Gait parameters in children with bilateral spastic cerebral palsy: a systematic review of randomized controlled trials
AimTo identify the gait parameters used to assess gait disorders in children with bilateral spastic cerebral palsy (CP) and evaluate their responsiveness to treatments.MethodA systematic search within PubMed, Web of Science, and Scopus (in English, 2000 –2016) for randomized controlled trials of children with bilateral spastic CP who were assessed by instrumented gait analysis (IGA) was performed. Data related to participants and study characteristics, risk of bias, and outcome measures were collected. A list of gait parameters responsive to clin ical interventions was obtained.ResultsTwenty ‐one articles met the i...
Source: Developmental Medicine and Child Neurology - November 28, 2018 Category: Child Development Authors: Cristina G ómez‐Pérez, Josep M Font‐Llagunes, Joan Carles Martori, Joan Vidal Samsó Tags: Systematic Review Source Type: research

Administrative databases to monitor the prevalence of cerebral palsy
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 27, 2018 Category: Child Development Authors: Elodie Sellier Tags: Commentary Source Type: research

Motor function in Rett syndrome: comparing clinical and parental assessments
AimTo describe a new clinical tool, the Rett Syndrome Motor Evaluation Scale (RESMES) and to assess (loco ‐)motor function in people with Rett syndrome (RTT).MethodFormal assessment provided by physicians was followed by parents ’ direct observation at home using the RESMES. Sixty females (mean [SD] age 12y 5mo [8y 9mo], range 3–40y) with a clinical diagnosis and genetically determined RTT participated in the study. Spearman's/Pearson's coefficients assessed the correlation between the clinicians’ and caregivers’ ev aluations, as well as the correlation of RESMES scores with other scales, namely t...
Source: Developmental Medicine and Child Neurology - November 26, 2018 Category: Child Development Authors: Marina L Rodocanachi Roidi, Ioannis U Isaias, Francesca Cozzi, Francesca Grange, Fabrizia M Scotti, Valentina F Gestra, Alessandra Gandini, Enrico Ripamonti Tags: Original Article Source Type: research

Prefrontal and temporal cortical thickness in adolescents with traumatic brain injury
AimTo investigate the impact of traumatic injury on the developing prefrontal ‐temporal adolescent cortex, and correlated brain structural measures with neurocognitive functioning.MethodNineteen adolescents (12 males, 7 females, age range: 11 –17y, mean 15y 8mo, standard deviation 1y 7mo, median 15y 11mo) with traumatic brain injury (TBI) were included. Cortical thickness of frontal and temporal lobes was assessed using magnetic resonance imaging. We correlated cortical thickness of prefrontal‐temporal regions with age, time since in jury, and neurocognitive functioning, and compared these results with a matched ...
Source: Developmental Medicine and Child Neurology - November 25, 2018 Category: Child Development Authors: Catharine Vander Linden, Helena Verhelst, Gregory Verleysen, Karen Caeyenberghs, Karel Deblaere, Guy Vingerhoets Tags: Original Article Source Type: research

Hamstring lengthening in cerebral palsy and the use of musculoskeletal modelling
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 25, 2018 Category: Child Development Authors: Caroline Stewart Tags: Commentary Source Type: research

The crisis in replicability
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 25, 2018 Category: Child Development Authors: Alan S Rigby, Steven M Day Tags: Commentary Source Type: research

Mycophenolate mofetil in the treatment of pediatric autoimmune central nervous system disease
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 25, 2018 Category: Child Development Authors: Cory Stingl, Heather Van Mater Tags: Commentary Source Type: research

Long ‐term muscle changes after hamstring lengthening in children with bilateral cerebral palsy
AimTo evaluate short ‐term (1y postoperatively; E1) and long‐term (at least 4y postoperatively; E2) changes in hamstring muscle‐tendon length (MTL) and lengthening velocity after hamstring lengthening in children with bilateral cerebral palsy (CP).MethodThree ‐dimensional gait analysis was performed in 19 children (16 males, 3 females; 36 limbs; mean age at surgery 9y [SD 3y]; range 6–10y) with flexed knee gait, preoperative ankle dorsiflexion lower than 20 degrees, and CP before bilateral hamstring lengthening (E0), at E1 and E2. Hamstring MTL (norm alized by leg length) and velocity were assessed via OpenSi...
Source: Developmental Medicine and Child Neurology - November 25, 2018 Category: Child Development Authors: Firooz Salami, Julia Brosa, Stefan Van Drongelen, Matthias C M Klotz, Thomas Dreher, Sebastian I Wolf, Mirjam Thielen Tags: Original Article Source Type: research

Transcranial direct current stimulation in children with autism spectrum disorder: a systematic scoping review
AimOur aim was to review available studies which test transcranial direct current stimulation (tDCS) to reduce symptom severity in children with autism spectrum disorder (ASD).MethodWe performed a systematic scoping review in PubMed and PsychINFO databases for studies employing tDCS in children and adolescents with ASD.ResultsWe found five studies (two small randomized controlled studies, one experimental study, one quasi ‐experimental study, and one case study) reporting positive effects of tDCS in ASD symptom reduction. Study design varied greatly and sample size ranged from 1 to 20 patients.InterpretationPreliminary e...
Source: Developmental Medicine and Child Neurology - November 19, 2018 Category: Child Development Authors: Ana Alexandra Caldas Os ório, Andre Russowsky Brunoni Tags: Invited Review Source Type: research

How socio ‐economic disadvantage modifies health outcomes in children with cerebral palsy
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 16, 2018 Category: Child Development Authors: Maryam Oskoui, Carmen Messerlian Tags: Commentary Source Type: research

Missed outpatient appointments and unplanned healthcare: the real question is ‘why’?
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 16, 2018 Category: Child Development Authors: Jane V Appleton Tags: Commentary Source Type: research

Home ‐based early intervention in infants and young children with visual impairment using the Developmental Journal: longitudinal cohort study
AimTo investigate the effects of home ‐based early intervention in children with severe visual impairment using the Developmental Journal for babies and young children with visual impairment (DJVI).MethodA longitudinal observational study was undertaken with a national cohort (OPTIMUM) of infants with congenital disorders of the peripheral visual system (CDPVS) and profound ‐severe visual impairment; and followed up after 12 months and 24 months. Intervention was categorized according to the practitioner diary records of their usual practice over 12 months from baseline comparing those receiving the DJVI...
Source: Developmental Medicine and Child Neurology - November 13, 2018 Category: Child Development Authors: Naomi J Dale, Elena Sakkalou, Michelle A O'Reilly, Clare Springall, Hanna Sakki, Sarah Glew, Eleni Pissaridou, Michelle De Haan, Alison T Salt Tags: Original Article Source Type: research

Acute flaccid myelitis: an emerging clinical entity
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 12, 2018 Category: Child Development Authors: Akihisa Okumura, Harushi Mori Tags: Commentary Source Type: research

Outcome of paediatric acute flaccid myelitis associated with enterovirus D68: a case series
We report five cases of AFM in previously typically developing children (2–6y) from South East Scotland during September and October 2016 after infection with EV‐D68 (all detected in the nasopharyngeal aspirates). All cases pr esented with significant neurological symptoms, which were severe in two cases requiring intensive care support because of respiratory paralysis. At 18‐month follow‐up, two cases remain ventilator‐dependent with other cases requiring ongoing community rehabilitation. These cases represent one of the largest reported paediatric cluster of AFM associated with EV‐D68 in Europe. The epide...
Source: Developmental Medicine and Child Neurology - November 12, 2018 Category: Child Development Authors: Amir Kirolos, Kate Mark, Jay Shetty, Nandita Chinchankar, Catherine Mcdougall, Paul Eunson, Janet Stevenson, Kate Templeton, NHS Lothian EV ‐D68 Associated AFM Study Group Tags: Case Series Source Type: research

Autophagy in childhood neurological disorders
Autophagy is a tightly modulated lysosomal degradation pathway. Genetic disorders of autophagy during nervous system development may lead to developmental delay, neurodegeneration, and other neurological signs in children. Here we aimed to summarize single gene disorders that perturb various steps of autophagy pathway and their roles in the causation of childhood neurological diseases. Numerous childhood ‐onset disorders are caused by mutations that impact the autophagy pathway. These can manifest with a range of features including ataxia, spastic paraplegia, and intellectual disability. Defective proteins causing such d...
Source: Developmental Medicine and Child Neurology - November 12, 2018 Category: Child Development Authors: Ye Zhu, Gautam Runwal, Pawel Obrocki, David C Rubinsztein Tags: Invited Review Source Type: research

Decreasing prevalence of cerebral palsy in birth cohorts in South Carolina using Medicaid, disability service, and hospital discharge data, 1996 to 2009
AimSince cross ‐sectional trends of 8‐year‐old cerebral palsy (CP) birth prevalence based on record review were stable from 1985 to 2002 in Metropolitan Atlanta, we examined birth cohort trends using administrative data sets promptly.MethodAmong 755  433 live births from 1996 to 2009 in South Carolina, 2080 received CP diagnosis by age 4 years from linked Medicaid claims with International Classification of Diseases, Ninth Revision codes 343.X (contributing 1061 [51%] unique cases), hospital discharge data (57 [3%] unique cases), and Departmen t of Disabilities and Special Needs program (64 [3%] unique cases). T...
Source: Developmental Medicine and Child Neurology - November 12, 2018 Category: Child Development Authors: Qing Li, Stephen L Kinsman, Dorothea D Jenkins, Melbourne F Hovell, Rita M Ryan Tags: Original Article Source Type: research

Feeding and swallowing impairment in children with stroke and unilateral cerebral palsy: a systematic review
AimThis systematic review targeted frequency estimates of dysphagia (feeding and swallowing problems), related health outcomes, and caregiver burden in children with stroke or unilateral cerebral palsy (CP).MethodSix electronic databases were searched from their inception to November 2017 along with a manual search of eight relevant journals. Two blinded raters assessed abstracts and full articles for eligibility. Discrepancies were resolved by consensus. Accepted articles were evaluated for quality. Data were extracted and analysed descriptively.ResultsOf 1660 abstracts, five met inclusion criteria, of which three focused...
Source: Developmental Medicine and Child Neurology - November 9, 2018 Category: Child Development Authors: Victoria Sherman, Elissa Greco, Mahendranath Moharir, Deryk Beal, Kevin Thorpe, Rosemary Martino Tags: Systematic Review Source Type: research

Development of hand function during the first year of life in children with unilateral cerebral palsy
AimTo identify developmental trajectories of hand function in infants aged 3 months to 12 months with unilateral cerebral palsy (CP).MethodInfants at high risk of unilateral CP were recruited from 3 months of age from follow ‐up programmes and clinics in Sweden, the Netherlands, Italy, and Australia. Measurements on the Hand Assessment for Infants (HAI) were completed until 12 months of age. Group‐based trajectory modelling was used to identify subgroups of infants with similar trajectories of development. Multinomi al logistic regression determined associations between demographic variables and trajectory membership.R...
Source: Developmental Medicine and Child Neurology - November 8, 2018 Category: Child Development Authors: Leanne Sakzewski, Elisa Sicola, Cornelia H Verhage, Giuseppina Sgandurra, Ann ‐Christin Eliasson Tags: Original Article Source Type: research

Efficacy of cannabinoids in paediatric epilepsy
There are hundreds of compounds found in the marijuana plant, each contributing differently to the antiepileptic and psychiatric effects. Cannabidiol (CBD) has the most evidence of antiepileptic efficacy and does not have the psychoactive effects of ∆9‐tetrahydrocannabinol. CBD does not act via cannabinoid receptors and its antiepileptic mechanism of action is unknown. Despite considerable community interest in the use of CBD for paediatric epilepsy, there has been little evidence for its use apart from anecdotal reports, until the last year. T hree randomized, placebo‐controlled, double‐blind trials in Dravet synd...
Source: Developmental Medicine and Child Neurology - November 6, 2018 Category: Child Development Authors: Shayma Ali, Ingrid E Scheffer, Lynette G Sadleir Tags: Invited Review Source Type: research

The validity of early intervention for children with visual impairment
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 5, 2018 Category: Child Development Authors: Belinda Deramore Denver Source Type: research

Quantitative gait analysis: assessment of interobserver reliability
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 5, 2018 Category: Child Development Authors: Jon Davids Source Type: research

Epidemiology of cerebral palsy in Bangladesh: a population ‐based surveillance study
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 5, 2018 Category: Child Development Authors: Gulam Khandaker, Mohammad Muhit, Tasneem Karim, Hayley Smithers ‐Sheedy, Iona Novak, Cheryl Jones, Nadia Badawi Source Type: research

Table of Contents
Developmental Medicine&Child Neurology,Volume 60, Issue 12, Page 1187-1189, December 2018. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 5, 2018 Category: Child Development Source Type: research

Acknowledgement of translators, 2018
Developmental Medicine&Child Neurology,Volume 60, Issue 12, Page 1294-1294, December 2018. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 5, 2018 Category: Child Development Source Type: research

Acknowledgement of referees, 2018
Developmental Medicine&Child Neurology,Volume 60, Issue 12, Page 1291-1293, December 2018. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 5, 2018 Category: Child Development Source Type: research

Childhood disability and how we see the world
Developmental Medicine&Child Neurology,Volume 60, Issue 12, Page 1190-1190, December 2018. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 5, 2018 Category: Child Development Authors: Peter Rosenbaum Source Type: research

DMCN 2018 highlights: 60 years on …
Developmental Medicine&Child Neurology,Volume 60, Issue 12, Page 1191-1191, December 2018. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 5, 2018 Category: Child Development Authors: Bernard Dan Source Type: research

Spontaneous infant movements that predict later cerebral palsy: reply to Hadders ‐Algra and Philippi
Developmental Medicine&Child Neurology,Volume 60, Issue 12, Page 1289-1289, December 2018. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 5, 2018 Category: Child Development Authors: Amanda K L Kwong, Joy E Olsen, Tara L FitzGerald, Lex W Doyle, Jeanie L Y Cheong, Alicia J Spittle Source Type: research

Overlapping samples in systematic reviews and meta ‐analyses: interpreting findings of cognitive outcomes following preterm birth
Developmental Medicine&Child Neurology,Volume 60, Issue 12, Page 1290-1290, December 2018. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - November 5, 2018 Category: Child Development Authors: Dido Green Source Type: research

Management of pain in children and adolescents with cerebral palsy: a systematic review
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 31, 2018 Category: Child Development Authors: Katarina Ostojic, Simon P Paget, Angela M Morrow Source Type: research

The need for long ‐term multidisciplinary attention after stroke
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 31, 2018 Category: Child Development Authors: Stijn Roggeman, Chris Truyers Source Type: research

Best use of the tuberous sclerosis complex ‐associated neuropsychiatric disorders (TAND) checklist
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 31, 2018 Category: Child Development Authors: Petrus J De Vries, Anna Jansen Source Type: research

Outpatient appointment non ‐attendance and unplanned health care for children and young people with neurological conditions: a retrospective cohort study
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 29, 2018 Category: Child Development Authors: Stuart Jarvis, John Livingston, Anne ‐Marie Childs, Lorna Fraser Source Type: research

Cognitive, adaptive, and behavioral profiles and management of alternating hemiplegia of childhood
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 26, 2018 Category: Child Development Authors: Joan M Jasien, Melanie Bonner, Richard D'alli, Lyndsey Prange, Melissa Mclean, Monisha Sachdev, Julie Uchitel, Jennifer Ricano, Brian Smith, Mohamad A Mikati Source Type: research

The Standardized Infant NeuroDevelopmental Assessment: validation of a new scale
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 26, 2018 Category: Child Development Authors: Sally Jary Source Type: research

Mental health disorders and physical risk factors in children with cerebral palsy: a cross ‐sectional study
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 26, 2018 Category: Child Development Authors: Daniel G Whitney, Seth A Warschausky, Mark D Peterson Source Type: research

Longitudinal trajectories and reference centiles for the impact of health conditions on daily activities of children with cerebral palsy
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 24, 2018 Category: Child Development Authors: Doreen J Bartlett, Jan Willem Gorter, Lynn M Jeffries, Lisa Avery, Steven E Hanna, On Track Study Team, Westcott McCoy, Lisa Chiarello, Robert Palisano, Alyssa Fiss, Barb Galuppi, Monica Smersh, Lisa Diller, Paula Drew, Nancy Ford, Marquith Source Type: research

Dance and rehabilitation in cerebral palsy: a systematic search and review
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 23, 2018 Category: Child Development Authors: Citlali L ópez‐Ortiz, Deborah J Gaebler‐Spira, Sara N Mckeeman, Reika N Mcnish, Dido Green Source Type: research

Cerebral palsy and maternal obesity
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 23, 2018 Category: Child Development Authors: Cara D Dolin Source Type: research

Developmental trajectory of self ‐care in children with cerebral palsy with different manual abilities
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 22, 2018 Category: Child Development Authors: Chia ‐Ling Chen Source Type: research

Improving the future for families with disabled children
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 22, 2018 Category: Child Development Authors: Riccardo Ribera Source Type: research

Effect of ankle foot orthoses on motor performance in cerebral palsy
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 22, 2018 Category: Child Development Authors: Marc Degelaen Source Type: research

Measuring change in gait performance of children with motor disorders: assessing the Functional Mobility Scale and the Gillette Functional Assessment Questionnaire walking scale
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 20, 2018 Category: Child Development Authors: Corinne Ammann ‐Reiffer, Caroline H G Bastiaenen, Hubertus J A Van Hedel Source Type: research

Reversible cerebral vasoconstriction syndrome: a rare arteriopathy of childhood
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 20, 2018 Category: Child Development Authors: Nomazulu Dlamini Source Type: research

Cerebellar malformations in children: determining long ‐term neurological outcomes
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 15, 2018 Category: Child Development Authors: Michael S Salman, Mario Manto Source Type: research

Developmental outcomes in children with congenital cerebellar malformations
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 15, 2018 Category: Child Development Authors: Elana F Pinchefsky, Andrea Accogli, Michael I Shevell, Christine Saint ‐Martin, Myriam Srour Source Type: research

Medial gastrocnemius volume and echo ‐intensity after botulinum neurotoxin A interventions in children with spastic cerebral palsy
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 15, 2018 Category: Child Development Authors: Simon ‐Henri Schless, Francesco Cenni, Lynn Bar‐On, Britta Hanssen, Barbara Kalkman, Thomas O'brien, Erwin Aertbeliën, Anja Van Campenhout, Guy Molenaers, Kaat Desloovere Source Type: research

Respiratory morbidity in children with cerebral palsy: an overview
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 15, 2018 Category: Child Development Authors: Lieve Boel, Kurt Pernet, Michel Toussaint, Kris Ides, Glenn Leemans, Jurn Haan, Kim Van Hoorenbeeck, Stijn Verhulst Source Type: research

Parent report on quality of life in post ‐haemorrhagic hydrocephalus
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 15, 2018 Category: Child Development Authors: Andrew Whitelaw Source Type: research

Interobserver reliability in the interpretation of three ‐dimensional gait analysis in children with gait disorders
Developmental Medicine&Child Neurology, EarlyView. (Source: Developmental Medicine and Child Neurology)
Source: Developmental Medicine and Child Neurology - October 15, 2018 Category: Child Development Authors: Kemble K Wang, Jean L Stout, Andrew J Ries, Tom F Novacheck Source Type: research