Filtered By:
Source: Journal of Hypertension
This page shows you your search results in order of date. This is page number 7.
Order by Relevance | Date
Total 283 results found since Jan 2013.
Prevalence of refractory hypertension in the United States from 1999 to 2014
Conclusions:
We provided the first nationally representative estimate of refractory hypertension prevalence in US adults.
Source: Journal of Hypertension - August 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Achievement of target SBP without attention to decrease in DBP can increase cardiovascular morbidity in treated arterial hypertension: the Campania Salute Network
Objectives:
Results of the SPRINT study have influenced recent guidelines on arterial hypertension, in the identification of target SBP, but scarce attention has been paid to the consequences on DBP. However, there is evidence that reducing DBP too much can be harmful.
Methods:
We analyzed outcome in 4005 treated hypertensive patients (22% obesity, 8% diabetes and 21% current smoking habit) with target attended office SBP less than 140 mmHg, in relation to quintiles of DBP, cardiovascular risk profile and target organ damage (LV hypertrophy, carotid plaque and left atrial dilatation). Composite fatal and nonfatal ca...
Source: Journal of Hypertension - August 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research
Long-term clinical outcomes according to the mean observed blood pressure in patients with coronary artery disease after drug-eluting stent implantation
Background:
A recent guideline emphasized strict blood pressure (BP) control for the patients at high risk for cardiovascular events. However, there are little data about the relationship between BP control and clinical outcome in Korea. We sought to evaluate the clinical outcomes according to the mean observed BP in patients with coronary artery disease (CAD) who had undergone drug-eluting stent (DES) implantation.
Methods:
We reviewed records of 1010 CAD patients with DES from 2010 through 2011. After excluding in-hospital mortality cases (n = 79), we categorized patients into two groups based on the average SBP...
Source: Journal of Hypertension - August 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research
Does the benefit from treating to lower blood pressure targets vary with age? A systematic review and meta-analysis
Conclusion:
In these novel results, for both RR and absolute risk, treating to SBPs of 120–140 mmHg versus higher targets benefited older patients more than younger patients without an age-related increase in the RR for adverse effects. Nonetheless, because all clinical trials excluded the most frail older patients, clinicians must consider individual patient characteristics such as frailty, autonomy, and cognitive ability when choosing blood pressure targets.
Source: Journal of Hypertension - June 27, 2019 Category: Cardiology Tags: REVIEWS AND META-ANALYSES Source Type: research
Leisure-time cross-country skiing is associated with lower incidence of hypertension: a prospective cohort study
Conclusion:
Total volume as well as duration of leisure time cross-country skiing are each continuously, inversely, and independently associated with future risk of hypertension in a white male population.
Source: Journal of Hypertension - June 27, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
A new approach to identifying hypertension-associated genes in the mesenteric artery of spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats
Conclusion:
The overexpression of Kcnq1, Crlf1, Alb and Xirp1 and the inhibition of Galr2, Kcnh1, Ache, Chrm2 and Slc5a7 expression may indicate that a relationship exists between these genes and the cause and/or worsening of hypertension in SHR and SHRSP.
Source: Journal of Hypertension - June 27, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Experimental hypertension Source Type: research
Incremental prognostic value of global left atrial peak strain in women with new-onset gestational hypertension
Background:
Left atrial strain and strain rate parameters, measured by bidimensional-speckle tracking echocardiography, have been proposed as predictors of atrial fibrillation, stroke, congestive heart failure and cardiovascular death. However, they have not yet been tested in hypertensive disorders of pregnancy. The aim of this study was to assess the prognostic role of global left atrial peak strain (GLAPS) in a population of pregnant women with new-onset hypertension in a medium-term follow-up.
Methods:
Twenty-seven consecutive women with new-onset hypertension after 20 weeks pregnancy and 23 age-matched, race-matc...
Source: Journal of Hypertension - June 27, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research
Blood pressure levels and risk of cardiovascular disease mortality among Japanese men and women: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study)
Conclusion:
BP categories at baseline were linearly and positively associated with CVD mortality overall and also among participants not taking antihypertensive medication. A higher risk of mortality from CVD was observed among patients already treated for hypertension with optimal and normal BPs than those with high-normal BP, suggesting the importance of careful monitoring of BP and comorbidities of such patients.
Source: Journal of Hypertension - May 30, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Moderate morning rise in blood pressure has lowest risk of stroke but only in women
Background:
The morning period which is recognized as the highest risk for cardiovascular events is associated with a surge in blood pressure (BP). However, it is unclear what aspect of this rise is important.
Aim:
To determine whether the rate of rise (RoR), the magnitude (day night difference) or the product [BP power (BPPower)] is associated with increased cardiovascular risk.
Methods:
We developed a logistic equation method to fit individual 24-h patterns of BP to determine RoR, amplitude and BPPower using the ambulatory recordings from the Ohasama study including 564 men and 971 women (16.6 years follow-up).
...
Source: Journal of Hypertension - May 30, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: BP variability Source Type: research
Effects of vasodilating medications on cerebral haemodynamics in health and disease: systematic review and meta-analysis
Objectives:
Vasodilating antihypertensives prevent stroke and potentially cerebral small vessel disease but their effects on cerebrovascular haemodynamics beyond blood pressure lowering are unclear.
Methods:
We searched PubMed, Medline, Embase, Cinahl, Psychinfo, Health Business Elite and Health Management Information Consortium for randomized studies of vasodilating medications, compared to no treatment or nonvasodilators, that reported effects on cerebral blood flow (CBF), mean blood flow velocity (MFV) or cerebrovascular reactivity. Absolute and standardized mean differences (SMD) were combined by inverse-variance ...
Source: Journal of Hypertension - April 27, 2019 Category: Cardiology Tags: REVIEWS Source Type: research
Impact of early initiation of antihypertensive medications for patients with hypertension or elevated blood pressure
Conclusion:
Initiating antihypertensive medications before experiencing a cardiovascular disease-related clinical event was associated with reduced risk of AMI, stroke and death for all hypertensive patients identified in the new guidelines. However, early treatment had a significantly smaller effect for patients with only ‘elevated’ BP, who experienced just a lower risk of stroke once treated.
Source: Journal of Hypertension - April 27, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research
Recurrent vertigo is a predictor of stroke in a large cohort of hypertensive patients
Conclusion:
Hypertensive patients with dizziness did not have a high-risk profile at baseline, but those with vertigo must be carefully followed over years because of the higher stroke mortality.
Source: Journal of Hypertension - March 29, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Transgenic overexpression of glutathione S-transferase μ-type 1 reduces hypertension and oxidative stress in the stroke-prone spontaneously hypertensive rat
Background:
Combined congenic breeding and microarray gene expression profiling previously identified glutathione S-transferase μ-type 1 (Gstm1) as a positional and functional candidate gene for blood pressure (BP) regulation in the stroke-prone spontaneously hypertensive (SHRSP) rat. Renal Gstm1 expression in SHRSP rats is significantly reduced when compared with normotensive Wistar Kyoto (WKY) rats. As Gstm1 plays an important role in the secondary defence against oxidative stress, significantly lower expression levels may be functionally relevant in the development of hypertension. The aim of this study was to invest...
Source: Journal of Hypertension - March 29, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage/mechanistic aspects Source Type: research
SBP and antihypertensive treatment in the acute phase after stroke and its impact on the risk of falling
The objectives of this study were to describe SBP development among patients in the acute phase after stroke, and to investigate whether intensified antihypertensive treatment during this phase was associated with short-term prognosis regarding the risk of falling.
Patients and methods:
This observational study is a sub-study of the Fall Study of Gothenburg and included 421 consecutive patients admitted to a stroke unit. Medical records were studied for blood pressure measurements, antihypertensive treatment and falls. Random coefficient models for repeated measures data was used to study change in SBP. Univariable Cox ...
Source: Journal of Hypertension - March 29, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research
Neurocognition in treatment-resistant hypertension: profile and associations with cardiovascular biomarkers
Conclusion:
Neurocognitive impairments are common in adults with treatment-resistant hypertension, particularly on tests of executive function. Better neurocognition is independently associated with aerobic fitness, microvascular function, and CVRFs.
Source: Journal of Hypertension - March 29, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research
