• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Stroke Literacy in Singapore: Data From a Survey of Public Housing Estate Residents.
Conclusion: In a sample of Singaporean adults residing in a public housing estate, we found evidence of poor stroke literacy, highlighting the need for comprehensive population-based education efforts. There is a role for opportunistic education among those at higher risk of stroke. PMID: 25341630 [PubMed - as supplied by publisher]
Source: Annals of the Academy of Medicine, Singapore - September 1, 2014 Category: Journals (General) Authors: Lim W, Chuang DF, Chue KM, Lee DZ, Leong NJ, Ng ZG, Peng K, Shen X, Tham YN, Wang K, De Silva DA Tags: Ann Acad Med Singapore Source Type: research

The Relationship Between Ambient Air Pollution and Acute Ischemic Stroke: A Time-Stratified Case-Crossover Study in a City-State With Seasonal Exposure to the Southeast Asian Haze Problem
ConclusionWe found a short-term elevated risk of ischemic stroke after exposure to air pollution. These findings have public health implications for stroke prevention and emergency health services delivery.
Source: Annals of Emergency Medicine - August 30, 2018 Category: Emergency Medicine Source Type: research

Wake-up Stroke and Onset-to-door Duration Delays: Potential Future Indications for Reperfusion Therapy.
Conclusion: The one- third proportion of wake-up stroke in this cohort and low prevalence of relative contraindications suggest this is a promising group for emerging thrombolysis indications. With the majority of patients presenting after 8 hours, widening of the therapeutic window with new potential reperfusion treatments would not appreciably increase treatment utilisation. This study reaffirms the urgent need for public education to improve stroke awareness in Singapore. PMID: 24557460 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 1, 2014 Category: Journals (General) Authors: Tan MSh, Ang ES, Ho SS, Ng SC, Talabucon L, Woon FP, De Silva DA Tags: Ann Acad Med Singapore Source Type: research

Public awareness of sepsis and stroke in singapore: a population-based survey.
Conclusion: Our findings reflect the differences in the public profile of sepsis versus stroke in Singapore. More concerted efforts involving healthcare professionals, medical societies, statutory boards, and the mass media are required to improve public awareness of these 2 conditions -especially sepsis. PMID: 23842767 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - June 1, 2013 Category: Journals (General) Authors: Phua J, Lim HF, Tay CK, Aung NW Tags: Ann Acad Med Singapore Source Type: research

Inactive bowel movement and stroke are associated with increased risks of mild cognitive impairment among community-living Singapore elderly.
Abstract Mild cognitive impairment (MCI), as a preclinical phase of dementia, provides an invaluable time window for intervention. Besides several proposed modifiable risk factors, the associations of MCI with dietary habits and bowel movement are not well clarified. We thus conducted a cross-sectional study of community-living Singapore elderly and focused on the relationship of clinically diagnosed MCI with dietary habits and bowel movement frequencies. The multiple logistic regression results showed that frequent (≥4 days per week) fruit consumption (P = 0.004), active (≥4 days per week) bowel movement with...
Source: Aging - September 8, 2020 Category: Biomedical Science Authors: Huang KY, Tang XY, Yang L, Zhang ZY, Ye KX, Shen QF, Wang X, Zhu XH, Huang XW, Lu GD, Feng L Tags: Aging (Albany NY) Source Type: research

Regional Differences in Early BP Management After Acute Ischemic Stroke in the ENCHANTED International Randomized Controlled Trials
Conclusion: Regional variations in early BP management in acute stroke translated into differences in early BP control parameters.
Source: Frontiers in Neurology - August 27, 2021 Category: Neurology Source Type: research

Periodontal Disease Is Associated With Increased Risk of Hypertension: A Cross-Sectional Study
Conclusion: Periodontal disease is significantly and positively correlated with increased risk of hypertension in Chinese population, and exact mechanisms of this association should be explored in future. Introduction Periodontal disease is a complex polymicrobial inflammation, including gingivitis and periodontitis. According to the 2015 Global Burden of Disease (GBD) study, the prevalence of severe chronic periodontitis in 2015 has reached 616 million (Kassebaum et al., 2017). In China, the periodontal disease standardized DALYs rate has risen from 24.7 in 1990 to 25.7 in 2013 according to the data from 2013 GBD ...
Source: Frontiers in Physiology - April 24, 2019 Category: Physiology Source Type: research

Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
CONCLUSION: Eight biased TCM constitutions were closely related to specific diseases, and could be used to guide individualized prevention and treatment. More rigorously designed studies are recommended to further verify the constitution-disease relationship. PMID: 32744037 [PubMed - in process]
Source: Journal of Traditional Chinese Medicine - July 31, 2020 Category: Complementary Medicine Authors: Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L Tags: J Tradit Chin Med Source Type: research

Age-Dependence of Flow Homeostasis in the Left Ventricle
Conclusions: In average, blood spends 1 to 3 beats inside the LV with very low shear stress rates. The apical region is the most prone to blood stasis, particularly in mid-aged adults. The washout of blood in the normal LV is age-dependent due to physiological changes in the degree of apical penetration of the filling waves. Introduction Cardioembolic stroke is a major source of mortality and disability worldwide and blood stasis one of its major determinants (Adams et al., 1986). Left ventricular (LV) function has evolved to maximize mechanical efficiency and ensure organ perfusion at a low cost of energy and fill...
Source: Frontiers in Physiology - April 25, 2019 Category: Physiology Source Type: research

Factors Associated with Chronic Kidney Disease and Their Clinical Utility in Primary Care Clinics in a Multi-Ethnic Southeast Asian Population
Conclusions: CKD prevalence in our Southeast Asian population is high and under-documented even in high-risk patients. Our findings highlight factors associated with CKD, and the predictive value of hypertension, diabetes, and advancing age as EHR-based screening targets for CKD. Our results also suggest that complementary educational efforts will be needed to increase physician detection and optimize the management of CKD, especially in high risk and marginalized groups across all clinics in Singapore, and possibly in the region.Nephron
Source: Nephron - December 15, 2017 Category: Urology & Nephrology Source Type: research

Preventable Cases of Oral Anticoagulant-Induced Bleeding: Data From the Spontaneous Reporting System
Conclusion: Our findings describe the most reported risk factors for preventability of oral anticoagulant-induced bleedings. These factors may be useful for targeting interventions to improve pharmacovigilance activities in our regional territory and to reduce the burden of medication errors and inappropriate prescription. Introduction Oral anticoagulant therapy is widely used for the prevention of stroke and systemic embolism in patients with atrial fibrillation, or for the prevention and treatment of deep vein thrombosis and pulmonary embolism (Raj et al., 1994; Monaco et al., 2017). Oral anticoagulants can be di...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Interaction between a haptoglobin genetic variant and coronary artery disease (CAD) risk factors on CAD severity in Singaporean Chinese population
ConclusionHP genetic variant is not associated with CAD severity and mortality in the general population. However, hypertensive individuals with the rs217181 T allele associated with higher Hp levels had more severe CAD while non ‐hypertensive individuals with the same allele had lower risk for mortality in the Chinese population.
Source: Molecular Genetics & Genomic Medicine - August 12, 2020 Category: Genetics & Stem Cells Authors: Xuling Chang, Rajkumar Dorajoo, Yi Han, Ling Wang, Jianjun Liu, Chiea ‐Chuen Khor, Adrian F. Low, Mark Yan‐Yee Chan, Jian‐Min Yuan, Woon‐Puay Koh, Yechiel Friedlander, Chew‐Kiat Heng Tags: ORIGINAL ARTICLE Source Type: research

Cardiometabolic and Vascular Disease Factors and Mild Cognitive Impairment and Dementia
Conclusion: Older adults with higher burden of CMVD, driven especially by diabetes, are likely to increase the risk of prevalent and incident MCI and dementia.Gerontology
Source: Gerontology - January 26, 2022 Category: Geriatrics Source Type: research

Coarctation of the aorta: nonsurgical treatment using stent implantation.
CONCLUSION: This is the first reported series in Singapore on the nonsurgical treatment of CoAs in adult patients using stents during interventional cardiac catheterisation. This less invasive procedure may lead to a new paradigm shift with regard to the treatment of CoA. PMID: 25017404 [PubMed - in process]
Source: Singapore Medical Journal - June 1, 2014 Category: Journals (General) Authors: Ang HL, Lim CW, Hia C, Yip J, Quek SC Tags: Singapore Med J Source Type: research

Epidemiology of a Rare Event
Retinal emboli are rare, with a prevalence in most of the relatively few studies on the subject, to my knowledge, of approximately 1 in 100 adults and an even smaller annual incidence. The study by Cheung et al in the present issue ofJAMA Ophthalmology involves the multiethnic population of Singapore and found that retinal emboli were present in only 88 of 9978 individuals who had retinal photographs (0.9%). This randomly selected sample of adults aged 40 to 80 years comprised, in almost equal numbers, of members of the 3 major ethnic groups residing in Singapore: Chinese, Malay, and Indian. Cheung et al provided data rele...
Source: JAMA Ophthalmology - October 1, 2017 Category: Opthalmology Source Type: research

Pages: 1  2