Periodontal Disease Is Associated With Increased Risk of Hypertension: A Cross-Sectional Study

Conclusion: Periodontal disease is significantly and positively correlated with increased risk of hypertension in Chinese population, and exact mechanisms of this association should be explored in future. Introduction Periodontal disease is a complex polymicrobial inflammation, including gingivitis and periodontitis. According to the 2015 Global Burden of Disease (GBD) study, the prevalence of severe chronic periodontitis in 2015 has reached 616 million (Kassebaum et al., 2017). In China, the periodontal disease standardized DALYs rate has risen from 24.7 in 1990 to 25.7 in 2013 according to the data from 2013 GBD study (Zhang et al., 2017). Periodontal disease is considered as a potential risk factor for various systematic diseases, and previously published systematic reviews and meta-analyses have indicated that this disease could increase the risk of atherosclerotic complications, such as cardiovascular disease (Mustapha et al., 2007; Zeng et al., 2017), arterial stiffness (Schmitt et al., 2015), carotid intima-media thickness (Orlandi et al., 2014), carotid atherosclerosis (Zeng et al., 2016a), stroke (Lafon et al., 2014), coronary heart disease (Leng et al., 2015), erectile dysfunction (Cheraghi and Doosti-Irani, 2017), and hypertension (Martin-Cabezas et al., 2016). Hypertension is a well-known risk factor for atherosclerotic vascular diseases, with prevalence among adults of 34% in the United States (Roger et al., 2012) and 30–45% in European countries (M...
Source: Frontiers in Physiology - Category: Physiology Source Type: research

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