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Condition: Arteriosclerosis
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Total 577 results found since Jan 2013.
Endothelial Nitric Oxide Synthase (eNOS) and the Cardiovascular System: in Physiology and in Disease States
Am J Biomed Sci Res. 2022;15(2):153-177. Epub 2022 Jan 4.ABSTRACTEndothelial nitric oxide synthase (eNOS) plays a critical role in regulating and maintaining a healthy cardiovascular system. The importance of eNOS can be emphasized from the genetic polymorphisms of the eNOS gene, uncoupling of eNOS dimerization, and its numerous signaling regulations. The activity of eNOS on the cardiac myocytes, vasculature, and the central nervous system are discussed. The effects of eNOS on the sympathetic autonomic nervous system (SANS) and the parasympathetic autonomic nervous system (PANS), both of which profoundly influence the card...
Source: Biomed Res - January 24, 2022 Category: Research Authors: N Tran T Garcia M Aniqa S Ali A Ally S M Nauli Source Type: research
Fibrinolytic Enzyme - An Overview
Curr Pharm Biotechnol. 2022 Jan 4. doi: 10.2174/1389201023666220104143113. Online ahead of print.ABSTRACTCardiovascular diseases, like coronary heart disease or artery disorders (arteriosclerosis, including artery solidification), heart failure (myocardial infarction), arrhythmias, congestive heart condition, stroke, elevated vital signs (hypertension), rheumatic heart disorder, and other circulatory system dysfunctions are the most common causes of death worldwide. Cardiovascular disorders are treated with stenting, coronary bypass surgery grafting, anticoagulants, antiplatelet agents, and other pharmacological and surgic...
Source: Current Pharmaceutical Biotechnology - January 5, 2022 Category: Biotechnology Authors: None Parveen A None Devika R Source Type: research
Elevated Aortic Pulse Wave Velocity Relates to Longitudinal Gray and White Matter Changes
CONCLUSIONS: In older adults, higher baseline aortic PWV related to greater decrease in gray matter volume and greater increase in WMHs over time. Because of unmet cerebral metabolic demands and microvascular remodeling, arterial stiffening may preferentially affect certain highly active brain regions like the temporal lobes. These same regions are affected early in the course of Alzheimer disease.PMID:34706559 | DOI:10.1161/ATVBAHA.121.316477
Source: Arteriosclerosis, Thrombosis and Vascular Biology - October 28, 2021 Category: Cardiology Authors: Corey W Bown Omair A Khan Elizabeth E Moore Dandan Liu Kimberly R Pechman Francis E Cambronero James G Terry Sangeeta Nair L Taylor Davis Katherine A Gifford Bennett A Landman Timothy J Hohman John Jeffrey Carr Angela L Jefferson Source Type: research
Trimethylamine N-oxide-a marker for atherosclerotic vascular disease
Rev Cardiovasc Med. 2021 Sep 24;22(3):787-797. doi: 10.31083/j.rcm2203085.ABSTRACTAs a potential causative factor in various cardiovascular diseases, the gut microbe-generated metabolite trimethylamine N-oxide (TMAO) has courted considerable research interest as a potential biomarker. TMAO is a small molecule considered to be beneficial for the health of deep-water animals due to its ability to protect proteins against hydrostatic pressure stress. However, it may cause deleterious effects in humans as mounting evidence suggests that TMAO may enhance atherosclerosis, independent of traditional risk factors. This may be medi...
Source: Reviews in Cardiovascular Medicine - September 26, 2021 Category: Cardiology Authors: Guinan Xie An Yan Peng Lin Yi Wang Liping Guo Source Type: research
