Metformin use in type 2 diabetic patients is not associated with lower arterial stiffness: the Maastricht Study

Conclusion: We showed that there is no significant association between current metformin use and aortic stiffness, regardless of how metformin use in itself was defined. In addition, metformin use was not associated with a lower carotid stiffness. The present results showed no beneficial effect of metformin use, dosage or duration on arterial stiffness in middle-aged patients with T2D. Alternatively, metformin may exerts its cardio-protective effects via other pathways.
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Vessels Source Type: research