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Source: Heart, Lung and Circulation

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Total 240 results found since Jan 2013.

Multidisciplinary Assessment in Optimising Results of Percutaneous Patent Foramen Ovale Closure
Percutaneous patent foramen ovale (PFO) closure is a therapeutic option to prevent recurrent cerebral ischaemia in patients with cryptogenic stroke and transient cerebral ischaemia (TIA). The apparent lack of benefit seen in previous randomised trials has, in part, reflected inclusion of patients with alternate mechanisms of stroke. The role of formal neurology involvement in accurately delineating the likely aetiology of stroke or TIA is crucial in appropriate identification of patients for device closure.
Source: Heart, Lung and Circulation - August 4, 2016 Category: Cardiology Authors: Allan Davies, Avedis Ekmejian, Nicholas J Collins, Rohan Bhagwandeen Source Type: research

Low Dose Combination Antihypertensive Pharmacotherapy Can Be Very Effective. Angiotensin Receptor Blockers/Angiotensin Converting Enzyme Inhibitors Are Often Unnecessary
Introduction: Hypertension treatment often fails to achieve good blood pressure (BP) control, despite a wide range of available pharmacotherapy, partly because of poor side effect issues, which are often dose-related. Angiotensin receptor blockers, ARBs and angiotensin converting enzyme inhibitors, ACE-Is are known to increase BP variability, which may predispose to falls and stroke, compared to diuretics and calcium channel blockers (CCBs), which reduce BP variability.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: S. Dimmitt, A. Moran, M. Scartozzi, H. Stampfer Tags: 36 Source Type: research

New Onset Atrial Fibrillation Is Associated with Elevated Galactic-3 Levels
Background: Atrial fibrillation (AF) is associated with increased risk of stroke and cardiac mortality. Atrial remodelling and fibrosis have been suggested to participate in the pathogenesis of AF. Galectin-3 is a secreted protein that has regulatory roles in inflammation, fibrosis and tissue repair. Clinical studies have reported increased circulating galectin 3 levels and cardiac remodelling. Galectin-3 levels have been shown to predict atrial remodelling and incidence of AF. In the current investigation, we tested the hypothesis that Galectin-3 release occurs selectively in the acute phase of AF.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: D. Chen, N. Procter, V. Goh, S. Liu, S. Chua, B. Assadi-Khansari, J. Horowitz, A. Sverdlov, D. Ngo Tags: 187 Source Type: research

Successful Hybrid Coronary Artery Revascularisation in a Patient with Severe Cerebrovascular Disease - a New Treatment Option to Minimise the Risk of Stroke
Coronary artery bypass surgery (CABG) is the treatment of choice for patients with severe unprotected left main disease. CABG does however expose patients to a higher risk of cerebrovascular accidents when compared to percutaneous coronary intervention (PCI).
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: A. Challa, E. Shaw, C. Raffel, P. Pohlner Tags: 147 Source Type: research

New-Onset Complete Left Bundle Branch Block in a Patient with Heat Stroke
We present the first case of new-onset complete left bundle branch block (LBBB), which resolved with cooling and rehydration.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: D. Nayyar, M. Shatwell, A. Gandhi Tags: 118 Source Type: research

High Atrial Ectopic Activity in Stroke: An Independent Risk Factor?
Background: High atrial ectopic burden has been associated with an increased risk of developing atrial fibrillation (AF) and more recently, an increased risk of ischaemic stroke beyond manifest AF.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: A. Koshy, J. Sajeev, K. Rajakariar, P. Andrew, M. Zureik, E. Quine, S. Parfrey, M. Street, P. Venkataraman, L. Roberts, A. Teh Tags: 302 Source Type: research

Emergency Department vs Cardiac Outpatient Guideline Adherence of Anticoagulation in AF Patients
Appropriate oral anticoagulation (OAC) is an important treatment modality for atrial fibrillation (AF), to reduce risk of thromboembolic complications. However, patients presenting to the emergency department (ED) with AF often do not have their stroke risk assessed & appropriate anticoagulation instituted. The aim of this study was to compare adherence to current OAC guidelines in the ER to a specialised cardiac outpatient clinic in AF patients.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: G. Rangnekar, C. Gallagher, G. Wong, S. Rocheleau, M. Middledorp, R. Mahajan, P. Sanders, D. Lau Tags: 301 Source Type: research

Current Prescribing Trends for Atrial Fibrillation Anticoagulation in Australia
Introduction: Management of stroke risk in atrial fibrillation has changed over the last few years with the introduction of novel oral anticoagulants (NOACs) such as Apixaban, Rivaroxaban and Dabigatran. These agents are being increasingly prescribed secondary to the ease of use compared to warfarin which requires regular and ongoing INR monitoring.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: D. Pol, V. Mutha, L. Bittinger Tags: 297 Source Type: research

Left Atrial Appendage Closure in Patients with Contra-Indications to Anticoagulants
This study sought to evaluate the utility of LAA device occlusion alone without OAC in patients at high risk of stroke but at serious risk of bleeding.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: S. Kumar, V. Paul, R. Mahajan, J. Marangou, P. Waddy, D. Lau, H. Haqqani, P. Sanders Tags: 351 Source Type: research

A Case Report of Severe Myocardial Stunning and Death Following Electro-Cardioversion (ECV) for Atrial Flutter
Electro-cardioversion (ECV) is considered a safe and effective therapy to terminate atrial arrhythmias. A 72-year-old previously well man with a history of hypertension and stroke with no residual deficits, presented with 1-day history of palpitations. ECG showed incomplete RBBB, atrial flutter with rapid ventricular rate and no ischaemic changes. There was no acute reversible precipitant identified and cardiac enzymes were normal. Initial transthoracic echocardiogram (TTE) showed normal biventricular size and function, satisfactory valvular function and moderate LA dilatation.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: P. Venkataraman, A. Koshy, A. Teh, B. Chou Tags: 322 Source Type: research

Trends in Prescription of Novel Oral Anticoagulants (NOACs) and Warfarin in Australia 2010-2015
This study examines the rates of prescription of rivaroxaban, apixaban, dabigatran and warfarin over the period of July 2010 to June 2015.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: A. Vlachadis Castles, I. Tsay, W. van Gaal Tags: 321 Source Type: research

Stroke in Patients Undergoing Coronary Angiography and Percutaneous Coronary Intervention: Insights From the CADOSA Registry
The objective of this study was to assess the prevalence of periprocedural stroke in contemporary Australian practice.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: L. Halliday, R. Tavella, M. Arstall, D. Chew, M. Worthley, C. Zeitz, J. Beltrame Tags: 464 Source Type: research

10-year Australian Trends in Periprocedural Complications after PCI
We examined the incidence and predictors of bleeding, acute kidney injury (AKI) and stroke following PCI, and their impact on 30-day outcomes.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: S. Biswas, N. Andrianopoulos, A. Brennan, A. Ajani, J. Lefkovits, R. Warren, S. Duffy, D. Clark, G. New, C. Hiew, C. Reid, D. Eccleston Tags: 379 Source Type: research

Incidence of Thromboembolism and Haemorrhagic Stroke in Patients With Acute Pulmonary Embolism and Atrial Fibrillation: A Population-Linkage Study
Background: Recent studies suggest patients with acute pulmonary embolism (PE) and atrial fibrillation (AF) have increased all-cause mortality compared to patients without AF. However, the morbidity burden remains unknown.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: D. Adikari, J. Lau, V. Chow, L. Kritharides, A. Ng Tags: 634 Source Type: research

Changing Treatment Patterns in Atrial Fibrillation in Australia: Results From the Global Anticoagulation in the Field (GARFIELD) Registry
Background: Oral anticoagulant therapy (OAC) with both non-vitamin K antagonists (NOAC) and vitamin K antagonists (VKA) reduces the risk of stroke in atrial fibrillation (AF). The extent and appropriateness to which these are used in Australia is uncertain.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: H. Gibbs, A. Kakkar Tags: 622 Source Type: research