Age-Dependence of Flow Homeostasis in the Left Ventricle

Age-Dependence of Flow Homeostasis in the Left Ventricle Yolanda Benito1, Pablo Martinez-Legazpi1*, Lorenzo Rossini2, Candelas Pérez del Villar1, Raquel Yotti1, Yolanda Martín Peinador3, Daniel Rodríguez-Pérez4, M. Mar Desco4, Constancio Medrano1, Jose Carlos Antoranz4, Francisco Fernández-Avilés1, Juan C. del Álamo2,5 and Javier Bermejo1 1Department of Cardiology, Hospital General Universitario Gregorio Marañón, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón and CIBERCV, Madrid, Spain 2Department of Mechanical and Aerospace Engineering, University of California, San Diego, La Jolla, CA, United States 3Centro de Salud Goya, Dirección Asistencial Centro, Atención Primaria de Madrid, Madrid, Spain 4Department of Mathematical Physics and Fluids, Facultad de Ciencias, Universidad Nacional de Educación a Distancia, Madrid, Spain 5Institute for Engineering in Medicine, University of California, San Diego, La Jolla, CA, United States Background: Intracardiac flow homeostasis requires avoiding blood stasis and platelet activation during its transit through the cardiac chambers. However, the foundations of intraventricular blood washout and its exposure to shear stresses have been poorly addressed. We aimed to characterize and quantify these features in a wide population of healthy subjects and assess the ...
Source: Frontiers in Physiology - Category: Physiology Source Type: research

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Journal Name: Journal of Perinatal Medicine Issue: Ahead of print
Source: Journal of Perinatal Medicine - Category: Perinatology & Neonatology Source Type: research
Leptomeningeal anastomoses or pial collateral vessels play a critical role in cerebral blood flow (CBF) restoration following ischemic stroke. The magnitude of this adaptive response is postulated to be controlled by the endothelium, although the underlying molecular mechanisms remain under investigation. Here we demonstrated that endothelial genetic deletion, using EphA4fl/fl/Tie2-Cre and EphA4fl/fl/VeCahderin-CreERT2 mice and vessel painting strategies, implicated EphA4 receptor tyrosine kinase as a major suppressor of pial collateral remodeling, CBF, and functional recovery following permanent middle cerebral artery occ...
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Source: Journal of Alloys and Compounds - Category: Chemistry Source Type: research
Publication date: 15 May 2020Source: Journal of Alloys and Compounds, Volume 823Author(s): Stephan Laube, Hans Chen, Alexander Kauffmann, Steven Schellert, Franz Müller, Bronislava Gorr, Julian Müller, Benjamin Butz, Hans-Juergen Christ, Martin HeilmaierAbstractRefractory high entropy alloys (RHEAs) from the Mo–Cr–Ti–Al system exhibit promising strength at elevated temperatures. However, at room temperature they possess a B2-ordered crystal structure and, therefore, exhibit reduced ductility. Guided by thermodynamic calculations, the Al concentration was systematically reduced in MoCrTi-xAl (x&n...
Source: Journal of Alloys and Compounds - Category: Chemistry Source Type: research
New J. Chem., 2020, Accepted Manuscript DOI: 10.1039/C9NJ05830C, PaperLinsen Huang, Liangxing Zhang, Deyu Bao, Xiaoqing Jiang, Junhua Li, Xiaosong Sun The present study focuses on the synthesis and the characterization of ternary photo-catalyst rGO-Sb4O5Cl2-Sb2S3. A series of rGO-Sb4O5Cl2-Sb2S3 samples were synthesized by the ultrasonic assistant chemical co-precipitation method, and the... The content of this RSS Feed (c) The Royal Society of Chemistry
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Letter of Intent Deadline Date: February 21, 2020 Program Guidelines: NSF 20-530NSF solicits proposals to manage the operations and maintenance of the National Ecological Observatory Network (NEON), an NSF-funded major facility project.  NEON comprises terrestrial, aquatic, atmospheric, and remote sensing measurement infrastructure and cyberinfrastructure that deliver standardized, calibrated data to the scientific community through a single, openly accessible data portal.  NEON infrastructure is geographically distributed across the United States, ...More at
Source: NSF Upcoming Due Dates - Category: Science Source Type: funding
Recent years have witnessed the proliferation of victim-focused positions inside and outside the criminal justice system, yet little is known about the occupational characteristics and organizational context of this field in the United States. In this arti...
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Authors: Monte A, Nardello F, Pavei G, Moro S, Festa L, Tarperi C, Schena F, Zamparo P Abstract BACKGROUND: The aim of this study was to determine the influence of spring mass model characteristics (e.g. stiffness) and Achilles tendon proprieties in determining the energy cost of running in half marathon runners. METHODS: Achilles tendon characteristics (i.e. cross sectional area -ATCSA- and resting length - ATL-) were measured on 32 males by means of an ultrasound apparatus the day before a half marathon race. After these measurements the energy cost of running (C) was determined while the subjects run on a tr...
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Review of English-language articles published from PubMed (MEDLINE) and Google Scholar between January 1, 1985, and January 1, 2019.
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Multicenter retrospective analysis of patients entered in the prospective, randomized International Carotid Stenting Study between May 2001 and October 2008.
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