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Condition: Ischemic Stroke
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Total 575 results found since Jan 2013.

Arsenic Exposure in Relation to Ischemic Stroke Clinical Sciences
Conclusions—A metabolite of arsenic was positively associated with incident ischemic stroke in this case–cohort study of the US general population, a low-to-moderate exposure area. Overall, these findings suggest a potential role for arsenic methylation in the pathogenesis of stroke, having important implications for future cerebrovascular research.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Cari L. Tsinovoi, Pengcheng Xun, Leslie A. McClure, Vivian M.O. Carioni, John D. Brockman, Jianwen Cai, Eliseo Guallar, Mary Cushman, Frederick W. Unverzagt, Virginia J. Howard, Ka He Tags: Epidemiology, Risk Factors, Ischemic Stroke Original Contributions Source Type: research

Palliative Care for Hospitalized Patients With Stroke Clinical Sciences
This study explores patterns of palliative care utilization and death in hospitalized patients with stroke across the United States.Methods—Using the 2010 to 2012 nationwide inpatient sample databases, we included all patients discharged with stroke identified by International Classification of Diseases-Ninth Revision codes. Strokes were subclassified as ischemic, intracerebral, and subarachnoid hemorrhage. We compared demographics, comorbidities, procedures, and outcomes between patients with and without a palliative care encounter (PCE) as defined by the International Classification of Diseases-Ninth Revision code V66....
Source: Stroke - August 28, 2017 Category: Neurology Authors: Tarvinder Singh, Steven R. Peters, David L. Tirschwell, Claire J. Creutzfeldt Tags: Race and Ethnicity, Quality and Outcomes, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Minimal Clinically Important Difference for Safe and Simple Novel Acute Ischemic Stroke Therapies Clinical Sciences
Conclusions—Stroke expert responses to MCID surveys are affected by anchoring and centrality bias. When survey design takes these into account, the expert-derived MCID for a safe acute ischemic stroke treatment is 1.1% to 1.5%, in accord with actual physician behavior in guideline writing and clinical practice. This revised MCID value can guide clinical trial design and grant-funding and regulatory agency decisions.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Jessica S. Cranston, Brett D. Kaplan, Jeffrey L. Saver Tags: Ischemic Stroke, Neuroprotectants Original Contributions Source Type: research

Comorbid Psychiatric Disease Is Associated With Lower Rates of Thrombolysis in Ischemic Stroke Brief Report
Background and Purpose—Intravenous thrombolysis (IVT) improves outcomes after acute ischemic stroke but is underused in certain patient populations. Mental illness is pervasive in the United States, and patients with comorbid psychiatric disease experience inequities in treatment for a range of conditions. We aimed to determine whether comorbid psychiatric disease is associated with differences in IVT use in acute ischemic stroke.Methods—Acute ischemic stroke admissions between 2007 and 2011 were identified in the Nationwide Inpatient Sample. Psychiatric disease was defined by International Classification of Diseases, ...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Diana M. Bongiorno, Gail L. Daumit, Rebecca F. Gottesman, Roland Faigle Tags: Quality and Outcomes, Ischemic Stroke Brief Reports Source Type: research

Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke Clinical Sciences
Conclusions—This largest-to-date Solitaire registry documents that the results of the randomized trials can be reproduced in the community. The decrease of clinical benefit over time warrants optimization of the system of care.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT02239640.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Nils H. Mueller-Kronast, Osama O. Zaidat, Michael T. Froehler, Reza Jahan, Mohammad Ali Aziz-Sultan, Richard P. Klucznik, Jeffrey L. Saver, Frank R. Hellinger Jr, Dileep R. Yavagal, Tom L. Yao, David S. Liebeskind, Ashutosh P. Jadhav, Rishi Gupta, Ameer E Tags: Revascularization, Ischemic Stroke Original Contributions Source Type: research

Stroke Legislation Impacts Distribution of Certified Stroke Centers in the United States Clinical Sciences
Conclusions— State stroke legislation, a generalizable intervention, increased the number of certified stroke centers in the United States, potentially improving accessibility of standardized care for patients with acute ischemic stroke.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Uchino, K., Man, S., Schold, J. D., Katzan, I. L. Tags: Health policy and outcome research Clinical Sciences Source Type: research

Diet Beverages Linked To Increased Stroke Risk & Heart Attacks
This study, as well as other research on the connection between diet beverages and vascular disease, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage or another hidden health issue. “Postmenopausal women tend to have higher risk for vascular disease because they are lacking the protective effects of natural hormones,” North Carolina cardiologist Dr. Kevin Campbell said, which could contribute to increased risk for heart disease and stroke...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Heart Attack Stroke Source Type: news

Diet Drinks Linked To Increased Stroke Risk & Heart Attacks
This study, as well as other research on the connection between diet beverages and vascular disease, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage or another hidden health issue. “Postmenopausal women tend to have higher risk for vascular disease because they are lacking the protective effects of natural hormones,” North Carolina cardiologist Dr. Kevin Campbell said, which could contribute to increased risk for heart disease and stroke...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Heart Attack Stroke Source Type: news

Comparison of Acute Ischemic Stroke Care and Outcomes Between Comprehensive Stroke Centers and Primary Stroke Centers in the United States Original Articles
Conclusions: CSCs and PSCs achieved similar overall care quality for patients with acute ischemic stroke. CSCs exceeded PSCs in timely acute reperfusion therapy for emergency department admissions, whereas PSCs had lower risk-adjusted in-hospital mortality. This information may be important for acute stroke triage and targeted quality improvement.
Source: Circulation: Cardiovascular Quality and Outcomes - May 23, 2018 Category: Cardiology Authors: Man, S., Zhao, X., Uchino, K., Hussain, M. S., Smith, E. E., Bhatt, D. L., Xian, Y., Schwamm, L. H., Shah, S., Khan, Y., Fonarow, G. C. Tags: Quality and Outcomes, Ischemic Stroke Original Articles Source Type: research

Duration of symptomatic stroke and successful reperfusion with endovascular thrombectomy for anterior circulation large vessel occlusive stroke
Conclusion In a real-world cohort of acute ischemic stroke patients with anterior circulation occlusion treated with endovascular therapy, longer duration of symptomatic stroke is associated with lower rates of successful reperfusion and reperfusion on the first pass.
Source: Journal of NeuroInterventional Surgery - November 18, 2021 Category: Neurosurgery Authors: de Havenon, A., Alexander, M. D., Nogueira, R. G., Haussen, D. C., Castonguay, A. C., Linfante, I., Johnson, M. A., Nguyen, T. N., Mokin, M., Zaidat, O. O. Tags: Ischemic stroke Source Type: research

Cryptogenic stroke: Contemporary trends, treatments, and outcomes in the United States
Conclusions In a large contemporary nationwide registry, CS accounted for 20% of ISs among patients with a documented stroke etiology. Patients with CS had a distinct profile of treatments and outcomes relative to other subtypes. Improved subtype documentation and further research into CS are warranted to improve care and outcomes for patients with stroke.
Source: Neurology Clinical Practice - October 12, 2020 Category: Neurology Authors: Prabhakaran, S., Messe, S. R., Kleindorfer, D., Smith, E. E., Fonarow, G. C., Xu, H., Zhao, X., Lytle, B., Cigarroa, J., Schwamm, L. H. Tags: All Cerebrovascular disease/Stroke Research Source Type: research

Mechanical Thrombectomy in Ischemic Stroke Patients with Severe Pre-Stroke Disability
Frequency and outcomes of mechanical thrombectomy (MT) in clinical practice for patients with severe pre-stroke disability are largely unknown. In this case series, we aim to describe the disability make-up and outcomes of 33 patients with severe pre-stroke disability undergoing MT. Patients with a permanent, severe, pre-stroke disability (modified Rankin Score, mRS, 4-5) were identified from a prospectively-maintained database of consecutive, MT-treated, anterior circulation acute ischemic stroke patients at two comprehensive stroke centers in the United States.
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: Sanjana Salwi, Shawna Cutting, Alan D. Salgado, Kiersten Espaillat, Matthew R. Fusco, Michael T. Froehler, Rohan V. Chitale, Howard Kirshner, Matthew Schrag, Adam Jasne, Tina Burton, Brian Mac Grory, Ali Saad, Mahesh V. Jayaraman, Tracy E. Madsen, Katarin Source Type: research

Travel time and distance for bypass and non-bypass routing of stroke patients in the USA
Conclusions Bypass routing offers modest travel time benefits for LVO patients and incurs modest penalties for non-LVO patients. Differences are greatest in rural areas. A majority of Americans live in areas for which current guidelines recommend bypass.
Source: Journal of NeuroInterventional Surgery - June 16, 2023 Category: Neurosurgery Authors: Yu, C. Y., Panagos, P. D., Kansagra, A. P. Tags: Ischemic stroke Source Type: research

First Pass Effect Clinical Sciences
Conclusions—The achievement of complete revascularization from a single Solitaire thrombectomy device pass (FPE) is associated with significantly higher rates of good clinical outcome. The FPE is more frequently associated with the use of balloon guide catheters and less likely to be achieved with internal carotid artery terminus occlusion.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Osama O. Zaidat, Alicia C. Castonguay, Italo Linfante, Rishi Gupta, Coleman O. Martin, William E. Holloway, Nils Mueller-Kronast, Joey D. English, Guilherme Dabus, Tim W. Malisch, Franklin A. Marden, Hormozd Bozorgchami, Andrew Xavier, Ansaar T. Rai, Mich Tags: Ischemic Stroke Original Contributions Source Type: research

Rates of adverse events in patients with ischemic stroke treated at thrombectomy capable hospitals
Conclusions A decrease in-hospital adverse events and improved discharge outcomes were observed among patients with ischemic stroke admitted to a TCH compared with a non-TCH.
Source: Journal of NeuroInterventional Surgery - March 18, 2022 Category: Neurosurgery Authors: Chaudhry, S. A., Sadaf, H., Laleka, I., Nasir, W., Witzel, C., Bahiru, Z., Fang, Y., Ishfaq, F., Altaweel, L. R., Qureshi, A. I. Tags: Ischemic stroke Source Type: research