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Source: Heart, Lung and Circulation

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Total 240 results found since Jan 2013.

Effect of Posterior Pericardiotomy on the Incidence of Postoperative Atrial Fibrillation in 1000 Consecutive Isolated CABG
Purpose: Postoperative atrial fibrillation (POAF) is the most common arrhythmia and morbidity after cardiac surgery and is associated with prolonged hospital stay, stroke and increased costs. At the Royal Hobart Hospital, one of the two surgeons routinely performed posterior pericardiotomy for patients undergoing coronary artery bypass grafting (CABG). We took this opportunity to review risk factors associated with postoperative atrial fibrillation and in particular if posterior pericardiotomy reduces the incidence of postoperative atrial fibrillation.
Source: Heart, Lung and Circulation - June 17, 2016 Category: Cardiology Authors: Siew Simg Christine Goh, Gary Hamilton, Rose Stewart, Sameer Thakur, Mark Murton, Ashutosh Hardikar Source Type: research

Therapeutic Prospects of Gene Therapy for Atrial Fibrillation
Atrial Fibrillation (AF) is one of the most common types of cardiac arrhythmias experienced in clinical practice, increasing the risk of stroke, dementia, myocardial infarction and death. Currently available options for the treatment of AF use either pharmacological agents or catheter-based ablation therapies to restore sinus rhythm or control the ventricular response rate. These current treatment options are suboptimal at best, motivating research into discovering more effective and innovative ways to treat AF.
Source: Heart, Lung and Circulation - May 11, 2016 Category: Cardiology Authors: Melad Farraha, James J.H. Chong, Eddy Kizana Source Type: research

Efficacy and Safety of Percutaneous Left Atrial Appendage Occlusion for Stroke Prevention in Nonvalvular Atrial Fibrillation: A Meta-analysis of Contemporary Studies
Percutaneous left atrial appendage (LAA) occlusion has emerged as an important treatment for patients with nonvalvular atrial fibrillation (NVAF) who are at high stroke risk and have contraindications for anticoagulation. However, literature about the efficacy and safety of LAA occlusion is minimal to date. We performed a meta-analysis to assess the rates of stroke events and adverse events for patients treated with occlusion devices.
Source: Heart, Lung and Circulation - May 1, 2016 Category: Cardiology Authors: Haiyan Xu, Xiongwei Xie, Bingjian Wang, Shuren Ma, Fang Wang Tags: Original Article Source Type: research

Efficacy and Safety of Percutaneous Left Atrial Appendage Occlusion for Stroke Prevention in Nonvalvular Atrial Fibrillation: A meta-analysis of contemporary studies
Percutaneous left atrial appendage (LAA) occlusion has emerged as an important treatment for patients with nonvalvular atrial fibrillation (NVAF) who are at high stroke risk and have contraindications for anticoagulation. However, literature about the efficacy and safety of LAA occlusion is minimal to date. We performed a meta-analysis to assess the rates of stroke events and adverse events for patients treated with occlusion devices.
Source: Heart, Lung and Circulation - May 1, 2016 Category: Cardiology Authors: Haiyan Xu, Xiongwei Xie, Bingjian Wang, Shuren Ma, Fang Wang Source Type: research

Endovascular Therapy Proven for Stroke – Finally!
Cardiologists often remark that the field of ischaemic stroke follows in the footsteps of cardiology, just one to two decades later. In the case of endovascular reperfusion therapies this certainly seems to have been the case but there are now multiple positive randomised trials establishing the benefit of mechanical thrombectomy over and above standard care, which included intravenous alteplase in most cases. We will outline the new evidence, contrast the recent trials with the earlier negative studies and discuss some important differences between acute myocardial infarction and ischaemic stroke and the techniques required to treat them.
Source: Heart, Lung and Circulation - April 21, 2015 Category: Cardiology Authors: Bruce C.V. Campbell, Peter J. Mitchell, Richard J. Dowling, Bernard Yan, Geoffrey A. Donnan, Stephen M. Davis Tags: Editorial Source Type: research

Who Gets Stroke Prevention? Stroke Prevention in Atrial Fibrillation Patients in the Inpatient Setting.
Current guidelines strongly recommend antithrombotic therapy, particularly warfarin, for stroke prevention in atrial fibrillation (AF) patients at high risk of stroke. Despite this, use of these medications is far from optimal. The aim of this study was to describe the use of stroke prevention medication in inpatients and identify factors associated with prescription in one local health district in Sydney, Australia.
Source: Heart, Lung and Circulation - December 23, 2014 Category: Cardiology Authors: Robyn Gallagher, Kellie Roach, Leonie Sadler, Julie Belshaw, Ann Kirkness, Ling Zhang, Ross Proctor, Lis Neubeck Source Type: research

Progress on Salt Reduction in the Pacific Islands: From Strategies to Action
The objective of this analysis was to review progress to date and identify regional actions needed to support PICs and ensure they achieve the global target to reduce population salt intake by 30% by 2025.
Source: Heart, Lung and Circulation - December 9, 2014 Category: Cardiology Authors: Anthea Christoforou, Wendy Snowdon, Nevalyn Laesango, Seta Vatucawaqa, Daniel Lamar, Lawrence Alam, Kippier Lippwe, Iemaima Lise Havea, Karen Tairea, Peter Hoejskov, Temo Waqanivalu, Jacqui Webster Source Type: research

Dual Versus Single Antiplatelet Therapy in Patients Undergoing Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-analysis
Although dual antiplatelet therapy (DAPT) with clopidogrel and aspirin is a widely accepted strategy in patients undergoing transcatheter aortic valve replacement (TAVR), this approach is not evidence based. We therefore sought to systematically review the current evidence for this practice in terms of 30-day outcome looking at stroke, MI, bleeding, and death.
Source: Heart, Lung and Circulation - September 18, 2014 Category: Cardiology Authors: Madan Raj Aryal, Paras Karmacharya, Anil Pandit, Fayaz Hakim, Ranjan Pathak, Naba Raj Mainali, Anene Ukaigwe, Maryam Mahmood, Madan Badal, F. David Fortuin Tags: Original Article Source Type: research

Anaortic OPCAB for High-risk Patients
We read with interest the article by Wang and Colleagues [1]. They describe a high incidence of stroke in patients undergoing OPCAB with history of previous stroke. A number of risk factors for peri-operative stroke are identified and the use of an occlusive proximal anastomotic device is described as protective.
Source: Heart, Lung and Circulation - August 22, 2014 Category: Cardiology Authors: J. James B. Edelman, Michael P. Vallely Tags: Letter to the Editor Source Type: research

Prevalence of Vitamin D Deficiency Prior to Cardiothoracic Surgery
Vitamin D deficiency is one of the most common chronic medical conditions in the world and also prevalent in Australia. A growing body of evidence suggests that low vitamin D also has adverse effects on cardiovascular health, including coronary risk factors and adverse cardiovascular outcomes such as myocardial infarction, cardiac failure and stroke.There is some evidence suggesting that a greater proportion of people with cardiovascular disease have low vitamin D compared to the general population.
Source: Heart, Lung and Circulation - July 1, 2014 Category: Cardiology Authors: Lesley A. Braun, Ondine Spitzer, Bianca Levkovich, Michael Bailey, Cathy Stanguts, Lisa Hose, Franklin Rosenfeldt Source Type: research

Relationship between Atherosclerotic Risk Factors and Aortic Plaques in Patients with First-ever Ischaemic Stroke
Aortic plaque is considered a risk factor of ischaemic stroke, and both ulceration and plaque thickness are considered important. However, the relative importance of aortic plaque and carotid plaque remains unclear. The purpose of this study is to clarify the relation between aortic and carotid plaque lesions and atherosclerotic risk factors in patients with acute ischaemic stroke.
Source: Heart, Lung and Circulation - June 5, 2014 Category: Cardiology Authors: Atsushi Mizuma, Chikage Kijima, Kazuyuki Iijima, Yoshiaki Goto, Kazunari Honma, Takashi Yasuda, Kentaro Tokuoka, Yasuhisa Kitagawa, Shunya Takizawa Tags: Original article Source Type: research

Diagnosis, Prognosis and Therapeutic Role of Circulating miRNAs in Cardiovascular Diseases
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the world. Although much progress has been made for cardiovascular diseases in diagnosis, treatment and prognosis during the past two decades, the clinical need for a novel diagnostic biomarker and new therapeutic interventions to decrease the cardiovascular disease incidence is ongoing.MicroRNAs (miRNAs) are endogenous, small (∼22 nucleotides), single-stranded, non-coding RNAs that regulate gene expression and are detectable in whole blood, serum, plasma, urine and other body fluids in a highly stable form. Accumulating evidence suggests t...
Source: Heart, Lung and Circulation - April 10, 2014 Category: Cardiology Authors: Ali Sheikh Md Sayed, Ke Xia, Umme Salma, Tianlun Yang, Jun Peng Tags: Reviews Source Type: research