Pain-related Self-efficacy Among People With Back Pain: A Systematic Review of Assessment Tools
Conclusions: Further research should focus on assessing validity and interpretability of these questionnaires, especially in pain-related target groups. Researchers should select questionnaires that are most appropriate for their study aims and the back pain population and contribute to further validation of these scales to best predict future behavior and develop intervention programs. This systematic review aids selection of pain-related assessment tools in back pain both in research and practice. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 11, 2020 Category: Anesthesiology Tags: Review Article Source Type: research

Utilization of Health Care Resources by Long-term Care Residents as a Function of Pain Status
Discussion: To our knowledge, this is the first large-scale project to examine the utilization of health care resources as a function of pain status among LTC facility residents. Improved pain management in LTC facilities could lead to reduced health care use. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 11, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Changes in Pain and Psychosocial Functioning and Transition to Chronic Pain in Pediatric Sickle Cell Disease: A Cohort Follow-up Study
This study aimed to: (1) examine changes in pain, psychosocial functioning, and health care utilization among children and adolescents with sickle cell disease (SCD) over a 2-year period and (2) identify baseline biopsychosocial variables associated with the development and maintenance of chronic SCD pain at follow-up. Materials and Methods: Forty-two youth (8 to 18 y old) with SCD completed a battery of self-report measures at baseline and 2-year follow-up. Analgesic, Anesthetic, and Addiction Clinical Trial Translational Innovations Opportunities and Networks and American Pain Society Pain Taxonomy (AAPT) diagn...
Source: The Clinical Journal of Pain - May 11, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Effect on Opioids Requirement of Early Administration of Intranasal Ketamine for Acute Traumatic Pain
Objectives: To evaluate the efficacy and safety of early administration of low-dose intranasal ketamine on reducing the need for opioid and nonopioid analgesic agents in emergency department (ED) patients with acute moderate to severe acute limbs’ trauma pain. Patients and Methods: This is a double-blind, randomized, prospective, controlled study conducted in the ED. The included patients were randomly assigned to intranasal pulverization of ketamine or placebo. Protocol treatment was given at the triage. The primary outcome is the need for opioids during ED stay. Secondary outcome included the requirement of no...
Source: The Clinical Journal of Pain - May 11, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Neurological Complication Rates of Epidural Injections and Selective Nerve Blocks: A Comparison of Steroid Use Patterns
Discussion: At the cervicothoracic level, the incidence rate of neurological complications with particulate steroid injections was higher than that with nonparticulate steroid injections. Injections with nonparticulate steroids and without steroids were equally safe. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 11, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Quality of Life in Youth With Chronic Pain: An Examination of Youth and Parent Resilience and Risk Factors
Discussion: The results are discussed in the context of the resilience-risk framework and current understandings of the role of parental factors for pediatric chronic pain. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 11, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Contribution of COMT and BDNF Genotype and Expression to the Risk of Transition From Acute to Chronic Low Back Pain
Discussion: CLBP was characterized by higher reported pain burden and augmented hypersensitivity at LBP onset. COMT expression and genotype were associated with acute pain burden and likelihood of transition to CLBP. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 11, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Sex Bias and Genotype Influence on Opioid Safety Profile in Chronic Low Back Pain
Conclusions: Sex bias affects female patients resulting in a CLBP diagnostic delay and a different analgesic safety profile. Moreover, the individual’s genetic background might be useful to predict certain AEs in opioid-naive patients under an opioid titration procedure. Addressing sex in necessary to resolve inequalities in health care access. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - May 11, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

The Influence of a Positive Empathetic Interaction on Conditioned Pain Modulation and Manipulation-induced Analgesia in People With Lateral Epicondylalgia
Objective: Conditioned pain modulation (CPM) and manipulation-induced analgesia (MIA) are 2 forms of endogenous analgesia. Many forms of analgesia can be influenced by the nature of the patient-clinician interaction. The aim of this study was to evaluate the influence of an empathetic and supportive interaction on CPM and MIA in people with lateral epicondylalgia (LE). Material and Methods: In a double-blind, randomized, controlled trial, 68 participants with LE were assigned to 2 groups: the empathetic and neutral interaction groups. The interactions were carried out by a trained, professional role-play actor, playin...
Source: The Clinical Journal of Pain - May 11, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Efficacy and Safety of Tapentadol Immediate Release for Acute Pain: A Systematic Review and Meta-Analysis
Objective: Tapentadol (TAP) immediate release (IR) is a newer opioid option for acute pain. The aim of this systematic review was to examine the efficacy and safety of TAP IR compared with other opioids for acute pain. Methods: A systematic literature search as conducted using the Cochrane Library, Embase, International Pharmaceutical Abstracts, MEDLINE, PubMed, and Web of Science. The search included all randomized controlled trials and observational studies examining TAP IR versus other orally administered IR opioids for acute pain. The protocol for this study was registered on PROSPERO (CRD42018110267). Results: ...
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Review Articles Source Type: research

A Systematic Review of Clinical Practice Guidelines for Acute Procedural Pain on Neonates
Discussion: The results of this review show that there is a need to improve the methodological quality of guidelines for procedural pain in newborns. The set of recommendations for procedural pain prevention needs to involve not only pharmacological and nonpharmacological pain treatment but also parents and interprofessional collaboration. It is also essential to take into account facilitators, barriers, and the context to improve pain management. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Review Articles Source Type: research

Association Between Inflammatory Biomarkers and Nonspecific Low Back Pain: A Systematic Review
Discussion: Our findings support the notion of a positive association between inflammatory biomarkers and nonspecific LBP, specifically for CRP, TNFs, and IL-6. Although further high quality longitudinal studies are needed to confirm these findings and evaluate the magnitude of these associations, our findings suggest a role of inflammation in the pathogenesis of nonspecific LBP. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Review Articles Source Type: research

Social Factors, Disability, and Depressive Symptoms in Adults With Chronic Pain
Discussion: The study provides important new findings regarding the associations between social factors and physical and psychological functioning of individuals with chronic pain, supporting biopsychosocial models. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Variables Associated With Administration of Nurse-initiated Analgesia in Pediatric Triage
We examined variables that influence the provision of analgesia in a pediatric emergency department that uses TNIA. Methods: A 4-year retrospective cohort study of all children with triage pain scores ≥1 was conducted. Data on demographics and patients’ and nurses’ characteristics were collected. Logistic regression analyses were used to examine the effect of multiple variables on the provision of any analgesia and opioid analgesia. Results: Overall, 28,746 children had triage pain scores ≥1; 14,443 (50.2%) patients received analgesia of any type and 1888 (6.6%) received opioid analgesia. Mean time ...
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Attitudes Towards and Management of Opioid-induced Hyperalgesia: A Survey of Chronic Pain Practitioners
Discussion: Most clinicians agreed that OIH is a complication of opioid therapy, but were divided regarding the prevalence of OIH, etiological factors, and optimal management. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery
Conclusion: The current study demonstrated no analgesic effects of postoperative chlorzoxazone administration compared with placebo on acute or chronic postoperative pain 12 months following TKR and THR. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Validating Invalidation: Examining the Construct Validity of the Illness Invalidation Inventory Among Individuals With Chronic Low Back Pain
Discussion: The 2-factor model of the 3*I “family members” subscale identified in the current study reflects previous findings and extends the psychometric validity of the 3*I to a US multiethnic sample of individuals with CLBP. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

The Relationship Between Clinical and Quantitative Measures of Pain Sensitization in Knee Osteoarthritis
This study examines the relationship between quantitative sensory testing (QST) and clinical measures of pain sensitization in people with knee OA. Methods: A secondary analysis of data from 134 participants with knee OA was performed. Clinical measures included: manual tender point count (MTPC), the Central Sensitization Inventory (CSI) to capture centrally mediated comorbidities, number of painful sites on a body chart, and neuropathic pain-like symptoms assessed using the modified PainDetect Questionnaire. Relationships between clinical measures and QST measures of pressure pain thresholds (PPTs), temporal summation,...
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Assessment of Somatosensory and Psychosocial Function of Patients With Trigeminal Nerve Damage
Objective: The present study assessed somatosensory changes related to trigeminal nerve damage using extensive evaluation tools and assessed the effect of such damage on the patients’ psychosocial status and quality of life compared with healthy participants. Methods: In 37 patients with intraorally or extraorally presenting trigeminal nerve damage diagnosed as painful or nonpainful posttraumatic trigeminal neuropathy, psychophysical tests like quantitative sensory testing (QST) and qualitative sensory testing and the electrophysiological “nociceptive-specific” blink reflex were performed. The patien...
Source: The Clinical Journal of Pain - April 7, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Adherence to Consolidated Standards of Reporting Trials (CONSORT) Guidelines for Reporting Safety Outcomes in Trials of Medical Cannabis and Cannabis-based Medicines for Chronic Noncancer Pain: A Systematic Review
Discussion: Better harms assessment and reporting are needed in chronic pain cannabinoid trials. Improvements may be achieved through: expanded education/knowledge translation increased research regulation by ethics boards, funding agencies and journals, and greater emphasis on safety assessment and reporting throughout research training. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Review Article Source Type: research

Factors Associated With Minimum Effective Volume of Lidocaine 1.5% for Sciatic Nerve Blocks
The objectives of this study were to investigate the correlations between the minimum effective volume (MEV) of lidocaine 1.5% for an ultrasound-guided popliteal sciatic nerve block and individual factors including the cross-sectional nerve area, sex, age, body mass index, and the depth of the sciatic nerve and to evaluate the safety of combined femoral and sciatic nerve blocks by monitoring the plasma concentration of local anesthetics. Methods: Forty patients received combined single-shot femoral and continuous sciatic nerve blocks. The femoral nerve block was performed with an in-plane technique and 15 mL of l...
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Targeting Occipital Headache Pain: Preliminary Data Supporting an Alternative Approach to Occipital Nerve Block
This study evaluated the efficacy and validity of an alternative, single skin insertion, paresthesia-based approach to block both the greater and lesser occipital nerve. Materials and Methods: Patients with a clinical diagnosis of occipital headache were included in this study. External landmarks of the cervical spinous process and ipsilateral tragus were used to predict the location of the OA pulse at the superior nuchal line. Alternative ONB technique was used to block both the greater and lesser occipital nerves using single skin insertion and paresthesia confirmation. Demographic data, preprocedure, and postprocedur...
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Development of a Measure of Nociception for Patients With Severe Brain Injury
Discussion: The results provide evidence that the Brain Injury Nociception Assessment Measure (BINAM) is reliable and feasible to administer. It can assess the intensity of nociception largely independent of the level of consciousness. Further research is warranted on the impact of BINAM use on the care of patients with severe traumatic brain injury. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Clinical Scenarios for Which Cervical Mobilization and Manipulation Are Considered by an Expert Panel to Be Appropriate (and Inappropriate) for Patients With Chronic Neck Pain
Conclusions: Clinical guidelines for CNP should include information on the clinical scenarios for which cervical mobilization and manipulation were found inappropriate, including those with red flags, and others involving major neurological findings if previous manual therapy was unfavorable. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Efficacy of Nalbuphine as an Adjuvant to Ropivacaine in Ultrasound-guided Supraclavicular Brachial Block: A Prospective Randomized Controlled Study
Conclusions: Nalbuphine is an effective adjuvant to 0.5% ropivacaine in ultrasound-guided supraclavicular BPB. The dosage of 10 mg improves the quality of the anesthesia with less incidence of side effects. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Electromyographic Comparison of the Efficacy of Ultrasound-guided Suprainguinal and Infrainguinal Fascia Iliaca Compartment Block for Blockade of the Obturator Nerve in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial
Conclusions: Suprainguinal FICB significantly increased the incidence of successful obturator nerve block and significantly decreased fentanyl consumption 24 hours after TKA compared with infrainguinal FICB. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

The Complex Interplay of Pain, Depression, and Anxiety Symptoms in Patients With Chronic Pain: A Network Approach
This study aimed to analyze the associations among depressive and anxiety and pain symptoms in patients diagnosed with chronic pain. Materials and Methods: Four hundred fifty-four inpatients who were consecutively admitted in a multimodal 3-week treatment in a tertiary, psychosomatic university clinic completed 25 items from the Brief Pain Inventory and the Hospital Anxiety and Depression Scale at baseline and after treatment termination. Associations among symptoms were explored by network analyses using the graphical least absolute shrinkage and selection operator to estimate their partial correlations, whereas Extend...
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

The Interplay of Parent and Child Coping Responses in Understanding Child Functioning in the Context of Living With a Parent With or Without Chronic Pain
Discussion: The current findings demonstrated that child functioning was associated with maternal and child pain catastrophizing, but only in children of mothers without CP. No evidence was found in support of maternal pain coping responses as vulnerability or protective factors in the context of parental CP. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Serum Inflammatory Markers in Patients With Knee Osteoarthritis: A Proteomic Approach
This study aimed to assess serum levels of 92 markers involved in inflammatory pathways in patients with knee osteoarthritis (KOA) and evaluate their possible associations with the clinical pain intensity. Materials and Methods: Serum samples were collected from 127 KOA patients and 39 healthy participants with no knee pain. Each serum sample was analyzed for 92 inflammatory markers using the Proximity Extension Array (PEA) technology. Clinical pain intensity was assessed using a Visual Analog Scale, and patients completed the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire. Results: Fifteen markers...
Source: The Clinical Journal of Pain - March 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Further Examination of the Pain Stages of Change Questionnaires Among Chronic Low Back Pain Patients: Long-Term Predictive Validity of Pretreatment and Posttreatment Change Scores and Stability of Posttreatment Scores
No abstract available (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Letter to the Editor Source Type: research

Enhanced Recovery After Surgery (ERAS): A Perspective Review of Postoperative Pain Management Under ERAS Pathways and Its Role on Opioid Crisis in the United States
The objective of this study was to review the current scientific evidence on the role of Enhanced Recovery After Surgery (ERAS) implementations in reducing postoperative opioid consumption and their potential association with the risk reduction for long-term opioid use, physical opioid dependency, and opioid addiction. Methods: A literature search was conducted using the following medical subject heading keywords: “postoperative pain,” “postoperative pain management,” “multimodal analgesia,” “ERAS,” “Enhanced Recovery,” “opioid-free analgesia,” or &...
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Review Article Source Type: research

Cosyntropin for the Treatment of Refractory Postdural Puncture Headache in Pediatric Patients: A Retrospective Review
This study suggests that while further research is warranted, cosyntropin is a potential alternative to epidural blood patch for pediatric patients with postdural puncture headache who fail conservative management. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Factors Related to Agreement Between Child and Caregiver Report of Child Functioning With Chronic Pain: PROMIS Pediatric and Parent Proxy Report
Discussion: Findings are discussed within the interpersonal context of pain and indicate the relevance of both child and caregiver perspectives to personalize chronic pain assessment and treatment. Findings can be used by clinicians and researchers to guide whether and how to integrate multi-informant reports about child chronic pain functioning. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

A Mediational Analysis of Stress, Inflammation, Sleep, and Pain in Acute Musculoskeletal Trauma
In this study, we test the hypotheses that pretrauma life stress influences posttrauma pain severity, and 2 potential mediating pathways, 1 biological (C-reactive protein, CRP) and 1 contextual (sleep quality). Materials and Methods: Data collected from participants within 3 weeks of a noncatastrophic musculoskeletal trauma were used in this observational cross-sectional mediation analysis. The primary outcome was pain severity as measured using the Brief Pain Inventory. Predictors were posttrauma CRP assayed from plasma, sleep interference measured by the Brief Pain Inventory, and a study-specific “General Life S...
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Effects of Tonic Spinal Cord Stimulation on External Mechanical and Thermal Stimuli Perception Using Quantitative Sensory Testing: A Multicenter Stimulation ON-OFF Study on Chronic Pain Patients
Objectives: Tonic spinal cord stimulation (SCS) is currently used to treat neuropathic pain. With this type of stimulation, an implantable pulse generator generates electrical paresthesias in the affected area through 1 or more epidural leads. The goal of this study was to evaluate the impact of tonic SCS on the sensory perception of chronic pain patients using quantitative sensory testing (QST). Materials and Methods: Forty-eight patients (mean age: 57 y) with chronic leg pain due to failed back surgery syndrome or complex regional pain syndrome treated with SCS were recruited from 3 research centers. Test pro...
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

The Impact of Spatial Distribution of Pain on Long-Term Trajectories for Chronic Pain Outcomes After Intensive Interdisciplinary Pain Treatment
Discussion: Overall, spatial distribution of pain, coping efficacy, and pain intensity played an important role in patients’ response to treatment. Better understanding of these variables could improve treatment response, particularly for the most severely disabled chronic pain patients. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Embodied Pain: There is a Need to Reflect Interactions Between Cognitions, Behavior, and Neuromuscular Activity in Chronic Pain
No abstract available (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Special Topic Series: Approach to Physical Activity in Pain: From Theory to the Lab, From Clinic to the Patient Source Type: research

Psychological Subgrouping to Assess the Risk for the Development or Maintenance of Chronic Musculoskeletal Pain: Is This the Way Forward?
Conclusions: We conclude that it is possible to reliably subgroup patients with musculoskeletal problems. Likewise, treatments that address the risk factors in the screening procedure may enhance outcomes compared with treatment as usual. More work is needed, however, to better understand the mechanism, so that assessment methods can be improved, and treatment specific to subgroups can be developed and evaluated. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Special Topic Series: Approach to Physical Activity in Pain: From Theory to the Lab, From Clinic to the Patient Source Type: research

Overactivity in Chronic Pain, the Role of Pain-related Endurance and Neuromuscular Activity: An Interdisciplinary, Narrative Review
Discussion: This narrative review brings together different research lines on overactivity, pain-related endurance, and supposed neuromuscular consequences. Clinicians should distinguish between patients who rest and escape from pain at low levels of pain, but who have high levels of fear of pain and those who predominantly persist in activities despite severely increasing pain until a break will be enforced by intolerable pain levels. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Special Topic Series: Approach to Physical Activity in Pain: From Theory to the Lab, From Clinic to the Patient Source Type: research

Endogenous Modulation of Pain: The Role of Exercise, Stress, and Cognitions in Humans
Conclusion: On the basis of current knowledge on the role of exercise, stress, and cognitive pain control strategies on the modulation of pain, implications for treatment will be discussed. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Special Topic Series: Approach to Physical Activity in Pain: From Theory to the Lab, From Clinic to the Patient Source Type: research

Pain Unstuck: The Role of Action and Motivation
Conclusions: In taking a wide view of pain and action, we expose the nuances within drive to goal behaviour in the presence of pain. This has implications for the clinic, specifically in relation to assessing the multifactorial influences that shape action in pain. But it also seeks to go further, considering the broader environment in which we make decisions and the influence that other professionals, outside of typical healthcare roles, may play a part in the maintenance and resolution of pain. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - February 12, 2020 Category: Anesthesiology Tags: Special Topic Series: Approach to Physical Activity in Pain: From Theory to the Lab, From Clinic to the Patient Source Type: research

Further Examination of the Pain stages of Change Questionnaires Among Chronic Low Back Pain Patients: Long-Term Predictive Validity of Pretreatment and Posttreatment Change Scores and Stability of Posttreatment Scores
No abstract available (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 3, 2020 Category: Anesthesiology Tags: Letter to the Editor Source Type: research

Conditioned Pain Modulation in Chronic Low Back Pain: A Systematic Review of Literature
Conclusions: High-quality research is strongly recommended to determine the function of endogenous pain modulatory mechanisms in CLBP. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 3, 2020 Category: Anesthesiology Tags: Review Articles Source Type: research

Relationships Between Psychological, Social, Physical Activity, and Sleep Measures and Somatosensory Function in Individuals With Spinal Pain: A Systematic Review and Meta-analysis
Conclusions: Psychological factors are associated negatively with pain thresholds and they need to be adjusted when establishing predictive relationships between somatosensory function and pain outcomes in individuals with spinal pain. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 3, 2020 Category: Anesthesiology Tags: Review Articles Source Type: research

Sleep Moderating the Relationship Between Pain and Health Care Use in Youth With Sickle Cell Disease
Conclusions: Findings suggest that good sleep may serve as a protective factor for better matching pain to HCU. Results should be interpreted in the context of study limitations. Research is needed to investigate possible mechanisms linking sleep duration to HCU in response to pain and to ascertain if sleep patterns influence the relationship between pain and other functional outcomes in youth with SCD. Clinically, these findings support the need to acknowledge and address the role that sleep plays in responding to SCD pain in pediatric populations. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 3, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Does Repeated Painful Stimuli Change Cerebral Near-Infrared Spectroscopy Response in Healthy, Term, Large for Gestational Age Newborns?
The objective of this study was to evaluate the effect of repeated painful stimuli on short-term pain response in healthy, term, large for gestational age newborns by measuring the regional cerebral oxygen saturation (rScO2), and behavioral and physiological responses. Methods: We compared term large for gestational age infants who received repeated painful stimuli (study group) with term, appropriate for gestational age infants (control group). A pulse oximeter and a near-infrared spectroscopy probe were connected to babies during the study period, and the responses of the babies were recorded by video, from which the ...
Source: The Clinical Journal of Pain - January 3, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Illusion-enhanced Virtual Reality Exercise for Neck Pain: A Replicated Single Case Series
Discussion: Our hypothesis, that neck exercises performed in VR with visual feedback of rotation amplified, would reduce persistent neck pain was not supported. Possible explanations and future directions are discussed. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 3, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Effects of Adding Oxycodone to Ropivacaine on Labor Analgesia: A Randomized Controlled Trial
Conclusions: This study demonstrates that epidural oxycodone may accelerate the onset of analgesia and obviously prolong the duration of analgesia during labor without increasing adverse effects associated with the neonate. However, it may cause a higher incidence of maternal pruritus (registration number: ChiCTR1800016483). (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 3, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

The Benefit of Dexmedetomidine on Postoperative Cognitive Function Is Unrelated to the Modulation on Peripheral Inflammation: A Single-center, Prospective, Randomized Study
Conclusion: Intraoperative sedation with dexmedetomidine conferred better postoperative neurocognitive function for elderly patients who received total knee arthroplasty. This effect was unrelated to the modulation of dexmedetomidine on peripheral inflammation. (Source: The Clinical Journal of Pain)
Source: The Clinical Journal of Pain - January 3, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research

Parents Reliably Identify Pain Dismissal by Pediatric Providers
This study examined parental reactions to dismissive provider-child scenarios and the influence of provider and patient sex on perceptions. Methods: Community parents (N=326) completed an online survey. Parents were randomized to listen to 1 of 8 vignettes of a provider-child chronic pain scenario. Vignettes varied by type of scenario (appropriate vs. dismissive)×provider sex×patient sex. Results: Overall, parents rated the dismissive scenario more negatively. There was a significant interaction between provider sex and scenario regarding likelihood to bring their own child to this provider and a signific...
Source: The Clinical Journal of Pain - January 3, 2020 Category: Anesthesiology Tags: Original Articles Source Type: research