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Condition: Ischemic Stroke
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Total 2797 results found since Jan 2013.

The prevalence and prognosis of asymptomatic intracranial atherosclerosis in a community-based population: Results based on high-resolution magnetic resonance imaging
CONCLUSIONS: We found that ICAD detected using HR-MRI increases the long-term risk of a first-ever ischemic stroke in a stroke-free population, suggesting that the current primary prevention protocol of stroke awaits further optimization.PMID:37738517 | DOI:10.1111/ene.16057
Source: Atherosclerosis - September 22, 2023 Category: Cardiology Authors: Shengde Li Mingyu Tang Dingding Zhang Fei Han Lixin Zhou Ming Yao Mingli Li Liying Cui Shuyang Zhang Bin Peng Zhengyu Jin Yicheng Zhu Jun Ni Source Type: research

Bibliometric analysis and visualized study of research on autophagy in ischemic stroke
Conclusion: This bibliometric analysis helps us reveal the current research hotspots in the research field of autophagy in ischemic stroke and guide future research directions. Subsequent trends in this special field are likely to identify and develop novel autophagy-targeted therapy strategies to effectively prevent and treat ischemic stroke.PMID:37731738 | PMC:PMC10507179 | DOI:10.3389/fphar.2023.1232114
Source: Molecular Medicine - September 21, 2023 Category: Molecular Biology Authors: Jiefang Chen Gaijie Chen Xiaojing Xu Long Chen Jiewen Zhang Feng Liu Source Type: research

CNS-LAND score: predicting early neurological deterioration after intravenous thrombolysis based on systemic responses and injury
ConclusionCNS-LAND score is a reliable predictor of END risk in AIS patients receiving IVT.
Source: Frontiers in Neurology - September 21, 2023 Category: Neurology Source Type: research

Brain MRI correlations with disease burden and biomarkers in Fabry disease
ConclusionBrain MRI revealed progressive lacunar infarctions, white matter hyperintensities, and decreased brain volume in patients with Fabry disease. Brain MRI lesions were closely related to onset-age; disease duration, severity, burden; and plasma  Lyso-Gb3. However, they were not associated with sex, α-galactosidase A activity, orGLA mutation type.
Source: Journal of Neurology - September 20, 2023 Category: Neurology Source Type: research

Naotaifang formula attenuates OGD/R-induced inflammation and ferroptosis by regulating microglial M1/M2 polarization through BMP6/SMADs signaling pathway
CONCLUSION: Microglial M1/M2 polarization plays a pivotal role in inflammation and ferroptosis during OGD/R. The BMP6/SMADs signaling pathway is a potential therapeutical target of inflammation and ferroptosis induced by the transformation of microglia. Moreover, NTF could alleviate inflammation and ferroptosis through the BMP6/SMADs signaling pathway in OGD/R-injured microglia.PMID:37713988 | DOI:10.1016/j.biopha.2023.115465
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 15, 2023 Category: Drugs & Pharmacology Authors: Jun Liao Mengzhen Wei Jianjun Wang Jinsong Zeng Danhong Liu Qiusi Du Jinwen Ge Zhigang Mei Source Type: research

Risk factors and a prediction model for unruptured intracranial aneurysms in patients with ischemic stroke using carotid intima-media thickness and systemic atherosclerosis
CONCLUSION: The findings revealed that the risk factors for UIA in patients with IS included aspirin use, elevated CRP level, and smaller carotid IMT, and the predictive value of the prediction model was relatively better.PMID:37706007 | PMC:PMC10495834 | DOI:10.3389/fneur.2023.1227673
Source: Atherosclerosis - September 14, 2023 Category: Cardiology Authors: Gaiming Gao Dezhi Kang Jinning Zhang Zhixian Jiang Xueyang He Yanyu Wu Source Type: research

Sleep duration and risk of stroke and coronary heart disease: a 9-year community-based prospective study of 0.5 million Chinese adults
CONCLUSIONS: While abnormal sleep duration (≤ 6 h or ≥ 9 h) was associated with higher risks of CVD, the risks were more extreme for those reporting ≤ 5 or ≥ 10 h, respectively and such individuals should be prioritised for more intensive treatment for CVD prevention.PMID:37710209 | DOI:10.1186/s12883-023-03367-4
Source: Cancer Control - September 14, 2023 Category: Cancer & Oncology Authors: Yiping Chen Christiana Kartsonaki Robert Clarke Yu Guo Huaidong Du Canqing Yu Ling Yang Pei Pei Rebecca Stevens Sushila Burgess Yujie Hua Junshi Chen Jun Lv Liming Li Zhengming Chen China Kadoorie Biobank Collaborative Group Source Type: research

Risk factors and a prediction model for unruptured intracranial aneurysms in patients with ischemic stroke using carotid intima-media thickness and systemic atherosclerosis
CONCLUSION: The findings revealed that the risk factors for UIA in patients with IS included aspirin use, elevated CRP level, and smaller carotid IMT, and the predictive value of the prediction model was relatively better.PMID:37706007 | PMC:PMC10495834 | DOI:10.3389/fneur.2023.1227673
Source: Atherosclerosis - September 14, 2023 Category: Cardiology Authors: Gaiming Gao Dezhi Kang Jinning Zhang Zhixian Jiang Xueyang He Yanyu Wu Source Type: research

Sleep duration and risk of stroke and coronary heart disease: a 9-year community-based prospective study of 0.5 million Chinese adults
There is uncertainty about the optimum sleep duration for risk of different subtypes of stroke and ischaemic heart disease.
Source: BMC Neurology - September 14, 2023 Category: Neurology Authors: Yiping Chen, Christiana Kartsonaki, Robert Clarke, Yu Guo, Huaidong Du, Canqing Yu, Ling Yang, Pei Pei, Rebecca Stevens, Sushila Burgess, Yujie Hua, Junshi Chen, Jun Lv, Liming Li and Zhengming Chen Tags: Research article Source Type: research

Predictors of failure of early neurological improvement in early time window following endovascular thrombectomy: a multi-center study
ConclusionDiabetes mellitus history, pre-stroke mRS, longer last known well-to-puncture time, lack of modified thrombolysis in cerebral infarction = 3, and the number of mechanical thrombectomy passes are the predictors of FENI. Future large-scale studies are required to validate these findings.
Source: Frontiers in Neurology - September 14, 2023 Category: Neurology Source Type: research

High-Sensitivity C-reactive Protein and Intracranial Arterial Stenosis Predicted Recurrent Stroke and Dependence or Death in Minor Stroke or Transient Ischemic Attack
CONCLUSION: Concomitant presence of increased hsCRP levels and ICAS was associated with increased risk of stroke recurrence and dependence or death in patients with minor ischemic stroke or transient ischemic attack.PMID:37704441 | DOI:10.5551/jat.64229
Source: Journal of Atherosclerosis and Thrombosis - September 13, 2023 Category: Cardiology Authors: Jiejie Li Yuesong Pan Mengxing Wang Xia Meng Jinxi Lin Zixiao Li Hao Li Yilong Wang Xingquan Zhao Liping Liu Yongjun Wang Source Type: research