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Stroke Survivors Benefit From Regular, Brisk Outdoor Walks
A new study finds that taking regular brisk walks outdoors can help people recovering from a stroke to improve their physical fitness, enjoy a better quality of life, and increase their mobility. The researchers, from the University of the West Indies in Jamaica, write about their findings in the 6 March online issue of the journal Stroke. After experiencing a stroke, many survivors have less energy and walk less because of fear of falling. They also tend to reduce meaningful activity like going to the shops, visiting family and friends, or going to church...
Source: Health News from Medical News Today - March 8, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Walking Program Improves Stroke Survivors' Lives
Regular, brisk walking after having a stroke could help boost your physical fitness, mobility and quality of life, according to research in the American Heart Association journal Stroke. "Walking is a great way to get active after a stroke," said Carron Gordon, Ph.D., lead author of the study and a lecturer in the physical therapy department at University of the West Indies in Jamaica. "It's familiar, inexpensive, and it's something people could very easily get into...
Source: Health News from Medical News Today - March 10, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Jamaican Susumber Berry Poisoning Mimicking Acute Stroke
Conclusions: SB toxicity can cause neurological symptoms that mimic an acute stroke typically with a posterior circulation symptom complex. Altered SB toxins (from post-harvest stressors or temperature changes) might stimulate muscarinic/nicotinic cholinergic receptors or inhibit acetylcholinesterase, causing gastrointestinal, neurological, and autonomic symptoms. In cases of multiple patients presenting simultaneously to the ED with stroke-like symptoms or when stroke-like symptoms fail to localize, a toxicological etiology (such as SB toxicity) should be considered.Cerebrovasc Dis
Source: Cerebrovascular Diseases - October 25, 2022 Category: Neurology Source Type: research

Effects of a Week-Long Intense Rehabilitation Camp on Walking Outcomes of Stroke Individuals in Jamaica
The purpose of this retrospective analysis was to investigate the effects of a week-long, intense and structured rehabilitation camp on gait speed in patients with stroke. We further investigated if baseline walking performance, categorized by pre-intervention gait speed (household ambulators (0.8 m/s)) determined the amount of improvement in gait speed post-intervention.
Source: Archives of Physical Medicine and Rehabilitation - September 24, 2017 Category: Rehabilitation Authors: Andrew Nauss, Rachel Jordon, Gabe Rocco, Brooke Riley, Bethany Wolf, Rochelle Mendonca, Michelle Johnson, Shailesh Kantak Source Type: research

A Case of Foreign Accent Syndrome
Conclusion: Clinicians should be aware that some stroke patients present with various atypical symptoms, and should suspect stroke in any patient with acute-onset neurological symptoms, including speech change.
Source: The Journal of Emergency Medicine - March 18, 2013 Category: Emergency Medicine Authors: Ashley X. Tran, Lisa D. Mills Tags: Clinical Communications: Adults Source Type: research

Prevention of conversion to abnormal tcd with hydroxyurea in sickle cell anemia: A phase III international randomized clinical trial
This article is protected by copyright. All rights reserved.
Source: American Journal of Hematology - September 28, 2015 Category: Hematology Authors: Jane S. Hankins, M. Beth McCarville, Angela Rankine‐Mullings, Marvin E. Reid, Clarisse L.C. Lobo, Patricia G. Moura, Susanna Ali, Deanne Soares, Karen Aldred, Dennis W. Jay, Banu Aygun, John Bennett, Guolian Kang, Jonathan C. Goldsmith, Matthew P. Smelt Tags: Research Article Source Type: research

Prevention of conversion to abnormal transcranial Doppler with hydroxyurea in sickle cell anemia: A Phase III international randomized clinical trial
Children with sickle cell anemia (SCA) and conditional transcranial Doppler (TCD) ultrasound velocities (170–199 cm/sec) may develop stroke. However, with limited available clinical data, the current standard of care for conditional TCD velocities is observation. The efficacy of hydroxyurea in preventing conversion from conditional to abnormal TCD (≥200 cm/sec), which confers a higher stroke risk, has not been studied prospectively in a randomized trial. Sparing Conversion to Abnormal TCD Elevation (SCATE #NCT01531387) was a National Heart, Lung, and Blood Institute‐funded Phase III multicenter international clinical...
Source: American Journal of Hematology - November 17, 2015 Category: Hematology Authors: Jane S. Hankins, Mary Beth McCarville, Angela Rankine‐Mullings, Marvin E. Reid, Clarisse L.C. Lobo, Patricia G. Moura, Susanna Ali, Deanne P. Soares, Karen Aldred, Dennis W. Jay, Banu Aygun, John Bennett, Guolian Kang, Jonathan C. Goldsmith, Matthew P. Tags: Research Article Source Type: research

Transcranial Doppler velocity among Jamaican children with sickle cell anaemia: determining the significance of haematological values and nutrition
This study investigated the association of nutritional and haematological variables with maximum time‐averaged mean velocity (TAMV) measured by transcranial Doppler (TCD) velocity and the agreement of classification between two protocols. TCD categories included: normal (<170 cm/s), conditional (170–199 cm/s) and abnormal (≥200 cm/s) based on TAMV in distal internal carotid artery (dICA), middle cerebral artery (MCA), internal carotid bifurcation, anterior and posterior cerebral arteries. Of 358 children with sickle cell anaemia (SCA) examined, the mean age (±standard deviation) was 7·4 ± 2·7 years; 13·...
Source: British Journal of Haematology - March 1, 2018 Category: Hematology Authors: Angela E. Rankine ‐Mullings, Nadine Morrison‐Levy, Deanne Soares, Karen Aldred, Lesley King, Susanna Ali, Jennifer M. Knight‐Madden, Margaret Wisdom‐Phipps, Robert J. Adams, Russell E. Ware, Marvin Reid Tags: Research Paper Source Type: research

Evolving locally appropriate models of care for indian sickle cell disease.
Abstract The sickle cell gene in India represents a separate occurrence of the HbS mutations from those in Africa. Sickle cell disease in India occurs against different genetic and environmental backgrounds from those seen in African patients and there is evidence of clinical differences between the populations. Knowledge of the clinical features of African disease was drawn from the Jamaican Cohort Study, based on prospective follow up of all cases of sickle cell disease detected by the screening of 100,000 consecutive newborns in Kingston, Jamaica, and supplemented by observations from the Cooperative Study of S...
Source: Indian J Med Res - March 31, 2016 Category: Research Authors: Serjeant GR Tags: Indian J Med Res Source Type: research

Latin American, Caribbean health systems need more investment as populations age
The health systems of six Latin American and Caribbean countries have made substantial progress toward universal coverage — providing free or subsidized healthcare to the majority of their populations — but continue to face challenges managing more complex health needs such as those related to cardiovascular disease, cancer, stroke and depression, a new study from the UCLA Fielding School of Public Health and the Inter-American Development Bank finds. Though the health systems in Brazil, Colombia, El Salvador, Jamaica, Mexico and Panama have considerable strengths, citizens still reported gaps in the way primary care i...
Source: UCLA Newsroom: Health Sciences - August 8, 2016 Category: Universities & Medical Training Source Type: news

The Causes of Maternal Mortality are Changing and Preventable.
This article is protected by copyright. All rights reserved. PMID: 29673041 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 19, 2018 Category: OBGYN Authors: Stokes MJ, Wilkinson JP Tags: BJOG Source Type: research

Hemolytic, Vaso-Occlusive and Renal Complications of SCD: Report from the Central Missouri Cohort
ConclusionsThis is the first report describing prevalence of SCD-related complications in the MU-SCD Cohort. We identified this population to have an increasing frequency of hemolytic complications and sickle cell nephropathy with advancing age. Onset of persistent proteinuria occurred in the second decade of life, followed by renal insufficiency or end stage renal disease in subsequent decades. As previously demonstrated in the Cooperative Study of Sickle Cell Disease and the Jamaican SCD Cohort study, renal insufficiency was a significant risk factor for early mortality. Further studies are required for identification of...
Source: Blood - November 21, 2018 Category: Hematology Authors: Nolan, L. W., Yoshida, Y., Coberly, E., Sathi, B. K. Tags: 114. Hemoglobinopathies, Excluding Thalassemia-Clinical: Poster I Source Type: research

Neuroimmunology of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis
Conclusion Recent advances in research on HTLV-1 provide better understanding of the molecular pathogenesis and mechanisms of HAM/TSP, and several clinical trials of novel therapies for patients with HAM/TSP have been initiated. However, long-term improvement of motor disability and quality of life still have not been achieved in HAM/TSP patients, and the clinical management remains challenging. Given that HAM/TSP is characterized by activated T-cells in both the periphery and CNS, studies in HAM/TSP will be highly informative for clarifying the pathogenesis of other neuroinflammatory disorders such as multiple sclerosis....
Source: Frontiers in Microbiology - April 23, 2019 Category: Microbiology Source Type: research

Sickle Cell Disease and Pain: Is it all Vaso-occlusive Crises?
Discussion: CP and NP should be assessed during routine care of sickle cell pain so that targeted therapies can be applied.
Source: The Clinical Journal of Pain - July 15, 2021 Category: Anesthesiology Tags: Original Articles Source Type: research