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Drug: Proton Pump Inhibitors PPIs

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Total 238 results found since Jan 2013.

Antidepressants and the Risk of Ischemic Stroke in Older Adults According to the Degree of Serotonin Reuptake Inhibition: A Retrospective Cohort Study
CONCLUSION: The use of strong and intermediate SRIs should be considered carefully in older adult patients, especially when high-dose antidepressants are prescribed even for a short duration.PMID:37562992 | DOI:10.1016/j.jagp.2023.07.013
Source: Am J Geriatr Psychia... - August 10, 2023 Category: Geriatrics Authors: Kyoung-Eun Kwon Bo Ram Yang Mi-Sook Kim Byung-Joo Park Joongyub Lee Sun-Young Jung Source Type: research

Long-Term Risk of Acute Myocardial Infarction, Stroke, and Death With Outpatient Use of Clarithromycin: A Retrospective Cohort Study
AbstractIn a retrospective cohort study of patients enrolled in the UK Clinical Practice Research Datalink during 2000 –2013, we evaluated long-term risks of death, stroke, and acute myocardial infarction (AMI) in adults prescribed clarithromycin. Patients were outpatients aged 40–85 years, who were prescribed clarithromycin (n = 287,748), doxycycline (n = 267,729), or erythromycin (n = 442,999), orHelicobacter pylori eradication therapy with a proton pump inhibitor, amoxicillin, and either clarithromycin (n = 27,639) or metronidazole (n = 14,863). We analyzed time to death, stroke, or AMI with Cox proportional hazards...
Source: American Journal of Epidemiology - September 20, 2017 Category: Epidemiology Source Type: research

Association Between Proton Pump Inhibitor Use and Risk of  Stroke
We read with interest the article by Nguyen et  al1 evaluating the association between proton pump inhibitor (PPI) use and ischemic stroke. The authors found that PPI use was associated with a significant increase in the risk of ischemic stroke after adjustment for established risk factors for stroke including smoking status, body mass index, p hysical activity, dietary quality, alcohol use, menopausal hormone use in women, multivitamin use, regular aspirin use, regular nonaspirin nonsteroidal anti-inflammatory drug, use and personal history of hypertension, hyperlipidemia, coronary artery disease, or diabetes.
Source: Gastroenterology - August 6, 2018 Category: Gastroenterology Authors: Cong Dai, Min Jiang, Ming-Jun Sun Tags: Correspondence Source Type: research

Proton ‐Pump Inhibitor Use and the Risk of First‐Time Ischemic Stroke in the General Population
This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - October 28, 2017 Category: Internal Medicine Authors: Cong Dai, Min Jiang, Qin Cao Tags: Letter to the Editor Source Type: research

Does proton pump inhibitor reduce the antiaggregant efficacy of aspirin in ischemic stroke?
CONCLUSION: The combination of 30 mg lansoprazole and 100 mg aspirin does not cause a decrease in antiaggregant activity in the early period, but chronic use was not evaluated in this study. Patients with AR may benefit from an increase in the dose of aspirin.PMID:36474449
Source: Acta Neurologica Taiwanica - December 7, 2022 Category: Neurology Authors: Tu ğba Özel Ali Ünal Sebahat Özdem Babur Dora Source Type: research