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Condition: Depression
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Total 1020 results found since Jan 2013.

Association of Major Depressive Episodes With Stroke Risk in a Prospective Study of 0.5 Million Chinese Adults Clinical Sciences
Conclusions— Findings from this large prospective study suggest that the presence of MDE is a risk factor for stroke, especially in smokers.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Sun, J., Ma, H., Yu, C., Lv, J., Guo, Y., Bian, Z., Yang, L., Chen, Y., Shen, H., Chen, Z., Hu, Z., Li, L., on behalf of the China Kadoorie Biobank Collaborative Group Tags: Mental Health, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Prevalence of suicidal ideation among stroke survivors: A systematic review and meta-analysis.
Conclusions: This meta-analysis suggests a high prevalence of SI among stroke survivors. Routine screening of SI after stroke is needed to plan interventions aimed at reducing suicide risk. PMID: 33186090 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - November 13, 2020 Category: Neurology Authors: Chen X, Zhang H, Xiao G, Lv C Tags: Top Stroke Rehabil Source Type: research

Stigma experienced by Chinese patients with stroke during inpatient rehabilitation and its correlated factors: a cross-sectional study.
CONCLUSIONS: Stigma was moderate, and internalized stigma may be more apparent; therefore, physicians should pay more attention to patients who report or show signs of experiencing stroke-related stigma. PMID: 31104577 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - May 18, 2019 Category: Neurology Authors: Zhu M, Zhou H, Zhang W, Deng Y, Wang X, Zhang X, Yang L, Li M, Bai X, Lin Z Tags: Top Stroke Rehabil Source Type: research

Factors associated with quality of life early after ischemic stroke: the role of resilience.
DISCUSSION: Resilience was an independent predictor of quality of life beyond anxiety and depression in patients with ischemic stroke. Interventions aimed at improving resilience at acute hospitalization might be a worthwhile addition to improve quality of life early after stroke. PMID: 30957683 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - April 7, 2019 Category: Neurology Authors: Liu Z, Zhou X, Zhang W, Zhou L Tags: Top Stroke Rehabil Source Type: research

Reliability and validity of a Chinese version of the Stigma Scale for Chronic Illness (SSCI) in patients with stroke.
Discussion The results provide initial evidence that the SSCI is a reliable and validated measure for evaluating stigma in stroke patients in China. PMID: 30900522 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - March 21, 2019 Category: Neurology Authors: Lu Q, Deng C, Fu L, Wu R, Chang L, Qi H, Wang K, Jiang L, Yang X, Wang Y, Li L, Zhao Y Tags: Top Stroke Rehabil Source Type: research

Impact of rehabilitation adherence and depressive symptoms on post-stroke self-care ability and quality of life: a longitudinal study
CONCLUSION: Both depressive symptoms and rehabilitation adherence behavior impacted the rehabilitation effect among patients who are recovering from a stroke.PMID:37722691 | DOI:10.1080/10749357.2023.2259652
Source: Topics in Stroke Rehabilitation - September 18, 2023 Category: Neurology Authors: Jeng Wang Wen-Yu Kuo Min-Chi Chen Chen-Yin Chen Source Type: research

Decreased Serum Netrin-1 as a Predictor for Post-Stroke Depression in Chinese Patients with Acute Ischemic Stroke
Experimental studies demonstrated that netrin-1 (NT-1) is an important factor influencing the recovery after ischemic stroke. However, whether NT-1 levels were associated with the post-stroke depression (PSD) remains unclear. We aimed to evaluate the relationship between NT-1 levels and PSD at 3 months in patients with ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Zhuo Chen, Tianli Cao, Xingju Zhong, Yong Wu, Wei Fu, Chaoli Fan, Yu Jiang, Yan Zhu, Jie Peng, Ping Li, Jingyu Tan Source Type: research

Factors Associated with Post-Stroke Depression in Chinese Stroke Survivors
To explore the relationship between participation self-efficacy, sociodemographic and clinical characteristics, and post-stroke depression in stroke survivors and provide insights into the development of rehabilitation programmes.
Source: Journal of Stroke and Cerebrovascular Diseases - September 7, 2021 Category: Neurology Authors: Janita P C Chau, Suzanne H S Lo, Jie Zhao, Kai Chow Choi, Simon K Y Lam, Laveeza Butt, David R Thompson Source Type: research

Effect of Inflammation on the Process of Stroke Rehabilitation and Poststroke Depression
Conclusions Stroke comprises ischemic stroke and ICH. The immuno-inflammatory process is involved in neural plasticity following events such as a hemorrhage or ischemic stroke. After ischemia, astrocytes, microglia, and MDMs play important roles during rehabilitation with the modulation of cytokines or chemokines, such as TNF-α and IL-1. Moreover, MiRNAs are also important posttranscriptional regulators in these glial mitochondrial responses to cerebral ischemia. ICH involves processes similar and different to those seen in ischemia, including neuronal injury, astrocytic and microglial/macrophage activation, and n...
Source: Frontiers in Psychiatry - April 10, 2019 Category: Psychiatry Source Type: research

Anxiety in Patients With Acute Ischemic Stroke: Risk Factors and Effects on Functional Status
Conclusion: Depressive symptoms are the major correlates of PSA while more severe PSA is associated with poorer ADL and health-related QOL. Acute lesions involving CHWM may correlate with PSA in ischemic stroke patients with mild-to-moderate neurologic deficits, supporting a lesion-location hypothesis in PSA.IntroductionAnxiety is prevalent after stroke and occurs in about one-quarter of stroke survivors (1, 2). Poststroke anxiety (PSA) may have a negative impact on quality of life (QOL) of stroke survivors, affecting their rehabilitation (3). Furthermore, one prospective study found that severe anxiety symptoms were assoc...
Source: Frontiers in Psychiatry - April 16, 2019 Category: Psychiatry Source Type: research

A Post-hoc Study of D-Amino Acid Oxidase in Blood as an Indicator of Post-stroke Dementia
In conclusion, our data support that plasma DAO levels were increased in PSD patients and correlated with brain WMH, independent of age, gender, hypertension, and renal function. Plasma DAO levels may therefore aid in PSD diagnosis. Introduction Stroke is a risk factor for both vascular dementia and Alzheimer's disease (1, 2). Functional recovery develops over the course of 26 weeks after a stroke (3), but the survivors are often left with disabilities. In addition to the sequelae of acute neuronal damage, the 1-year post-stroke dementia (PSD) rates after first-ever and recurrent stroke are ~10 and 30...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Post-stroke depression: different characteristics based on follow-up stage and gender-a cohort perspective study from Mainland China.
CONCLUSION: PSD is common in stroke survivors, and female patients have higher prevalence of PSD. Risk factors for PSD in the acute phase are different from that in the chronic phase of stroke. Female gender is an independent risk factor for PSD in the acute stage of stroke. Smoking, frontal lobe lesion, and living alone are predictive factors for PSD in the chronic stage of stroke. NIHSS score is a risk factor for PSD both in the acute and in the chronic stage of stroke. Further studies are needed to understand the mechanisms underlying the elevated prevalence of PSD in female. PMID: 28828931 [PubMed - as supplied by publisher]
Source: Neurological Research - August 24, 2017 Category: Neurology Tags: Neurol Res Source Type: research

The association analysis between CYP24A1 genetic polymorphisms and the risk of ischemic stroke in Chinese Han population
ConclusionOur study gave the evidences thatCYP24A1 genetic polymorphisms were significantly associated with ischemic stroke patients, which would provide useful information of assessment or possible diagnostic markers for ischemic stroke.
Source: Brain and Behavior - December 23, 2019 Category: Neurology Authors: Wei Yang, Fenghui Ma, Li Wang, Xue He, Hengxun Zhang, Jianwen Zheng, Yuhe Wang, Tianbo Jin, Dongya Yuan, Yongjun He Tags: ORIGINAL RESEARCH Source Type: research

Shared genetic risk factors for depression and stroke
ConclusionThese findings suggest that shared genetic pathways may contribute to the comorbidity of MDD and stroke. Studies to evaluate the shared genetic variations between MDD and stroke may provide insights into the molecular mechanisms that trigger disease progression.
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - March 20, 2019 Category: Psychiatry Source Type: research