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Source: Heart, Lung and Circulation

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Total 240 results found since Jan 2013.

Cardiac Surgery in Indigenous Australians: Early Onset Cardiac Disease with follow-up Challenges
Conclusions: The mean age of 52 years at which Indigenous patients have cardiac surgery is significantly low compared to non-Indigenous patients. Indigenous patients have multiple risk factors for cardiac disease and with a large number requiring emergency surgery. Although surgical outcome in the short term is favourable, a large number of patients are lost to follow-up. The use of mechanical valve and warfarin should be individualised. Strategic post-operative follow-up mechanisms are needed to address these issues.
Source: Heart, Lung and Circulation - February 24, 2014 Category: Cardiology Authors: M.P. Matebele, S. Rohde, A. Clarke, J.F. Fraser Tags: Original Articles Source Type: research

Percutaneous Transcatheter Left Atrial Appendage Closure Devices: Role in the Long-Term Management of Atrial Fibrillation
Conclusions: Percutaneous left atrial appendage occlusion is an exciting and novel therapy of stroke prevention in atrial fibrillation. Whilst further trials and long-term data are required prior to widespread implementation of this procedure, trials so far have highlighted the clinical efficacy of the procedure.
Source: Heart, Lung and Circulation - February 13, 2014 Category: Cardiology Authors: Chieh Howe (Gary) Gan, Aditya Bhat, Lloyd Davis, A. Robert Denniss Tags: Reviews Source Type: research

Influencing Factors for Early Acute Cerebrovascular Accidents in Patients with Stroke History following Off-pump Coronary Artery Bypass Grafting
Conclusions: This study indicated that patients with severe bilateral carotid stenosis, the left ventricular ejection fraction ≤35%, the postoperative acute myocardial infarction, postoperative atrial fibrillation and postoperative hypotension were more likely to suffer from early acute cerebrovascular accidents when they received OPCAB. Application of Enclose® II proximal anastomotic device may decrease the incidence of early acute cerebrovascular accidents during OPCAB.
Source: Heart, Lung and Circulation - February 10, 2014 Category: Cardiology Authors: Bin Wang, Ming Jia, Shijie Jia, Jiuhe Wan, Xiao Zhou, Zhimin Luo, Ye Zhou, Jianqun Zhang Tags: Original Articles Source Type: research

Amplatzer PFO Occluder Device may Prevent Recurrent Stroke in Patients with Patent Foramen Ovale and Cryptogenic Stroke: A Meta-Analysis of Randomised Trials
Conclusion: The closure of PFO with Amplatzer PFO occluder device was associated with significant reduction in recurrent strokes in patients with cryptogenic stroke and patent foramen ovale. The better outcome in prevention of secondary stroke in patients with cryptogenic stroke and PFO may be associated with type of closure device used.
Source: Heart, Lung and Circulation - February 4, 2014 Category: Cardiology Authors: Anil Pandit, Madan Raj Aryal, Aashrayata Aryal Pandit, Leena Jalota, Sudheer Kantharajpur, Fayaz A. Hakim, Howard R. Lee Tags: Reviews Source Type: research

Antiplatelet versus Antithrombotic Therapy After Bioprosthetic Aortic Valve Replacement
Background: Aortic valve replacement with bioprosthesis is one of the commonest operations in cardiac surgery. Despite its frequency and a large number of patients post biological AVR there is no agreement on the best postoperative management of these patients in terms of reduction of cardiovascular death and prevention of thromboembolic complications short- and long-term (stroke, myocardial infarction, peripheral vascular thromboembolic events) maintaining low incidence of haemorrhagic complications. The main question is whether antiplatelet or antithrombotic therapy is more beneficial for the patients.
Source: Heart, Lung and Circulation - January 1, 2014 Category: Cardiology Authors: Sergei Mitnovetski, Tirone E. David Tags: Abstracts Source Type: research

The Influence of Preoperative Anaemia on Postoperative Outcomes in First Time Elective Isolated Aortic Valve Replacement Surgery in the Prince Charles Hospital: A Ten-Year Review
This study aims to assess the relationship between preoperative anaemia and postoperative clinical outcomes in elective isolated aortic valve replacement (AVR) patients from The Prince Charles Hospital (TPCH).
Source: Heart, Lung and Circulation - January 1, 2014 Category: Cardiology Authors: Y. Ranawaka, C. Villanueva, B. Pearse, S. Gabriel, J. McGree, L. Nair, H. Thompson, D. Wall, P. Tesar Tags: Abstracts Source Type: research

Hybrid Approach for Ablation of Atrial Fibrillation—A Systematic Review of the Literature
Introduction: The management of atrial fibrillation (AF) is one of ongoing importance with rates as high as up to 10% in selected populations . AF results in increasing hospitalisation due to palipitations, heart failure, syncope or stroke. Catheter ablation has been increasingly utilised as an effective rhythm control strategy; however, the durability of the results have been varied. In this context, a new strategy of a hybrid approach, combining surgical and catheter ablation, is emerging. In this systematic review, we aim to review the literature purporting the use of the hybrid approach.
Source: Heart, Lung and Circulation - January 1, 2014 Category: Cardiology Authors: J.A. Varzaly, A.G. Brooks, D.H. Lau, J. Edwards, R.G. Stuklis, P. Sanders, M. Worthington Tags: Abstracts Source Type: research

Transapical Aortic Valve Implantation—An Australian Experience
Conclusion: Good short-term outcomes and low or zero mortality are achievable with transapical TAVI at an Australian institution.
Source: Heart, Lung and Circulation - December 6, 2013 Category: Cardiology Authors: Michael Seco, Gonzalo Martinez, Paul G. Bannon, Bruce L. Cartwright, Mark Adams, Martin Ng, Michael K. Wilson, Michael P. Vallely Tags: Original Articles Source Type: research

The Current and Future Role of the Novel Oral Anticoagulants—Indications Beyond Atrial Fibrillation
Abstract: The direct thrombin inhibitors and Factor-Xa inhibitors are novel oral anticoagulants which are gaining rapid acceptance not only as alternatives to warfarin, but also as recommended first line agents for use as stroke prophylaxis in patients with non-valvular atrial fibrillation.There are, however, other patient settings in which anticoagulation is either indicated or has a potential role. Warfarin is still the predominant anticoagulant used for the treatment and prevention of venous thromboembolic events including deep vein thrombosis and pulmonary embolism as well as in patients with mechanical prosthetic hear...
Source: Heart, Lung and Circulation - November 1, 2013 Category: Cardiology Authors: Adam Lee, Rohan Rajaratnam Tags: Reviews Source Type: research

Percutaneous Left Atrial Appendage Occlusion with a Watchman Device Following Recurrent Stroke on Warfarin and Rivaroxaban in Patient with Paroxysmal Atrial Fibrillation
We present the case of a 66 year-old male with paroxysmal atrial fibrillation who experienced recurrent stroke despite treatment with warfarin initially, and rivaroxaban subsequently. After excluding non-cardioembolic causes of recurrent stroke, we proceeded with percutaneous occlusion of the LAA with a Watchman device. Nine months post-procedure he has not experienced recurrence of neurological symptoms. Our case provides anectodal evidence that catheter-based LAA occlusion can be beneficial in secondary stroke prevention where oral anticoagulation has been problematic.
Source: Heart, Lung and Circulation - September 30, 2013 Category: Cardiology Authors: Roberto Spina, Rajesh Subbiah, Romesh Markus, Brendan Gunalingam Tags: Brief Communications Source Type: research

Is Transcatheter Closure Better than Medical Therapy for Cryptogenic Stroke with Patent Foramen Ovale? A Meta-analysis of Randomised Trials
Conclusions: In patients with cryptogenic stroke or TIA who had a patent foramen ovale, closure with a device does not confer an advantage over medical therapy and is associated with adverse events like major vascular complication and atrial fibrillation.
Source: Heart, Lung and Circulation - September 13, 2013 Category: Cardiology Authors: Vinayak Nagaraja, Jwalant Raval, Guy D. Eslick, David Burgess, A. Robert Denniss Tags: Reviews Source Type: research

Surgical Aortic Valve Replacement in Very Elderly Patients Aged 80 Years and Over: Evaluation of Early Clinical Outcomes
Background: An increasing number of very elderly patients aged ≥80 years will require aortic valve replacement (AVR) for severe aortic stenosis (AS). Many are classified as high-risk surgical candidates. Transcatheter aortic valve implantation (TAVI) has been proposed as an alternative to surgical AVR (SAVR) for high-risk patients. We evaluated early clinical outcomes of very elderly patients undergoing SAVR to optimise TAVI candidate selection.Methods: We conducted a retrospective case review of 132 consecutive patients aged ≥80 years undergoing isolated SAVR (49 patients) or combined SAVR/CABG (83 patients) during Fe...
Source: Heart, Lung and Circulation - September 9, 2013 Category: Cardiology Authors: Edwin Ho, Manu N. Mathur, Peter W. Brady, David Marshman, Russell J. Brereton, Donald E. Ross, Ravinay Bhindi, Peter S. Hansen Tags: ORIGINAL ARTICLES Source Type: research

The Effect of Optimising Cerebral Tissue Oxygen Saturation on Markers of Neurological Injury during Coronary Artery Bypass Graft Surgery
Background: Surgical revascularisation of the coronary arteries is a cornerstone of cardiothoracic surgery. Advanced age and the incidence of preoperative co-morbidity in patients presenting for coronary artery bypass graft surgery increases the potential for stroke and other perioperative outcomes. It is hypothesised that by using interventions during cardiac surgery to improve cerebral oxygenation, the risk of patients enduring adverse neurological outcomes would be reduced.Methods: Forty patients (mean age 55.3, standard deviation 9.74 and range from 39 to 72 years) undergoing on-pump coronary artery bypass graft surger...
Source: Heart, Lung and Circulation - August 2, 2013 Category: Cardiology Authors: Yakeen Harilall, Jamila Kathoon Adam, Bruce Mclure Biccard, Anu Reddi Tags: Original Articles Source Type: research

Anaortic Off-Pump Coronary Artery Bypass Grafting in the Elderly and Very Elderly
Conclusions: OPCAB is associated with low rates of 30-day mortality and peri-operative stroke in this elderly and very elderly patient cohort. Anaortic OPCAB can provide excellent short-term post-operative outcomes and may give the elderly and very elderly population the opportunity to benefit from surgical coronary revascularisation.
Source: Heart, Lung and Circulation - July 8, 2013 Category: Cardiology Authors: Edward A. Cooper, J. James B. Edelman, Deborah Black, R. John Brereton, Donald E. Ross, Paul G. Bannon, Michael K. Wilson, Michael P. Vallely Tags: Original Articles Source Type: research

Does Local Data Support RE-LY?—A One Year Case Series Looking at Major Bleeds on Vitamin K Antagonists Prescribed for Non-valvular AF
Introduction: The RE-LY trial showed that Dabigatran was non-inferior in stroke or systemic embolism prevention to Warfarin . Life threatening bleeding was less for the 110mg dose and similar for the 150mg dose to Warfarin .
Source: Heart, Lung and Circulation - June 24, 2013 Category: Cardiology Authors: V. Mathavan, C. Nunn Tags: Abstracts Source Type: research