in ESUS without AF on ICM.
Source: Heart, Lung and Circulation - June 6, 2023 Category: Cardiology Authors: Eugene S.J. Tan, Jhobeleen de Leon, Elaine Boey, Howe-Keat Chin, Kian-Hui Ho, Shana Aguirre, Ming-Gin Sim, Swee-Chong Seow, Vijay K. Sharma, Pipin Kojodjojo Tags: Original Article Source Type: research

Influencing Factors for Early Acute Cerebrovascular Accidents in Patients with Stroke History following Off-pump Coronary Artery Bypass Grafting
Conclusions: This study indicated that patients with severe bilateral carotid stenosis, the left ventricular ejection fraction ≤35%, the postoperative acute myocardial infarction, postoperative atrial fibrillation and postoperative hypotension were more likely to suffer from early acute cerebrovascular accidents when they received OPCAB. Application of Enclose® II proximal anastomotic device may decrease the incidence of early acute cerebrovascular accidents during OPCAB.
Source: Heart, Lung and Circulation - February 10, 2014 Category: Cardiology Authors: Bin Wang, Ming Jia, Shijie Jia, Jiuhe Wan, Xiao Zhou, Zhimin Luo, Ye Zhou, Jianqun Zhang Tags: Original Articles Source Type: research

Dealing With the Left Atrial Appendage for Stroke Prevention: Devices and Decision-Making
Left atrial appendage (LAA) device occlusion represents a major evolution in stroke prevention for atrial fibrillation (AF). Left atrial appendage device occlusion is now a proven strategy which provides long-term thromboembolic stroke prevention for patients with non-rheumatic AF. Evidence supports its benefit as an alternative to long-term anticoagulation while mitigating long-term bleeding risks and improving cardiovascular mortality. The therapy offers expanded options to physicians and patients negotiating stroke prevention (both primary and secondary prevention), but a good understanding of the risks and benefits is ...
Source: Heart, Lung and Circulation - May 16, 2017 Category: Cardiology Authors: Karen P. Phillips, Vince Paul Source Type: research

Stroke Risk Factors and Outcomes in Indigenous Verse Non-Indigenous Australians
Background: Stroke risk factors are well known, but there is little data on the prevalence of stroke risk factors in Indigenous Australian cohorts. We aim to assess the risk factors and the outcomes after stroke and compare these in Indigenous and non-Indigenous Australians presenting with acute strokes to the Wagga Wagga Rural Referral Hospital.
Source: Heart, Lung and Circulation - May 24, 2019 Category: Cardiology Authors: Angela Dos Santos, Katherine Mohr, Martin Jude, Neil Simon, Candice Delcourt Tags: P20 Source Type: research

Predicted Impact of Recent Patent Foramen Ovale Closure Trials on Management of Cryptogenic Stroke
Background: The indication for percutaneous closure of patent foramen ovale (PFO) has recently changed, following evidence that closure is superior to medical treatment alone in preventing recurrent stroke in cryptogenic stroke patients aged ≤60 years. We aimed to determine the impact of updated criteria on the management of stroke or transient ischemic attack (TIA) at our institution.
Source: Heart, Lung and Circulation - June 23, 2019 Category: Cardiology Authors: P. Trevella, L. Sanders, D. Jin, J. Gutman, MacA. Isaac, S. Palmer Tags: 667 Source Type: research

414 The Diagnostic Value of Inpatient Transthoracic Echocardiography for Stroke and TIA
Australian guidelines for ischaemic stroke recommend echocardiography for select patients in whom stroke aetiology is unclear after initial investigations.1 We sought to identify whether inpatient echocardiograms for investigation of stroke/TIA aetiology were appropriately utilised according to this recommendation.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: M. Maffey, S. Nguyen, S. Wahi Source Type: research

Stroke Risk in Adults With Atrial Fibrillation According to Sex
Stroke risk stratification is an important clinical process in atrial fibrillation (AF) management [1]. In the early 2000s, the CHADS2 score was developed to calculate stroke risk and was recommended in both American and European AF management guidelines. In 2012, the CHA2DS2VASc score became the recommended tool in the ESC guidelines to assess stroke risk, as the CHA2DS2VASc score was more discriminatory at identifying patients who were truly at low risk and therefore did not require oral anticoagulation (OAC) treatment —a very important change in our conceptualisation of how these scores should be used in clinical practice.
Source: Heart, Lung and Circulation - April 22, 2021 Category: Cardiology Authors: Caleb Ferguson, Nicole Lowres, Ben Freedman Tags: Editorial Source Type: research

The Association Between Sex Hormones and Incident Stroke
There is a distinct difference in both the incidence and outcomes of stroke between men and women. Women have a higher lifetime risk of stroke than men and are more likely to have a more severe post-stroke deficit. The underlying mechanisms driving this remain unclear.
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: M. Cook, B. Tucker, S. Patel, K. Rye, K. Ong Source Type: research

Relationship between Atherosclerotic Risk Factors and Aortic Plaques in Patients with First-ever Ischaemic Stroke
Aortic plaque is considered a risk factor of ischaemic stroke, and both ulceration and plaque thickness are considered important. However, the relative importance of aortic plaque and carotid plaque remains unclear. The purpose of this study is to clarify the relation between aortic and carotid plaque lesions and atherosclerotic risk factors in patients with acute ischaemic stroke.
Source: Heart, Lung and Circulation - June 5, 2014 Category: Cardiology Authors: Atsushi Mizuma, Chikage Kijima, Kazuyuki Iijima, Yoshiaki Goto, Kazunari Honma, Takashi Yasuda, Kentaro Tokuoka, Yasuhisa Kitagawa, Shunya Takizawa Source Type: research