34. Modulation of cortical activity by botulinum toxin type a in patients with post-stroke arm spasticity
Conclusion: Study of 2 age-matched groups with mild and severe weakness demonstrated different effect of BoNT-lowered spasticity on motor system engagement. Group A during movement imagery at maximum BoNT effect manifested deactivation of visual and default mode system, perhaps a change from visual to kinesthetic imagery, with cerebellum participating. Group B during movement also manifested motor pattern normalization, especially reduced activation extent.Supported by IGA MZ CR NT13575.
Source: Clinical Neurophysiology - Category: Neuroscience Authors: P. Hluštík, T. Veverka, P. Hok, Z. Tüdös, P. Otruba, A. Krobot, P. Kaňovský Tags: Society Proceedings Source Type: research
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