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Trimethylamine N-oxide-a marker for atherosclerotic vascular disease
Rev Cardiovasc Med. 2021 Sep 24;22(3):787-797. doi: 10.31083/j.rcm2203085.ABSTRACTAs a potential causative factor in various cardiovascular diseases, the gut microbe-generated metabolite trimethylamine N-oxide (TMAO) has courted considerable research interest as a potential biomarker. TMAO is a small molecule considered to be beneficial for the health of deep-water animals due to its ability to protect proteins against hydrostatic pressure stress. However, it may cause deleterious effects in humans as mounting evidence suggests that TMAO may enhance atherosclerosis, independent of traditional risk factors. This may be medi...
Source: Reviews in Cardiovascular Medicine - September 26, 2021 Category: Cardiology Authors: Guinan Xie An Yan Peng Lin Yi Wang Liping Guo Source Type: research