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Source: Journal of Hypertension
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Total 283 results found since Jan 2013.
A retrospective study of arterial stiffness and subsequent clinical outcomes in cancer patients undergoing percutaneous coronary intervention
Conclusion:
Atherosclerosis is advanced and accelerated in patients with malignancy, and these patients had significantly higher rates of adverse cardiovascular events, and their risk might be stratified by ABI and baPWV.
Registration:
University Hospital Medical Information Network-CTR (http://www.umin.ac.jp/ctr/).
Identifier:
Kumamoto University Malignancy and Atherosclerosis study (UMIN000028652).
Public access information:
Opt-out materials are available at the following website: http://www.kumadai-junnai.com/home/wp-content/uploads/akusei.pdf.
Source: Journal of Hypertension - March 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Heart and vessels Source Type: research
Difference in SBP between arms is a predictor of chronic kidney disease development in the general Korean population
Conclusion:
Increased IASBPD is an independent predictor of incident CKD in the general population.
Source: Journal of Hypertension - March 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Kidney Source Type: research
Carotid intima–media thickness, but not chronic kidney disease independently associates with noncardiac arterial vascular events in South Africa
Aim:
Although chronic kidney disease (CKD) as determined from estimated glomerular filtration rate (eGFR) is recommended for risk prediction by current hypertension guidelines, the equations to derive eGFR may not perform well in black Africans. We compared whether across the adult lifespan, eGFR or CKD are as closely associated with noncardiac arterial vascular events, as carotid intima–media thickness (IMT), in Africa.
Methods:
In 1152 black South Africans [480 with noncardiac arterial events (294 with critical lower limb ischemia, 186 with stroke) of which 37% were premature] and 672 age, sex and ethnicity-matche...
Source: Journal of Hypertension - March 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Kidney Source Type: research
A hybrid 4-item Krousel-Wood Medication Adherence Scale predicts cardiovascular events in older hypertensive adults
Background
: There is a need for a brief, open access, self-report medication adherence scale that overcomes challenges of existing adherence tools, is associated with incident cardiovascular disease (CVD), and identifies low ‘implementation’ adherers to antihypertensive medications to facilitate blood pressure management.
Methods and results:
Antihypertensive medication adherence was assessed in a cohort of 1532 older hypertensive adults without prior CVD using the self-report 4-item Krousel-Wood Medication Adherence Scale (K-Wood-MAS-4), a hybrid tool developed to predict pharmacy refill and which captures four ...
Source: Journal of Hypertension - March 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research
Stroke, arterial hypertension and left ventricular mechanics
No abstract available
Source: Journal of Hypertension - February 1, 2019 Category: Cardiology Tags: EDITORIAL COMMENTARIES Source Type: research
Left ventricular myocardial dysfunction in young and middle-aged ischemic stroke patients: the Norwegian stroke in the young study
Background:
Hypertension is highly prevalent in ischemic stroke patients, but less is known about its impact on subclinical left ventricular (LV) dysfunction in such patients.
Methods:
Conventional and speckle tracking echocardiography was performed in 276 young (15–44 years) and middle-aged (45–60 years) ischemic stroke patients (mean age 50 ± 9 years, 66% men). Hypertension was defined as a history of hypertension, use of antihypertensive medications, persistently elevated blood pressure (BP) during hospitalization or elevated clinic BP (≥140/90 mmHg) and ambulatory BP (≥130/80 mmHg) at follow-up vi...
Source: Journal of Hypertension - February 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Heart Source Type: research
Change in left ventricular geometry over 10 years in the elderly and risk of incident cardiovascular disease
Objective:
Left ventricular hypertrophy (LVH) is related to a poor prognosis. We aimed to determine how left ventricular (LV) geometry changes over time, and how this relates to future cardiovascular disease.
Methods:
In the Prospective Study of the Vasculature in Uppsala Seniors study, 1016 individuals were investigated with echocardiography at age 70. This was repeated after 5 and 10 years. Incident cardiovascular disease (myocardial infarction, stroke, and heart failure, n = 163) was recorded over 10 years.
Results:
LV mass index (LVMI) and LV end-diastolic diameter (LVEDD) progressively increased over 10 ye...
Source: Journal of Hypertension - January 17, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Metformin use in type 2 diabetic patients is not associated with lower arterial stiffness: the Maastricht Study
Conclusion:
We showed that there is no significant association between current metformin use and aortic stiffness, regardless of how metformin use in itself was defined. In addition, metformin use was not associated with a lower carotid stiffness. The present results showed no beneficial effect of metformin use, dosage or duration on arterial stiffness in middle-aged patients with T2D. Alternatively, metformin may exerts its cardio-protective effects via other pathways.
Source: Journal of Hypertension - January 17, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Vessels Source Type: research
Effects of blood pressure lowering on cardiovascular events, in the context of regression to the mean: a systematic review of randomized trials
Conclusion:
Clinical practice should focus less on pretreatment BP levels, which rarely predict future untreated BP levels or rule out capacity to benefit from BP lowering in high cardiovascular risk patients. Instead, focus should be on prompt, empirical treatment to maintain lower BP for those with high BP and/or high risk.
Source: Journal of Hypertension - December 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Reviews Source Type: research
Association of general and central adiposity with blood pressure among Chinese adults: results from the China National Stroke Prevention Project
Background:
The American Heart Association concluded that waist circumference was a better predictor of blood pressure risk than BMI in Asians. However, data are inconsistent and information in Chinese, the largest global population group, is limited.
Methods:
Data was obtained from the Chinese National Stroke Prevention Project Survey of a nationally representative sample of middle-aged and older Chinese adults. A total of 135 825 individuals not taking any antihypertensive drugs were included in this study. Multiple linear regression analyses were conducted to examine the association between blood pressure and par...
Source: Journal of Hypertension - November 2, 2018 Category: Cardiology Tags: ORIGINAL PAPERS Source Type: research
Impaired cardiorespiratory coupling in young normotensives with a family history of hypertension
Conclusion:
Healthy offspring of hypertensive parents have lower CRPS at rest, indicating an early impairment of cardiorespiratory coupling. Furthermore, CRPS decreased under mental stress in participants without a family history of hypertension, whereas this reactivity of CRPS was absent in participants with a family history of hypertension.
Source: Journal of Hypertension - October 4, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Hypertension of the youth Source Type: research
European Society of Hypertension position paper on renal denervation 2018
This ESH update was deemed necessary with the publication of new results of sham-controlled randomized blinded prospective trials with renal denervation (RDN). Proof of concept studies and first randomized trials (some were sham-controlled) displayed discrepant results about the efficacy of RDN. Three sham-controlled randomized trials of the 2.0 generation yielded now similarity in the average blood pressure decrease following RDN. Reduction of ambulatory blood pressure was approximately 5 to 7 mmHg and of office blood pressure 10 mmHg. Such a decrease in blood pressure by pharmacologic therapy has been found to be associa...
Source: Journal of Hypertension - September 21, 2018 Category: Cardiology Tags: Esh Statement Source Type: research
BMI is associated with the development of chronic kidney diseases in hypertensive patients with normal renal function
Objective:
We aimed to investigate the relationship of BMI and waist circumference with the development of chronic kidney disease (CKD).
Methods:
A total of 12 672 hypertensive patients with estimated glomerular filtration rate (eGFR) at least 60 ml/min per 1.73 m2 from the renal sub-study of the China Stroke Primary Prevention Trial (CSPPT) were included. The primary outcome was the development of CKD, defined as a decrease in eGFR of at least 30% and to a level of less than 60 ml/min per 1.73 m2 at the exit visit, or end-stage renal disease. A secondary outcome was rapid renal function decline, defined as ...
Source: Journal of Hypertension - September 21, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Obesity Source Type: research
Covariables and types of abnormal left ventricular geometry in nonelderly ischemic stroke survivors: the Norwegian Stroke in the Young Study
Background:
Abnormal left ventricular (LV) geometry types, like LV hypertrophy (LVH) and concentric remodelling, are independently associated with impaired prognosis in hypertension. Little is known about the prevalence and covariables of abnormal LV geometry types in younger ischemic stroke patients.
Methods:
We used clinical and echocardiographic data from 280 patients aged 15–60 years included in the Norwegian Stroke in the Young Study. LVH was defined as LV mass index greater than 46.7 g/m2.7 in women and greater than 49.2 g/m2.7 in men. Concentric remodelling was considered present if posterior wall thickne...
Source: Journal of Hypertension - September 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research
Four ECG left ventricular hypertrophy criteria and the risk of cardiovascular events and mortality in patients with vascular disease
Conclusion:
All four ECG-LVH criteria are associated with an increased risk of cardiovascular events. As Cornell/strain index is both highly prevalent and carries a high cardiovascular risk, this is likely the most relevant ECG-LVH criterion for clinical practice.
Source: Journal of Hypertension - September 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research
