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Source: Journal of Hypertension
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Total 283 results found since Jan 2013.
Low blood pressure and adverse outcomes in acute stroke: HeadPoST study explanations
Objective:
As uncertainties exist over underlying causes, we aimed to define the characteristics and prognostic significance of low blood pressure (BP) early after the onset of acute stroke.
Methods:
Post hoc analyzes of the international Head Positioning in acute Stroke Trial (HeadPoST), a pragmatic cluster-crossover randomized trial of lying flat versus sitting up in stroke patients from nine countries during 2015–2016. Associations of baseline BP and death or dependency [modified Rankin scale (mRS) scores 3–6] and serious adverse events (SAEs) at 90 days were assessed in generalized linear mixed models wi...
Source: Journal of Hypertension - January 7, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research
Comparative effects of intensive-blood pressure versus standard-blood pressure-lowering treatment in patients with severe ischemic stroke in the ENCHANTED trial
Conclusion:
Intensive BP lowering is associated with increased mortality in patients with severe AIS despite lowering the risk of ICH. Further randomized trials are required to provide reliable evidence over the optimum SBP target in the most serious type of AIS.
Trial registration:
ClinicalTrials.gov Identifier: NCT01422616.
Source: Journal of Hypertension - January 7, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research
Office, central and ambulatory blood pressure for predicting incident atrial fibrillation in older adults
Conclusion:
In a predominantly older, stroke-free community-based cohort, ABP was a better independent predictor of incident atrial fibrillation than central BP, whereas office BP was inadequate for this purpose.
Source: Journal of Hypertension - December 11, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure and other risk factors Source Type: research
Combined effect of high depressive symptom burden and hypertension on new-onset stroke: evidence from a nationwide prospective cohort study
Conclusion:
Our results suggest a combined effect of high depressive symptom burden and hypertension on stroke risk among the middle-aged and elderly Chinese.
Source: Journal of Hypertension - December 11, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure and other risk factors Source Type: research
Effects of vascular compression on the rostral ventrolateral medulla for blood pressure variability in stroke patients
Conclusion:
Although RVLM compression was closely associated with BP variability in the subacute ischemic stroke phase, an effect of RVLM compression on stroke outcome was not observed.
Source: Journal of Hypertension - November 6, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Risk factors Source Type: research
Influence of cardiovascular risk factors on arterial hypertension and mild cognitive impairment in 4602 participants of the ELITE study
Background:
In ELITE (Ernährung, Lebensstil und individuelle Information zur Verhinderung von Herzinfarkt, Schlaganfall und Demenz; german for: Nutrition, Lifestyle and Individual Information for the Prevention of Heart Attack, Stroke and Dementia) data on cardiovascular risk factors, cognitive function and quality of life are prospectively collected, which will be improved through targeted individual information. The aim is to improve the health of the participants and identify the reasons for the lack of implementation.
Methods:
Risk factors of 4602 participants were linked to (controlled) hypertension and mi...
Source: Journal of Hypertension - November 6, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Cognitive function Source Type: research
Creatinine increase following initiation of antihypertensives is associated with cardiovascular risk: a nationwide cohort study
Conclusion:
In primary care, patients initiating first-line antihypertensive treatment, an increase in plasma creatinine above 30% was associated with increased absolute 6-month risk of cardiovascular event.
Source: Journal of Hypertension - November 6, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment aspects Source Type: research
Epidemiological characteristics and related factors of frailty in older Chinese adults with hypertension: a population-based study
Conclusion:
The current study provides the first evidence regarding the status of frailty in older Chinese adults with hypertension.
Source: Journal of Hypertension - October 9, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology and risk factors Source Type: research
New progress on the study of aortic stiffness in age-related hypertension
Hypertension is a worldwide known cause of morbidity and mortality in the elderly and is a major risk factor for cardiovascular complications such as stroke, myocardial infarction, renal complications and heart failure. Although the mechanisms of hypertension remain largely unknown, a recent new concept is that aortic stiffening is a cause of hypertension in middle-aged and older individuals, which highlighted the importance of aortic stiffening in the development of age-related hypertension. Understanding the pathogenesis of aortic stiffness therefore became one of the important approaches to preventing and controlling hy...
Source: Journal of Hypertension - September 5, 2020 Category: Cardiology Tags: REVIEWS AND META-ANALYSES Source Type: research
Positive relationship of hypertensive retinopathy with carotid intima--media thickness in hypertensive patients
Objectives:
We aimed to explore the relationship of hypertensive retinopathy with carotid intima--media thickness (CIMT), and to examine the possible effect modifiers in Chinese adults with hypertension.
Methods:
We conducted a cross-sectional study of 12 342 hypertensive patients with complete exit site visit data from the China Stroke Primary Prevention Trial. CIMT was measured by carotid ultrasonography. Hypertensive retinopathy was diagnosed according to the Keith--Wagener--Barker classification.
Results:
The mean (SD) CIMT among study participants was 739.9 (111.4) μm. Compared with patients with grade 1 hy...
Source: Journal of Hypertension - September 5, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Vessels, heart, brain & kidney Source Type: research
What is the optimal blood pressure level for patients with atrial fibrillation treated with direct oral anticoagulants?
Conclusion:
SBP values below 161 mmHg are associated higher all-cause mortality, but lower event risk in patients with atrial fibrillation on DOAC therapy. The nadir SBP for lowest event rate was 120 mmHg, for lowest cardiovascular mortality was 130 mmHg and for lowest all-cause mortality was 160 mmHg. This demonstrates a need for a prospective interventional study of BP control after initiation of anticoagulation.
Source: Journal of Hypertension - August 13, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research
Effects of dapagliflozin and gliclazide on the cardiorenal axis in people with type 2 diabetes
Conclusion:
Dapagliflozin seemingly influences systemic and renal hemodynamics independently and beyond glucose lowering in people with type 2 diabetes.
This clinical trial was registered at https://clinicalTrials.gov (ID: NCT02682563).
Source: Journal of Hypertension - August 13, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research
Ambulatory blood pressure variability and risk of cardiovascular events, all-cause mortality, and progression of kidney disease
Conclusion:
Greater ambulatory SBP variabilities were associated with increased risks for nonfatal cardiovascular diseases, all-cause mortality, and rapid kidney function decline in patients with CKD.
Source: Journal of Hypertension - August 13, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: BP variability Source Type: research
Blood pressure variability at midlife is associated with all-cause, coronary heart disease and stroke long term mortality
Conclusion:
In this cohort of tenured male workers, BPV taken over 5 years was clearly associated with 18-year all-cause, CHD and stroke mortality.
Source: Journal of Hypertension - August 13, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: BP variability Source Type: research
Beta-blockers in hypertension: overview and meta-analysis of randomized outcome trials
Conclusion:
Compared with other antihypertensive agents, beta-blockers appear to be substantially less protective against stroke and overall mortality. However, they exhibit a substantial risk-reducing ability for all events when prescribed to lower BP in patients with modest or more clear BP elevations, and therefore can be used as additional agents in hypertensive patients.
Source: Journal of Hypertension - August 13, 2020 Category: Cardiology Tags: REVIEWS AND META-ANALYSES Source Type: research
