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Condition: Arteriosclerosis

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Total 577 results found since Jan 2013.

RNA binding protein RPS3 mediates microglial polarization by activating NLRP3 inflammasome via SIRT1 in ischemic stroke
Stroke remains the leading cause of death and permanent disability worldwide and ischemic stroke represents 80% of all cases, which brings extremely serious consequences to the family and society.1 Ischemic stroke refers to the general term of cerebral blood supply artery stenosis or occlusion leading to cerebral blood circulation disorder, insufficient blood supply and brain tissue necrosis.2 Cerebral ischemic stroke occurs in middle-aged and elderly people, and arteriosclerosis and hypertension are the main pathogenic factors.
Source: Journal of Stroke and Cerebrovascular Diseases - April 21, 2023 Category: Neurology Authors: Dimi Zhou, Lin Chen, Yuzheng Wang, Lu Gan, Mei Yuan, Lei Zhang, Fenfang Chen Source Type: research

Bioinspired Approaches to Engineer Antithrombogenic Medical Devices for Vascular Intervention
Arterioscler Thromb Vasc Biol. 2023 Apr 20. doi: 10.1161/ATVBAHA.122.318238. Online ahead of print.ABSTRACTMedical devices form a critical component of health care systems for treating and maintaining patient health. However, devices exposed to blood are prone to blood clotting (thrombosis) and bleeding complications leading to device occlusion, device failure, embolism and stroke, and increased morbidity and mortality. Over the years, developments in innovative material design strategies have been made to help reduce the occurrence of thrombotic events on medical devices, but complications persist. Here, we review materia...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 20, 2023 Category: Cardiology Authors: Jun Ki Hong Anna Waterhouse Source Type: research

Sex Differences in Outcomes of Ticagrelor Therapy With or Without Aspirin After Percutaneous Coronary Intervention in Patients With Acute Coronary Syndrome: A Post Hoc Secondary Analysis of the TICO Randomized Clinical Trial
CONCLUSIONS: After percutaneous coronary intervention for acute coronary syndrome, women demonstrated worse clinical outcomes than men. Ticagrelor monotherapy after 3-month dual-antiplatelet therapy was associated with significantly lower risk of net adverse clinical events in women without sex interaction.PMID:37021576 | DOI:10.1161/ATVBAHA.122.318725
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 6, 2023 Category: Cardiology Authors: Bom Lee Seung-Jun Lee Byeong-Keuk Kim Yong-Joon Lee Sung-Jin Hong Chul-Min Ahn Jung-Sun Kim Young-Guk Ko Donghoon Choi Meyong-Ki Hong Yangsoo Jang Source Type: research

Clonal Hematopoiesis of Indeterminate Potential Is Associated With Coronary Microvascular Dysfunction In Early Nonobstructive Coronary Artery Disease
CONCLUSIONS: In humans, we observe patients with CMD are more likely to have CHIP, and nearly one-third of major adverse cardiovascular events in CMD are mediated by CH.PMID:36951061 | DOI:10.1161/ATVBAHA.122.318928
Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 23, 2023 Category: Cardiology Authors: Nadia Akhiyat Terra L Lasho Morsaleh Ganji Takumi Toya Chang-Xin Shi Xianfeng Chen Esteban Braggio Ali Ahmad Michel T Corban Keith Stewart Jenna Fernandez Zhuoer Xie Christy Finke Lilach O Lerman Mrinal M Patnaik Amir Lerman Source Type: research