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Drug: Insulin
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Total 1988 results found since Jan 2013.
Nuts and seeds consumption and risk of cardiovascular disease, type 2 diabetes and their risk factors: a systematic review and meta-analysis
CONCLUSION: There is a probable relationship between consumption of nuts/seeds and lower risk of CVD, mostly driven by CHD, possibly in part through effects on blood lipids. More research on stroke and T2D may affect the conclusions. The evidence of specific nuts should be further investigated.PMID:36816545 | PMC:PMC9930735 | DOI:10.29219/fnr.v67.8961
Source: Food and Nutrition Research - February 23, 2023 Category: Nutrition Authors: Erik Kristoffer Arnesen Birna Thorisdottir Linnea B ärebring Fredrik S öderlund Bright I Nwaru Ulrike Spielau Jutta Dierkes Alfons Ramel Christel Lamberg-Allardt Agneta Åkesson Source Type: research
Insulin-like Growth Factor 1 and Risk of Cardiovascular Disease: Results from the UK Biobank Cohort Study
CONCLUSION: This study indicates that both low and high levels of circulating IGF-1 are associated with increased risk of CVD in general population. These results highlight the importance of monitoring IGF-1 status on cardiovascular health.PMID:36810801 | DOI:10.1210/clinem/dgad105
Source: The Journal of Clinical Endocrinology and Metabolism - February 22, 2023 Category: Endocrinology Authors: Jiayang Lin Linjie Yang Junlin Huang Yating Liu Xuzhen Lei Ruxin Chen Bingyan Xu Chensihan Huang Weijuan Dou Xueyun Wei Deying Liu Peizhen Zhang Yan Huang Zhimin Ma Huijie Zhang Source Type: research
Short communication: unique metabolic signature of proliferative retinopathy in the tear fluid of diabetic patients with comorbidities — preliminary data for PPPM validation
AbstractType 2 diabetes (T2DM) defined as the adult-onset type that is primarily not insulin-dependent, comprises over 95% of all diabetes mellitus (DM) cases. According to global records, 537 million adults aged 20-79 years are affected by DM that means at least 1 out of 15 persons. This number is projected to grow by 51% by the year 2045. One of the most common complications of T2DM is diabetic retinopathy (DR) with an overall prevalence over 30%. The total number of the DR-related visual impairments is on the rise, due to the growing T2DM population. Proliferative diabetic retinopathy (PDR) is the progressing DR and lea...
Source: EPMA Journal - February 22, 2023 Category: International Medicine & Public Health Source Type: research
The impact of the metabolic score for insulin resistance on cardiovascular disease: a 10-year follow-up cohort study
ConclusionThe elevated METS-IR was independently associated with incident CVD, suggesting that the METS-IR might be a valuable indicator for risk stratification and early intervention of CVD.
Source: Journal of Endocrinological Investigation - February 17, 2023 Category: Endocrinology Source Type: research
Association between the triglyceride-glucose index and stroke in middle-aged and older non-diabetic population: A prospective cohort study
This study aimed to investigate the association between IR measured by the triglyceride-glucose (TyG) index and the risk of stroke among the middle-aged and elderly Chinese without diabetes.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 15, 2023 Category: Nutrition Authors: Yanbo Yu, Ying Meng, Jing Liu Source Type: research
New insights on the cardiovascular effects of IGF-1
DiscussionWe anticipate the development of novel IGF-1-related therapy with minimal side effects. This review discusses recent findings on the role of IGF-1 in the cardiovascular (CVD) system, including both normal and pathological conditions. We also discuss progress in therapeutic interventions aimed at targeting the IGF axis and provide insights into the epigenetic regulation of IGF-1 mediated by microRNAs.
Source: Frontiers in Endocrinology - February 9, 2023 Category: Endocrinology Source Type: research
Cardiovascular complications in insulin resistance and endocrine diseases
Endocr J. 2023 Feb 8. doi: 10.1507/endocrj.EJ22-0457. Online ahead of print.ABSTRACTCerebrovascular diseases, such as stroke and cardiovascular disease, are one of the leading causes of death in Japan. Type 2 diabetes is the most common form of diabetes and an important risk factor for these diseases. Among various pathological conditions associated with type 2 diabetes, insulin resistance has already been reported to be an important risk factor for diabetic complications. The major sites of insulin action in glucose metabolism in the body include the liver, skeletal muscle, and adipose tissue. However, insulin signaling m...
Source: Endocrine Journal - February 8, 2023 Category: Endocrinology Authors: Kyoichiro Tsuchiya Source Type: research
Novel biomarkers and emerging tools to identify causal molecular pathways in hypertension and associated cardiovascular diseases
Kardiol Pol. 2023 Feb 5. doi: 10.33963/KP.a2023.0037. Online ahead of print.ABSTRACTHypertension (HT) is a modifiable risk factor for life-threatening cardiovascular diseases (CVDs) including coronary artery disease, heart failure or stroke. Despite significant progress in understanding of the pathophysiological mechanisms of the disease, the molecular pathways targeted by HT treatment still remain largely unchanged. This warrants the necessity for searching novel biomarkers, which are causally related to persistent high blood pressure (BP) and may be pharmacologically targeted. Data from large-scale biobanks, containing h...
Source: Polish Heart Journal - February 5, 2023 Category: Cardiology Authors: Ewelina J ózefczuk Tomasz J Guzik Mateusz Siedlinski Source Type: research
