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Drug: Proton Pump Inhibitors PPIs

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Total 238 results found since Jan 2013.

Concomitant Use of NSAIDs or SSRIs with NOACs Requires Monitoring for Bleeding.
CONCLUSION: When NSAIDs or SSRIs are required for NOAC users with AF, physicians need to monitor bleeding events and consider the use of PPIs, especially for combined use of both drugs or when initiating NOACs treatment. PMID: 32882758 [PubMed - in process]
Source: Yonsei Medical Journal - August 31, 2020 Category: Universities & Medical Training Authors: Lee MT, Park KY, Kim MS, You SH, Kang YJ, Jung SY Tags: Yonsei Med J Source Type: research

Association of Proton Pump Inhibitors With Higher Risk of Cardiovascular Disease and Heart Failure
To examine associations of cumulative exposure to proton pump inhibitors (PPIs) with total cardiovascular disease (CVD; composed of stroke, coronary heart disease, and heart failure [HF]) and HF alone in a cohort study of White and African American participants of the Atherosclerosis Risk in Communities (ARIC) study.
Source: Mayo Clinic Proceedings - October 1, 2021 Category: Internal Medicine Authors: Elizabeth J. Bell, Suzette J. Bielinski, Jennifer L. St. Sauver, Lin Y. Chen, Mary R. Rooney, Nicholas B. Larson, Paul Y. Takahashi, Aaron R. Folsom Tags: Original article Source Type: research

A historical cohort study to investigation of statins safety in COVID-19 hospitalized patients
CONCLUSION: The use of statins did not seem to change outcomes in COVID19.PMID:34776254 | DOI:10.1016/j.therap.2021.10.006
Source: Therapie - November 15, 2021 Category: Psychiatry & Psychology Authors: Saeed Nateghi Mohammad Mahmoudi Gomari Hadiseh Hosamirudsari Behnam Behnoush Asma Razmjoofard Goli Azimi Shokooh Ordookhani Ali Jafarpour Neda Faraji Source Type: research

Omeprazole-clopidogrel interaction and neurovascular complications after flow-diverter device placement
Conclusion Omeprazole was associated with a significant increase in the mean P2Y12 reactivity level among patients with intracranial aneurysms treated with flow-diverting devices who received clopidogrel. However, receipt of omeprazole was not associated with an increased risk of ischemic events or stent stenosis. For neuroendovascular patients who are treated with a flow diverter while receiving clopidogrel, alternative gastrointestinal medication regimens should be considered.
Source: Journal of NeuroInterventional Surgery - March 18, 2022 Category: Neurosurgery Authors: Catapano, J. S., Srinivasan, V. M., Wakim, A. A., Lundberg, J. N., Rutledge, C., Cole, T. S., Baranoski, J. F., Fredrickson, V. L., Rahmani, R., Albuquerque, F. C., Ducruet, A. F. Tags: Hemorrhagic stroke Source Type: research

Acid suppressants use and risk of atherosclerotic cardiovascular disease in middle-aged and older adults
CONCLUSIONS: PPIs were associated with increased risk of ASCVD, particularly amongst participants without indications for medication. Our findings are of important practical significance and suggest that clinicians should be cautious in prophylactic use of PPIs.PMID:36113328 | DOI:10.1016/j.atherosclerosis.2022.09.001
Source: Atherosclerosis - September 16, 2022 Category: Cardiology Authors: Yue Ma Shu Li Hongxi Yang Yuan Zhang Huiping Li Lihui Zhou Jing Lin Yanchun Chen Yabing Hou Xinyu Zhang Tong Liu Xin Zhou Yaogang Wang Source Type: research

Proton pump inhibitors and the risk of cardiovascular events and cardiovascular mortality: A systematic review and meta-analysis of observational studies
CONCLUSION: It is questionable, whether PPI monotherapy constitutes a cardiovascular risk factor.PMID:36195531 | DOI:10.1016/j.ejim.2022.09.021
Source: European Journal of Internal Medicine - October 4, 2022 Category: Internal Medicine Authors: Michael Nolde Nayeon Ahn Tobias Dreischulte Evamaria Krause Florian G üntner Alexander G ünter Roman Gerlach Martin Tauscher Ute Amann Jakob Linseisen Christa Meisinger Sebastian-Edgar Baumeister Ina-Maria R ückert-Eheberg Source Type: research

Proton Pump Inhibitor and Clopidogrel Use After Percutaneous Coronary Intervention and Risk of Major Cardiovascular Events
ConclusionsIn patients who receive clopidogrel after PCI, concomitant use of PPI seems to increase the risk of major cardiovascular events.
Source: Cardiovascular Drugs and Therapy - November 11, 2022 Category: Cardiology Source Type: research

Does proton pump inhibitor reduce the antiaggregant efficacy of aspirin in ischemic stroke?
Acta Neurol Taiwan. 2023 Mar 30;32(1):9-15.NO ABSTRACTPMID:36474449
Source: Acta Neurologica Taiwanica - December 7, 2022 Category: Neurology Authors: Tu ğba Özel Ali Ünal Sebahat Özdem Babur Dora Source Type: research