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Source: Journal of Hypertension
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Total 283 results found since Jan 2013.
One year of isometric exercise training for blood pressure management in men: a prospective randomized controlled study
Objective:
Isometric exercise training (IET) over 4–12 weeks is an effective antihypertensive intervention. However, blood pressure (BP) reductions are reversible if exercise is not maintained. No work to date has investigated the long-term effects of IET on resting BP.
Methods:
We randomized 24 unmedicated patients with high-normal BP to a 1-year wall squat IET intervention or nonintervention control group. Resting BP and various clinically important haemodynamic variables, including heart rate (HR), stroke volume (SV), cardiac output (CO) and total peripheral resistance (TPR) were measured pre and post the...
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Prediction of long-term outcomes by arterial stiffness and pressure wave reflections in patients with acute stroke: the Athens Stroke Registry
Background and purpose:
Stroke patients’ management might be improved by addressing the role of aortic stiffness (carotid-femoral pulse wave velocity: cfPWV) and pressure wave reflections (PWRs, augmentation index: AIx) in their pathogenesis and outcome. We tested the hypothesis that cfPWV and AIx, separately and combined, predict long-term outcomes [all-cause mortality, incidence of cardiovascular events, stroke recurrence and disability defined by modified Ranking Scale (mRS) ≥3] in patients with acute stroke, using data from the ‘Athens Stroke Registry’.
Methods:
Data from 552 patients (70% men, age: ...
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Forkhead box O3 longevity genotype may attenuate the impact of hypertension on risk of intracerebral haemorrhage
Conclusions:
The longevity-associated FOXO3
G allele may attenuate the impact of hypertension on ICH risk.
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Predictive power of 24-h ambulatory pulse pressure and its components for mortality and cardiovascular outcomes in 11 848 participants recruited from 13 populations
Conclusion:
This study provides a new basis for associating PP components with outcome and arterial properties in different age groups and at different pulse rates for both old and young age. The similarity between adjusted and unadjusted hazard ratios supports the clinical usefulness of PP components but further studies are needed to assess the prognostic significance of the PP components, especially at the young age.
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Hypertension, remnant cholesterol and cardiovascular disease: evidence from the China health and retirement longitudinal study
Conclusion:
Our study indicated that there was a combined effect of hypertension and RC on the risk of CVD, stroke and cardiac events. Larger-sample prospective cohort studies are still required to test the potential application of combination of hypertension and RC as a screening method to identify individuals at risk of CVD.
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Changes in blood pressure and cardiovascular disease in middle-aged to older Chinese: the Guangzhou Biobank Cohort Study
Conclusion:
Most people between 50 and 70 years of age and not taking antihypertensive medication maintained a slow increase SBP trajectory over a follow-up period of approximately 7 years. However, those whose SBPs increased from low and moderate levels were associated with higher CVD risks.
Source: Journal of Hypertension - September 5, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Mineralocorticoid receptor antagonism improves transient receptor potential vanilloid 4-dependent dilation of cerebral parenchymal arterioles and cognition in a genetic model of hypertension
Conclusions:
These data advance our understanding of the effects of hypertension on cerebral arterioles using a clinically relevant model and treatment paradigm. Our studies suggest TRPV4 and the MR are potential therapeutic targets to improve cerebrovascular function and cognition during hypertension.
Source: Journal of Hypertension - August 13, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Silent brain infarcts, peripheral vascular disease and the risk of cardiovascular events in patients with hypertension
Conclusion:
Assessment of SBI and ABI less than 0.9 may refine the cardiovascular risk stratification in patients with hypertension.
Source: Journal of Hypertension - July 30, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Prevalence and associated factors of obstructive sleep apnea in refractory hypertension
Conclusion:
In this large RHT cohort, resistant and refractory hypertensive patients have similar OSA prevalence, although refractory ones, which by definition use spironolactone, are younger and apparently have a better sleep pattern.
Source: Journal of Hypertension - July 1, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Lifestyle modification and cognitive function among individuals with resistant hypertension: cognitive outcomes from the TRIUMPH trial
Background:
Resistant hypertension is associated with increased risk of cognitive decline, stroke, and dementia. Lifestyle modification has been suggested to improve cognitive function through its salutary effects on vascular function.
Methods:
Participants included 140 patients with resistant hypertension participating in the TRIUMPH trial. Participants were randomized to a cardiac rehabilitation-based lifestyle program (C-LIFE) or a standardized education and physician advice condition (SEPA). Participants completed a 45-min cognitive test battery consisting of tests of Executive Functioning and Learning, Memo...
Source: Journal of Hypertension - July 1, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Impact of estimated pulse wave velocity and socioeconomic status on the risk of stroke in men: a prospective cohort study
Objective:
High pulse wave velocity (PWV) and low socioeconomic status (SES) are each associated with increased risk of stroke, but clarification of the interplay between PWV, SES and the risk of stroke appears to be warranted to identify vulnerable populations at high risk of stroke. We conducted a prospective study that examined the independent and joint associations of PWV and SES with the risk of stroke in the general population.
Methods:
The current study included 2666 men aged 42–61 years, who were enrolled in the Kuopio Ischaemic Heart Disease Study cohort. Estimated PWV (ePWV), a proxy of carotid-fem...
Source: Journal of Hypertension - May 26, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Nebivolol and incident cardiovascular events in hypertensive patients compared with nonvasodilatory beta blockers
Conclusion:
The vasodilatory beta blocker nebivolol was associated with reduced incident cardiovascular events compared with nonvasodilatory beta blockers. Additional study of other beta blockers is necessary to determine if this is a vasodilatory beta blocker class effect or is specific to nebivolol.
Graphical abstract:
http://links.lww.com/HJH/B916
Source: Journal of Hypertension - May 1, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Association between DBP and major adverse cardiovascular events in patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention
Background:
In patients with stable coronary artery disease, low DBP is associated with an increased risk of myocardial infarction and cardiovascular death, but its association with clinical outcomes in patients with acute myocardial infarction undergoing percutaneous coronary intervention (PCI) is unknown.
Methods:
Consecutive patients with ST-segment elevation myocardial infarction (STEMI) undergoing PCI from January 2010 to June 2016 were enrolled. The patients were divided into five groups according to the quintiles of DBP at admission. The primary outcome was in-hospital major adverse cardiovascular events ...
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Retinal microvascular abnormalities and risks of incident stroke and its subtypes: The Circulatory Risk in Communities Study
Conclusion:
Retinal microvascular abnormalities were positively associated with the risk of incident stroke in the general Japanese population. Routine retinal photography could provide positive clinical insights into stroke risk stratification independent of blood pressure, antihypertensive medication use, and other risk factors.
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Blood pressure undulation of peripheral thrombolysis period in acute ischemic stroke is associated with prognosis
Conclusion:
Higher BPV and SBP from prior IVT to 72 h after IVT was associated with higher risk of stroke outcomes within 3 months.
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
