Effect of lipoprotein(a) levels on long-term outcome in octogenarians with coronary artery disease after drug-eluting stent implantation
CONCLUSIONS: High Lp(a) was also significantly related to poor long-term outcome in octogenarians with CAD after DES implantation.PMID:35345246 | DOI:10.31083/j.rcm2303079 (Source: Reviews in Cardiovascular Medicine)
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Bin Hu Yujie Zhou Dongmei Shi Yingxin Zhao Dean Jia Shiwei Yang Shuo Jia Xiaohan Xu Xiaoteng Ma Source Type: research

Validation and Comparison of PROMISE and CONFIRM Model to Predict High-Risk Coronary Artery Disease in Symptomatic and Diabetes Mellitus Patients
CONCLUSIONS: Compared to CHM, PHM was associated with a more accurate prediction for HRCAD and might optimize downstream management strategy in symptomatic patients with DM.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov (NCT04691037).PMID:35345247 | DOI:10.31083/j.rcm2303080 (Source: Reviews in Cardiovascular Medicine)
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Hantao Jiang Jinping Feng Chao Feng Pei Ren Kai Ren Ying Jin Jia Zhou Source Type: research

Potent P2Y12 inhibitors versus clopidogrel to predict adherence to antiplatelet therapy after an acute coronary syndrome: insights from IDEAL-LDL
CONCLUSIONS: Adherence to DAPT was not affected by the P2Y12i potency, whereas history of CVD and PCI treatment were associated with reduced and increased adherence, respectively.CLINICAL TRIAL REGISTRATION: NCT02927808, https://clinicaltrials.gov/ct2/show/NCT02927808.PMID:35345248 | DOI:10.31083/j.rcm2303081 (Source: Reviews in Cardiovascular Medicine)
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Olga Kourti Orestis Konstantas Ioannis Τ Farmakis Stefanos Zafeiropoulos Georgios Psarakis Elena Vrana Amalia Baroutidou Spyridon Graidis Aikaterini-Vassiliki Touriki Christos Tsolakidis Konstantina Spyridaki Thomas Psathas Anastasia Daniilidou Haralambo Source Type: research

The role of sodium-glucose co-transporter (SGLT)-2 inhibitors in heart failure management and implications for the kidneys
Rev Cardiovasc Med. 2022 Mar 3;23(3):82. doi: 10.31083/j.rcm2303082.ABSTRACTSodium-glucose co-transporter (SGLT)-2 inhibitors were initially developed for management of type 2 diabetes but have been shown to offer improved outcomes in heart failure, a condition in which concomitant chronic kidney disease (CKD) is common. Randomised controlled trials initially demonstrated prognostic cardiovascular and renal benefits of SGLT2 inhibitors in high cardiovascular risk individuals with type 2 diabetes particularly in relation to heart failure. Improved outcomes have been replicated in cohorts with established heart failure and/o...
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Eirini Lioudaki Jennifer Ruth Joslin Eirini Trachanatzi Emmanuel Androulakis Source Type: research

Energy drink consumption: a rising public health issue
Rev Cardiovasc Med. 2022 Mar 4;23(3):83. doi: 10.31083/j.rcm2303083.ABSTRACTEnergy drink (ED) consumption has become a growing public health issue over the past few decades. Despite claims of being safe and beneficial, EDs have been linked to particularly fatal outcomes associated with the cardiovascular system which include atrial and ventricular arrhythmias, myocardial infarctions, cardiomyopathies, and sudden cardiac death. Large quantities of caffeine, taurine, sugars, and B-vitamins may be contributing to these outcomes by increasing the heart rate, blood pressure (BP), and contractility of the heart in addition to pr...
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Amandeep Kaur Hamza Yousuf Devyani Ramgobin-Marshall Rahul Jain Rohit Jain Source Type: research

Remifentanil versus Dexmedetomidine in Cardiac Surgery Patients with Noninvasive Ventilation Intolerance: Protocol for the REDNIVI Trial
CONCLUSIONS: This trial will provide evidence to determine the effects of remifentanil and dexmedetomidine in patients with NIV intolerance after cardiac surgery.CLINICAL TRIAL REGISTRATION: This study has been registered on ClinicalTrials.gov (NCT04734418).PMID:35345251 | DOI:10.31083/j.rcm2303084 (Source: Reviews in Cardiovascular Medicine)
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Ming-Hao Luo Guang-Wei Hao Kai Liu Kanhua Yin Shen-Ji Yu Huan Wang Ying Su Jing-Chao Luo Yong-Qi Wei Yu-Hang Wang Wen-Qi Pan Guo-Wei Tu Zhe Luo Source Type: research

Individualized right ventricular outflow tract reconstruction using autologous pulmonary tissue in situ for the treatment of pulmonary atresia with ventricular septum defect
CONCLUSION: Individualized RVOT reconstruction with autologous pulmonary tissue preserved in situ as the posterior wall is adequate for treating PA-VSD.PMID:35345252 | DOI:10.31083/j.rcm2303085 (Source: Reviews in Cardiovascular Medicine)
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Ming Wu Chengming Fan Jian Liu Chukwuemeka Daniel Iroegbu Wangping Chen Peng Huang Mi Tang Xun Wu Chunle Wang Kun Xiang Wenwu Zhou Jinfu Yang Source Type: research

Rest contrast echocardiography unmasks hidden wall motion abnormalities in patients with chest pain. A case series and review of pertinent literature
We present a case series of three patients that underwent myocardial contrast echocardiography (MCE) in the setting of recent chest pain, as paradigmatic examples of the usefulness of contrast-echocardiography with very-low mechanical index imaging in the context of rest wall motion assessment. Moreover, we analysed the pertinent literature about the use of rest MCE in the context of chest pain of unknown origin, showing its diagnostic and prognostic impact. We think that MCE could play a key role in detecting chest pain subtended by previously unknown coronary artery disease (CAD). For example, in pts without significant ...
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Sergio Suma Domenico Tuttolomondo Nicola Gaibazzi Source Type: research

The role of surgery for secondary mitral regurgitation and heart failure in the era of transcatheter mitral valve therapies
Rev Cardiovasc Med. 2022 Mar 4;23(3):87. doi: 10.31083/j.rcm2303087.ABSTRACTThe approach to the management of mitral valve (MV) disease and heart failure (HF) has dramatically changed over the last decades. It is well recognized that severe mitral regurgitation secondary to ischemic or non-ischemic cardiomyopathy is associated with an excess risk of mortality. Understanding the impact of the surgical treatment modality on mortality outcomes has been difficult due to the broad spectrum of secondary mitral regurgitation (SMR) phenotypes and lack of randomized surgical clinical trials. Over the last 30 years, surgeons have fa...
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Pierre-Emmanuel Noly Fran çis D Pagani Jean-Fan çois Obadia Denis Bouchard Steven F Bolling Gorav Ailawadi Paul C Tang Source Type: research

Learning from Controversy and Revisiting the Randomized Trials of Secondary Mitral Regurgitation
Rev Cardiovasc Med. 2022 Mar 4;23(3):88. doi: 10.31083/j.rcm2303088.ABSTRACTUntil recently, conventional mitral valve surgery has been the treatment of choice even in secondary mitral regurgitation. Recent evidence, however, advocates the use of transcatheter edge-to-edge mitral valve repair (TEER) of the mitral valve. This has been reflected by the change in guidelines of the American College of Cardiology/American Heart Association. We reviewed the literature to shed light on the risks and benefits of all interventions, surgical, transcatheter and guideline-directed medical therapy. Secondary mitral regurgitation occurs ...
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Antonio Fiore Sanjeet Singh Avtaar Singh Francesco Nappi Source Type: research

Protection of Exogenous Phosphocreatine for Myocardium in Percutaneous Coronary Intervention Related to Inflammation
CONCLUSIONS: Exogenous phosphocreatine reduces stent implantation, triggers inflammation manifested as decreased serum levels of IL-6 and the aggregation of neutrophils, and protects the myocardium of the patients undergoing PCI. These findings provided the potential mechanism and treatment for myocardial injury associated with PCI.PMID:35345256 | DOI:10.31083/j.rcm2303089 (Source: Reviews in Cardiovascular Medicine)
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Ming-Ying Ling Yi-Ping Song Chun Liu Zhi-Hao Wang Yan Wang Xue-Hui Li Zhen Zhang Rong-Xiang Zhou Liang-Yi Qie Man Li Yun-Ling Xiao Huan-Qin Chen Yan-Qiu Xing Source Type: research

Current Opinions on New-Onset Left Bundle Branch Block after Transcatheter Aortic Valve Replacement and the Search for Physiological Pacing
Rev Cardiovasc Med. 2022 Mar 9;23(3):90. doi: 10.31083/j.rcm2303090.ABSTRACTTranscatheter aortic valve replacement possesses a high validity for patients with aortic stenosis who are considered high risk for aortic valve replacement surgery, nowadays it is also considered for patients with intermediate risk or even lower risk in certain situations. The incidence of new conduction abnormalities remains to be a tough problem, in particular, left bundle branch block. New-onset left bundle branch block is a major concern despite improvements in valve technology, and it may affect postoperative prognosis. Understanding the anat...
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Jiefang Zhang Yiwen Pan Bei Wang Guosheng Fu Source Type: research

Cardiovascular events after liver transplantation: MACE hurts
Rev Cardiovasc Med. 2022 Mar 9;23(3):91. doi: 10.31083/j.rcm2303091.ABSTRACTThe curative therapy for patients with end-stage liver disease is liver transplantation. However, liver transplantation challenges the cardiovascular system, and is associated with major adverse cardiovascular events (MACE). Immediately after implantation of the liver graft, changes in cardiac preload and afterload increase the cardiac workload. Longer-term postoperatively, a more sedentary lifestyle and enhanced appetite increase obesity and body mass index. Immunosuppressants may also affect the cardiovascular system. All these factors that liver...
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Mario H Altieri Hongqun Liu Samuel S Lee Source Type: research

Comparison of Different Thoracic Aortic Wall Characteristics for Assessment of Disease Activity in Takayasu Arteritis: A Quantitative Study with 3.0 T Magnetic Resonance Imaging
CONCLUSIONS: MRI enabled the comprehensive assessment of aortic wall morphology and functional markers for TAK disease activity. Aortic maximal wall thickness was the most accurate indicator of TAK activity. The early phase was superior to the delay phase for aortic wall enhancement analysis for assessing TAK activity.PMID:35345259 | DOI:10.31083/j.rcm2303092 (Source: Reviews in Cardiovascular Medicine)
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Nan Zhang Lili Pan Jiayi Liu Yu Li Lei Xu Zhonghua Sun Zhenchang Wang Source Type: research

Hyperacute Incidental Late Myocardial Enhancement in Ischemic Stroke Using Chest Spectral CT: Relationship with Etiology
CONCLUSIONS: In this study, hyperacute cardiac imaging of AIS with DESCT identified a high prevalence of incidental cardiac disease predominantly involving LIE of ischemic etiology and mostly not related to the stroke etiology.PMID:35345260 | DOI:10.31083/j.rcm2303093 (Source: Reviews in Cardiovascular Medicine)
Source: Reviews in Cardiovascular Medicine - March 29, 2022 Category: Cardiology Authors: Gaston A Rodriguez-Granillo Juan J Cirio Celina Ciardi Maria L Caballero Lucia A Fontana Mariano D Buezas Pablo Diluca Pedro Lylyk Source Type: research