Filtered By:
Drug: Botox

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 134 results found since Jan 2013.

Evidence for therapeutic interventions for hemiplegic shoulder pain during the chronic stage of stroke: a review.
CONCLUSIONS: Positive outcomes were noted with the use of corticosteroid injections and electrical stimulation and conflicting results were seen regarding the use of BTx-A. Overall, these targeted therapies provide benefit in the treatment of HSP in individuals who are more than 6 months post stroke. PMID: 23192716 [PubMed - indexed for MEDLINE]
Source: Topics in Stroke Rehabilitation - November 1, 2012 Category: Neurology Authors: Viana R, Pereira S, Mehta S, Miller T, Teasell R Tags: Top Stroke Rehabil Source Type: research

Systematic review of the effectiveness of pharmacological interventions in the treatment of spasticity of the hemiparetic lower extremity more than six months post stroke.
CONCLUSIONS: Pharmacological treatment initiated 6 months post stroke reduced lower limb spasticity. Relevant areas of exploration for future research could include the period of effectiveness, long-term complications, and a cost-benefit analysis of such treatments. PMID: 23192713 [PubMed - indexed for MEDLINE]
Source: Topics in Stroke Rehabilitation - November 1, 2012 Category: Neurology Authors: McIntyre A, Lee T, Janzen S, Mays R, Mehta S, Teasell R Tags: Top Stroke Rehabil Source Type: research

Efficacy of therapeutic ultrasound and transcutaneous electrical nerve stimulation compared with botulinum toxin type a in the treatment of spastic equinus in adults with chronic stroke: a pilot randomized controlled trial.
Conclusions: Our findings support the hypothesis that botulinum toxin type A is more effective than therapeutic ultrasound and TENS for treating focal spasticity in patients with chronic stroke. PMID: 24722047 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - April 17, 2014 Category: Neurology Authors: Picelli A, Dambruoso F, Bronzato M, Barausse M, Gandolfi M, Smania N Tags: Top Stroke Rehabil Source Type: research

Analysis of a 15-years' experience in including shoulder muscles, when treating upper-limb spasticity post-stroke with botulinum toxin type A.
Conclusion When treating ULS, including shoulder muscles, the most frequent goals were IM, PD e MOB. The most injected muscles were SC and PM. The treatment was successful in a large percentage of cases. Achieving the PD goal was associated with greater success at other goals of treatment. BoNTA demonstrated a positive effect in controlling symptoms and improving function. PMID: 29322885 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - January 11, 2018 Category: Neurology Authors: Carvalho MP, Pinto D, Gorayeb M, Jacinto J Tags: Top Stroke Rehabil Source Type: research

Assessing the efficacy of different upper limb hemiparesis interventions on improving health-related quality of life in stroke patients: a systematic review.
CONCLUSION: The review demonstrates the need for upper limb intervention studies to focus on QOL as a primary outcome measure in addition to the functional outcomes currently used. PMID: 23611858 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - March 1, 2013 Category: Neurology Authors: Pulman J, Buckley E Tags: Top Stroke Rehabil Source Type: research

Early versus late injections of Botulinumtoxin type A in post-stroke spastic movement disorder: A literature review
Toxicon. 2023 May 3:107150. doi: 10.1016/j.toxicon.2023.107150. Online ahead of print.ABSTRACTPost-stroke spastic movement disorder (PS-SMD) is one of the main causes of severe disability in the chronic phase after stroke. The prevalence of SMD rises up with time after stroke to more than 28% in the chronic phase, and its secondary complications such as contracture, abnormal postures and/or movement patterns, spasticity-associated pain, also increases with time after stroke when physical and medical management of PS-SMD had been delayed in the early stroke phase. It has been published by several controlled studies that the...
Source: Toxicon - May 5, 2023 Category: Toxicology Authors: J örg Wissel Songjin Ri Anatol Kivi Source Type: research

Botulinum Toxin Type A for the Treatment of Lower Limb Spasticity after Stroke
AbstractPost-stroke lower limb spasticity impairs balance and gait leading to reduced walking speed, often increasing wheelchair use and caregiver burden. Several studies have shown that appropriate treatments for lower limb spasticity after stroke include injections of botulinum toxin type A (BoNT-A), phenol or alcohol, surgical correction and a rehabilitation program. In the present article, we review the safety and effectiveness of BoNT-A for the treatment of lower limb spasticity after stroke, with a focus on higher doses of BoNT-A. The cumulative body of evidence coming from the randomized clinical trials and open-lab...
Source: Drugs - January 8, 2019 Category: Drugs & Pharmacology Source Type: research

Management of stroke patients submitted to botulinum toxin type A therapy: a Delphi survey of an Italian expert panel of specialist injectors.
CONCLUSIONS:The results of this national survey confirm that clinical experts on the use of BTX- -A therapy for spasticity after stroke agree on the need to initiate rehabilitation treatment immediately after BTX--A injection: muscle stretching exercises, eventually combined with neuromuscular electrical stimulation, may enhance the effect of BTX--A therapy. Outcome after BTX--A therapy should be assessed at repeated follow--up visits. PMID: 24963604 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - June 19, 2014 Category: Rehabilitation Authors: Franceschini M, Iocco M, Molteni F, Santamato A, Smania N Tags: Eur J Phys Rehabil Med Source Type: research

Plastic changes in spinal synaptic transmission following botulinum toxin A in patients with post-stroke spasticity.
CONCLUSION: Botulinum toxin treatment induces synaptic plasticity at the Ia-motoneuron synapse in post-stroke paretic patients, which suggests that the effectiveness of botulinum toxin-type A in post-stroke rehabilitation might be partly due to its central effects. PMID: 26424152 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - October 3, 2015 Category: Rehabilitation Tags: J Rehabil Med Source Type: research

Efficacy and safety of Botulinum Toxin type A for upper limb spasticity after stroke or traumatic brain injury: a systematic review with meta-analysis and trial sequential analysis.
CONCLUSIONS: As compared with placebo, Botulinum Toxin type A injections have beneficial effects with improved muscle tone and well-tolerated treatment for patients with upper limb spasticity post stroke or traumatic brain injury. PMID: 27834471 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - November 10, 2016 Category: Rehabilitation Authors: Dong Y, Wu T, Hu X, Wang T Tags: Eur J Phys Rehabil Med Source Type: research

The Italian real-life post-stroke spasticity survey: unmet needs in the management of spasticity with botulinum toxin type A.
Authors: Picelli A, Baricich A, Cisari C, Paolucci S, Smania N, Sandrini G Abstract The present national survey seeking to identify unmet needs in the management of spasticity with botulinum toxin type A focused on the use of OnabotulinumoxinA, since this is the brand with the widest range of licensed indications in Italy. Physicians from twenty-four Italian neurorehabilitation units compiled a questionnaire about "real-life" post-stroke spasticity management. OnabotulinumtoxinA was reported to be used in the following average doses: upper limb 316.7 ± 79.1 units; lower limb 327.8 ± 152.3; upper and lower limb 54...
Source: Functional Neurology - July 7, 2017 Category: Neurology Tags: Funct Neurol Source Type: research

Evaluating the functional outcomes of ultrasound-guided botulinum toxin type A injections using the Euro-musculus approach for upper limb spasticity treatment in post-stroke patients; an observational study.
CONCLUSIONS: Ultrasound-guided botulinum toxin type A injection via the Euro- musculus spasticity approach is a practical and effective method for administering injections to the correct point of the correct muscle. Ultrasound-guided botulinum toxin type A injections combined with rehabilitation programmes decrease spasticity and improve the upper extremity motor functions in stroke patients. CLINICAL REHABILITATION IMPACT: This new approach for ultrasound- guided botulinum toxin type A injection is very practical and effective method for upper extremity spasticity. PMID: 29422486 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - February 7, 2018 Category: Rehabilitation Authors: Buyukavci R, Akturk S, Ersoy Y Tags: Eur J Phys Rehabil Med Source Type: research

Management of spasticity with onabotulinumtoxinA: practical guidance based on the italian real-life post-stroke spasticity survey.
Authors: Sandrini G, Baricich A, Cisari C, Paolucci S, Smania N, Picelli A Abstract The present paper provides practical guidance on the management of adult spasticity with OnabotulinumtoxinA. Advisory Board members reviewed the available evidence and discussed their personal experiences in order to address the unmet needs in the management of spasticity with botulinum toxin type A identified by the recent Italian Real-Life Post-Stroke Spasticity Survey. Stroke patients should be referred to spasticity services that have adequate facilities and multidisciplinary teams with the necessary training, competence and exp...
Source: Functional Neurology - April 12, 2018 Category: Neurology Tags: Funct Neurol Source Type: research

Botulinum toxin use in patients with post-stroke spasticity: a nationwide retrospective study from France
ConclusionOur analysis of the exhaustive PMSI database showed a suboptimal implementation of BoNT-A treatment recommendations in France. BoNT-A treatment initiation and re-administration are low, particularly in patients with post-stroke spasticity. Further investigations may help explain this observation, and may target specific actions to improve spasticity-related care pathway.
Source: Frontiers in Neurology - August 23, 2023 Category: Neurology Source Type: research