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Drug: Botox

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Total 134 results found since Jan 2013.

Management of stroke patients submitted to botulinum toxin type A therapy: a Delphi survey of an Italian expert panel of specialist injectors.
CONCLUSIONS:The results of this national survey confirm that clinical experts on the use of BTX- -A therapy for spasticity after stroke agree on the need to initiate rehabilitation treatment immediately after BTX--A injection: muscle stretching exercises, eventually combined with neuromuscular electrical stimulation, may enhance the effect of BTX--A therapy. Outcome after BTX--A therapy should be assessed at repeated follow--up visits. PMID: 24963604 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - June 19, 2014 Category: Rehabilitation Authors: Franceschini M, Iocco M, Molteni F, Santamato A, Smania N Tags: Eur J Phys Rehabil Med Source Type: research

Adhesive taping vs. daily manual muscle stretching and splinting after botulinum toxin type A injection for wrist and fingers spastic overactivity in stroke patients: a randomized controlled trial.
CONCLUSIONS: Adhesive taping of wrist and finger flexor muscles appeared to enhance the effect of botulinum toxin type A therapy more than daily manual muscle stretching combined with passive articular mobilization and palmar splint. PMID: 24917588 [PubMed - as supplied by publisher]
Source: Clinical Rehabilitation - June 10, 2014 Category: Rehabilitation Authors: Santamato A, Micello MF, Panza F, Fortunato F, Picelli A, Smania N, Logroscino G, Fiore P, Ranieri M Tags: Clin Rehabil Source Type: research

Therapeutic Synergism in the Treatment of Post-stroke Arm Paresis Utilizing Botulinum Toxin, Robotic Therapy, and Constraint-induced Movement Therapy
Botulinum toxin type A (BtxA) injection, constraint-induced movement therapy (CIMT), and robotic therapy (RT) each represent promising approaches to enhance arm motor recovery after stroke. To provide more effective treatment for a 50-year-old man with severe left spastic hemiparesis, we attempted to facilitate CIMT with adaptive approaches to extend the wrist and fingers using RT for 10 consecutive weeks after BtxA injection. This combined treatment resulted in substantial improvements in arm function and the amount of arm use in activities of daily living, and may be effective for stroke patients with severe arm paresis.
Source: PM and R - May 28, 2014 Category: Rehabilitation Authors: Takashi Takebayashi, Satoru Amano, Keisuke Hanada, Atsushi Umeji, Kayoko Takahashi, Tetsuo Koyama, Kazuhisa Domen Tags: Case Presentation Source Type: research

BOTOX(R) (Botulinum Toxin Type A) Receives a Positive Opinion in Fourteen European Countries for the Treatment of Focal Spasticity of the Ankle in Adult Post Stroke Patients
This Positive Opinion Paves the Way for a Second Indication for BOTOX® in Adult Spasticity Associated with Stroke MARLOW, England, May 1, 2014 -- (Healthcare Sales & Marketing Network) --Today, Allergan Inc. announced that BOTOX® has received a... Biopharmaceuticals, RegulatoryAllergan, BOTOX, Adult Spasticity, limb spasticity, stroke
Source: HSMN NewsFeed - May 1, 2014 Category: Pharmaceuticals Source Type: news

Top medicine articles for April 2014
A collection of some interesting medical articles published recently:A Big Bet on Gluten-Free: 11% of households reporting purchases of gluten-free foods in 2013 (doubled in 3 yrs). 30% of the public says it would like to cut back on the amount of gluten it’s eating. "There is a growing population of people who have somehow heard that gluten-free is healthier or think of it as fashionable, and when they remove gluten from their diet, they’re inadvertently taking out a lot of processed foods and are really feeling the benefits of eating healthier foods.” http://buff.ly/1mt9phmNew nomenclature and classifications are p...
Source: Clinical Cases and Images - April 23, 2014 Category: Journals (General) Tags: Health News of the Day Source Type: news

Efficacy of therapeutic ultrasound and transcutaneous electrical nerve stimulation compared with botulinum toxin type a in the treatment of spastic equinus in adults with chronic stroke: a pilot randomized controlled trial.
Conclusions: Our findings support the hypothesis that botulinum toxin type A is more effective than therapeutic ultrasound and TENS for treating focal spasticity in patients with chronic stroke. PMID: 24722047 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - April 17, 2014 Category: Neurology Authors: Picelli A, Dambruoso F, Bronzato M, Barausse M, Gandolfi M, Smania N Tags: Top Stroke Rehabil Source Type: research

Response to IncobotulinumtoxinA After Resistance to OnabotulinumtoxinA and RimabotulinumtoxinB (P7.061)
CONCLUSIONS:Switching to incobotulinumtoxinA after secondary resistance to onabotulinumtoxinA and rimabotulinumtoxinB may be a viable treatment option in dystonia.Study Supported by:National Institutes of Health- National Institutes of Neurological Diseases and Stroke and the Dystonia Medical Research FoundationDisclosure: Dr. Ramos has received personal compensation for activities with the National Inistitutes of Health as an employee, and the Dystonia Medical Research Foundation. Dr. Karp has nothing to disclose. Dr. Lungu has nothing to disclose. Dr. Alter has nothing to disclose. Dr. Hallett has received personal compe...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ramos, V., Karp, B., Lungu, C., Alter, K., Hallett, M. Tags: Movement Disorders: Dystonia Treatment Source Type: research

Cortical Activity Modulation by Botulinum Toxin Type A in Patients with Post-Stroke Arm Spasticity: Real and Imagined Hand Movement (P1.142)
CONCLUSIONS:Study of 2 age-matched groups with mild and severe weakness demonstrated different effect of BoNT-lowered spasticity on motor system engagement. Group A during movement imagery at maximum BoNT effect manifested deactivation of visual and default mode system, perhaps a change from visual to kinesthetic imagery, with cerebellum participating. Group B during movement also manifested motor pattern normalization, especially reduced activation extent.Study Supported by: IGA MH CR grant NT13575.Disclosure: Dr. Hlustik has nothing to disclose. Dr. Veverka has nothing to disclose. Dr. Hok has nothing to disclose. Dr. Tu...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Hlustik, P., Veverka, T., Hok, P., Tudos, Z., Otruba, P., Krobot, A., Kanovsky, P. Tags: Cerebrovascular Disease and Interventional Neurology: Rehabilitation and Recovery Source Type: research

Spinning Out of Control: The Black Box of Basilar and Hemiplegic Migraine (P7.176)
CONCLUSIONS:In this retrospective study, triptans were used effectively with no subsequent vascular events for the abortive treatment of migraines with basilar and hemiplegic features. This data also suggests that beta blockers, tricyclic anti-depressants, anti-convulsants, and Botox injections have some efficacy in the treatment of migraines with basilar type and hemiplegic features.Disclosure: Dr. Krel has nothing to disclose. Dr. Mathew has nothing to disclose. Dr. Spinner has received personal compensation for activities with Merz Pharma and Allergan Inc. as speaker bureau member. Dr. Joshi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Krel, R., Mathew, P., Spinner, W., Joshi, S. Tags: Headache: Treatment Source Type: research

A Compilation of Spasticity Studies Evaluating Onabotulinumtoxin A (P3.042)
CONCLUSIONS: OnabotulinumtoxinA has been extensively studied for treatment of spasticity against a variety of rating scales/assessments and outcomes measures.Study Sponsored by: Allergan, Inc.Disclosure: Dr. Patel has received personal compensation for activities with Allergan Inc. Dr. Manack has received personal compensation for activities with Allergan Inc.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Patel, P., Manack, A. Tags: Neural Repair and Neuro-rehabilitation: Clinical Source Type: research

34. Modulation of cortical activity by botulinum toxin type a in patients with post-stroke arm spasticity
Conclusion: Study of 2 age-matched groups with mild and severe weakness demonstrated different effect of BoNT-lowered spasticity on motor system engagement. Group A during movement imagery at maximum BoNT effect manifested deactivation of visual and default mode system, perhaps a change from visual to kinesthetic imagery, with cerebellum participating. Group B during movement also manifested motor pattern normalization, especially reduced activation extent.Supported by IGA MZ CR NT13575.
Source: Clinical Neurophysiology - April 7, 2014 Category: Neuroscience Authors: P. Hluštík, T. Veverka, P. Hok, Z. Tüdös, P. Otruba, A. Krobot, P. Kaňovský Tags: Society Proceedings Source Type: research

The latest lifeline for patients paralysed by strokes... Botox: Anti-wrinkle jab can help restore lost movement
Lesley Berry, 27, from Walsall, developed dystonia after a stroke and it was only when she started receiving Botox jabs that she bounced back.
Source: the Mail online | Health - March 8, 2014 Category: Consumer Health News Source Type: news

How Botox can help stroke victims: Anti-wrinkle treatment allows paralysed limbs to function better
When injected into the ankle, it eases painful muscle spasms and allows the foot to function more normally.
Source: the Mail online | Health - February 22, 2014 Category: Consumer Health News Source Type: news

Efficacy and safety of botulinum toxin type A (Dysport) for the treatment of post-stroke arm spasticity: Results of the German–Austrian open-label post-marketing surveillance prospective study
Abstract: The current practice in Germany and Austria, and the safety and efficacy of botulinum toxin type A (BoNT-A; Dysport) in the treatment of patients with post-stroke arm spasticity (with no fixed upper-limb contractures), were assessed in this observational prospective non-interventional study. One treatment cycle was documented with assessments at baseline, approximately week 4 (optional), and approximately week 12. Pattern of spasticity, treatment goal, safety and efficacy were recorded. Overall response and goal achievement was rated on a 4-point scale (‘no goal achievement’, ‘goal achievement’, ‘good g...
Source: Journal of the Neurological Sciences - December 23, 2013 Category: Neurology Authors: Wolfgang H. Jost, Harald Hefter, Andrea Reissig, Katja Kollewe, Joerg Wissel Tags: Original Articles Source Type: research