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Remote Lower White Matter Integrity Increases the Risk of Long-Term Cognitive Impairment After Ischemic Stroke in Young Adults Clinical Sciences
Conclusions— These findings indicate that although stroke has an acute onset, it might have long lasting effects on remote white matter integrity and thereby increases the risk of long-term cognitive impairment.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Schaapsmeerders, P., Tuladhar, A. M., Arntz, R. M., Franssen, S., Maaijwee, N. A. M., Rutten-Jacobs, L. C. A., Schoonderwaldt, H. C., Dorresteijn, L. D. A., van Dijk, E. J., Kessels, R. P. C., de Leeuw, F.-E. Tags: Magnetic Resonance Imaging (MRI), Cognitive Impairment, Ischemic Stroke Clinical Sciences Source Type: research

Brain Imaging and Cognitive Predictors of Stroke and Alzheimer Disease in the Framingham Heart Study Clinical Sciences
Conclusions— Specific patterns of cognitive and brain structural measures observed even in early aging predict stroke risk and may serve as biomarkers for risk prediction.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Weinstein, G., Beiser, A. S., DeCarli, C., Au, R., Wolf, P. A., Seshadri, S. Tags: Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Shape of the Central Sulcus and Disability After Subcortical Stroke: A Motor Reserve Hypothesis Clinical Sciences
Conclusions— The severity of disability in patients with a positive history of small subcortical ischemic stroke caused by a severe cerebral small vessel disease is related to the shape of the central sulcus, independently of the main determinants of disability. These results support the concept of a motor reserve that could modulate the clinical severity in patients with a positive history of small subcortical ischemic stroke.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Jouvent, E., Sun, Z. Y., De Guio, F., Duchesnay, E., Duering, M., Ropele, S., Dichgans, M., Mangin, J.-F., Chabriat, H. Tags: Magnetic Resonance Imaging (MRI), CADASIL, Ischemic Stroke Clinical Sciences Source Type: research

Functional Trajectories, Cognition, and Subclinical Cerebrovascular Disease Clinical Sciences
Conclusions—PI-SBI moderated the association between cognition and functional trajectories, with 3-fold greater decline among those with PI-SBI (compared with no PI-SBI) and normal baseline cognition. This highlights the strong and independent association between subclinical markers and patient-centered trajectories over time.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Mandip S. Dhamoon, Ying-Kuen Cheung, Jose Gutierrez, Yeseon P. Moon, Ralph L. Sacco, Mitchell S.V. Elkind, Clinton B. Wright Tags: Epidemiology, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Anxiety in Patients With Acute Ischemic Stroke: Risk Factors and Effects on Functional Status
Conclusion: Depressive symptoms are the major correlates of PSA while more severe PSA is associated with poorer ADL and health-related QOL. Acute lesions involving CHWM may correlate with PSA in ischemic stroke patients with mild-to-moderate neurologic deficits, supporting a lesion-location hypothesis in PSA.IntroductionAnxiety is prevalent after stroke and occurs in about one-quarter of stroke survivors (1, 2). Poststroke anxiety (PSA) may have a negative impact on quality of life (QOL) of stroke survivors, affecting their rehabilitation (3). Furthermore, one prospective study found that severe anxiety symptoms were assoc...
Source: Frontiers in Psychiatry - April 16, 2019 Category: Psychiatry Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Frequency of Hemorrhage on Follow Up Imaging in Stroke Patients Treated With rt-PA Depending on Clinical Course
Conclusions: Frequency of hemorrhagic transformation in Routine follow-up brain imaging and consecutive changes in therapeutic management were different depending on clinical course measured by NHISS score. Introduction Brain imaging 24–36 h after systemic thrombolysis for acute ischemic stroke is recommended in American Stroke Association and European Stroke Organization guidelines (1, 2). Brain imaging is performed to detect secondary bleeding or hemorrhagic transformation in order to adapt medical stroke prevention if necessary. Guideline recommendations are based on the results of the first study on rt-PA...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

A Genetic Variant of miR-34a Contributes to Susceptibility of Ischemic Stroke Among Chinese Population
This study was supported by National Natural Science Foundation of China (Nos. 81560552, 81260234), Natural Science Foundation of Guangxi Zhuang Autonomous Region (CN) (2017JJA180826), Innovation Project of Guangxi Graduate Education (CN) (201601009) and Key Laboratory Open Project Fund of Guangxi Zhuang Autonomous Region (CN) (kfkt20160064). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supplementary Material The Supplementary Material for this article can be fou...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

What Are the Classifications of Perinatal Stroke?
Discussion Perinatal stroke occurs in about 1:1000 live births and is a “focal vascular injury from the fetal period to 28 days postnatal age.” Perinatal stroke is the most common cause of hemiparetic cerebral palsy and causes other significant morbidity including cognitive deficits, learning disabilities, motor problems, sensory problems including visual and hearing disorders, epilepsy, and behavioral and psychological problems. Family members are also affected because of the potential anxiety and guilt feelings that having a child with a stroke presents, along with the care that may be needed over the child&#...
Source: PediatricEducation.org - May 1, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Lesion-aphasia discordance in acute stroke among Bengali-speaking patients: Frequency, pattern, and effect on aphasia recovery
ConclusionLesion-aphasia discordance following acute stroke is not uncommon among Bengali-speaking subjects. In the discordant group, preponderance towards non-fluent aphasia was observed. Discordance occurred more frequently after hemorrhagic stroke. Subjects with lesion-discordant aphasia presented better recovery during early post-stroke phase.
Source: Journal of Neurolinguistics - July 29, 2019 Category: Speech-Language Pathology Source Type: research

Neurodevelopmental outcome after neonatal perforator stroke
AimTo assess outcome after neonatal perforator stroke in the largest cohort to date. MethodSurvivors from a cohort of children diagnosed with neonatal perforator stroke using cranial ultrasound or magnetic resonance imaging were eligible for inclusion. Recovery and Recurrence Questionnaire score, presence of cerebral palsy (CP), and crude outcome were assessed, specifically (1) the ability to walk independently, (2) participation in regular education, and (3) the presence of epilepsy. ResultsThirty‐seven patients (20 males, 17 females) aged 3 to 14 years (mean age 8y) were included in the study: 14 with isolated single ...
Source: Developmental Medicine and Child Neurology - July 27, 2015 Category: Child Development Authors: Ginette M Ecury‐Goossen, Marit Haer, Liesbeth S Smit, Monique Feijen‐Roon, Maarten Lequin, Rogier C J Jonge, Paul Govaert, Jeroen Dudink Tags: Original Article Source Type: research

Disrupted brain functional network topology in unilateral acute brainstem ischemic stroke
This study aimed to investigate the topological properties of brain functional connectome in unilateral acute brainstem ischemic stroke using graph theory. Fifty-three acute brainstem ischemic stroke patients, consisted of 27 left-sided and 26 right-sided brainstem stroke patients, and 20 age, gender, and education-matched healthy controls (HCs) were recruited to undergo a resting-state functional magnetic resonance imaging (rs-fMRI) scan in this study. Graph theory analyses were then used to examine the group-specific topological properties of the functional connectomes seperately. The unilateral acute brainstem stroke pa...
Source: Brain Imaging and Behavior - July 22, 2020 Category: Neurology Source Type: research

Neuroanatomical correlates of macrostructural receptive abilities in narrative discourse in unilateral left hemisphere stroke: A behavioural and voxel-based morphometry study
CONCLUSIONS & IMPLICATIONS: The present results suggest that retelling and comprehension of auditory and written narratives are relatively well-preserved in individuals with a LH stroke without significant aphasia, but poorer than in HC. The findings replicate previous studies conducted in groups with higher levels of education and SES both at the behavioural and neural levels. Considering that naming seems to be associated with narrative retell and comprehension in individuals with lower SES and education, this research provides evidence on the importance of pursuing further studies including larger samples with and witho...
Source: International Journal of Language and Communication Disorders - November 30, 2022 Category: Speech-Language Pathology Authors: Sabrine Amaral Martins Townsend Karine Marcotte Amelie Brisebois Anderson Dick Smidarle Fernanda Schneider Fernanda Loureiro Ricardo Bernardi Soder Alexandre da Rosa Franco Luiz Carlos Porcello Marrone Lilian Cristine H übner Source Type: research

Nationwide Patterns of Magnetic Resonance Imaging Utilization among Stroke and Transient Ischemic Attack Patients in the Emergency Department (P2.309)
CONCLUSIONS: Nationwide patterns of MRI utilization among ischemic stroke and TIA patients demonstrate variations given an urban vs. rural setting and the patient’s triage status. These results characterize factors associated with MRI use in the ED and may guide efforts in better understanding MRI use in EDs among ischemic stroke and TIA patients on a nationwide basis.Disclosure: Dr. Ng has nothing to disclose. Dr. Fu has nothing to disclose. Dr. He has nothing to disclose. Dr. Cen has nothing to disclose. Dr. Mack has nothing to disclose. Dr. Liebeskind has received personal compensation for activities with Stryker ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ng, A., Fu, K., He, S., Cen, S., Mack, W., Liebeskind, D., Sanossian, N. Tags: Cerebrovascular Disease and Interventional Neurology: Education and TIA Source Type: research

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