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Condition: Ischemic Stroke
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Total 575 results found since Jan 2013.

Transcatheter closure of patent foramen ovale for secondary prevention of ischemic stroke: Quantitative synthesis of pooled randomized trial data
ConclusionsBased on the results of this analysis of randomized trial data, percutaneous PFO closure appears to be a safe and effective therapeutic option for the secondary prevention of ischemic stroke in patients with PFO and cryptogenic stroke.
Source: Catheterization and Cardiovascular Interventions - January 14, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Abdul Hakeem, Mehmet Cilingiroglu, Angelos Katramados, Konstantinos Dean Boudoulas, Cezar Iliescu, Betul Gundogdu, Konstantinos Marmagkiolis Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

A new era in stroke care gives larger treatment window and better outcomes
According to the American Heart/American Stroke Association, stroke affects nearly 800,000 people in the United States each year. It is the fifth leading cause of death, and the leading cause of long-term disability.  It’s also the leading cause of preventable disability. In China it is the leading cause of death surpassing both cancer and heart disease. Stroke occurs when a blood vessel carrying oxygen and nutrients to the brain is either blocked by a blood clot or plaque (ischemic stroke), or…
Source: bizjournals.com Health Care News Headlines - August 15, 2018 Category: Health Management Authors: Alexandria Foley Source Type: news

Novel Use of a Nurse-Led Telemedicine Team in Acute Stroke: A Retrospective Review of the Impact on a Regional Health Care System
Despite the increasing incidence of acute ischemic stroke in the United States, many health care facilities remain unprepared to manage patients with acute stroke, including the administration of intravenous alteplase (recombinant tissue plasminogen activator [rTPA]). This has led to an opportunity for telemedicine systems to facilitate these evaluations and acute medical stroke treatment decisions. However, even telemedicine systems can fail to provide timely evaluation and management of the patient with acute stroke.
Source: Journal of Emergency Nursing: JEN - September 5, 2018 Category: Nursing Authors: Susan B. Fowler, Christian A. Rosado, Jennifer Jones, Suzanne Ashworth, Darlene Adams Tags: Clinical Article Source Type: research

Occupational and leisure-time physical activity differentially predict 6-year incidence of stroke and transient ischemic attack in women
Conclusions Higher intensity levels of OPA increased stroke and TIA risks, while LTPA decreased risks; results corroborate the physical activity health paradox for women and cerebrovascular disease. More standing at work increased cerebrovascular disease risks, especially for women with CVD.byHall C, Heck JE, Sandler DP, Ritz B, Chen H, Krause N. doi:10.5271/sjweh.3786
Source: Scandinavian Journal of Work, Environment and Health - November 18, 2018 Category: Occupational Health Tags: Original article Source Type: research

Anesthetic Management of Emergency Endovascular Thrombectomy for Acute Ischemic Stroke, Part 1: Patient Characteristics, Determinants of Effectiveness, and Effect of Blood Pressure on Outcome.
Abstract In the United States, stroke ranks fifth among all causes of death and is the leading cause of serious long-term disability. The 2018 American Heart Association stroke care guidelines consider endovascular thrombectomy to be the standard of care for patients who have acute ischemic stroke in the anterior circulation when arterial puncture can be made within 6 hours of symptom onset or within 6-24 hours of symptom onset when specific eligibility criteria are satisfied. The aim of this 2-part review is to provide practical perspective on the clinical literature regarding anesthesia care of patients treated ...
Source: Anesthesia and Analgesia - March 20, 2019 Category: Anesthesiology Authors: Hindman BJ Tags: Anesth Analg Source Type: research

Causes of Acute Stroke: A Patterned Approach.
This article reviews the imaging patterns of acute strokes, and how the infarct pattern and imaging characteristics can suggest an underlying cause. PMID: 31582037 [PubMed - in process]
Source: Radiologic Clinics of North America - October 5, 2019 Category: Radiology Authors: Knight-Greenfield A, Nario JJQ, Gupta A Tags: Radiol Clin North Am Source Type: research

Indications and Evidence for Dual Antiplatelet Therapy After Acute Ischemic Stroke
The antiplatelet landscape for the secondary prevention of ischemic stroke has changed significantly over the past decade. Poststroke dual antiplatelet regimens are becoming increasingly routine as supported by recent literature and guideline recommendations. Dual antiplatelet therapy after stroke generally consists of aspirin and clopidogrel and is considered in the short term after stroke in select populations including those with mild stroke or transient ischemic attack and in patients with severe intracranial atherosclerosis. When initiating dual antiplatelet therapy, factors that may increase a patient's risk of bleed...
Source: Critical Care Nursing Quarterly - February 22, 2020 Category: Nursing Tags: Original Articles Source Type: research

Monoclonal antibody as an emerging therapy for acute ischemic stroke.
Authors: Woods D, Jiang Q, Chu XP Abstract Acute ischemic stroke (AIS) is the 5th leading cause of death and the leading cause of neurological disability in the United States. The oxygen and glucose deprivation associated with AIS not only leads to neuronal cell death, but also increases the inflammatory response, therefore decreasing the functional outcome of the brain. The only pharmacological intervention approved by the US Federal Food and Drug Administration for treatment of AIS is tissue plasminogen activator (t-PA), however, such treatment can only be given within 4.5 hours of the onset of stroke-like sympto...
Source: International Journal of Physiology, Pathophysiology and Pharmacology - September 18, 2020 Category: Physiology Tags: Int J Physiol Pathophysiol Pharmacol Source Type: research

Sex Differences in Prehospital Delay in Patients With Acute Stroke: A Systematic Review
Conclusions Most study authors found no differences in prehospital delay between women and men; however, women delayed longer in some Asian-Pacific and American studies. Findings of sex differences were inconclusive.
Source: Journal of Cardiovascular Nursing - October 21, 2020 Category: Nursing Tags: Feature Article/Online Only Source Type: research

Stroke Treatment With PAR-1 Agents to Decrease Hemorrhagic Transformation
Ischemic stroke is the most widespread cause of disability and a leading cause of death in developed countries. To date, the most potent approved treatment for acute stroke is recanalization therapy with thrombolytic drugs such as tissue plasminogen activator (rt-PA or tPA) or endovascular mechanical thrombectomy. Although tPA and thrombectomy are widely available in the United States, it is currently estimated that only 10–20% of stroke patients get tPA treatment, in part due to restrictive selection criteria. Recently, however, tPA and thrombectomy selection criteria have loosened, potentially allowing more patients to...
Source: Frontiers in Neurology - March 15, 2021 Category: Neurology Source Type: research

Meta-Analysis of Racial Disparity in Utilization of Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation
Atrial fibrillation (AF) is the most common arrhythmia in the United States (US), and is associated with a substantial increase in the risk of ischemic stroke. Although prevalence of AF is lower in black individuals, they face a higher risk of stroke compared with patients of white race.1 Oral anticoagulant (OAC) therapy is the stroke prevention strategy in high-risk patients with AF. Despite the higher burden of ischemic stroke in Black AF patients, some studies suggest lower utilization of OAC among them.
Source: The American Journal of Cardiology - June 17, 2021 Category: Cardiology Authors: Izza Shahid, Muhammad Shariq Usman, Tariq Jamal Siddiqi, Faiza Zakaria, Mohamad Alkhouli Source Type: research

O-016 Aspiration thrombectomy for acute ischemic stroke patients presenting after 6 hours
ConclusionFor patients with late presentation stroke, aspiration thrombectomy with the Penumbra System in anterior circulations is safe and effective. Rates of good functional outcome and all-cause mortality compare favorably to the DAWN and DEFUSE-3 medical management arms.Disclosures A. Hassan: 2; C; GE Healthcare, Genentech, Medtronic, Microvention, Penumbra, Stryker, Cerenovus, Viz.ai, Balt, Scientia. 3; C; GE Healthcare, Genentech, Medtronic, Microvention, Penumbra, Stryker, Cerenovus, Viz.ai, Balt, Scientia. J. Fifi: 1; C; Microvention, Penumbra, Stryker. 2; C; Microvention, Stryker. 4; C; Imperative Care. O. Zaidat:...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Hassan, A., Fifi, J., Zaidat, O. Tags: Oral abstracts Source Type: research

Rural-Urban Disparities in Outcomes of Myocardial Infarction, Heart Failure, and Stroke in the United States
CONCLUSIONS: Clinical, public health, and policy efforts are needed to improve rural-urban gaps in care and outcomes for acute cardiovascular conditions.PMID:35057913 | DOI:10.1016/j.jacc.2021.10.045
Source: Rural Remote Health - January 21, 2022 Category: Rural Health Authors: Em éfah C Loccoh Karen E Joynt Maddox Yun Wang Dhruv S Kazi Robert W Yeh Rishi K Wadhera Source Type: research

Mechanical thrombectomy beyond the circle of Willis: efficacy and safety of different techniques for M2 occlusions
Conclusion Stent-retrievers and a combined approach for M2 occlusions seem more effective than direct aspiration, but with higher rates of iSAH. This leads to no detectable difference in clinical outcome at 3 months.
Source: Journal of NeuroInterventional Surgery - May 13, 2022 Category: Neurosurgery Authors: Renieri, L., Valente, I., Dmytriw, A. A., Puri, A. S., Singh, J., Nappini, S., Nencini, P., Kaliaev, A., Abdalkader, M., Alexandre, A., Garignano, G., Vivekanandan, S., Fong, R. P., Parra-Farinas, C., Spears, J., Gomez-Paz, S., Ogilvy, C., Regenhardt, R. Tags: Ischemic stroke Source Type: research