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Condition: Arteriosclerosis

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Total 577 results found since Jan 2013.

Aggressive LDL-C Lowering and the Brain: Impact on Risk for Dementia and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association
The objective of this scientific statement is to evaluate contemporary evidence that either supports or refutes the conclusion that aggressive low-density lipoprotein cholesterol lowering or lipid lowering exerts toxic effects on the brain, leading to cognitive impairment or dementia or hemorrhagic stroke. The writing group used literature reviews, references to published clinical and epidemiology studies, clinical and public health guidelines, authoritative statements, and expert opinion to summarize existing evidence and to identify gaps in current knowledge. Although some retrospective, case control, and prospective lon...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - September 14, 2023 Category: Cardiology Authors: Larry B Goldstein Peter P Toth Jennifer L Dearborn-Tomazos Robert P Giugliano Benjamin J Hirsh Jessica M Pe ña Magdy H Selim Daniel Woo American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Source Type: research

PAD4-Induced NETosis Via Cathepsin G-Mediated Platelet-Neutrophil Interaction in ChAdOx1 Vaccine-Induced Thrombosis
CONCLUSIONS: Patients with VITT display enhanced thrombogenesis by PAD4-mediated NETs formation via cathepsin G-mediated platelet/neutrophil interaction.PMID:37586040 | DOI:10.1161/ATVBAHA.123.319522
Source: Arteriosclerosis, Thrombosis and Vascular Biology - August 16, 2023 Category: Cardiology Authors: Roberto Carnevale Martina Leopizzi Marcello Dominici Giulia d'Amati Simona Bartimoccia Cristina Nocella Vittoria Cammisotto Alessandra D'Amico Valentina Castellani Francesco Baratta Alessia Bertelli Alessio Arrivi Danilo Toni Manuela De Michele Pasquale P Source Type: research

Differences in symmetrical low-frequency oscillations among healthy subjects, and those with stroke or peripheral arterial disease
Conclusions: LFOs can serve as vascular perfusion biomarkers to differentiate types and degrees of vascular lesions. Therefore, LFOs have the potential to provide valuable patient information to assist researchers and clinicians in identifying specific peripheral circulatory damage subgroups.PMID:37484434 | PMC:PMC10361110 | DOI:10.1016/j.heliyon.2023.e17015
Source: Atherosclerosis - July 24, 2023 Category: Cardiology Authors: Yunfei Ma Kexin Luo Peng Ding Shimin Yin Xiaoli Li Yingwei Li Source Type: research

Tmax volume can predict clinical type in patients with acute ischemic stroke
CONCLUSION: The Tmax volume derived from perfusion imaging predicts the clinical classification of AIS patients before EVT.PMID:37469274 | DOI:10.1002/brb3.3163
Source: Atherosclerosis - July 20, 2023 Category: Cardiology Authors: Fumihisa Kishi Ichiro Nakagawa Seigo Kimura Daiji Ogawa Ryokichi Yagi Keiichi Yamada Hirokatsu Taniguchi Source Type: research

Noninvasive In Vivo Thrombus Imaging in Patients With Ischemic Stroke or Transient Ischemic Attack
CONCLUSIONS: 18F-GP1 positron emission tomography and computed tomography angiography is a novel noninvasive method of identifying in vivo cerebrovascular thrombosis, which holds major promise in understanding the role and origin of thrombosis in stroke.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT03943966.PMID:37439259 | DOI:10.1161/ATVBAHA.122.318204
Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 13, 2023 Category: Cardiology Authors: Beth Whittington Evangelos Tzolos Rong Bing Jack Andrews Christophe Lucatelli Mark G MacAskill Adriana A S Tavares Tim Clark Nicholas L Mills Jennifer Nash Damini Dey Piotr J Slomka Norman Koglin Andrew W Stephens Edwin J R van Beek Colin Smith Marc R Dwe Source Type: research

Independent Causal Effect of Remnant Cholesterol on Atherosclerotic Cardiovascular Outcomes: A Mendelian Randomization Study
CONCLUSIONS: This large-scale Mendelian randomization study showed a robust genetic causal association between RC and cardiovascular outcomes. The effect on CAD and MI is independent of LDL cholesterol. Early screening for RC along with long-term inhibition of RC should be the focus of future therapeutic interventions.PMID:37439258 | DOI:10.1161/ATVBAHA.123.319297
Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 13, 2023 Category: Cardiology Authors: Eliano P Navarese Donna Vine Spencer Proctor Klaudyna Grzelakowska Sergio Berti Jacek Kubica Paolo Raggi Source Type: research