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Total 465 results found since Jan 2013.

Childhood and Adolescent Adversity and Cardiometabolic Outcomes: A Scientific Statement From the American Heart Association.
Cardiovascular Disease in the Young; Council on Functional Genomics and Translational Biology; Council on Cardiovascular and Stroke Nursing; and Council on Quality of Care and Outcomes Research Abstract Adverse experiences in childhood and adolescence, defined as subjectively perceived threats to the safety or security of the child's bodily integrity, family, or social structures, are known to be associated with cardiometabolic outcomes over the life course into adulthood. This American Heart Association scientific statement reviews the scientific literature on the influence of childhood adversity on cardiometabo...
Source: Circulation - December 18, 2017 Category: Cardiology Authors: Suglia SF, Koenen KC, Boynton-Jarrett R, Chan PS, Clark CJ, Danese A, Faith MS, Goldstein BI, Hayman LL, Isasi CR, Pratt CA, Slopen N, Sumner JA, Turer A, Turer CB, Zachariah JP, American Heart Association Council on Epidemiology and Prevention; Council o Tags: Circulation Source Type: research

Alcohol and CV Health: Jekyll and Hyde J-Curves
A routine of light or moderate alcohol consumption ( ≤1 drink/day for women and 1 to 2 drinks/day for men) were associated with a lower risk for all-cause mortality, coronary artery disease (CAD), type 2 diabetes mellitus (T2D), heart failure (HF), and stroke. Conversely, heavy drinking, (>4 drinks/day) is associated with an increased risk for death and cardiovascular (CV) disease (CVD). Excessive alcohol intake trails behind only smoking and obesity among the 3 leading causes of premature deaths in the United States (US).
Source: Progress in Cardiovascular Diseases - February 17, 2018 Category: Cardiology Authors: Evan L. O'Keefe, James J. Di Nicolantonio, James H. O'Keefe, Carl J. Lavie Source Type: research

Usefulness of alirocumab and evolocumab for the treatment of patients with diabetic dyslipidemia.
Abstract In 2015, the US Food and Drug Administration (FDA) approved the anti-proprotein convertase subtilsin/kexin type 9 (PCSK9) monoclonal antibodies, alirocumab and evolocumab, to treat patients with hypercholesterolemia and mixed dyslipidemia. Since then, considerable attention has been paid to the use of these monoclonal antibodies for the treatment of diabetic dyslipidemia with a goal of reducing the risk for cardiovascular disease. Recently, consensus statements on the clinical use of PCSK9 inhibitors in patients with type 2 diabetes mellitus, who are unable to achieve the goal of low-density lipoprotein c...
Source: Baylor University Medical Center Proceedings - April 1, 2018 Category: Universities & Medical Training Authors: Zhang J, Tecson KM, Rocha NA, McCullough PA Tags: Proc (Bayl Univ Med Cent) Source Type: research

Diabetes Risk Scores for Hispanics Living in the United States.: A systematic review
The prevalence of diabetes is increasing worldwide [1 –3]. Diabetes and its vascular complications are the seventh leading cause of disability worldwide and contribute to the deaths of two million adults per year [4]. Type 2 diabetes is the most common type affecting 90-95% of those with diabetes and may be asymptomatic for years [5]. Uncontrolled di abetes leads to microvascular (e.g., neuropathy, nephropathy, retinopathy) and macrovascular (e.g., myocardial infarction, stroke) complications and may increase mortality risk [6,7].
Source: Diabetes Research and Clinical Practice - May 28, 2018 Category: Endocrinology Authors: Lucia D. Juarez, Jeffrey S. Gonzalez, April A. Agne, Andrzej Kulczycki, Gregory Pavela, April P. Carson, John P. Shelley, Andrea L. Cherrington Source Type: research

Health Tip: 4 Steps to Manage Diabetes
-- Every year, 1.7 million people in the United States are diagnosed with diabetes, the U.S. National Institutes of Health says. Left untreated, diabetes can lead to heart disease, stroke, kidney disease, blindness and other health problems, the...
Source: Drugs.com - Daily MedNews - June 14, 2018 Category: General Medicine Source Type: news

Surveillance for Certain Health Behaviors and Conditions Among States and Selected Local Areas - Behavioral Risk Factor Surveillance System, United States, 2015.
This report presents results for all 50 states, the District of Columbia, the Commonwealth of Puerto Rico (Puerto Rico), and Guam and for 130 metropolitan and micropolitan statistical areas (MMSAs) (N = 441,456 respondents) for 2015. RESULTS: The age-adjusted prevalence estimates of health-risk behaviors, self-reported chronic health conditions, access to and use of health care, and use of preventive health services varied substantially by state, territory, and MMSA in 2015. Results are summarized for selected BRFSS measures. Each set of proportions refers to the median (range) of age-adjusted prevalence estimates for...
Source: MMWR Surveill Summ - June 29, 2018 Category: Epidemiology Authors: Pickens CM, Pierannunzi C, Garvin W, Town M Tags: MMWR Surveill Summ Source Type: research

Diabetes risk scores for Hispanics living in the United States: A systematic review
The prevalence of diabetes is increasing worldwide [1 –3]. Diabetes and its vascular complications are the seventh leading cause of disability worldwide and contribute to the deaths of two million adults per year [4]. Type 2 diabetes is the most common type affecting 90–95% of those with diabetes and may be asymptomatic for years [5]. Uncontrolled diabetes leads to microvascular (e.g., neuropathy, nephropathy, retinopathy) and macrovascular (e.g., myocardial infarction, stroke) complications and may increase mortality risk [6,7].
Source: Diabetes Research and Clinical Practice - May 28, 2018 Category: Endocrinology Authors: Lucia D. Juarez, Jeffrey S. Gonzalez, April A. Agne, Andrzej Kulczycki, Gregory Pavela, April P. Carson, John P. Shelley, Andrea L. Cherrington Source Type: research

Design and baseline characteristics of the eValuation of ERTugliflozin effIcacy and safety CardioVascular outcomes trial (VERTIS-CV)
ConclusionThe results from the VERTIS-CV trial will define the CV and renal safety and efficacy of ertugliflozin in patients with T2DM and ASCVD.ClinicalTrials.gov identifier: NCT01986881
Source: American Heart Journal - September 6, 2018 Category: Cardiology Source Type: research

A nonrestrictive, weight loss diet focused on fiber and lean protein increase
According to the World Health Organization, more than 1.9 billion adults age ≥18 year were overweight and more than 600 million adults obese worldwide in 2014 [1]. Excess weight significantly increases the risk for morbidity including hypertension, stroke, cardiovascular disease, type 2 diabetes, osteoarthritis, and some types of cancers [2,3]. In the United States, obesit y remains a leading public health problem with 34.9% of adults and 16.9% of children who were obese between 2011 and 2012 [4].
Source: Nutrition - March 22, 2018 Category: Nutrition Authors: Lijuan Zhang, Sherry Pagoto, Barbara Olendzki, Gioia Persuitte, Linda Churchill, Jessica Oleski, Yunsheng Ma Tags: Applied nutritional investigation Source Type: research

Prevalence of Total, Diagnosed, and Undiagnosed Diabetes Among Adults: United States, 2013-2016.
This report presents the prevalence of total, diagnosed, and undiagnosed diabetes in U.S. adults in 2013-2016. PMID: 30248004 [PubMed - in process]
Source: NCHS data brief - September 26, 2018 Category: American Health Tags: NCHS Data Brief Source Type: research

Cardiovascular risk profiles in Type 2 diabetes and the impact of geographical setting.
Authors: Smith-Palmer J, Boye KS, Perez-Nieves M, Valentine W, Bae JP Abstract Cardiovascular (CV) disease is a leading morbidity and mortality in Type 2 diabetes (T2DM). Previous studies have shown geographic differences in the prevalence of CV and renal diseases. A literature review of longitudinal (≥5 years) studies including ≥1000 T2DM patients and reporting CV endpoints was performed to compare risk profiles. Key differences between geographies included a relatively higher prevalence of microalbuminuria in East Asian relative to North American and European patients, which in turn is an important CV risk fa...
Source: Expert Review of Endocrinology and Metabolism - October 11, 2018 Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research

National Diabetes Month - November 2018.
Authors: Abstract November is National Diabetes Month. In the United States, approximately 30 million persons are living with diabetes and 84 million with prediabetes (1). Persons with prediabetes are at high risk for developing type 2 diabetes, heart disease, and stroke (2). Likewise, women who have had gestational diabetes (diabetes during pregnancy) are at increased risk for developing type 2 diabetes later in life (2). However, type 2 diabetes can be prevented or delayed through a structured lifestyle change program that promotes weight loss, healthy eating, and increased physical activity (2). A report on ch...
Source: MMWR Morb Mortal Wkl... - November 2, 2018 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: research

A Clinical Prescription for Heart Health in Midlife Women
Heart disease remains the leading cause of death in women in Europe and the United States with the incidence increasing during midlife. [1] While one in thirty-one women will die from breast cancer, one in approximately two to three women will die from heart disease or stroke. [1,2], While most women are aware about traditional cardiovascular disease (CVD) risk factors, such as hypertension, dyslipidemia and diabetes, they are often unaware of sex specific risk factors that occur in midlife. [3] Clinical risk factors can vary depending on the individual personal family history and can change as a woman ages.
Source: Maturitas - November 12, 2018 Category: Primary Care Authors: Chrisandra Shufelt, Erika Dutra, Tina Torbati, Tina Ramineni Source Type: research

Type 2 Diabetes Mellitus in Patients with Sickle Cell Disease: A Population-Based Longitudinal Analysis of Three Cohorts
ConclusionWe present evidence describing the prevalence of T2DM in patients with SCD both in a commercially-insured population and from an institution-based clinical cohort. These findings were similar to a general African American population with an increasing trend in T2DM over recent years. These trends support the routine screening for T2DM in patients with SCD, especially those of older age and with presence of comorbid hypertension and/or dyslipidemia.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - November 21, 2018 Category: Hematology Authors: Zhou, J., Han, J., Nutescu, E. A., Galanter, W., Walton, S. M., Gordeuk, V. R., Saraf, S. L., Srisuwananukorn, A., Calip, G. S. Tags: 903. Outcomes Research-Non-Malignant Hematology: Poster III Source Type: research