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Condition: Aortic Stenosis

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Total 1228 results found since Jan 2013.

Clinical and Echocardiographic Outcomes Following Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement: Meta-Analysis and Meta-Regression Structural Heart Disease
Conclusions— PPM implantation is not associated with increased risk of all-cause mortality, cardiovascular mortality, stroke, or myocardial infarction both at short- and long-term follow-up. However, PPM is associated with impaired left ventricular ejection fraction recovery post-transcatheter aortic valve replacement.
Source: Circulation: Cardiovascular Interventions - July 11, 2017 Category: Cardiology Authors: Mohananey, D., Jobanputra, Y., Kumar, A., Krishnaswamy, A., Mick, S., White, J. M., Kapadia, S. R. Tags: Arrhythmias, Valvular Heart Disease, Catheter-Based Coronary and Valvular Interventions, Pacemaker Structural Heart Disease Source Type: research

Lower Transaortic Flow Rate Is Associated With Increased Mortality in Aortic Valve Stenosis
Conclusions In patients with AS without known cardiovascular disease or diabetes, low transaortic FR was independently associated with higher rates of cardiovascular and all-cause mortality. (An Investigational Drug on Clinical Outcomes in Patients With Aortic Stenosis (Narrowing of the Major Blood Vessel of the Heart) (MK-0653A-043 AM4); NCT00092677)
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - August 7, 2017 Category: Radiology Authors: Saeed, S., Senior, R., Chahal, N. S., Lonnebakken, M. T., Chambers, J. B., Bahlmann, E., Gerdts, E. Tags: Original Research Source Type: research

Dynamic changes in aortic impedance after transcatheter aortic valve replacement and its impact on exploratory outcome
AbstractValvulo-arterial impedance (Zva) has been shown to predict worse outcome in medically managed aortic stenosis (AS) patients. We aimed to investigate the association between Zva and left ventricular (LV) adaptation and to explore the predictive value of Zva for cardiac functional recovery and outcome after transcatheter aortic valve replacement (TAVR). We prospectively enrolled 128 patients with AS who underwent TAVR. Zva was calculated as: (systolic blood pressure  + mean transaortic gradient)/stroke volume index). Echocardiographic assessment occurred at baseline, 1-month and 1-year after TAVR. The primary end...
Source: The International Journal of Cardiovascular Imaging - November 1, 2017 Category: Radiology Source Type: research

Comparative analysis of balloon- versus mechanically-expandable transcatheter heart valves considering landing zone calcification.
CONCLUSION: Both THVs yield comparable procedural and clinical outcomes except for a higher PPI rate with the Lotus valve, which is independent from the extent of landing zone calcification. The extent of landing zone calcification is associated with an increased risk for PVL for both THV, but is significantly reduced with the Lotus valve. PMID: 29548665 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - March 13, 2018 Category: Cardiology Authors: Schofer N, Deuschl F, Schön G, Seiffert M, Linder M, Schaefer A, Schirmer J, Lubos E, Reichenspurner H, Blankenberg S, Conradi L, Schäfer U Tags: J Cardiol Source Type: research

Midterm outcome of transcatheter versus surgical aortic valve replacement in low to intermediate risk patients: A meta-analysis of randomized controlled trials.
CONCLUSION: In patients at low to intermediate surgical risk, midterm clinical outcomes of TAVR were similar to SAVR in survival and stroke rate, superior in reducing life-threatening bleeding, acute kidney injury, and new-onset atrial fibrillation, but inferior in increasing permanent pacemaker implantation. PMID: 29655505 [PubMed - in process]
Source: Journal of Cardiology - April 17, 2018 Category: Cardiology Authors: Wang Y, Zhou Y, Zhang L, Zhu J Tags: J Cardiol Source Type: research

Operative risk of geriatric patients in cardiac surgery.
CONCLUSION: The perioperative mortality of older patients in cardiac surgery is low. A limited functional status detected in the geriatric assessment is associated with an increased mortality. Impaired cognitive function is an independent predictor of postoperative mortality. PMID: 29796869 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Gerontologie und Geriatrie - May 23, 2018 Category: Geriatrics Authors: Frilling B, von Renteln-Kruse W, Rösler A, Rieß FC Tags: Z Gerontol Geriatr Source Type: research

Transcatheter aortic valve implantation with the self-expanding Portico ™ valve system in an all-comers population: procedural and clinical outcomes.
CONCLUSIONS: The PorticoTM TAVI system was safe to implant and achieved a high device success rate. With learning curve effects, the device achieves lower rates of PVL and pacemaker implantation and provides adequate clinical and hemodynamic outcomes through 1 year. PMID: 29969432 [PubMed - as supplied by publisher]
Source: EuroIntervention - July 5, 2018 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Cognition and Cerebral Infarction in Older Adults After Surgical Aortic Valve Replacement
ConclusionsIn high-risk, aged participants undergoing surgical AVR for aortic stenosis, post-operative cognitive dysfunction was surprisingly limited and was resolved by 1-year in most. Post-operative cognitive dysfunction at 4-6 weeks was associated with more and larger acute cerebral infarcts.
Source: The Annals of Thoracic Surgery - November 11, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Cognition and Cerebral Infarction in Older Adults After Surgical Aortic Valve Replacement.
CONCLUSIONS: In high-risk, aged participants undergoing surgical AVR for aortic stenosis, post-operative cognitive dysfunction was surprisingly limited and was resolved by 1-year in most. Post-operative cognitive dysfunction at 4-6 weeks was associated with more and larger acute cerebral infarcts. PMID: 30423336 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - November 10, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Giovannetti T, Price CC, Fanning M, Messé S, Ratcliffe SJ, Lyon A, Kasner SE, Seidel G, Bavaria JE, Szeto WY, Hargrove WC, Acker MA, Floyd TF, DENOVO Investigators Tags: Ann Thorac Surg Source Type: research

Analysis of Neurologic Complications After Surgical Versus Transcatheter Aortic Valve Replacement
Ove the last decade, transcatheter aortic valve replacement (TAVR) has emerged as the recommended approach over surgical aortic valve replacement (SAVR) for many patients with aortic stenosis. While initial trials demonstrated a higher incidence of stroke with TAVR compared to SAVR, the incidence of stroke appears to have improved over time. With the increasing number of patients expected to undergo TAVR in the coming decades, it is important to review the incidence and etiology of stroke after SAVR and TAVR.
Source: Journal of Cardiothoracic and Vascular Anesthesia - December 27, 2018 Category: Anesthesiology Authors: Sundar Krishnan, Archit Sharma, Sudhakar Subramani, Lovkesh Arora, Divyanshu Mohananey, Pedro Villablanca, Harish Ramakrishna Tags: Expert Review Source Type: research

Mid-Term Outcomes after Transapical and Transfemoral Transcatheter Aortic Valve Implantation for Aortic Stenosis and Porcelain Aorta with a Systematic Review of Transfemoral versus Transapical Approach
Conclusion TA-TAVI shows promising early and mid-term outcomes in patients with PAo. TF-TAVI performed in patients with PAo is likely to be associated with higher rates of stroke than TA-TAVI. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: The Thoracic and Cardiovascular Surgeon - June 25, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Useini, Dritan Haldenwang, Peter Schl ömicher, Markus Christ, Hildegard Naraghi, Hamid Moustafine, Vadim Strauch, Justus Tags: Original Cardiovascular Source Type: research

Mid-Term Outcomes after Transapical and Transfemoral Transcatheter Aortic Valve Implantation for Aortic Stenosis and Porcelain Aorta with a Systematic Review of Transfemoral versus Transapical Approach.
CONCLUSION:  TA-TAVI shows promising early and mid-term outcomes in patients with PAo. TF-TAVI performed in patients with PAo is likely to be associated with higher rates of stroke than TA-TAVI. PMID: 31242522 [PubMed - as supplied by publisher]
Source: The Thoracic and Cardiovascular Surgeon - June 25, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Useini D, Haldenwang P, Schlömicher M, Christ H, Naraghi H, Moustafine V, Strauch J Tags: Thorac Cardiovasc Surg Source Type: research

Outcomes in nonagenarians undergoing transcatheter aortic valve implantation (TAVI): data from a nationwide analysis.
CONCLUSIONS: Within nonagenarians with AS, patients treated with TAVI had lower risk of cardiovascular events than matched patients treated medically. The patients undergoing a TAVI at this age were often highly selected and the procedure was associated with acceptable long term outcomes. PMID: 31763981 [PubMed - as supplied by publisher]
Source: EuroIntervention - November 27, 2019 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk.
CONCLUSIONS: Our meta-analysis indicates that, in the short term, TAVI probably has little or no mortality difference compared to SAVR for severe AS in individuals with low surgical risk. Similarly, there is probably little or no difference in risk of stroke, MI, and cardiac death between the two approaches. TAVI may reduce the risk of rehospitalisation, but we are uncertain about the effects on LOS. TAVI reduces the risk of atrial fibrillation, AKI, and bleeding. However, this benefit is offset by the increased risk of PPM implantation. Long-term follow-up data are needed to further assess and validate these outcomes, esp...
Source: Cochrane Database of Systematic Reviews - December 19, 2019 Category: General Medicine Authors: Kolkailah AA, Doukky R, Pelletier MP, Volgman AS, Kaneko T, Nabhan AF Tags: Cochrane Database Syst Rev Source Type: research

Surgical vs transfemoral aortic valve replacement in low ‐risk patients: An updated meta‐analysis of trial and registry data
ConclusionsEarly mortality is higher in SAVR while rates of PVL and PPMI are substantially higher in TAVR. There is no significant advantage with TAVR for overall survival, cardiovascular death, stroke, MI, and re ‐intervention rates.
Source: Journal of Cardiac Surgery - July 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Suvitesh Luthra, Miguel M. Leiva ‐Juárez, Sunil K. Ohri Tags: ORIGINAL ARTICLE Source Type: research