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Total 228 results found since Jan 2013.

Characterizing the Penumbras of White Matter Hyperintensities and Their Associations With Cognitive Function in Patients With Subcortical Vascular Mild Cognitive Impairment
Conclusion In this study, reduced CBF and FA and increased MD in the inner NAWM layers for both PVWMH and DWMH suggested extensive WM alterations beyond the visible WM lesions commonly observed on clinical MRI of svMCI subjects. CBF penumbras cover more extensive WM at risk than DTI penumbras, suggesting the likelihood that compromised CBF precedes white matter integrity changes, and CBF penumbras may be a potential target for the prevention of further microstructural white matter damage. The imaging parameters investigated, however, did not correlate to cognition. Author Contributions YZ, QX, and XG conceived and desig...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Isolation of Antimicrobial Compounds From Cnestis ferruginea Vahl ex. DC (Connaraceae) Leaves Through Bioassay-Guided Fractionation
Conclusion In conclusion, aqueous extracts of C. ferruginea leaves showed antimicrobial activity due to the presence of hydroquinone and caffeic acid methyl ester. This supports its traditional use for infections and confirmed that the active molecules are water-soluble. Author Contributions KK, SP, LVP, and WL conceived and designed the experiments. SP, KK, M-RY, and J-GL performed the experiments. SP, LVP, WL, M-RY, J-GL, and Z-HJ analyzed the data. WL and Z-HJ contributed reagents, materials, and analysis tools. KK, SP, WL, M-RY, Z-HJ, and LVP contributed to the writing of the manuscript. All authors contributed to m...
Source: Frontiers in Microbiology - April 10, 2019 Category: Microbiology Source Type: research

Collectivism Is Associated With Greater Neurocognitive Fluency in Older Adults
This study aimed to evaluate the impact of self-construal on neurocognitive functions in older adults. A total of 86 community-dwelling older adults 60 years and older were assessed with three common self-report measures of self-construal along individualism and collectivism (IC). A cognitive battery was administered to assess verbal and non-verbal fluency abilities. Latent profile analysis (LPA) was used to categorize individuals according to IC, and one-way analyses of covariance (ANCOVA), including relevant covariates (e.g., ethnicity, gender, linguistic abilities), were used to compare neurocognitive functions between ...
Source: Frontiers in Human Neuroscience - April 10, 2019 Category: Neuroscience Source Type: research

Health-related quality of life among rural men and women with hypertension: assessment by the EQ-5D-5L in Jiangsu, China
ConclusionsThe HRQoL was lower in this rural hypertensive population than previously reported urban counterparts. To improve the HRQoL of hypertensive patients in rural areas, it is important to control hypertension and prevent its associated co-morbidities. More attention needs to be directed to elderly female patients with less education who scored much lower HRQoL than their male counterparts.
Source: Quality of Life Research - March 3, 2019 Category: Health Management Source Type: research

Association Between Medication Adherence and Admission Blood Pressure Among Patients With Ischemic Stroke
Conclusions: Stroke education in China should focus on patients' poor understanding of the importance for sustained antihypertensive medication adherence to improve blood pressure control and prevent stroke.
Source: Journal of Cardiovascular Nursing - February 16, 2019 Category: Nursing Tags: Feature Article/Online Only Source Type: research

Association between serum cholesterol levels and Alzheimer's disease in China: a case-control study.
Authors: Chen H, Du Y, Liu S, Ge B, Ji Y, Huang G Abstract To examine the association between blood cholesterol concentrations and Alzheimer's disease (AD) in the Chinese elderly. A case-control study was implemented between November 2011 and November 2017. Elderly patients aged ≥ 55 years with (n = 117) and without AD (control participants; n = 117) were recruited from the Neurology Central Hospital of Tianjin, China. The associations between AD and blood parameters were assessed using multiple binary logistic regression analyses adjusted for multiple covariates. Higher serum total cholesterol (TC) a...
Source: International Journal of Food Sciences and Nutrition - January 11, 2019 Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research

Sex Differences in the Prevalence of and Risk Factors for Cognitive Impairment No Dementia among the Elderly in a Rural Area of Northern China: A Population-Based Cross-Sectional Study
Conclusion: These findings suggest that it is crucial to address the secondary prevention of stroke and to consider the psychological status among the elderly with low educational attainment in order to reduce the burden of CIND in China.Neuroepidemiology 2019;52:25 –31
Source: Neuroepidemiology - November 26, 2018 Category: Epidemiology Source Type: research

The 2017 hormone therapy position statement of The North American Menopause Society
The 2017 Hormone Therapy Position Statement of The North American Menopause Society (NAMS) updates the 2012 Hormone Therapy Position Statement of The North American Menopause Society and identifies future research needs. An Advisory Panel of clinicians and researchers expert in the field of women's health and menopause was recruited by NAMS to review the 2012 Position Statement, evaluate new literature, assess the evidence, and reach consensus on recommendations, using the level of evidence to identify the strength of recommendations and the quality of the evidence. The Panel's recommendations were reviewed and approved by...
Source: Menopause - October 25, 2018 Category: OBGYN Tags: Commemorative Papers Source Type: research

The Efficacy of a Comprehensive Reminder System to Improve Health Behaviors and Blood Pressure Control in Hypertensive Ischemic Stroke Patients: A Randomized Controlled Trial
Conclusion: At 3 months, use of the Comprehensive Reminder System based on the Health Belief Model, yielded improvement in most health behaviors and blood pressure control in hypertensive ischemic stroke patients. Continued implementation of this intervention protocol is warranted to determine the long-term effect. Smoking and alcohol use behaviors need to be targeted with a different intervention.
Source: Journal of Cardiovascular Nursing - October 11, 2018 Category: Nursing Tags: ARTICLES: Prevention Source Type: research

Correlates of Emergency Department Service Utilization Among U.S. Chinese Older Adults
AbstractOlder adults visit emergency departments (EDs) at a disproportionally higher rate than other age groups. Prior studies examining racial disparities in ED utilization focus on African Americans and Hispanics. There is a dearth of information on ED utilization patterns among older Asian Americans despite the evidence that ED expenditures in Asian Americans are comparable to that of Caucasians. To address this knowledge gap, we examined factors associated with ED service utilization in the largest Asian subgroup, U.S. Chinese older adults. Cross-sectional data from the Population Study of Chinese Elderly in Chicago (P...
Source: Journal of Immigrant and Minority Health - October 9, 2018 Category: International Medicine & Public Health Source Type: research

Correlations Among Self-Rated Health, Chronic Disease, and Healthcare Utilization in Widowed Older Adults in Taiwan
Conclusions/Implications for Practice: These findings identified that chronic diseases and healthcare utilization correlated strongly with self-rated health for widowed older adults. Therefore, self-rated health may be used as a screening tool by the National Health Insurance System in Taiwan, and the results may be referenced by public health officials who are responsible for developing welfare strategies to promote healthy aging among the widowed in Taiwan.
Source: Journal of Nursing Research - September 8, 2018 Category: Nursing Tags: Original Articles Source Type: research

System-integrated technology-enabled model of care to improve the health of stroke patients in rural China: protocol for SINEMA--a cluster-randomized controlled trial
This study aims to develop a system-integrated technology-enabled intervention model of care (SINEMA) for the secondary prevention of stroke in rural China and to evaluate the effectiveness of the model compared with usual care.MethodsThe SINEMA model is being implemented and evaluated through a one-year cluster-randomized controlled trial in Nanhe County, Hebei Province in China. Fifty villages from five townships are randomized in a 1:1 ratio to either the intervention or the control arm (usual care) with a target to enroll 25 stroke survivors per village. Village doctors in the intervention arm 1) receive systematic cas...
Source: American Heart Journal - September 5, 2018 Category: Cardiology Source Type: research

Characterizing Beliefs about Stroke and Walking for Exercise among Seniors from Four Racial/Ethnic Minority Communities
We described and compared seniors ’ stroke-related health beliefs among four racial/ethnic communities to inform a culturally-tailored stroke prevention walking intervention. Specific attention was paid to how seniors combined pathophysiology-based biomedical beliefs with non-biomedical beliefs. We conducted twelve language-concor dant, structured focus groups with African American, Chinese American, Korean American, and Latino seniors aged 60 years and older with a history of hypertension (n = 132) to assess stroke-related health beliefs. Participants were asked their beliefs about stroke mechanism and prevention st...
Source: Journal of Cross-Cultural Gerontology - August 23, 2018 Category: Geriatrics Source Type: research

Sex Differences in the Prevalence of and Risk Factors for Nonvascular Cognitive Function in Rural, Low-Income Elderly in Tianjin, China
Conclusion: These findings suggest that it is crucial to manage and control hypertension and improve educational attainment in order to reduce the prevalence and burden of nonvascular cognitive impairment among low-income residents, both men and women, in rural China.Neuroepidemiology 2018;51:138 –148
Source: Neuroepidemiology - August 9, 2018 Category: Epidemiology Source Type: research