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Total 276 results found since Jan 2013.

Impact of a Structured Response and Evidence-Based Checklist on In-hospital Stroke Outcomes
CONCLUSIONS Use of a checklist during inpatient stroke events can potentially increase adherence to guidelines for appropriate treatment and reduce mortality. Hospital response teams should consider use of a structured response system with an evidence-based checklist for high-acuity, low-frequency events such as in-hospital stroke.
Source: Journal of Neuroscience Nursing - April 29, 2020 Category: Neuroscience Tags: Article Source Type: research

Neuroprotective and neuro-rehabilitative effects of acute purinergic receptor P2X4 (P2X4R) blockade after ischemic stroke.
Abstract Stroke remains a leading cause of disability in the United States. Despite recent advances, interventions to reduce damage and enhance recovery after stroke are lacking. P2X4R, a receptor for adenosine triphosphate (ATP), regulates activation of myeloid immune cells (infiltrating monocytes/macrophages and brain-resident microglia) after stroke injury. However, over-stimulation of P2X4Rs due to excessive ATP release from dying or damaged neuronal cells can contribute to ischemic injury. Therefore, we pharmacologically inhibited P2X4R to limit the over-stimulated myeloid cell immune response and improve bot...
Source: Experimental Neurology - April 10, 2020 Category: Neurology Authors: Srivastava P, Cronin CG, Scranton VL, Jacobson KA, Liang BT, Verma R Tags: Exp Neurol Source Type: research

GSE107983 Ischemia/Reperfusion Induces Interferon-Stimulated Gene Expression in Microglia
Contributors : Ashley McDonough ; Richard V Lee ; Shahani Noor ; Chungeun Lee ; Thu Le ; Michael Iorga ; Jessica L Phillips ; Sean Murphy ; Thomas M öller ; Jonathan R WeinsteinSeries Type : Expression profiling by arrayOrganism : Mus musculusStroke is the fifth leading cause of death in the United States and is a leading cause of serious long-term disability worldwide. Innate immune responses are critical in stroke pathophysiology, and microglia are key cellular effectors in the CNS response to ischemia/reperfusion. Using a transcriptional analysis approach, we identified a robust interferon (IFN)-stimulated gene respons...
Source: GEO: Gene Expression Omnibus - April 1, 2020 Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research

Management of Spasticity After Traumatic Brain Injury in Children
Traumatic brain injury is a common cause of disability worldwide. In fact, trauma is the second most common cause of death and disability, still today. Traumatic brain injury affects nearly 475 000 children in the United States alone. Globally it is estimated that nearly 2 million people are affected by traumatic brain injuries every year. The mechanism of injury differs between countries in the developing world, where low velocity injuries and interpersonal violence dominates, and high-income countries where high velocity injuries are more common. Traumatic brain injury is not only associated with acute problems, but pati...
Source: Frontiers in Neurology - February 20, 2020 Category: Neurology Source Type: research

Spirituality and resilience among family  caregivers of survivors of stroke: A scoping review.
CONCLUSIONS: Spirituality and resilience following stroke are essential factors in caregiver adjustment following stroke. Further research with a focus on causality and the link between spirituality, resilience and adjustment in this population is needed. PMID: 32039873 [PubMed - as supplied by publisher]
Source: NeuroRehabilitation - February 11, 2020 Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research

Dimensions of post-stroke depression and neuropsychological deficits in older adults
Stroke is the leading cause of both serious and long-term disability and the fifth leading cause of death in the United States.1,2 Post-stroke depression (PSD) afflicts approximately one-fourth of stroke survivors and increases the likelihood of persistent disability.3-6 Prompt identification and treatment of PSD can improve affective symptoms and stroke related disability.7,8
Source: The American Journal of Geriatric Psychiatry - January 24, 2020 Category: Geriatrics Authors: Dora Kanellopoulos, Victoria Wilkins, Jimmy Avari, Lauren Oberlin, Lindsay Arader, Merete Chaplin, Samprit Banerjee, George S. Alexopoulos Tags: Regular Research Article Source Type: research

Dimensions of Poststroke Depression and Neuropsychological Deficits in Older Adults
Stroke is the leading cause of both serious and long-term disability and the fifth leading cause of death in the United States.1,2 Poststroke depression (PSD) afflicts approximately one-fourth of stroke survivors and increases the likelihood of persistent disability.3 –6 Prompt identification and treatment of PSD can improve affective symptoms and stroke related disability.7,8
Source: The American Journal of Geriatric Psychiatry - January 24, 2020 Category: Geriatrics Authors: Dora Kanellopoulos, Victoria Wilkins, Jimmy Avari, Lauren Oberlin, Lindsay Arader, Merete Chaplin, Samprit Banerjee, George S. Alexopoulos Tags: Regular Research Article Source Type: research

Intraoperative Ischemic Stroke in Elective Spine Surgery: A Retrospective Study of Incidence and Risk
Conclusion. . With the increase of spinal procedures, it is important to identify patients at risk for having an ischemic stroke and to optimize their comorbidities preoperatively. Patients with intraoperative ischemic stroke carry a higher risk for morbidity and mortality during the index hospitalization. Level of Evidence: 4
Source: Spine - January 8, 2020 Category: Orthopaedics Tags: CLINICAL CASE SERIES Source Type: research

Large Vessel Occlusion in the Acute Stroke Patient
Acute ischemic stroke is a major cause of death and disability in the United States. Historically, acute stroke patients were treated with intravenous (IV) thrombolysis. Patients with large vessel occlusions (LVOs) should be offered mechanical thrombectomy, with or without IV thrombolysis, in an extended window up to 24  hours of last known well. Both treatment options are the standard of care for a patient with an LVO. It is critical that the intensive care unit nurse understand new treatment indications for LVO strokes, and the priorities of nursing care with medical and endovascular intervention.
Source: Critical Care Nursing Clinics of North America - December 23, 2019 Category: Nursing Authors: Kiffon M. Keigher Source Type: research

Stroke impact symptoms are associated with sleep-related impairment
In the United States, the economic burden of stroke is more than $72 billion annually.1 Stroke is a leading cause of disability worldwide,2 and approximately 40% of stroke survivors have some degree of lingering functional impairment.3 Stroke survivors often experience stroke impact symptoms in such domains as motor function, cognition, communication, mood, activities of daily living, and social participation4,5 which limit their ability to return home or to work and improve their quality of life.
Source: Heart and Lung - December 11, 2019 Category: Intensive Care Authors: Eeeseung Byun, Ruth Kohen, Kyra J. Becker, Catherine J. Kirkness, Sandeep Khot, Pamela H. Mitchell Source Type: research

Health Tip: Stroke Warning Signs
-- Stroke is the fifth leading cause of death and a leading cause of disability in the United States, says the American Stroke Association. The association mentions these warning signs: Face drooping. Is the person ' s smile uneven or lopsided? Arm...
Source: Drugs.com - Daily MedNews - December 5, 2019 Category: General Medicine Source Type: news

Why acute ischemic stroke patients in the United States use or do not use emergency medical services transport? Findings of an inpatient survey
Patients with acute ischemic stroke (AIS) who use emergency medical services (EMS) receive quicker reperfusion treatment which, in turn, mitigates post-stroke disability. However, nationally only 59% use EMS. ...
Source: BMC Health Services Research - December 3, 2019 Category: General Medicine Authors: Sudha Xirasagar, Meng-han Tsai, Khosrow Heidari, James W. Hardin, Yuqi Wu, Robert Wronski, Dana Hurley, Edward C. Jauch and Souvik Sen Tags: Research article Source Type: research

The burden of health conditions across race and ethnicity for aging Americans: Disability-adjusted life years
The objective of this study was to determine the burden of 10 health conditions across race and ethnicity for a nationally-representative sample of aging Americans. Data from the 1998 to 2014 waves of the Health and Retirement Study, an ongoing longitudinal-panel study, were analyzed. Those aged over 50 years who identified as Black, Hispanic, or White were included. There were 5510 Blacks, 3423 Hispanics, and 21,168 Whites in the study. At each wave, participants reported if they had cancer, chronic obstructive pulmonary disease, congestive heart failure, diabetes, back pain, hypertension, a fractured hip, myocardial i...
Source: Medicine - November 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

‘Salty’ Concern: Tackling High Salt Consumption in China
Veena S. Kulkarni, Associate Professor, Department of Criminology, Sociology and Geography, Arkansas State University, USA; and Raghav Gaiha, (Hon.) Professorial Research Fellow, Global Development Institute, University of Manchester, England.By Veena S. Kulkarni and Raghav GaihaNEW DELHI, India and JONESBORO, US, Oct 7 2019 (IPS) China’s almost meteoric transition from a being a low income to a middle income country within a span of four decades is often perceived as a miracle analogous to the post Second World War Japanese economic development experience. China’s GDP rose from $200 current United States dollars (US$ ...
Source: IPS Inter Press Service - Health - October 7, 2019 Category: International Medicine & Public Health Authors: Veena Kulkarni and Raghav Gaiha Tags: Asia-Pacific Development & Aid Economy & Trade Food & Agriculture Food Sustainability Globalisation Headlines Health Labour TerraViva United Nations Barilla Center for Food and Nutrition Foundation (BCFN) Source Type: news

Understanding the Global Prevalence of Hypertension in Children and Adolescents
Hypertension is a major risk factor for the development of cardiovascular disease morbidity and mortality worldwide. Stroke, heart failure, myocardial infarction, and peripheral arterial disease are all outcomes associated with hypertension in adults. Hypertension is also considered to be a major cause of poorer disability-adjusted life-years. The prevalence of hypertension in adults has been debated in part because the definition of hypertension has changed over time. The association between blood pressure and cardiovascular disease is a continuous one, making the establishment of a cut point for hypertension difficult. H...
Source: JAMA Pediatrics - October 7, 2019 Category: Pediatrics Source Type: research