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Source: Journal of Hypertension
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Total 283 results found since Jan 2013.
Estimated carotid–femoral pulse wave velocity has similar predictive value as measured carotid–femoral pulse wave velocity
Conclusion: ePWV predicted major cardiovascular events independently of SCORE, FRS and cfPWV indicating that these traditional risk scores have underestimated the complicated impact of age and blood pressure on arterial stiffness and cardiovascular risk.
Source: Journal of Hypertension - June 4, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Brunei epidemiological stroke study: patterns of hypertension and stroke risk
Conclusion: The prevalence of hypertension in Brunei is high in both women and men. Information campaigns and prevention programs are needed to be able to cope with the increasing problem of hypertension and resulting diseases like stroke in Brunei in the near future.
Source: Journal of Hypertension - June 4, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research
Impact of hypertension on mortality and cardiovascular disease burden in patients with cardiovascular risk factors from a general practice setting: the ESCARVAL-risk study
Conclusion: Our results highlight the relevance of hypertension as main risk factor for mortality and cardiovascular events in a real-life setting. Although our data support the ongoing need of cardiovascular risk factors prevention, intensified actions for primary prevention of hypertension show potential to largely reduce the burden of cardiovascular disease.
Source: Journal of Hypertension - April 29, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Aortic root dimension and arterial stiffness in arterial hypertension: the Campania Salute Network
Objectives: The relation between aortic root dimension (ARD) and measures of arterial stiffness is uncertain. Accordingly, we studied the relation between ARD and an estimate of arterial stiffness in 12 392 hypertensive patients (age 53 ± 12 years, 43% women) free of prevalent cardiovascular disease and with ejection fraction at least 50%, from the Campania Salute Network Registry.
Methods: Echocardiographic ARD was measured and compared with the value predicted by age, sex and height by using a z-score. Arterial stiffness was assessed by the pulse pressure/stroke index. The highest population tertile of pulse pres...
Source: Journal of Hypertension - April 29, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Blood vessels Source Type: research
Prognostic value of longitudinal strain of subepicardial myocardium in patients with hypertension
Conclusion: EpiLS was the only independent prognostic factor in regularly-treated hypertensive patients. Our results indicated that involvement of subepicardial myocardium may infer worse prognosis of hypertensive heart disease.
Source: Journal of Hypertension - April 29, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Heart Source Type: research
Comprehensive monitoring of cardiac remodeling with aortic stroke volume values provided by a phase-contrast MRI sequence
Conclusion: The determination of aortic SV with a phase-contrast sequence leads to a significant enhancement in the characterization and monitoring of cardiac remodeling.
Source: Journal of Hypertension - April 1, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Heart Source Type: research
White-coat hypertension and cardiovascular events: a meta-analysis
Conclusion: The cardiovascular morbidity and mortality associated with WCH may be slightly higher compared with normotension but well below the risks associated with sustained HTN.
Source: Journal of Hypertension - March 4, 2016 Category: Cardiology Tags: Reviews Source Type: research
Effects of blood pressure lowering on outcome incidence in hypertension: 7. Effects of more vs. less intensive blood pressure lowering and different achieved blood pressure levels – updated overview and meta-analyses of randomized trials
Conclusion: Updating of previous meta-analyses indicates that more vs. less intense BP lowering can reduce not only stroke and coronary events, but also cardiovascular mortality. Including data from recent RCTs also shows that all major outcomes can be reduced by lowering SBP a few mmHg below vs. above 130 mmHg, but absolute risk reduction becomes smaller, suggesting patients at lower initial SBP were at a lower level of cardiovascular risk.
Source: Journal of Hypertension - March 4, 2016 Category: Cardiology Tags: Reviews Source Type: research
Angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers and the risk of major adverse cardiac events in patients with diabetes and prior stroke: a nationwide study
Conclusion: Our study supports the hypothesis that the risks of MACEs and two additional secondary outcomes in patients with diabetes who survived ischemic stroke did not differ according to ACEI versus ARB use.
Source: Journal of Hypertension - January 30, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research
Increased myocardial vulnerability to ischemia–reperfusion injury in the presence of left ventricular hypertrophy
Objective: Despite its high prevalence among patients suffering myocardial infarction, the significance of left ventricle hypertrophy for infarct size is not known. We asked whether infarct size might be increased by this condition, and whether any such increase might be associated with an increased mitochondrial damage following coronary occlusion.
Methods: Occlusion of the left descending artery in isolated, perfused hearts of SHR-SP (spontaneously hypertensive rat stroke-prone) (left ventricular hypertrophy) or Wistar-Kyoto (WKY) (control) rats was used, followed by reperfusion with or without exendin-4 (Exe-4), a gluc...
Source: Journal of Hypertension - January 30, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Heart Source Type: research
Effects of blood pressure-lowering treatment. 6. Prevention of heart failure and new-onset heart failure – meta-analyses of randomized trials
Conclusion: BP-lowering treatment effectively prevents ’new onset’ heart failure. It is suggested that BP lowering by calcium antagonists is effective as BP lowering by other drugs in preventing ‘new-onset’ heart failure, unless the trial design creates an unbalance against calcium antagonists.
Source: Journal of Hypertension - January 30, 2016 Category: Cardiology Tags: Reviews Source Type: research
Continuation of the ESH-CHL-SHOT trial after publication of the SPRINT: rationale for further study on blood pressure targets of antihypertensive treatment after stroke
No abstract available
Source: Journal of Hypertension - January 30, 2016 Category: Cardiology Tags: Editorial Source Type: research
A stop-codon of the phosphodiesterase 11A gene is associated with elevated blood pressure and measures of obesity
Objective: To identify stop-codon variants associated with blood pressure (BP).
Methods: Illumina exome chip was genotyped in 5453 individuals of the population-based Malmö Diet and Cancer Study. We compared BP levels between carriers and noncarriers of all stop-codon variants found in at least 10 individuals and characterized these further based on literature evidence of functionality. Next, the association to ischemic stroke was evaluated in 2278 cases of ischemic stroke and 5969 controls.
Results: We identified 19 stop-codon variants with nominally significant BP associations (P
Source: Journal of Hypertension - January 30, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Genetic aspects Source Type: research
Silent brain infarcts in high blood pressure patients with cardiac implantable electronic devices: unmasking silent atrial fibrillation
Background: Hypertensive patients present a higher risk for developing atrial fibrillation and its complications. Cardiac implantable electronic devices (CIEDs) have shown reliable atrial fibrillation detection as atrial high-rate episodes (AHREs). The presence of AHRE more than 5 min has been related to increased risk of stroke, but a high proportion of ischemic brain lesions (IBLs) could be subclinical and thromboembolic risk underestimated.
Methods: We included hypertensive patients with CIED and we analyzed the incidence of AHRE and the presence of IBL on computed tomography (CT) scan.
Results: One hundred and twenty...
Source: Journal of Hypertension - December 23, 2015 Category: Cardiology Tags: ORIGINAL PAPERS: Heart Source Type: research
Trends in admission blood pressure and stroke outcome in patients with acute stroke and transient ischemic attack in a National Acute Stroke registry
Objective: Elevated blood pressure (BP) is common during an acute stroke and is associated with unfavorable outcome. Management of hypertension has improved in recent years. We aimed to evaluate trends in admission BP levels in patients admitted with acute stroke and transient ischemic attack (TIA) over the past decade.
Methods: Data were based on the National Acute Stroke Israeli Registry. The study population comprised 6177 patients, aged at least18 years admitted for acute stroke (4382 ischemic stroke and 476 intracerebral hemorrhage) or TIA (1227) and had data on BP levels on admission. We studied temporal trends in ad...
Source: Journal of Hypertension - December 23, 2015 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research
