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Condition: Aortic Stenosis

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Total 1228 results found since Jan 2013.

TAVR Vs Standard Surgery: Midterm Stroke, Death Rates Comparable
All-cause and cardiovascular mortality were similar for transaortic valve replacement compared to open-heart surgery in high-risk older patients at three years with no increased risk of stroke after 30 days, according to results from the PARTNER study presented at the American College of Cardiology's 62nd Annual Scientific Session. The transcatheter aortic valve replacement (TAVR) system was investigated as an alternative to open-heart surgery for high-risk patients with severe aortic stenosis - narrowing of a main circulatory gateway in the heart that reduces blood flow...
Source: Health News from Medical News Today - March 14, 2013 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

Medtronic heart valve found to reduce death, stroke rate
(Reuters) - Medtronic Inc's CoreValve heart valve implant significantly lowered death and stroke rates in frail, elderly patients with severe aortic stenosis who were considered too ill for surgery, according to data from a late-stage clinical trial.
Source: Reuters: Health - October 29, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

COREVALVE reduces rate of death and stroke in sickest patients with aortic stenosis
In a clinical trial, a self-expanding transcatheter aortic valve met the key performance objective of reducing death and stroke in patients with severe aortic stenosis at "extreme risk" for surgery. Results of the COREVALVE EXTREME RISK trial were presented at the 25th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Sponsored by the Cardiovascular Research Foundation (CRF), TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine...
Source: Health News from Medical News Today - October 31, 2013 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

Relation Between Stroke Volume Index to Risk of Death in Patients With Low-Gradient Severe Aortic Stenosis and Preserved Left Ventricular Function
The aim of the present study was to evaluate whether assessment of stroke volume index (SVI) can be used to improve risk stratification among patients with low-gradient severe aortic stenosis and preserved ejection fraction (EF). Study population comprised 409 patients with aortic valve area ≤1.00 cm2, mean gradient
Source: The American Journal of Cardiology - May 19, 2014 Category: Cardiology Authors: Elad Maor, Roy Beigel, Avishay Grupper, Rafael Kuperstein, Ilan Hai, Diego Medvedofsky, Olga Perelstein, Israel Mazin, Asaf Ziv, Ilan Goldenberg, Micha S. Feinberg, Sagit Ben Zekry Tags: Valvular Heart Disease Source Type: research

Atrial Fibrillation, Stroke and Mortality Rates Following Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) is considered a suitable treatment for patients with severe symptomatic aortic stenosis (AS) and high operative risk. Our aim was to evaluate the effect of pre-procedural and new-onset atrial fibrillation (NOAF) on mortality and stroke in patients undergoing TAVI. We performed a single center study of 380 consecutive patients enrolled to a TAVI registry. NOAF was defined as post-procedural atrial fibrillation (AF) occurring within 30 days following the procedure.
Source: The American Journal of Cardiology - September 25, 2014 Category: Cardiology Authors: Lior Yankelson, Arie Steinvil, Liron Gershovitz, Eran Leshem-Rubinow, Ariel Furer, Sami Viskin, Gad Keren, Shmuel Banai, Ariel Finkelstein Source Type: research

Atrial Fibrillation, Stroke, and Mortality Rates After Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) is considered a suitable treatment for patients with severe symptomatic aortic stenosis and high operative risk. Our aim was to evaluate the effect of preprocedural and new-onset atrial fibrillation (NOAF) on mortality and stroke in patients who underwent TAVI. We performed a single-center study of 380 consecutive patients enrolled to a TAVI registry. NOAF was defined as postprocedural atrial fibrillation (AF) occurring within 30 days after the procedure.
Source: The American Journal of Cardiology - September 25, 2014 Category: Cardiology Authors: Lior Yankelson, Arie Steinvil, Liron Gershovitz, Eran Leshem-Rubinow, Ariel Furer, Sami Viskin, Gad Keren, Shmuel Banai, Ariel Finkelstein Tags: Valvular Heart Disease Source Type: research

Outcomes of surgical aortic valve replacement for severe aortic stenosis: Incorporation of left ventricular systolic function and stroke volume index
We sought to a) assess predictors of mortality in consecutive patients with severe aortic stenosis (AS) undergoing aortic valve replacement (AVR) and b) determine if there are differences in mortality, separated on the basis of different AS subtypes and left ventricular stroke volume index (LV-SVI).
Source: The Journal of Thoracic and Cardiovascular Surgery - March 11, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Roosha Parikh, Andrew L. Goodman, Tyler Barr, Joseph F. Sabik, Lars G. Svensson, L Leonardo Rodriguez, Bruce W. Lytle, Richard A. Grimm, Brian P. Griffin, Milind Y. Desai Source Type: research

Stroke Volume Adjusted to Afterload for Assessment of Cardiac Performance in Patients with Severe Aortic Stenosis and Preserved Left Ventricular Ejection Fraction
Objectives: The aim of this study was to evaluate the relationship between valvular resistance and stroke volume (SV) and to assess SV adequacy to afterload in patients with severe aortic stenosis (AS) and normal left ventricular ejection fraction (LVEF). Methods: We assessed clinical characteristics and echocardiographic parameters in 44 patients with isolated severe AS and preserved LVEF. LV end-diastolic pressure (LVEDP) and LV mean diastolic pressure (LVMDP) were measured by cardiac catheterization. SV values were plotted in relation to valvular resistance. Patients were divided into 2 groups, with an SV that was highe...
Source: Cardiology - March 20, 2015 Category: Cardiology Source Type: research

Meta-Analysis of the Prognostic Impact of Stroke Volume, Gradient and Ejection Fraction Following Transcatheter Aortic Valve Implantation
The prognostic implications of several baseline pre-procedural variables in patients with severe native valve aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) are unclear. The goal of this study was to determine the impact of reduced stroke volume index (SVI), low gradient (LG) and reduced ejection fraction (EF) on all-cause mortality. We searched MEDLINE, CENTRAL, EMBASE, Web of Science, and Scopus through 10/13/2014. We evaluated the association between low SVI (
Source: The American Journal of Cardiology - June 25, 2015 Category: Cardiology Authors: Mackram F. Eleid, Kashish Goel, M. Hassan Murad, Patricia J. Erwin, Rakesh M. Suri, Kevin L. Greason, Rick A. Nishimura, Charanjit S. Rihal, David R. Holmes Source Type: research

Meta-analysis of the Prognostic Impact of Stroke Volume, Gradient, and Ejection Fraction After Transcatheter Aortic Valve Implantation
The prognostic implications of several baseline preprocedural variables in patients with severe native valve aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) are unclear. The goal of this study was to determine the impact of reduced stroke volume index (SVI), low gradient (LG), and reduced ejection fraction (EF) on all-cause mortality. We searched MEDLINE, CENTRAL, EMBASE, Web of Science, and Scopus through October 13, 2014. We evaluated the association between low SVI (
Source: The American Journal of Cardiology - June 25, 2015 Category: Cardiology Authors: Mackram F. Eleid, Kashish Goel, M. Hassan Murad, Patricia J. Erwin, Rakesh M. Suri, Kevin L. Greason, Rick A. Nishimura, Charanjit S. Rihal, David R. Holmes Tags: Review Source Type: research

At 5 years, transcatheter aortic valve replacement had similar rates of mortality and stroke as surgical aortic valve replacement in high-risk patients
Commentary on: Kapadia SR, Leon MB, Makkar RR, et al., PARTNER trial investigators. 5-year outcomes of transcatheter aortic valve replacement compared with standard treatment for patients with inoperable aortic stenosis (PARTNER 1): a randomised controlled trial. Lancet 2015;385:2485–91 and Mack MJ, Leon MB, Smith CR, et al., PARTNER 1 trial investigators. 5-year outcomes of transcatheter aortic valve replacement or surgical aortic valve replacement for high surgical risk patients with aortic stenosis (PARTNER1): a randomised controlled trial. Lancet 2015;385:2477–84. Context When calcific aortic stenosis is as...
Source: Evidence-Based Medicine - November 24, 2015 Category: Internal Medicine Authors: Reardon, M. J., Kleiman, N. S. Tags: Clinical trials (epidemiology), Epidemiologic studies, Drugs: cardiovascular system, Heart failure, Stroke, Interventional cardiology, Valvar diseases Therapeutics/Prevention Source Type: research

Reducing periprocedural complications in transcatheter aortic valve replacement: review of paravalvular leaks, stroke and vascular complications.
Authors: Paradis JM, Altisent OA, RodÉs-Cabau J Abstract Transcatheter aortic valve replacement has been established as the standard of care for inoperable patients and a valid alternative for high-risk individuals with severe symptomatic native aortic stenosis. Over the last decade, substantial improvement has been made in the transcatheter technology. Nevertheless, this less-invasive procedure is still associated with complications like paravalvular leaks, strokes and vascular complications. This review article discusses these worrisome complications associated with transcatheter aortic valve replacement and pro...
Source: Expert Review of Cardiovascular Therapy - February 17, 2016 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

In severe aortic stenosis, TAVR was noninferior to conventional surgery for death or disabling stroke at 2 years.
PMID: 27538182 [PubMed - in process]
Source: Annals of Internal Medicine - August 15, 2016 Category: Internal Medicine Authors: Eagle KA, Weinberg RL Tags: Ann Intern Med Source Type: research

In severe aortic stenosis with intermediate surgical risk, TAVR was noninferior to SAVR for death or disabling stroke.
PMID: 28630980 [PubMed - in process]
Source: Annals of Internal Medicine - June 20, 2017 Category: Internal Medicine Authors: Spencer FA, Guyatt GH Tags: Ann Intern Med Source Type: research

Rapid Deployment Valve for Aortic Stenosis Ups Stroke Risk
FRIDAY, April 13, 2018 -- For patients with aortic valve stenosis, treatment with a rapid deployment valve (RDV) is associated with increased rates of new-onset pacemaker implantation and disabling stroke, compared with conventional biological...
Source: Drugs.com - Pharma News - April 13, 2018 Category: Pharmaceuticals Source Type: news