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Source: Journal of Hypertension
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Total 283 results found since Jan 2013.
Fenofibrate attenuates cardiac and renal alterations in young salt-loaded spontaneously hypertensive stroke-prone rats through mitochondrial protection
Conclusion:
The results suggest that the cardiorenal protective effects of fenofibrate in young male salt-loaded SHRSPs are explained by its capacity to preserve mitochondrial function.
Source: Journal of Hypertension - March 27, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Pathophysiological aspects Source Type: research
Effect of total, domain-specific, and intensity-specific physical activity on all-cause and cardiovascular mortality among hypertensive adults in China
Objectives:
We aimed to prospectively examine the associations of total, domain-specific, and intensity-specific physical activity with all-cause and cardiovascular mortality among Chinese hypertensive adults.
Methods:
We performed a prospective cohort study in 150 391 hypertensive participants aged 30–79 years from the China Kadoorie Biobank study of 512 891 participants recruited from 10 diverse areas across China during 2004–2008. Participants with heart disease, stroke, chronic obstructive pulmonary disease, and cancer at baseline were excluded.
Results:
During 1069 863 person-years of follow-up (medi...
Source: Journal of Hypertension - March 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Lifestyle Source Type: research
Gender, blood pressure, and cardiovascular and renal outcomes in adults with hypertension from the Systolic Blood Pressure Intervention Trial
Conclusion:
In adults with hypertension but not with diabetes, treatment to a systolic blood pressure goal of less than 120 mmHg, compared with a goal of less than 140 mmHg, resulted in no heterogeneity of effect between men and women on cardiovascular or renal outcomes, or on rates of serious adverse events.
ClinicalTrials.gov number, NCT01206062.
Source: Journal of Hypertension - March 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research
Brachial–ankle pulse wave velocity compared with mean arterial pressure and pulse pressure in risk stratification in a Chinese population
Conclusion:
With fatal and nonfatal cardiovascular and cerebrovascular endpoints as outcome, baPWV marginally increases risk stratification over and beyond MAP, but is a better predictor than PP. A threshold of 16.7 m/s might be used in Chinese populations.
Source: Journal of Hypertension - February 2, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Blood vessels Source Type: research
The predictive role of CHA2DS2–VASc score between venous thromboembolism and ischemic stroke: a large-scale cohort study
Conclusion:
Our study is the first to concern the performance of CHA2DS2–VASc score in predicting the risk of ischemic stroke in VTE patients and the risk of VTE in ischemic stroke patients. Nevertheless, the performance of the score was modest, and the transportability of the score in these populations still needs to be defined.
Source: Journal of Hypertension - February 2, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research
Cardiovascular risk and blood pressure lowering treatment among elderly individuals: Evidence for Cardiovascular Prevention from Observational Cohorts in Japan
Conclusion:
Although impact on BP was more evident among young-old than old-old individuals, clinicians who prescribe antihypertensive medication to elderly patients should consider that such patients require further monitoring.
Source: Journal of Hypertension - January 17, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research
Early life exposure to Chinese famine modifies the association between hypertension and cardiovascular disease
Objective:
Studies have shown that famine exposure during early life may increase the risk of cardiovascular disease (CVD), hypertension, and diabetes during adulthood. We aimed to assess whether exposure to the Chinese famine (1959–1961) modifies the association between hypertension and CVD.
Methods:
We investigated data of 5772 adults born between 1954 and 1964 from the China Health and Retirement Longitudinal Study. CVD was based on self-reported doctor's diagnosis of heart problems (heart attack, coronary heart disease, angina, congestive heart failure, or other heart problems) and stroke.
Results:
Overall, h...
Source: Journal of Hypertension - November 30, 2017 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Risk of stroke and coronary heart disease among various levels of blood pressure in diabetic and nondiabetic Chinese patients
Conclusion:
HTN was associated with a two-fold increased risk of CHD and a three-fold increased risk of stroke compared with normotension irrespective of diabetes status. For diabetic patients with HTN, a more comprehensive method is essential for assessing cardiovascular risk.
Source: Journal of Hypertension - November 30, 2017 Category: Cardiology Tags: ORIGINAL PAPERS: Diabetes Source Type: research
Apparent resistant hypertension and the risk of vascular events and mortality in patients with manifest vascular disease
Conclusion:
In hypertensive patients with clinically manifest vascular disease, presence of controlled and uncontrolled aRH is related to an increased risk of cardiovascular mortality and all-cause mortality.
Source: Journal of Hypertension - November 30, 2017 Category: Cardiology Tags: ORIGINAL PAPERS: Resistant hypertension Source Type: research
Home blood pressure predicts stroke incidence among older adults with impaired physical function: the Ohasama study
Conclusion: Higher home BP was associated with increased risk of stroke even among those with impaired physical function. Measurements of home BP would be useful for stroke prevention, even after physical function decline.
Source: Journal of Hypertension - November 2, 2017 Category: Cardiology Tags: ORIGINAL PAPERS: BP measurement Source Type: research
Diurnal variation and repeatability of arterial stiffness and cardiac output measurements in the third trimester of uncomplicated pregnancy
Aim: To investigate same day repeated measures and diurnal variation of arterial stiffness, cardiac output (CO), stroke volume (SV) and total peripheral resistance (TPR) during the third trimester of normal pregnancy.
Methodology: Pulse wave velocity (PWV) and augmentation index (AIx) were recorded using the Arteriograph, while CO, SV and TPR were recorded using noninvasive cardiac output monitoring. The measurements were obtained in the third trimester of pregnancy from 21 healthy pregnant women at four time points (morning, afternoon, evening and midnight) over a 24-h period. Triplicate measurements of 67 women were obt...
Source: Journal of Hypertension - November 2, 2017 Category: Cardiology Tags: ORIGINAL PAPERS: Blood vessels Source Type: research
Effects of blood-pressure-lowering treatment on outcome incidence. 12. Effects in individuals with high-normal and normal blood pressure: overview and meta-analyses of randomized trials
Conclusion: Individuals with very high cardiovascular risk due to symptomatic cardiovascular disease should consider BP-lowering treatment even when their BP is in the high-normal and normal range.
Source: Journal of Hypertension - September 28, 2017 Category: Cardiology Tags: Reviews Source Type: research
Normal cerebral vascular pulsations in humans: changes with age and implications for microvascular disease
Background: Cerebral syndromes in older humans, secondary stroke in younger persons following trauma, and sickle cell anaemia in children, are linked by unexplained microvascular damage and high cerebral pressure or flow pulsations. The aim of this study was to characterize age-related pressure and flow waveforms patterns entering the brain, to explain these in terms of disturbed physiological function, and to consider clinical implications.
Method: Blood flow velocity waves were measured in four cerebral vascular territories by transcranial Doppler of 1020 apparently normal patients (497 men, 21–78 years). Central pres...
Source: Journal of Hypertension - September 28, 2017 Category: Cardiology Tags: ORIGINAL PAPERS: Blood vessels Source Type: research
A differential expression of uncoupling protein-2 associates with renal damage in stroke-resistant spontaneously hypertensive rat/stroke-prone spontaneously hypertensive rat-derived stroke congenic lines
Conclusion: A differential UCP2 expression associates with different degree of renal damage upon Japanese diet in two SHRSR/SHRSP-derived stroke congenic lines through modulation of mitochondrial function, inflammation, and oxidative stress.
Source: Journal of Hypertension - August 3, 2017 Category: Cardiology Tags: ORIGINAL PAPERS: Kidney Source Type: research
